-
2
-
-
0028921477
-
Interleukin-6 in human multiple myeloma
-
Klein B, Zhang X, Lu Z, Bataille R. Interleukin-6 in human multiple myeloma. Blood. 1995;85:863-872.
-
(1995)
Blood
, vol.85
, pp. 863-872
-
-
Klein, B.1
Zhang, X.2
Lu, Z.3
Bataille, R.4
-
3
-
-
0025642960
-
Suppression of programmed death and G1 arrest in B-cell hybridomas by interleukin-6 is not accompanied by altered gene expression of immediate early response genes
-
Sabourin LA, Hawley RG. Suppression of programmed death and G1 arrest in B-cell hybridomas by interleukin-6 is not accompanied by altered gene expression of immediate early response genes. J Cell Physiol. 1990;145:564-574.
-
(1990)
J Cell Physiol
, vol.145
, pp. 564-574
-
-
Sabourin, L.A.1
Hawley, R.G.2
-
4
-
-
0023849455
-
Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas
-
Kawano M, Hirano T, Matsuda T, et al. Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas. Nature. 1988;332:83-85.
-
(1988)
Nature
, vol.332
, pp. 83-85
-
-
Kawano, M.1
Hirano, T.2
Matsuda, T.3
-
5
-
-
0031036356
-
Interferon-β interrupts interleukin-6-dependent signaling events in myeloma cells
-
Berger LC, Hawley RG. Interferon-β interrupts interleukin-6-dependent signaling events in myeloma cells. Blood. 1997;89:261-271.
-
(1997)
Blood
, vol.89
, pp. 261-271
-
-
Berger, L.C.1
Hawley, R.G.2
-
6
-
-
0030292721
-
Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: Involvement of STAT3 in anti-apoptosis
-
Fukada T, Hibi M, Yamanaka Y, et al. Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: involvement of STAT3 in anti-apoptosis. Immunity. 1996;5:449-460.
-
(1996)
Immunity
, vol.5
, pp. 449-460
-
-
Fukada, T.1
Hibi, M.2
Yamanaka, Y.3
-
7
-
-
0031225483
-
IL-6 triggers cell growth via the ras-dependent mitogen-activated protein kinase cascade
-
Ogata A, Chauhan D, Teoh G, et al. IL-6 triggers cell growth via the ras-dependent mitogen-activated protein kinase cascade. J Immunol. 1997; 159:2212-2221.
-
(1997)
J Immunol
, vol.159
, pp. 2212-2221
-
-
Ogata, A.1
Chauhan, D.2
Teoh, G.3
-
8
-
-
0029002318
-
Prevention of myeloma cell apoptosis by ectopic bcl-2 expression or interleukin 6-mediated up-regulation of bcl-xL
-
Schwarze MMK, Hawley RG. Prevention of myeloma cell apoptosis by ectopic bcl-2 expression or interleukin 6-mediated up-regulation of bcl-xL. Cancer Res. 1995;55:2262-2265.
-
(1995)
Cancer Res
, vol.55
, pp. 2262-2265
-
-
Schwarze, M.M.K.1
Hawley, R.G.2
-
9
-
-
0032125757
-
Interleukin-6-induced inhibition of multiple myeloma cell apoptosis: Support for the hypothesis that protection is mediated via inhibition of the JNK/SAPK pathway
-
Xu F, Sharma S, Gardner A, et al. Interleukin-6-induced inhibition of multiple myeloma cell apoptosis: support for the hypothesis that protection is mediated via inhibition of the JNK/SAPK pathway. Blood. 1998;92:241-251.
-
(1998)
Blood
, vol.92
, pp. 241-251
-
-
Xu, F.1
Sharma, S.2
Gardner, A.3
-
10
-
-
0030464093
-
Promiscuous translocations into immunoglobulin heavy chain switch regions in multiple myeloma
-
Bergsagel PL, Chesi M, Nardini E, Brents LA, Kirby SL, Kuehl WM. Promiscuous translocations into immunoglobulin heavy chain switch regions in multiple myeloma. Proc Natl Sci Acad U S A. 1996;93:13,931-13,936.
-
(1996)
Proc Natl Sci Acad U S A
, vol.93
-
-
Bergsagel, P.L.1
Chesi, M.2
Nardini, E.3
Brents, L.A.4
Kirby, S.L.5
Kuehl, W.M.6
-
11
-
-
84984756503
-
Deregulation of MUM1/IRF4 by chromosomal translocation in multiple myeloma
-
Iida S, Rao PH, Butler M, et al. Deregulation of MUM1/IRF4 by chromosomal translocation in multiple myeloma. Nat Genet. 1997;17:226-230.
