-
1
-
-
0028915934
-
Generation of a drug resistance profile by quantitation of mdr-1/P-glycoprotein in the cell lines of the NCI Anticancer Drug Screen
-
Alvarez M, Paull K, Monks A, Hose C, Lee JS, Weinstein J, Grever MR, Bates SE, and Fojo AT (1995) Generation of a drug resistance profile by quantitation of mdr-1/P-glycoprotein in the cell lines of the NCI Anticancer Drug Screen. J Clin Invest 95:2205-2214.
-
(1995)
J Clin Invest
, vol.95
, pp. 2205-2214
-
-
Alvarez, M.1
Paull, K.2
Monks, A.3
Hose, C.4
Lee, J.S.5
Weinstein, J.6
Grever, M.R.7
Bates, S.E.8
Fojo, A.T.9
-
2
-
-
0028809430
-
Expression of P-glycoprotein in high-grade osteosarcomas in relation to clinical outcome
-
Baldini N, Scotlandi K, Barbanti-Brodano G, Manara MC, Maurici D, Bacci G, Bertoni F, Picci P, Sottili S, Campanacci M, and Serra M (1995) Expression of P-glycoprotein in high-grade osteosarcomas in relation to clinical outcome. N Engl J Med 333:1380-1385.
-
(1995)
N Engl J Med
, vol.333
, pp. 1380-1385
-
-
Baldini, N.1
Scotlandi, K.2
Barbanti-Brodano, G.3
Manara, M.C.4
Maurici, D.5
Bacci, G.6
Bertoni, F.7
Picci, P.8
Sottili, S.9
Campanacci, M.10
Serra, M.11
-
3
-
-
0028945582
-
Expression of mdr1, mrp, topoisomerase IIα/B, and cyclin a in primary or relapsed states of acute lymphoblastic leukaemias
-
Beck J, Handgretinger R, Dopfer R, Klingebiel T, Niethammer D, and Gekeler V (1995) Expression of mdr1, mrp, topoisomerase IIα/B, and cyclin A in primary or relapsed states of acute lymphoblastic leukaemias. Br J Haematol 89:356-363.
-
(1995)
Br J Haematol
, vol.89
, pp. 356-363
-
-
Beck, J.1
Handgretinger, R.2
Dopfer, R.3
Klingebiel, T.4
Niethammer, D.5
Gekeler, V.6
-
4
-
-
0021952694
-
Isolation and characterization of an anthracycline-resistant human leukemic cell line
-
Bhalla K, Hindenburg A, Taub RN, and Grant S (1985) Isolation and characterization of an anthracycline-resistant human leukemic cell line. Cancer Res 45:3657-3662.
-
(1985)
Cancer Res
, vol.45
, pp. 3657-3662
-
-
Bhalla, K.1
Hindenburg, A.2
Taub, R.N.3
Grant, S.4
-
5
-
-
0028043795
-
Expression of the multidrug resistance-associated protein (MRP) gene correlates with amplification and overexpression of the N-myc oncogene in childhood neuroblastoma
-
Bordow SB, Haber M, Madafiglio J, Cheung B, Marshall GM, and Norris MD (1994) Expression of the multidrug resistance-associated protein (MRP) gene correlates with amplification and overexpression of the N-myc oncogene in childhood neuroblastoma. Cancer Res 54:5036-5040.
-
(1994)
Cancer Res
, vol.54
, pp. 5036-5040
-
-
Bordow, S.B.1
Haber, M.2
Madafiglio, J.3
Cheung, B.4
Marshall, G.M.5
Norris, M.D.6
-
6
-
-
0003088184
-
Data display and analysis strategies for the NCI Disease Oriented In-Vitro Antitumor Drug Screen
-
Valeriote FA, Corbett TH, and Baker LH, eds. Boston, Kluwer Academic Publishers
-
Boyd MR, Paull KD, and Rubinstein LR (1992) Data display and analysis strategies for the NCI Disease Oriented In-Vitro Antitumor Drug Screen, in Cytotoxic Anticancer Drugs: Models and Concept for Drug Discovery and Development (Valeriote FA, Corbett TH, and Baker LH, eds.) pp 11-34, Boston, Kluwer Academic Publishers.
