-
1
-
-
0028229147
-
Inactivation of E2a in recombinant adenoviruses improves the prospect for gene therapy in cystic fibrosis
-
Yang Y, Nunes FA, Berencsi K, Gonczol E, Engelhardt JF, Wilson JM. Inactivation of E2a in recombinant adenoviruses improves the prospect for gene therapy in cystic fibrosis. Nat Genet 1994; 7: 362-369.
-
(1994)
Nat Genet
, vol.7
, pp. 362-369
-
-
Yang, Y.1
Nunes, F.A.2
Berencsi, K.3
Gonczol, E.4
Engelhardt, J.F.5
Wilson, J.M.6
-
2
-
-
0029838375
-
A gene transfer vector-cell line system for complete functional complementation of adenovirus early regions E1 and E4
-
Brough DE, Lizonova A, Hsu C, Kulesa VA, Kovesdi I. A gene transfer vector-cell line system for complete functional complementation of adenovirus early regions E1 and E4. J Virol 1996; 70: 6497-6501.
-
(1996)
J Virol
, vol.70
, pp. 6497-6501
-
-
Brough, D.E.1
Lizonova, A.2
Hsu, C.3
Kulesa, V.A.4
Kovesdi, I.5
-
3
-
-
0029582770
-
A packaging cell line for propagation of recombinant adenovirus vectors containing two lethal gene-region deletion
-
Wang Q, Jia XC, Finer MH. A packaging cell line for propagation of recombinant adenovirus vectors containing two lethal gene-region deletion. Gene Ther 1995; 2: 775-783.
-
(1995)
Gene Ther
, vol.2
, pp. 775-783
-
-
Wang, Q.1
Jia, X.C.2
Finer, M.H.3
-
4
-
-
0028863880
-
Characterization of an adenovirus gene transfer vector containing an E4 deletion
-
Armentano D, Sookdeo CC, Hehir KM, et al. Characterization of an adenovirus gene transfer vector containing an E4 deletion. Hum Gene Ther 1995; 6: 1343-1353.
-
(1995)
Hum Gene Ther
, vol.6
, pp. 1343-1353
-
-
Armentano, D.1
Sookdeo, C.C.2
Hehir, K.M.3
-
5
-
-
0029664338
-
Elimination of both E1 and E2a from adenovirus vectors further improves prospects for in vivo human gene therapy
-
Gorziglia MI, Kadan MJ, Yei S, et al. Elimination of both E1 and E2a from adenovirus vectors further improves prospects for in vivo human gene therapy. J Virol 1996; 70: 4173-4178.
-
(1996)
J Virol
, vol.70
, pp. 4173-4178
-
-
Gorziglia, M.I.1
Kadan, M.J.2
Yei, S.3
-
6
-
-
0030892490
-
Isolation and characterization of packaging cell lines that coexpress the adenovirus E1, DNA polymerase, and preterminal proteins - Implications for gene therapy
-
Amalfitano A, Chamberlain JS. Isolation and characterization of packaging cell lines that coexpress the adenovirus E1, DNA polymerase, and preterminal proteins - implications for gene therapy. Gene Ther 1997; 4: 258-263.
-
(1997)
Gene Ther
, vol.4
, pp. 258-263
-
-
Amalfitano, A.1
Chamberlain, J.S.2
-
7
-
-
0031055468
-
Construction of adenovirus vectors through cre-lox recombination
-
Hardy S, Kitamura M, Harrisstansil T, Dai YM, Phipps ML. Construction of adenovirus vectors through cre-lox recombination. J Virol 1997; 71: 1842-1849.
-
(1997)
J Virol
, vol.71
, pp. 1842-1849
-
-
Hardy, S.1
Kitamura, M.2
Harrisstansil, T.3
Dai, Y.M.4
Phipps, M.L.5
-
8
-
-
0030900511
-
A helper-dependent system for adenovirus vector production helps define a lower limit for efficient DNA packaging
-
Parks RJ, Graham FL. A helper-dependent system for adenovirus vector production helps define a lower limit for efficient DNA packaging. J Virol 1997; 71: 3293-3298.