-
(1997)
Nat Genet
, vol.17
, pp. 226-230
-
-
Iida, S.1
Rao, P.H.2
Butler, M.3
-
12
-
-
0029978550
-
Dysregulation of cyclin D1 by translocation into an IgH gamma switch region in two multiple myeloma cell lines
-
Chesi M, Bergsagel PL, Brants LA, Smith CM, Gerhard DS, Kuehl WM. Dysregulation of cyclin D1 by translocation into an IgH gamma switch region in two multiple myeloma cell lines. Blood. 1996;88:674-681.
-
(1996)
Blood
, vol.88
, pp. 674-681
-
-
Chesi, M.1
Bergsagel, P.L.2
Brants, L.A.3
Smith, C.M.4
Gerhard, D.S.5
Kuehl, W.M.6
-
13
-
-
0031839633
-
Frequent dysregulation of the c-maf proto-oncogene at 16q23 by translocation to an Ig locus in multiple myeloma
-
Chesi M, Bergsagel PL, Shonukan OO, et al. Frequent dysregulation of the c-maf proto-oncogene at 16q23 by translocation to an Ig locus in multiple myeloma. Blood. 1998;91:4457-4463.
-
(1998)
Blood
, vol.91
, pp. 4457-4463
-
-
Chesi, M.1
Bergsagel, P.L.2
Shonukan, O.O.3
-
14
-
-
0030922231
-
Frequent translocalion t(4;14)(p16.3;q32.3) in multiple myeloma is associated with increased expression and activating mutations of fibroblast growth factor receptor 3
-
Chesi M, Nardini E, Brents LA, et al. Frequent translocalion t(4;14)(p16.3;q32.3) in multiple myeloma is associated with increased expression and activating mutations of fibroblast growth factor receptor 3. Nat Genet. 1997;16:260-264.
-
(1997)
Nat Genet
, vol.16
, pp. 260-264
-
-
Chesi, M.1
Nardini, E.2
Brents, L.A.3
-
15
-
-
0343355828
-
High incidence of translocations t(11;14)(q13;q32) and t(4;14)(p16;q32) in patients with plasma cell malignancies
-
Avet-Loiseau H, Li JY, Facon T, et al. High incidence of translocations t(11;14)(q13;q32) and t(4;14)(p16;q32) in patients with plasma cell malignancies. Cancer Res. 1998;58:5640-5645.
-
(1998)
Cancer Res
, vol.58
, pp. 5640-5645
-
-
Avet-Loiseau, H.1
Li, J.Y.2
Facon, T.3
-
16
-
-
0032402134
-
Identification of new nonrandom translocations in multiple myeloma with multicolor spectral karyotyping
-
Sawyer JR, Lukacs JL, Munshi N, et al. Identification of new nonrandom translocations in multiple myeloma with multicolor spectral karyotyping. Blood. 1998;92:4269-4278.
-
(1998)
Blood
, vol.92
, pp. 4269-4278
-
-
Sawyer, J.R.1
Lukacs, J.L.2
Munshi, N.3
-
17
-
-
0030792866
-
The Ig heavy chain gene is frequently involved in chromosomal translocations in multiple myeloma and plasma cell leukemia as detected by in situ hybridization
-
Nishida K, Tamura A, Nakazawa N, et al. The Ig heavy chain gene is frequently involved in chromosomal translocations in multiple myeloma and plasma cell leukemia as detected by in situ hybridization. Blood. 1997;90:526-534.
-
(1997)
Blood
, vol.90
, pp. 526-534
-
-
Nishida, K.1
Tamura, A.2
Nakazawa, N.3
-
18
-
-
0032212243
-
The t(4;14) translocation in myeloma dysregulates both FGFR3 and a novel gene, MMSET, resulting in IgH/MMSET hybrid transcripts
-
Chesi M, Nardini E, Lin RSC, Smith KD, Kuehl WM, Bergsagel PL. The t(4;14) translocation in myeloma dysregulates both FGFR3 and a novel gene, MMSET, resulting in IgH/MMSET hybrid transcripts. Blood. 1998;92:3025-3034.