-
(1992)
Cytotoxic Anticancer Drugs: Models and Concept for Drug Discovery and Development
, pp. 11-34
-
-
Boyd, M.R.1
Paull, K.D.2
Rubinstein, L.R.3
-
7
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-256.
-
(1976)
Anal Biochem
, vol.72
, pp. 248-256
-
-
Bradford, M.M.1
-
8
-
-
0028931885
-
Sequential coexpression of the multidrug resistance genes MRP and mdr1 and their products in VP-16 (etoposide)-selected H69 small cell lung cancer cells
-
Brock I, Hipfner DR, Nielsen BS, Jensen PB, Deeley RG, Cole SP, and Sehested M (1995) Sequential coexpression of the multidrug resistance genes MRP and mdr1 and their products in VP-16 (etoposide)-selected H69 small cell lung cancer cells. Cancer Res 55:459-462.
-
(1995)
Cancer Res
, vol.55
, pp. 459-462
-
-
Brock, I.1
Hipfner, D.R.2
Nielsen, B.S.3
Jensen, P.B.4
Deeley, R.G.5
Cole, S.P.6
Sehested, M.7
-
9
-
-
0023033333
-
Increased vinblastine binding to membrane vesicles from multidrug-resistant KB cells
-
Cornwell MM, Gottesman MM, and Pastan IH (1986) Increased vinblastine binding to membrane vesicles from multidrug-resistant KB cells. J Biol Chem 261:7921-7928.
-
(1986)
J Biol Chem
, vol.261
, pp. 7921-7928
-
-
Cornwell, M.M.1
Gottesman, M.M.2
Pastan, I.H.3
-
10
-
-
0029098798
-
An etoposide-resistant lung cancer subline overexpresses the multidrug resistance-associated protein
-
Doyle LA, Ross DD, Ordonez JV, Yang W, Gao Y, Tong Y, Belani CP, and Gutheil JC (1995) An etoposide-resistant lung cancer subline overexpresses the multidrug resistance-associated protein. Br J Cancer 72:535-542.
-
(1995)
Br J Cancer
, vol.72
, pp. 535-542
-
-
Doyle, L.A.1
Ross, D.D.2
Ordonez, J.V.3
Yang, W.4
Gao, Y.5
Tong, Y.6
Belani, C.P.7
Gutheil, J.C.8
-
11
-
-
0029074372
-
ATP-dependent efflux of calcein by the multidrug resistance protein (MRP): No inhibition by intracellular glutathione depletion
-
Feller N, Broxterman HJ, Wahrer DCR, and Pinedo HM (1995) ATP-dependent efflux of calcein by the multidrug resistance protein (MRP): no inhibition by intracellular glutathione depletion. FBBS Lett 368:385-388.
-
(1995)
FBBS Lett
, vol.368
, pp. 385-388
-
-
Feller, N.1
Broxterman, H.J.2
Wahrer, D.C.R.3
Pinedo, H.M.4
-
12
-
-
0029917028
-
Reductase enzyme expression across the National Cancer Institute tumor cell line panel: Correlation with sensitivity to mitomycin C and E09
-
Fitzsimmons SA, Workman P, Grever M, Paull K, Camalier R, and Lewis AD (1996) Reductase enzyme expression across the National Cancer Institute tumor cell line panel: correlation with sensitivity to mitomycin C and E09. J Natl Cancer Inst 88:259-269.
-
(1996)
J Natl Cancer Inst
, vol.88
, pp. 259-269
-
-
Fitzsimmons, S.A.1
Workman, P.2
Grever, M.3
Paull, K.4
Camalier, R.5
Lewis, A.D.6
-
13
-
-
0030897618
-
Identification of compounds with preferential inhibitory activity against low-Nm23-expressing human breast carcinoma and melanoma cell lines
-
Freije JM, Lawrence JA, Hollingshead MG, De la Rosa A, Narayanan V, Grever M, Sausville EA, Paull K, and Steeg PS (1997) Identification of compounds with preferential inhibitory activity against low-Nm23-expressing human breast carcinoma and melanoma cell lines. Nat Med 3:395-401.