-
(1997)
J Virol
, vol.71
, pp. 3293-3298
-
-
Parks, R.J.1
Graham, F.L.2
-
9
-
-
0029054932
-
Rescue, propagation, and partial purification of a helper virus-dependent adenovirus vector
-
Mitani K, Graham FL, Caskey CT, Kochanek S. Rescue, propagation, and partial purification of a helper virus-dependent adenovirus vector. Proc Natl Acad Sci U S A 1995; 92: 3854-3858.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 3854-3858
-
-
Mitani, K.1
Graham, F.L.2
Caskey, C.T.3
Kochanek, S.4
-
10
-
-
0029943155
-
A new adenoviral vector - Replacement of all viral coding sequences with 28 kb of DNA independently expressing both full-length dystrophin and beta-galactosidase
-
Kochanek S, Clemens PR, Mitani K, Chen HH, Chan S, Caskey CT. A new adenoviral vector - Replacement of all viral coding sequences with 28 kb of DNA independently expressing both full-length dystrophin and beta-galactosidase. Proc Natl Acad Sci U S A 1996; 93: 5731-5736.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 5731-5736
-
-
Kochanek, S.1
Clemens, P.R.2
Mitani, K.3
Chen, H.H.4
Chan, S.5
Caskey, C.T.6
-
11
-
-
0029857641
-
In vivo muscle gene transfer of full-length dystrophin with an adenoviral vector that lacks all viral genes
-
Clemens PR, Kochanek S, Sunada Y, et al. In vivo muscle gene transfer of full-length dystrophin with an adenoviral vector that lacks all viral genes. Gene Ther 1996; 3: 965-972.
-
(1996)
Gene Ther
, vol.3
, pp. 965-972
-
-
Clemens, P.R.1
Kochanek, S.2
Sunada, Y.3
-
12
-
-
0031049699
-
Persistence in muscle of an adenoviral vector that lacks all viral genes
-
Chen HH, Mack LM, Kelly R, Ontell M, Kochanek S, Clemens PR. Persistence in muscle of an adenoviral vector that lacks all viral genes. Proc Natl Acad Sci U S A 1997; 94: 1645-1650.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 1645-1650
-
-
Chen, H.H.1
Mack, L.M.2
Kelly, R.3
Ontell, M.4
Kochanek, S.5
Clemens, P.R.6
-
13
-
-
0030016358
-
Encapsidated adenovirus minichromosomes allow delivery and expression of a 14 kb dystrophin cDNA to muscle cells
-
Kumar-Singh R, Chamberlain JS. Encapsidated adenovirus minichromosomes allow delivery and expression of a 14 kb dystrophin cDNA to muscle cells. Hum Mol Genet 1996; 5: 913-921.
-
(1996)
Hum Mol Genet
, vol.5
, pp. 913-921
-
-
Kumar-Singh, R.1
Chamberlain, J.S.2
-
14
-
-
0029861452
-
Recombinant adenoviruses with large deletions generated by cre-mediated excision exhibit different biological properties compared with first-generation vectors in vitro and in vivo
-
Lieber A, He CY, Kirillova I, Kay MA. Recombinant adenoviruses with large deletions generated by cre-mediated excision exhibit different biological properties compared with first-generation vectors in vitro and in vivo. J Virol 1996; 70: 8944-8960.
