Transcriptional targets shared by estrogen receptor-related receptors (ERRs) and estrogen receptor (ER) α, but not by ERβ

EMBO Journal

Volumn 18, Issue 15, 1999, Pages 4270-4279

  Vanacker, Jean Marc ^a   Pettersson, Katarina ^b   Gustafsson, Jan Åke ^b   Laudet, Vincent ^a  

^a UNIVERSITÉ DE LYON   (France)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Estrogen; Nuclear receptors; Orphan receptors; Transcriptional interference

Indexed keywords

CELL NUCLEUS RECEPTOR; DNA; ESTROGEN RECEPTOR; OSTEOPONTIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; GENE SEQUENCE; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; RAT; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION;

ANIMALS; BASE SEQUENCE; DNA; DNA-BINDING PROTEINS; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; GENE EXPRESSION REGULATION; HELA CELLS; HUMANS; OSTEOPONTIN; PROMOTER REGIONS (GENETICS); RATS; RECEPTORS, ESTROGEN; SIALOGLYCOPROTEINS; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED;

ANIMALIA;

EID: 0033517107     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/18.15.4270     Document Type: Article

References (35)

1. Bonnelye, E., Vanacker, J.M., Dittmar, T., Begue, A., Desbiens, X., Denhardt, D.T., Aubin, J.E., Laudet, V. and Fournier, B. (1997a) The ERR-1 orphan receptor is a transcriptional activator expressed during bone development. Mol. Endocrinol., 11, 905-916.
2. Bonnelye, E., Vanacker, J.M., Spruyt, N., Alric, S., Fournier, B., Desbiens, X. and Laudet, V. (1997b) Expression of the estrogen-related receptor 1 (ERR-1) orphan receptor during mouse development. Mech. Dev., 65, 71-85.
3. Craig, A.M. and Denhardt, D.T. (1991) The murine gene encoding secreted phosphoprotein 1 (osteopontin): promoter structure, activity and induction in vivo by estrogen and progesterone. Gene, 100, 163-171.
4. Craig, A.M., Smith, J.H. and Denhardt, D.T. (1989) Osteopontin, a transformation-associated cell adhesion phosphoprotein, is induced by 12-O-tetradecanoylphorbol 13-acetate in mouse epidermis. J. Biol. Chem., 264, 9682-9689.
5. Cowley, S.M., Hoare, S., Mosselman, S. and Parker, M.G. (1997) Estrogen receptors alpha and beta form heterodimers on DNA. J. Biol. Chem., 272, 19858-19862.
6. Denhardt, D.T. and Guo, X. (1993) Osteopontin: a protein of many functions. FASEB J., 7, 1475-1482.
7. Elgort, M.G., Zou, A., Marschke, K.B. and Allegretto, E.A. (1996) Estrogen and estrogen receptor antagonists stimulate transcription from the human retinoic acid receptor-α 1 promoter via a novel sequence. Mol. Endocrinol., 10, 477-487.
8. Enmark, E. and Gustafsson, J.-Å. (1996) Orphan nuclear receptors: the first eight years. Mol. Endocrinol., 10, 1293-1307.
9. Eriksen, E.F., Colvard, D.S., Berg, N.J., Graham, M.L., Mann, K.G., Spelsberg, T.C. and Riggs, B.L. (1988) Evidence of estrogen receptors in normal human osteoblast-like cells. Science, 241, 84-86.
10. Giguère, V., Yang, N., Segui, P. and Evans, R.M. (1988) Identification of a new class of steroid hormone receptors. Nature, 331, 91-94.
11. Giguère, V., Tremblay, A. and Tremblay, G.B. (1998) Estrogen receptor beta: re-evaluation of estrogen and antiestrogen signaling. Steroids, 63, 335-339.
12. Glass, C.K. (1994) Differential recognition of target genes by nuclear receptor monomers, dimers, and heterodimers. Endocrinol. Rev., 15, 391-407.
13. Green, S., Walter, P, Kumar, V., Krust, A., Bornert, J.M., Argos, P. and Chambon, P. (1986) Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A. Nature, 320, 134-139.
14. Gronemeyer, H. and Laudet, V. (1995) Transcription factors 3: nuclear receptors. Protein Profile, 2, 1173-1308.
15. Guo, X., Zhang, Y.P., Mitchell, D.A., Denhardt, D.T. and Chambers, A.F. (1995) Identification of a ras-activated enhancer in the mouse osteopontin promoter and its interaction with a putative ETS-related transcription factor whose activity correlates with the metastatic potential of the cell. Mol. Cell. Biol., 15, 476-487.