-
(1997)
Nat Med
, vol.3
, pp. 395-401
-
-
Freije, J.M.1
Lawrence, J.A.2
Hollingshead, M.G.3
De La Rosa, A.4
Narayanan, V.5
Grever, M.6
Sausville, E.A.7
Paull, K.8
Steeg, P.S.9
-
14
-
-
0029018919
-
Expression of multidrug resistance-associated protein (MRP), MDR1 and DNA topoisomerase II in human multidrug-resistant bladder cancer cell lines
-
Hasegawa S, Abe T, Naito S, Kotoh S, Kumazawa J, Hipfner DR, Deeley RG, Cole SPC, and Kuwano M (1996) Expression of multidrug resistance-associated protein (MRP), MDR1 and DNA topoisomerase II in human multidrug-resistant bladder cancer cell lines. Br J Cancer 71:907-913.
-
(1996)
Br J Cancer
, vol.71
, pp. 907-913
-
-
Hasegawa, S.1
Abe, T.2
Naito, S.3
Kotoh, S.4
Kumazawa, J.5
Hipfner, D.R.6
Deeley, R.G.7
Cole, S.P.C.8
Kuwano, M.9
-
15
-
-
0024472768
-
2+ dependent cardiac transport system for glutathione S-conjugates: A study using rat heart sarcolemma vesicles
-
2+ dependent cardiac transport system for glutathione S-conjugates: a study using rat heart sarcolemma vesicles. J Biol Chem 264: 17343-17348.
-
(1989)
J Biol Chem
, vol.264
, pp. 17343-17348
-
-
Ishikawa, T.1
-
16
-
-
0027305406
-
Glutathione-associated cis-diamminedichloroplatinum (II) metabolism and ATP-dependent efflux from leukemia cells. Molecular characterization of glutathione-platinum complex and its biological significance
-
Ishikawa T and Ali-Osman F (1993) Glutathione-associated cis-diamminedichloroplatinum (II) metabolism and ATP-dependent efflux from leukemia cells. Molecular characterization of glutathione-platinum complex and its biological significance. J Biol Chem 268:20116-20125.
-
(1993)
J Biol Chem
, vol.268
, pp. 20116-20125
-
-
Ishikawa, T.1
Ali-Osman, F.2
-
17
-
-
0030063480
-
Transport of glutathione, glucuronate, and sulfate conjugates by the MRP gene-encoded conjugate export pump
-
Jedlitschky G, Leier I, Buchholz U, Barnouin K, Kurz G, and Keppler D (1996) Transport of glutathione, glucuronate, and sulfate conjugates by the MRP gene-encoded conjugate export pump. Cancer Res 56:988-994.
-
(1996)
Cancer Res
, vol.56
, pp. 988-994
-
-
Jedlitschky, G.1
Leier, I.2
Buchholz, U.3
Barnouin, K.4
Kurz, G.5
Keppler, D.6
-
18
-
-
0028001416
-
ATP-dependent transport of glutathion S-conjugates by multidrug resistance-associated protein
-
Jedlitschky G, Leier I, Buchholz U, Center M, and Keppler D (1994) ATP-dependent transport of glutathion S-conjugates by multidrug resistance-associated protein. Cancer Res 54:4833-4836.
-
(1994)
Cancer Res
, vol.54
, pp. 4833-4836
-
-
Jedlitschky, G.1
Leier, I.2
Buchholz, U.3
Center, M.4
Keppler, D.5
-
19
-
-
0028030228
-
Rhodamine efflux patterns predict P-glycoprotein substrates in the National Cancer Institute Drug Screen
-
Lee JS, Paull K, Alvarez M, Hose C, Monks A, Grever M, Fojo AT, and Bates SE (1994) Rhodamine efflux patterns predict P-glycoprotein substrates in the National Cancer Institute Drug Screen. Mol Pharmacol 46:627-638.