-
(1996)
J Virol
, vol.70
, pp. 8944-8960
-
-
Lieber, A.1
He, C.Y.2
Kirillova, I.3
Kay, M.A.4
-
15
-
-
0030462599
-
A helper-dependent adenovirus vector system - Removal of helper virus by cre-mediated excision of the viral packaging signal
-
Parks RJ, Chen L, Anton M, Sankar U, Rudnicki MA, Graham FL. A helper-dependent adenovirus vector system - Removal of helper virus by cre-mediated excision of the viral packaging signal. Proc Natl Acad Sci U S A 1996; 93: 13565-13570.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 13565-13570
-
-
Parks, R.J.1
Chen, L.2
Anton, M.3
Sankar, U.4
Rudnicki, M.A.5
Graham, F.L.6
-
16
-
-
12944315064
-
Optimization of the helper-dependent adenovirus system for production and potency in vivo
-
Sandig V, Youil R, Bett A, et al. Optimization of the helper-dependent adenovirus system for production and potency in vivo. Proc Natl Acad Sci U S A 2000; 97: 1002-1007.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 1002-1007
-
-
Sandig, V.1
Youil, R.2
Bett, A.3
-
17
-
-
0031452056
-
Adenoviral preterminal protein stabilizes mini-adenoviral genomes in vitro and in vivo
-
Lieber A, He CY, Kay MA. Adenoviral preterminal protein stabilizes mini-adenoviral genomes in vitro and in vivo. Nat Biotechnol 1997; 15: 1383-1387.
-
(1997)
Nat Biotechnol
, vol.15
, pp. 1383-1387
-
-
Lieber, A.1
He, C.Y.2
Kay, M.A.3
-
18
-
-
0029843063
-
Development of a complementing cell line and a system for construction of adenovirus vectors with E1 and E2a deleted
-
Zhou H, O'Neal W, Morral N, Beaudet AL. Development of a complementing cell line and a system for construction of adenovirus vectors with E1 and E2a deleted. J Virol 1996; 70[10]: 7030-7038.
-
(1996)
J Virol
, vol.70
, Issue.10
, pp. 7030-7038
-
-
Zhou, H.1
O'Neal, W.2
Morral, N.3
Beaudet, A.L.4
-
19
-
-
0033540652
-
Persistence of an [E1-, polymerase-] adenovirus vector despite transduction of a neoantigen into immune-competent mice
-
Hu H, Serra D, Amalfitano A. Persistence of an [E1-, polymerase-] adenovirus vector despite transduction of a neoantigen into immune-competent mice. Hum Gene Ther 1999; 10: 355-364.
-
(1999)
Hum Gene Ther
, vol.10
, pp. 355-364
-
-
Hu, H.1
Serra, D.2
Amalfitano, A.3
-
20
-
-
0032991720
-
Generation of an adenovirus vector lacking E1, E2a, E3, and all of E4 except open reading frame 3
-
Gorziglia MI, Lapcevich C, Roy S, et al. Generation of an adenovirus vector lacking E1, E2a, E3, and all of E4 except open reading frame 3. J Virol 1999; 73: 6048-6055.
-
(1999)
J Virol
, vol.73
, pp. 6048-6055
-
-
Gorziglia, M.I.1
Lapcevich, C.2
Roy, S.3
-
21
-
-
0029959867
-
Biology of adenovirus vectors with E1 and E4 deletions for liver-directed gene therapy
-
Gao GP, Yang YP, Wilson JM. Biology of adenovirus vectors with E1 and E4 deletions for liver-directed gene therapy. J Virol 1996; 70: 8934-8943.
-
(1996)
J Virol
, vol.70
, pp. 8934-8943
-
-
Gao, G.P.1
Yang, Y.P.2
Wilson, J.M.3
-
22
-
-
0030923808
-
Long-term gene delivery into the livers of immunocompetent mice with E1/E4-defective adenoviruses
-
Dedieu JF, Vigne E, Torrent C, et al. Long-term gene delivery into the livers of immunocompetent mice with E1/E4-defective adenoviruses. J Virol 1997; 71: 4626-4637.
-
(1997)
J Virol
, vol.71
, pp. 4626-4637
-
-
Dedieu, J.F.1
Vigne, E.2
Torrent, C.3
-
23
-
-
0031008929
-
Persistent transgene expression in mouse liver following in vivo gene transfer with a delta-E1/delta-E4 adenovirus vector
-
Wang Q, Greenburg G, Bunch D, Farson D, Finer MH. Persistent transgene expression in mouse liver following in vivo gene transfer with a delta-E1/delta-E4 adenovirus vector. Gene Ther 1997; 4: 393-400.
