Convergent Synthesis of a Trans-fused 6-7-6 Tricyclic Ether System Based on a Ring-closing Metathesis Reaction

Synlett

Volumn 1997, Issue 8, 1997, Pages 980-982

  Oishi, Tohru ^a   Nagumo, Yoko ^a   Hirama, Masahiro ^a  

^a TOHOKU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0001777309     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-1997-969     Document Type: Article

References (27)

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17. Optical purities of (-)-9 and (+)-9 derived from (+)-8 were determined by HPLC analysis (DAICEL, CHIRALPAK AS, hexane/2-propanol=20/1, 1.0 mL/min, 254 nm).
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19. The stereochemistry of 3 was determined by NOE experiments. 3 should be more stable than the stereoisomer 3a. (Matrix Presented)
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26. Wittig reaction resulted in a low yield (38%) and 12% of the aldehyde was recovered.
27. -. NaHMDS, THF; (b) Tebbe reagent, toluene, THF.