-
(1998)
Blood
, vol.92
, pp. 3025-3034
-
-
Chesi, M.1
Nardini, E.2
Lin, R.S.C.3
Smith, K.D.4
Kuehl, W.M.5
Bergsagel, P.L.6
-
19
-
-
0029917507
-
Fibroblast growth factor receptor 3 is a negative regulator of bone growth
-
Deng C, Wynshaw-Boris A, Zhou F, Kuo A, Leder P. Fibroblast growth factor receptor 3 is a negative regulator of bone growth. Cell. 1996;84:911-921.
-
(1996)
Cell
, vol.84
, pp. 911-921
-
-
Deng, C.1
Wynshaw-Boris, A.2
Zhou, F.3
Kuo, A.4
Leder, P.5
-
20
-
-
0029928791
-
Skeletal overgrowth and deafness in mice lacking fibroblast growth factor receptor 3
-
Colvin JS, Bohne BA, Harding GW, McEwan DG, Ornitz DM. Skeletal overgrowth and deafness in mice lacking fibroblast growth factor receptor 3. Nat Genet. 1996;12:390-397.
-
(1996)
Nat Genet
, vol.12
, pp. 390-397
-
-
Colvin, J.S.1
Bohne, B.A.2
Harding, G.W.3
McEwan, D.G.4
Ornitz, D.M.5
-
21
-
-
0028872752
-
Thanatophoric dysplasia (types I and II) caused by distinct mutations in fibroblast growth factor receptor 3
-
Tavormina PL, Shiang R, Thompson LM, et al. Thanatophoric dysplasia (types I and II) caused by distinct mutations in fibroblast growth factor receptor 3. Nat Genet. 1995;9:321-328.
-
(1995)
Nat Genet
, vol.9
, pp. 321-328
-
-
Tavormina, P.L.1
Shiang, R.2
Thompson, L.M.3
-
22
-
-
0029912958
-
Common mutations in the fibroblast growth factor receptor 3 (FGFR 3) gene account for achondroplasia, hypochondroplasia, and thanatophoric dwarfism
-
Bonaventure J, Rousseau F, Legeai-Mallet L, Le Merrer M, Munnich A, Maroteaux P. Common mutations in the fibroblast growth factor receptor 3 (FGFR 3) gene account for achondroplasia, hypochondroplasia, and thanatophoric dwarfism. Am J Med Genet. 1996;63:148-154.
-
(1996)
Am J Med Genet
, vol.63
, pp. 148-154
-
-
Bonaventure, J.1
Rousseau, F.2
Legeai-Mallet, L.3
Le Merrer, M.4
Munnich, A.5
Maroteaux, P.6
-
23
-
-
0029935895
-
Graded activation of fibroblast growth factor receptor 3 by mutations causing achondroplasia and thanatophoric dysplasia
-
Naski MC, Wang Q, Xu J, Ornitz DM. Graded activation of fibroblast growth factor receptor 3 by mutations causing achondroplasia and thanatophoric dysplasia. Nat Genet. 1996;13:233-237.
-
(1996)
Nat Genet
, vol.13
, pp. 233-237
-
-
Naski, M.C.1
Wang, Q.2
Xu, J.3
Ornitz, D.M.4
-
24
-
-
0029945085
-
Profound ligand-independent kinase activation of fibroblast growth factor receptor 3 by the activation loop mutation responsible for a lethal skeletal dysplasia, thanatophoric dysplasia type II
-
Webster MK, D'Avis PY, Robertson SC, Donoghue DJ. Profound ligand-independent kinase activation of fibroblast growth factor receptor 3 by the activation loop mutation responsible for a lethal skeletal dysplasia, thanatophoric dysplasia type II. Mol Cell Biol. 1996;16:4081-4087.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 4081-4087
-
-
Webster, M.K.1
D'Avis, P.Y.2
Robertson, S.C.3
Donoghue, D.J.4
-
25
-
-
0030896404
-
Activation of Stat1 by mutant fibroblast growth-factor receptor in thanatophoric dysplasia type II dwarfism
-
Su WS, Kitagawa M, Xue N, et al. Activation of Stat1 by mutant fibroblast growth-factor receptor in thanatophoric dysplasia type II dwarfism. Nature. 1997;386:288-292.