-
(1997)
Gene Ther
, vol.4
, pp. 393-400
-
-
Wang, Q.1
Greenburg, G.2
Bunch, D.3
Farson, D.4
Finer, M.H.5
-
24
-
-
0029918572
-
Improved adenovirus packaging cell lines to support the growth of replication-defective gene-delivery vectors
-
Amalfitano A, Begy CR, Chamberlain JS. Improved adenovirus packaging cell lines to support the growth of replication-defective gene-delivery vectors. Proc Natl Acad Sci U S A 1996; 93: 3352-3356.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 3352-3356
-
-
Amalfitano, A.1
Begy, C.R.2
Chamberlain, J.S.3
-
25
-
-
0031883829
-
Production and characterization of improved adenovirus vectors with the E1, E2b, and E3 genes deleted
-
Amalfitano A, Hauser MA, Hu H, Serra D, Begy CR, Chamberlain JS. Production and characterization of improved adenovirus vectors with the E1, E2b, and E3 genes deleted. J Virol 1998; 72: 926-933.
-
(1998)
J Virol
, vol.72
, pp. 926-933
-
-
Amalfitano, A.1
Hauser, M.A.2
Hu, H.3
Serra, D.4
Begy, C.R.5
Chamberlain, J.S.6
-
26
-
-
0033540652
-
Persistence of an [E1(-), polymeraseC-] adenovirus vector despite transduction of a neoantigen into immune-competent mice
-
Hu HM, Serra D, Amalfitano A. Persistence of an [E1(-), polymeraseC-)] adenovirus vector despite transduction of a neoantigen into immune-competent mice. Hum Gene Ther 1999; 10: 355-364.
-
(1999)
Hum Gene Ther
, vol.10
, pp. 355-364
-
-
Hu, H.M.1
Serra, D.2
Amalfitano, A.3
-
27
-
-
2642673611
-
Reactivation of the previously silenced cytomegalovirus major immediate-early promoter in the mouse liver - Involvement of NF-K-B
-
Loser P, Jennings GS, Strauss M, Sandig V. Reactivation of the previously silenced cytomegalovirus major immediate-early promoter in the mouse liver - involvement of NF-K-B. J Virol 1998; 72: 180-190.
-
(1998)
J Virol
, vol.72
, pp. 180-190
-
-
Loser, P.1
Jennings, G.S.2
Strauss, M.3
Sandig, V.4
-
28
-
-
0032904969
-
A replication-incompetent adenovirus vector with the preterminal protein gene deleted efficiently transduces mouse ears
-
Moorhead JW, Clayton GH, Smith RL, Schaack J. A replication-incompetent adenovirus vector with the preterminal protein gene deleted efficiently transduces mouse ears. J Virol 1999; 73: 1046-1053.
-
(1999)
J Virol
, vol.73
, pp. 1046-1053
-
-
Moorhead, J.W.1
Clayton, G.H.2
Smith, R.L.3
Schaack, J.4
-
29
-
-
0030669598
-
Long-term erythropoietin expression in rodents and non-human primates following intramuscular injection of a replication-defective adenoviral vector
-
Svensson EC, Black HB, Dugger DL, et al. Long-term erythropoietin expression in rodents and non-human primates following intramuscular injection of a replication-defective adenoviral vector. Hum Gene Ther 1997; 8: 1797-1806.
-
(1997)
Hum Gene Ther
, vol.8
, pp. 1797-1806
-
-
Svensson, E.C.1
Black, H.B.2
Dugger, D.L.3
-
30
-
-
0029936764
-
Immune responses to transgene-encoded proteins limit the stability of gene expression after injection of replication-defective adenovirus vectors
-
Tripathy SK, Black HB, Goldwasser E, Leiden JM. Immune responses to transgene-encoded proteins limit the stability of gene expression after injection of replication-defective adenovirus vectors. Nat Med 1996; 2: 545-550.