-
(1994)
Mol Pharmacol
, vol.46
, pp. 627-638
-
-
Lee, J.S.1
Paull, K.2
Alvarez, M.3
Hose, C.4
Monks, A.5
Grever, M.6
Fojo, A.T.7
Bates, S.E.8
-
20
-
-
0028347079
-
Characterization of the ATP-dependent leukotrien C4 export carrier in mastocytoma cells
-
Leier I, Jedlitschky G, Buchholz U, and Keppler D (1994) Characterization of the ATP-dependent leukotrien C4 export carrier in mastocytoma cells. Ear J Biochem 220:599-606.
-
(1994)
Ear J Biochem
, vol.220
, pp. 599-606
-
-
Leier, I.1
Jedlitschky, G.2
Buchholz, U.3
Keppler, D.4
-
21
-
-
0029096486
-
- cases
-
- cases. Blood 86:2329-2342.
-
(1995)
Blood
, vol.86
, pp. 2329-2342
-
-
Leith, C.P.1
Chen, I.M.2
Kopecky, K.J.3
Appelbaum, F.R.4
Head, D.R.5
Godwin, J.E.6
Weick, J.K.7
Willman, C.L.8
-
22
-
-
0029918142
-
ATP-dependent 17 β-estradiol 17-(β-D-glucuronide) transport by multidrug resistance protein (MRP)
-
Loe DW, Almquist KC, Cole SPC, and Deeley RG (1996a) ATP-dependent 17 β-estradiol 17-(β-D-glucuronide) transport by multidrug resistance protein (MRP). J Biol Chem 271:9683-9689.
-
(1996)
J Biol Chem
, vol.271
, pp. 9683-9689
-
-
Loe, D.W.1
Almquist, K.C.2
Cole, S.P.C.3
Deeley, R.G.4
-
23
-
-
0030009305
-
Multidrug resistance protein (MRP)-mediated transport of leukotriene C4 and chemotherapeutic agents in membrane vesicles: Demonstration of glutathione-dependent vincristine transport
-
Loe DW, Almquist KC, Deeley RG, and Cole SPC (1996b) Multidrug resistance protein (MRP)-mediated transport of leukotriene C4 and chemotherapeutic agents in membrane vesicles: demonstration of glutathione-dependent vincristine transport. J Biol Chem 271:9675-9682.
-
(1996)
J Biol Chem
, vol.271
, pp. 9675-9682
-
-
Loe, D.W.1
Almquist, K.C.2
Deeley, R.G.3
Cole, S.P.C.4
-
24
-
-
0030694313
-
Cellular adaptation to drug exposure: Evolution of the drug-resistant phenotype
-
Matsumoto Y, Takano H, and Fojo T (1997) Cellular adaptation to drug exposure: evolution of the drug-resistant phenotype. Cancer Res 57:5086-5092.
-
(1997)
Cancer Res
, vol.57
, pp. 5086-5092
-
-
Matsumoto, Y.1
Takano, H.2
Fojo, T.3
-
25
-
-
0025775062
-
Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines
-
Monks A, Scudiero D, Skehan P, Shoemaker R, Paull K, Vistica D, Hose C, Langley J, Cronise P, Vaigro-Wolff A, Gray-Goodrich M, Campbell H, Mayo J, and Boyd M (1991) Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines. J Natl Cancer Inst 83:757-766.
-
(1991)
J Natl Cancer Inst
, vol.83
, pp. 757-766
-
-
Monks, A.1
Scudiero, D.2
Skehan, P.3
Shoemaker, R.4
Paull, K.5
Vistica, D.6
Hose, C.7
Langley, J.8
Cronise, P.9
Vaigro-Wolff, A.10
Gray-Goodrich, M.11
Campbell, H.12
Mayo, J.13
Boyd, M.14
-
26
-
-
0028578004
-
Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport
-
Muller M, Meijer C, Zaman GJR, Borst P, Scheper RJ, Mulder NH, deVries EGE, and Jansen PLM (1994) Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport. Proc Natl Acad Sci USA 91:13033-13037.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 13033-13037
-
-
Muller, M.1
Meijer, C.2
Zaman, G.J.R.3
Borst, P.4
Scheper, R.J.5
Mulder, N.H.6
DeVries, E.G.E.7
Jansen, P.L.M.8
-
27
-
-
0030865104
-
Characterization of the p52 tumor suppressor pathway in cell lines of the National Cancer Institute anticancer drug screen and correlations with the growth-inhibitory potency of 123 anticancer drugs
-
O'Connor PM, Jackman J, Bae I, Myers TG, Fan S, Mutoh M, Scudiero DA, Monks A, Sausville EA, Weinstein JN, Friend S Jr, Fornace AJ, and Kohn KW (1997) Characterization of the p52 tumor suppressor pathway in cell lines of the National Cancer Institute anticancer drug screen and correlations with the growth-inhibitory potency of 123 anticancer drugs. Cancer Res 57:4285-4300.
