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57
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0001943172
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note
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Position numberings in this letter are according to those of CTX1 B.
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61
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0000241349
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4; BnBr, t-BuOK, TBAI; 6M HCl-THF (1:1); 83% total yield] from (2S, 3R)-2-(2-propenyl)-3-hydroxyoxane (98%ee) which was synthesized according to the following paper: K. Fujiwara, K. Saka, D. Takaoka, and A. Murai, Synlett, 1999, 1037.
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note
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Treatment of 8a or 8b with thexylborane followed by oxidation could not improve the ratio of 9 to 10. In each case, the production of 5, which would resulted from 1,2-elimination in the corresponding hydroboration product having a 2-alkoxyalkylborane system, was mainly observed.
-
-
-
-
71
-
-
84985702456
-
-
was applied to diol 20b, the reaction could not finish and gave a mixture of the corresponding iodide and 21b. Further treatment of the mixture with Zn was required for the complete conversion to 21b
-
When Samuelsson's method (P. J. Garegg and B. Samuelsson, Synthesis, 1979, 469) was applied to diol 20b, the reaction could not finish and gave a mixture of the corresponding iodide and 21b. Further treatment of the mixture with Zn was required for the complete conversion to 21b.
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Synthesis
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Garegg, P.J.1
Samuelsson, B.2
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