-
(1997)
Nature
, vol.386
, pp. 288-292
-
-
Su, W.S.1
Kitagawa, M.2
Xue, N.3
-
26
-
-
0032557555
-
Fibroblast growth factor receptor 3 mutations promote apoptosis but do not alter chondrocyta proliferation in thanatophoric dysplasia
-
Legeai-Mallet L, Benoist-Lasselin C, Delezoide A, Munnich A, Bonaventure J. Fibroblast growth factor receptor 3 mutations promote apoptosis but do not alter chondrocyta proliferation in thanatophoric dysplasia. J Biol Chem. 1998;273:13,007-13,014.
-
(1998)
J Biol Chem
, vol.273
-
-
Legeai-Mallet, L.1
Benoist-Lasselin, C.2
Delezoide, A.3
Munnich, A.4
Bonaventure, J.5
-
27
-
-
0030912739
-
Signals through gp130 upregulate bcl-x gene expression via STAT1-binding cis-element in cardiac myocytes
-
Fujio Y, Kunisada K, Hirota H, Yamauchi-Takihara K, Kishimoto T. Signals through gp130 upregulate bcl-x gene expression via STAT1-binding cis-element in cardiac myocytes. J Clin Invest. 1997;99: 2898-2905.
-
(1997)
J Clin Invest
, vol.99
, pp. 2898-2905
-
-
Fujio, Y.1
Kunisada, K.2
Hirota, H.3
Yamauchi-Takihara, K.4
Kishimoto, T.5
-
28
-
-
0030448052
-
Retroviral vectors for production of interleukin-12 in the bone marrow to induce graft-verus-leukemia effect
-
Hawley RG, Lieu FHL, Fong AZC, Goldman SJ, Leonard JP, Hawley TS. Retroviral vectors for production of interleukin-12 in the bone marrow to induce graft-verus-leukemia effect. Ann N Y Acad Sci. 1996;795:341-345.
-
(1996)
Ann N Y Acad Sci
, vol.795
, pp. 341-345
-
-
Hawley, R.G.1
Lieu, F.H.L.2
Fong, A.Z.C.3
Goldman, S.J.4
Leonard, J.P.5
Hawley, T.S.6
-
29
-
-
0022767368
-
Redesign of retrovirus packaging cell lines to avoid recombination leading to helper virus production
-
Miller AD, Buttimore C. Redesign of retrovirus packaging cell lines to avoid recombination leading to helper virus production. Mol Cell Biol. 1986; 6:2895-2902.
-
(1986)
Mol Cell Biol
, vol.6
, pp. 2895-2902
-
-
Miller, A.D.1
Buttimore, C.2
-
30
-
-
0023871422
-
A safe packaging line for gene transfer: Separating viral genes on two different plasmids
-
Markowitz D, Goff S, Bank A. A safe packaging line for gene transfer: separating viral genes on two different plasmids. J Virol. 1988;62:1120-1124.
-
(1988)
J Virol
, vol.62
, pp. 1120-1124
-
-
Markowitz, D.1
Goff, S.2
Bank, A.3
-
31
-
-
0026597736
-
Increased frequency of both total and specific monoclonal antibody producing hybridomas using a fusion partner that constitutively expresses recombinant IL-6
-
Harris JF, Hawley RG, Hawley TS, Crawford-Sharpe GC. Increased frequency of both total and specific monoclonal antibody producing hybridomas using a fusion partner that constitutively expresses recombinant IL-6. J Immunol Methods. 1992;148:199-207.
-
(1992)
J Immunol Methods
, vol.148
, pp. 199-207
-
-
Harris, J.F.1
Hawley, R.G.2
Hawley, T.S.3
Crawford-Sharpe, G.C.4
-
32
-
-
0028986902
-
pp60c-src expression is induced by activation of normal human T lymphocytes
-
Branch DR, Mills GB. pp60c-src expression is induced by activation of normal human T lymphocytes. J Immunol. 1995;154:3678-3685.
-
(1995)
J Immunol
, vol.154
, pp. 3678-3685
-
-
Branch, D.R.1
Mills, G.B.2
-
33
-
-
0344517071
-
Fusion of the ets transcription factor TEL to Jak2 results in constitutive Jak-Stat signaling
-
Ho JMY, Beattie BK, Squire JA, Frank DA, Barber DL. Fusion of the ets transcription factor TEL to Jak2 results in constitutive Jak-Stat signaling. Blood. 1999;12:4354-4364.
