Transient oxidative stress in SH-SY5Y human neuroblastoma cells results in caspase dependent and independent cell death and tau proteolysis

Journal of Neuroscience Research

Volumn 61, Issue 5, 2000, Pages 515-523

  Krishnamurthy, Pavan K ^a   Mays, John L ^a   Bijur, Gautam N ^a   Johnson, Gail V W ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Apoptosis; Caspase 3; Ischemia; Necrosis; Tert butyl hydroperoxide

Indexed keywords

BUTYL HYDROPEROXIDE; BUTYLATED HYDROXYANISOLE; CASPASE 3; FREE RADICAL; LACTATE DEHYDROGENASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE;

APOPTOSIS; ARTICLE; CELL DEATH; CELL SURVIVAL; CHROMATIN CONDENSATION; CYTOLYSIS; DISEASE SEVERITY; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; ISCHEMIA; NECROSIS; NERVE DEGENERATION; NEUROBLASTOMA CELL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEGRADATION;

EID: 0034284480     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-4547(20000901)61:5<515::aid-jnr6>3.0.co;2-%23     Document Type: Article

References (51)

1. Mammalian cell death proteases: A family of highly conserved aspartate specific cysteine proteases
2. In the neuronal cell line SH-SY5Y, oxidative stress-induced free radical overproduction causes cell death without any participation of intracellular Ca(2+) increase
3. Postischemic administration of AK275, a calpain inhibitor, provides substantial protection against focal ischemic brain damage
4. Aging, energy, and oxidative stress in neurodegenerative diseases
5. Alzheimer disease and oxidative stress: Implications for novel therapeutic approaches
6. The participation of coenzyme Q in free radical production and antioxidation
7. The distribution of tau in the mammalian central nervous system
8. Tau cleavage and dephosphorylation in cerebellar granule neurons undergoing apoptosis
9. The structural basis of monoclonal antibody Alz50's selectivity for Alzheimer disease pathology
10. Role of oxidants in ischemic brain damage
11. Calcium: Still center-stage in hypoxic-ischemic neuronal death
12. Oxidative stress, glutamate, and neurodegenerative disorders
13. Regulation of gene expression by reactive oxygen
14. Select alterations in protein kinases and phosphatases during apoptosis of differentiated PC12 cells
15. Role of oxygen free radicals in cancer development
16. Proteolytic activation of protein kinase C delta by an ICE/CED 3-like protease induces characteristics of apoptosis
17. Cloning and sequencing of the cDNA encoding an isoform of microtubule-associated protein tau containing four tandem repeats: Differential expression of tau protein mRNAs in human brain
18. SAPK2/p38-dependent F-actin reorganization regulates early membrane blebbing during stress-induced apoptosis
19. The tau protein in human cerebrospinal fluid in Alzheimer disease consists of proteolytically derived fragments
20. Ischemia-induced death of astrocytes and neurons in primary, culture: Pitfalls in quantifying neuronal cell death
21. Bcl-2 inhibition of neural death: Decreased generation of reactive oxygen species
22. Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
23. The shape of cell death
24. Intracellular adenosine triphosphate (ATP) concentration: A switch in the decision between apoptosis and necrosis
25. Inhibition of caspase activity induces a switch from apoptosis to necrosis
26. 2+ increases and cell death
27. Proteolysis of fodrin (non-erythroid spectrin) during apoptosis
28. Mitochondrial damage as a mechanism of cell injury in the killing of cultured hepatocytes by tert-butyl hydroperoxide
29. Actin cleavage by CPP-32/apopain during the development of apoptosis
30. Involvement of caspases in sympathetic neuron apoptosis
31. Bax deletion further orders the cell death pathway in cerebellar granule cells and suggests a caspase-independent pathway to cell death
32. Activation of a PP2A-like phosphatase and dephosphorylation of tau protein characterize onset of the execution phase of apoptosis
33. Extranuclear apoptosis. The role of the cytoplasm in the execution phase
34. Free radical-mediated effects on skeletal muscle protein in rats treated with Fe-nitrilotriacetate
35. Non-erythroid alpha-spectrin breakdown by calpain and interleukin 1 beta-converting-enzyme-like protease(s) in apoptotic cells: Contributory roles of both protease families in neuronal apoptosis
36. Caspase structure, proteolytic substrates, and function during apoptotic cell death
37. Caspases: Killer proteases
38. 2+ concentration and cytotoxicity in hepatocytes exposed to oxidative stress
39. Conditions allowing redox-cycling ubisemiquinone in mitochondria to establish a direct redox couple with molecular oxygen
40. Mechanisms of cell death induced by the mitochondrial toxin 3- nitroproprionic acid: Acute excitotoxic necrosis and delayed apoptosis
41. G1/S cell cycle blockers and inhibitors of cyclin-dependent kinases suppress camptothecin-induced neuronal apoptosis
42. The role of proteases during apoptosis
43. Regional calpain and caspase-3 proteolysis of alpha-spectrin after traumatic brain injury
44. Oxidative stress induces apoptosis in embryonic cortical neurons
45. Oxidative stress: From basic research to clinical application
46. Caspase-dependent and -independent death of camptothecin-treated embryonic cortical neurons
47. Caspase-2 (Nedd-2) processing and death of trophic factor-deprived PC12 cells and sympathetic neurons occur independently of caspase-3 (CPP32)- like activity
48. Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase
49. Calpain inhibition: An overview of its therapeutic potential
50. Cell death: The significance of apoptosis