-
(1996)
Nat Med
, vol.2
, pp. 545-550
-
-
Tripathy, S.K.1
Black, H.B.2
Goldwasser, E.3
Leiden, J.M.4
-
31
-
-
0032062510
-
Functional rescue of the sarcoglycan complex in the bio 14.6 Hamster using delta-sarcoglycan gene transfer
-
Holt KH, Lim LE, Straub V, et al. Functional rescue of the sarcoglycan complex in the bio 14.6 Hamster using delta-sarcoglycan gene transfer. Mol Cell 1998; 1: 841-848.
-
(1998)
Mol Cell
, vol.1
, pp. 841-848
-
-
Holt, K.H.1
Lim, L.E.2
Straub, V.3
-
32
-
-
0029834562
-
Evaluation of promoter strength for hepatic gene expression in vivo following adenovirus-mediated gene transfer
-
Guo ZS, Wang LH, Eisensmith RC, Woo SL. Evaluation of promoter strength for hepatic gene expression in vivo following adenovirus-mediated gene transfer. Gene Ther 1996; 3: 802-810.
-
(1996)
Gene Ther
, vol.3
, pp. 802-810
-
-
Guo, Z.S.1
Wang, L.H.2
Eisensmith, R.C.3
Woo, S.L.4
-
33
-
-
0029988465
-
Effective treatment of familial hypercholesterolaemia in the mouse model using adenovirus-mediated transfer of the VLDL receptor gene
-
Kozarsky KF, Jooss K, Donahee M, Strauss JF, Wilson JM. Effective treatment of familial hypercholesterolaemia in the mouse model using adenovirus-mediated transfer of the VLDL receptor gene. Nat Genet 1996; 13: 54-62.
-
(1996)
Nat Genet
, vol.13
, pp. 54-62
-
-
Kozarsky, K.F.1
Jooss, K.2
Donahee, M.3
Strauss, J.F.4
Wilson, J.M.5
-
34
-
-
0030999469
-
Adenovirus-mediated gene transfer - Influence of transgene, mouse strain and type of immune response on persistence of transgene expression
-
Michou AI, Santoro L, Christ M, Julliard V, Pavirani A, Mehtali M. Adenovirus-mediated gene transfer - Influence of transgene, mouse strain and type of immune response on persistence of transgene expression. Gene Ther 1997; 4: 473-482.
-
(1997)
Gene Ther
, vol.4
, pp. 473-482
-
-
Michou, A.I.1
Santoro, L.2
Christ, M.3
Julliard, V.4
Pavirani, A.5
Mehtali, M.6
-
35
-
-
3543030401
-
Adenovirus-mediated persistent cystic fibrosis transmembrane conductance regulator expression in mouse airway epithelium
-
Scaria A, St George JA, Jiang C, Kaplan JM, Wadsworth SC, Gregory RJ. Adenovirus-mediated persistent cystic fibrosis transmembrane conductance regulator expression in mouse airway epithelium. J Virol 1998; 72: 7302-7309.
-
(1998)
J Virol
, vol.72
, pp. 7302-7309
-
-
Scaria, A.1
St George, J.A.2
Jiang, C.3
Kaplan, J.M.4
Wadsworth, S.C.5
Gregory, R.J.6
-
36
-
-
0028914687
-
Strain related variations in adenovirally mediated transgene expression from mouse hepatocytes in vivo: Comparisons between immunocompetent and immunodeficient inbred strains
-
Barr D, Tubb J, Ferguson D, et al. Strain related variations in adenovirally mediated transgene expression from mouse hepatocytes in vivo: Comparisons between immunocompetent and immunodeficient inbred strains. Gene Ther 1995; 2: 151-155.
-
(1995)
Gene Ther
, vol.2
, pp. 151-155
-
-
Barr, D.1
Tubb, J.2
Ferguson, D.3
-
37
-
-
0028937785
-
Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses
-
Yang Y, Li Q, Ertl HC, Wilson JM. Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses. J Virol 1995; 69: 2004-2015.
-
(1995)
J Virol
, vol.69
, pp. 2004-2015
-
-
Yang, Y.1
Li, Q.2
Ertl, H.C.3
Wilson, J.M.4
-
38
-
-
0029028989
-
Clearance of adenovirus-infected hepatocytes by MHC class I- restricted CD4+ CTLs in vivo
-
Yang Y, Wilson JM. Clearance of adenovirus-infected hepatocytes by MHC class I-restricted CD4+ CTLs in vivo. J Immunol 1995; 155: 2564-2570.