16. Ince, B.A., Schodin, D.J., Shapiro, D.J. and Katzenellenbogen, B.S. (1995) Repression of endogenous estrogen receptor activity in MCF7 human breast cancer cells by dominant negative estrogen receptors. Endocrinology, 136, 3194-3199.
17. Komm, B.S., Terpening, C.M., Benz, D.J., Graeme, K.A., Gallegos, A., Korc, M., Greene, G.L., O'Malley, B.W. and Haussler, M.R. (1988) Estrogen binding, receptor mRNA and biological response in osteoblast-like osteosarcoma cells. Science, 241, 81-84.
18. Korach, K.S. (1994) Insights from the study of animals lacking functional estrogen receptor. Science, 266, 1524-1527.
19. Kuiper, G.G.J.M., Enmark, E., Pelto-Huikko, M., Nilsson, S. and Gustafsson, J.-Å. (1996) Cloning of a novel estrogen receptor expressed in rat prostate and ovary. Proc. Natl Acad. Sci. USA, 93, 5925-5930.
20. Kuiper, G.G.J.M., Carlsson, B., Grandien, K., Enmark, E., Häggblad, J., Nilsson, S. and Gustafsson, J.-Å. (1997) Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors α and β. Endocrinology, 138, 863-870.
21. Laudet, V. (1997) Evolution of the nuclear receptor superfamily: early diversification from an ancestral orphan receptor. J. Mol. Endocrinol., 19, 207-226.
22. Mangelsdorf, D.J. et al. (1995) The nuclear receptor superfamily: the second decade. Cell, 83, 835-839.
23. Noda, M., Vogel, R.L., Craig, A.M., Prahl, J., DeLuca, H.F. and Denhardt, D.T. (1990) Identification of a DNA sequence responsible for binding of the 1,25-dihydroxyvitamin D3 receptor and 1,25 dihydroxyvitamin D3 enhancement of mouse secreted phosphoprotein 1 (Sppl or osteopontin) gene expression. Proc. Natl Acad. Sci. USA, 87, 9995-9999.
24. Nuclear Receptors Nomenclature Committee (1999) Cell, 97, 161-163.
25. Onoe, Y., Miyaura, C., Ohta, H., Nozawa, S. and Suda, T. (1997) Expression of estrogen receptor beta in rat bone. Endocrinology, 138, 4509-4512.
26. Pacifici, R. (1996) Estrogen, cytokines and pathogenesis of postmenopausal osteoporosis. J. Bone Miner. Res., 11, 1043-1051.
27. Paech, K., Webb, P., Kuiper, G.G.J.M., Nilsson, S., Gustafsson, J.-Å., Kushner, P.J. and Scanlan, T. (1997) Differential ligand activation of estrogen receptors ERα and ERβ at AP1 sites. Science, 277, 1508-1510.
28. Pettersson, K., Svensson, K., Mattsson, R., Carlsson, B., Ohlsson, R. and Berkenstam, A. (1996) Expression of a novel member of estrogen response element-binding nuclear receptors is restricted to the early stages of chorion formation during mouse embryogenesis. Mech. Dev., 54, 211-223.
29. Pettersson, K., Grandien, K., Kuiper, G.G.J.M. and Gustafsson, J.-Å. (1997) Mouse estrogen receptor β forms estrogen response element-binding heterodimers with estrogen receptor α. Mol. Endocrinol., 11, 1486-1496.
30. Shigeta, H., Zuo, W., Yang, N., DiAugustine, R. and Teng, C.T. (1997) The mouse estrogen receptor-related orphan receptor α1 : molecular cloning and estrogen responsiveness. J. Mol. Endocrinol., 19, 299-309.
31. Turner, R.T., Riggs, B.L. and Spelsberg, T.C. (1994) Skeletal effects of estrogen. Endocrinol. Rev., 15, 275-300.
32. Vanacker, J.-M., Delmarre, C., Guo, X. and Laudet, V. (1998a) Activation of the osteopontin promoter by the orphan nuclear receptor ERRα. Cell Growth Differ., 9, 1007-1014.
33. Vanacker, J.M., Bonnelye, E., Delmarre, C. and Laudet, V. (1998b) Activation of the thyroid hormone receptor α gene promoter by the orphan nuclear receptor ERRα. Oncogene, 17, 2429-2435.
34. Vanacker, J.M., Bonnelye, E., Chopin-Delannoy, Delmarre, C., Cavaillès, V. and Laudet, V. (1999) Transcriptional activities of the orphan nuclear receptor ERRα. Mol. Endocrinol., 13, 764-773.
35. Wilson, T.E., Fahrner, T.J. and Milbrandt, J. (1993) The orphan receptor NGF1-B and steroidogenic factor 1 establish monomer binding as a third paradigm of nuclear receptor DNA interaction. Mol. Cell. Biol., 13, 5794-5804.