-
(1997)
Cancer Res
, vol.57
, pp. 4285-4300
-
-
O'Connor, P.M.1
Jackman, J.2
Bae, I.3
Myers, T.G.4
Fan, S.5
Mutoh, M.6
Scudiero, D.A.7
Monks, A.8
Sausville, E.A.9
Weinstein, J.N.10
Friend Jr., S.11
Fornace, A.J.12
Kohn, K.W.13
-
28
-
-
0003154873
-
Prediction of biochemical mechanisms of action from the in vitro antitumor screen of the National Cancer Institute
-
Foye WE, ed. Washington, DC, American Chemical Society
-
Paull KD, Hamel E, and Malspeis L (1995) Prediction of biochemical mechanisms of action from the in vitro antitumor screen of the National Cancer Institute, in Cancer Chemotherapeutic Agents (Foye WE, ed.) pp 9-45, Washington, DC, American Chemical Society.
-
(1995)
Cancer Chemotherapeutic Agents
, pp. 9-45
-
-
Paull, K.D.1
Hamel, E.2
Malspeis, L.3
-
29
-
-
0026752669
-
Identification of novel antimitotic agents acting at the tubulin level by computer-assisted evaluation of differential cytotoxicity data
-
Paull KD, Lin CM, Malspeis L, and Hamel E (1992) Identification of novel antimitotic agents acting at the tubulin level by computer-assisted evaluation of differential cytotoxicity data. Cancer Res 52:3892-3900.
-
(1992)
Cancer Res
, vol.52
, pp. 3892-3900
-
-
Paull, K.D.1
Lin, C.M.2
Malspeis, L.3
Hamel, E.4
-
30
-
-
0024312538
-
Display and analysis of patterns of differential activity of drugs against human tumor cell lines: Development of mean graph and Compare algorithm
-
Paull KD, Shoemaker RH, Hodes L, Monks A, Scudiero DA, Rubinstein L, Plowman J, and Boyd MR (1989) Display and analysis of patterns of differential activity of drugs against human tumor cell lines: development of mean graph and Compare algorithm. J Natl Cancer Inst 81:1088-1092.
-
(1989)
J Natl Cancer Inst
, vol.81
, pp. 1088-1092
-
-
Paull, K.D.1
Shoemaker, R.H.2
Hodes, L.3
Monks, A.4
Scudiero, D.A.5
Rubinstein, L.6
Plowman, J.7
Boyd, M.R.8
-
31
-
-
0028009810
-
Multidrug resistance-associated protein gene overexpression and reduced drug sensitivity of topoisomerase II in a human breast carcinoma MCF7 cell line selected for etopside resistance
-
Schneider E, Horton JK, Yang C, Nakagawa M, and Cowan KC (1994) Multidrug resistance-associated protein gene overexpression and reduced drug sensitivity of topoisomerase II in a human breast carcinoma MCF7 cell line selected for etopside resistance. Cancer Res 54:152-158.
-
(1994)
Cancer Res
, vol.54
, pp. 152-158
-
-
Schneider, E.1
Horton, J.K.2
Yang, C.3
Nakagawa, M.4
Cowan, K.C.5
-
32
-
-
0030009829
-
Cellular and in vitro transport of glutathione conjugates by MRP
-
Shen H, Paul S, Breuninger LM, Ciaccio PJ, Laing NM, Helt J, Tew KD, and Kruh GD (1996) Cellular and in vitro transport of glutathione conjugates by MRP. Biochem 35:5719-5723.