-
(1995)
J Immunol
, vol.155
, pp. 2564-2570
-
-
Yang, Y.1
Wilson, J.M.2
-
39
-
-
0028328261
-
Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy
-
Yang Y, Nunes FA, Berencsi K, Furth EE, Gonczol E, Wilson JM. Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy. Proc Natl Acad Sci U S A 1994; 91: 4407-4411.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 4407-4411
-
-
Yang, Y.1
Nunes, F.A.2
Berencsi, K.3
Furth, E.E.4
Gonczol, E.5
Wilson, J.M.6
-
40
-
-
0028832360
-
Transient expression of genes transferred in vivo into heart using first-generation adenoviral vectors - Role of the immune response
-
Gilgenkrantz H, Duboc D, Juillard V, et al. Transient expression of genes transferred in vivo into heart using first-generation adenoviral vectors - Role of the immune response. Hum Gene Ther 1995; 6: 1265-1274.
-
(1995)
Hum Gene Ther
, vol.6
, pp. 1265-1274
-
-
Gilgenkrantz, H.1
Duboc, D.2
Juillard, V.3
-
41
-
-
0030728433
-
Activation of transgene expression by early region 4 is responsible for a high level of persistent transgene expression from adenovirus vectors in vivo
-
Brough DE, Hsu C, Kulesa VA, et al. Activation of transgene expression by early region 4 is responsible for a high level of persistent transgene expression from adenovirus vectors in vivo. J Virol 1997; 71: 9206-9213.
-
(1997)
J Virol
, vol.71
, pp. 9206-9213
-
-
Brough, D.E.1
Hsu, C.2
Kulesa, V.A.3
-
42
-
-
0029836503
-
Role of viral antigens in destructive cellular immune responses to adenovirus vector-transduced cells in mouse lungs
-
Yang Y, Su Q, Wilson JM. Role of viral antigens in destructive cellular immune responses to adenovirus vector-transduced cells in mouse lungs. J Virol 1996; 70: 7209-7212.
-
(1996)
J Virol
, vol.70
, pp. 7209-7212
-
-
Yang, Y.1
Su, Q.2
Wilson, J.M.3
-
43
-
-
0031916435
-
Genomic DNA transfer with a high-capacity adenovirus vector results in improved in vivo gene expression and decreased toxicity
-
Schiedner G, Morral N, Parks RJ, et al. Genomic DNA transfer with a high-capacity adenovirus vector results in improved in vivo gene expression and decreased toxicity. Nat Genet 1998; 18: 180-183.
-
(1998)
Nat Genet
, vol.18
, pp. 180-183
-
-
Schiedner, G.1
Morral, N.2
Parks, R.J.3
-
44
-
-
13144283616
-
An adenoviral vector deleted for all viral coding sequences results in enhanced safety and extended expression of a leptin transgene
-
Morsy MA, Gu MC, Motzel S, et al. An adenoviral vector deleted for all viral coding sequences results in enhanced safety and extended expression of a leptin transgene. Proc Nat Acad Sci U S A 1998; 95: 7866-7871.
-
(1998)
Proc Nat Acad Sci U S A
, vol.95
, pp. 7866-7871
-
-
Morsy, M.A.1
Gu, M.C.2
Motzel, S.3
-
45
-
-
0032816327
-
Improved production of gutted adenovirus in cells expressing adenovirus preterminal protein and DNA polymerase
-
Hartigan-O'Connor D, Amalfitano A, Chamberlain JS. Improved production of gutted adenovirus in cells expressing adenovirus preterminal protein and DNA polymerase. J Virol 1999; 73: 7835-7841.
-
(1999)
J Virol
, vol.73
, pp. 7835-7841
-
-
Hartigan-O'Connor, D.1
Amalfitano, A.2
Chamberlain, J.S.3
|