Reversible immortalization of mammalian cells mediated by retroviral transfer and site-specific recombination

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 17, 1996, Pages 8971-8976

  Westerman, Karen A ^a   Leboulch, Philippe ^a,b  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

FLP and Cre recombinases; gene therapy; replicative cell senescence; simian virus 40 large T; telomeres

Indexed keywords

RECOMBINASE;

ANIMAL CELL; ARTICLE; CELL DEGENERATION; CELL GROWTH; CONTROLLED STUDY; GENE THERAPY; GENE TRANSFER; GENETIC RECOMBINATION; MAMMAL CELL; MOUSE; NONHUMAN; ONCOGENE; PRIORITY JOURNAL; RETROVIRUS; SENESCENCE; TELOMERE; VIRUS GENE;

3T3 CELLS; ANIMALS; CATTLE; CELL AGING; CELL LINE, TRANSFORMED; CELL TRANSFORMATION, VIRAL; DNA NUCLEOTIDYLTRANSFERASES; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HUMANS; INTEGRASES; KIDNEY; MICE; MUSCLE, SMOOTH, VASCULAR; RABBITS; RECOMBINATION, GENETIC; SIMIAN VIRUS 40; SKIN; TELOMERE; TRANSDUCTION, GENETIC; VIRAL PROTEINS;

ANIMALIA; MAMMALIA; SIMIAE; SIMIAN VIRUS; SIMIAN VIRUS 40; UNIDENTIFIED RETROVIRUS;

EID: 0029810898     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.17.8971     Document Type: Article

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