-
(1996)
Biochem
, vol.35
, pp. 5719-5723
-
-
Shen, H.1
Paul, S.2
Breuninger, L.M.3
Ciaccio, P.J.4
Laing, N.M.5
Helt, J.6
Tew, K.D.7
Kruh, G.D.8
-
33
-
-
0025341331
-
New colorimetric cytotoxicty assay for anticancer-drug screening
-
Skehan P, Storeng R, Scudiero D, Monks A, McMahon J, Vistica D, Warren JT, Bokesch H, Kenney S, and Boyd MR (1990) New colorimetric cytotoxicty assay for anticancer-drug screening. J Natl Cancer Inst 82:1107-1112,
-
(1990)
J Natl Cancer Inst
, vol.82
, pp. 1107-1112
-
-
Skehan, P.1
Storeng, R.2
Scudiero, D.3
Monks, A.4
McMahon, J.5
Vistica, D.6
Warren, J.T.7
Bokesch, H.8
Kenney, S.9
Boyd, M.R.10
-
34
-
-
0029642277
-
On the relationship between the probenecid-sensitive transport of daunorubicin or calcein and the glutathione status of cells overexpressing the multidrug resistance-associated protein (MRP)
-
Versantvoort CHM, Bagrij T, Wright KA, and Twentyman PR (1995) On the relationship between the probenecid-sensitive transport of daunorubicin or calcein and the glutathione status of cells overexpressing the multidrug resistance-associated protein (MRP). Int J Cancer 63:855-862.
-
(1995)
Int J Cancer
, vol.63
, pp. 855-862
-
-
Versantvoort, C.H.M.1
Bagrij, T.2
Wright, K.A.3
Twentyman, P.R.4
-
35
-
-
3643138602
-
Identification of epidermal growth factor receptor and c-erbB2 pathway inhibitors by correlation with gene expression patterns
-
Wosikowski K, Schuurhuis D, Johnson K, Paull KD, Myers TG, Weinstein JN, and Bates SE (1997) Identification of epidermal growth factor receptor and c-erbB2 pathway inhibitors by correlation with gene expression patterns. Cancer Res 57:4285-4300.
-
(1997)
Cancer Res
, vol.57
, pp. 4285-4300
-
-
Wosikowski, K.1
Schuurhuis, D.2
Johnson, K.3
Paull, K.D.4
Myers, T.G.5
Weinstein, J.N.6
Bates, S.E.7
-
36
-
-
0029095763
-
Role of glutathione in the export of compounds from cells by the multidrug-resistance-associated protein
-
Zaman GJR, Lankelma J, van Tellingen O, Beijen J, Dekker H, Paulusma C, Oude Elferink RPJ, Baas F, and Borst P (1995) Role of glutathione in the export of compounds from cells by the multidrug-resistance-associated protein. Proc Natl Acad Sci USA 92:7690-7694.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 7690-7694
-
-
Zaman, G.J.R.1
Lankelma, J.2
Van Tellingen, O.3
Beijen, J.4
Dekker, H.5
Paulusma, C.6
Oude Elferink, R.P.J.7
Baas, F.8
Borst, P.9
-
37
-
-
0030915104
-
Expression of the multidrug resistance-associated protein gene in refractory lymphoma: Quantitation by a validated polymerase chain reaction assay
-
Zhan Z, Sandor VA, Gamelin E, Regis J, Dickstein B, Wilson W, Fojo AT, and Bates SE (1997) Expression of the multidrug resistance-associated protein gene in refractory lymphoma: quantitation by a validated polymerase chain reaction assay. Blood 89:3795-3800.
-
(1997)
Blood
, vol.89
, pp. 3795-3800
-
-
Zhan, Z.1
Sandor, V.A.2
Gamelin, E.3
Regis, J.4
Dickstein, B.5
Wilson, W.6
Fojo, A.T.7
Bates, S.E.8
|