-
(1999)
Blood
, vol.12
, pp. 4354-4364
-
-
Ho, J.M.Y.1
Beattie, B.K.2
Squire, J.A.3
Frank, D.A.4
Barber, D.L.5
-
34
-
-
0028097932
-
Tyrosine phosphorylated p91 binds to a single element in the ISGF2/IRF-1 promoter to mediate induction by IFN alpha and IFN gamma, and is likely to autoregulate the p91 gene
-
Pine R, Canova A, Schindler C. Tyrosine phosphorylated p91 binds to a single element in the ISGF2/IRF-1 promoter to mediate induction by IFN alpha and IFN gamma, and is likely to autoregulate the p91 gene. EMBO J. 1994;13:158-167.
-
(1994)
EMBO J
, vol.13
, pp. 158-167
-
-
Pine, R.1
Canova, A.2
Schindler, C.3
-
35
-
-
0030924350
-
JAK2 is required for induction of the murine DUB-1 gene
-
Jaster R, Zhu Y, Pless M, Bhattacharya S, Mathey-Prevot B, D'Andrea AD. JAK2 is required for induction of the murine DUB-1 gene. Mol Cell Biol. 1997;17:3364-3372.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 3364-3372
-
-
Jaster, R.1
Zhu, Y.2
Pless, M.3
Bhattacharya, S.4
Mathey-Prevot, B.5
D'Andrea, A.D.6
-
36
-
-
0032538801
-
STAT3 orchestrates contradictory signals in cytokine-induced G1 to S cell-cycle transition
-
Fukada T, Ohtani T, Yoshida Y, et al. STAT3 orchestrates contradictory signals in cytokine-induced G1 to S cell-cycle transition. EMBO J. 1998;17:6670-6677.
-
(1998)
EMBO J
, vol.17
, pp. 6670-6677
-
-
Fukada, T.1
Ohtani, T.2
Yoshida, Y.3
-
37
-
-
0032984589
-
Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells
-
Catlett-Falcone R, Landowski TH, Oshiro MM, et al. Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells. Immunity. 1999;10:105-115.
-
(1999)
Immunity
, vol.10
, pp. 105-115
-
-
Catlett-Falcone, R.1
Landowski, T.H.2
Oshiro, M.M.3
-
38
-
-
0032578721
-
STAT3 mediates the survival signal in oncogenic ras-transfected intestinal epithelial cells
-
Zushi S, Shinomura Y, Kiyohara T, et al. STAT3 mediates the survival signal in oncogenic ras-transfected intestinal epithelial cells. Int J Cancer. 1998;78:326-330.
-
(1998)
Int J Cancer
, vol.78
, pp. 326-330
-
-
Zushi, S.1
Shinomura, Y.2
Kiyohara, T.3
-
39
-
-
1842372689
-
Signal transduction pathway of human fibroblast growth factor receptor 3: Identification of a novel 66-kDa phosphoprotein
-
Kanai M, Goke M, Tsunekawa S, Podolsky DK. Signal transduction pathway of human fibroblast growth factor receptor 3: identification of a novel 66-kDa phosphoprotein. J Biol Chem. 1997;272: 6621-6628.
-
(1997)
J Biol Chem
, vol.272
, pp. 6621-6628
-
-
Kanai, M.1
Goke, M.2
Tsunekawa, S.3
Podolsky, D.K.4
-
40
-
-
0029790656
-
FGF and stress regulate CREB and ATF-1 via a pathway involving p38 MAP kinase and MAPKAP kinase-2
-
Tan Y, Rouse J, Zhang A, Cariati S, Cohen P, Comb MJ. FGF and stress regulate CREB and ATF-1 via a pathway involving p38 MAP kinase and MAPKAP kinase-2. EMBO J. 1996;15:4629-4642.
-
(1996)
EMBO J
, vol.15
, pp. 4629-4642
-
-
Tan, Y.1
Rouse, J.2
Zhang, A.3
Cariati, S.4
Cohen, P.5
Comb, M.J.6
-
41
-
-
0032532626
-
FGFR3 gene mutations associated with human skeletal disorders occur rarely in multiple myeloma
-
Fracchiolla NS, Luminari S, Baldini L, Lombard L, Maiolo AT, Neri A. FGFR3 gene mutations associated with human skeletal disorders occur rarely in multiple myeloma. Blood. 1998;92:2987-2989.
-
(1998)
Blood
, vol.92
, pp. 2987-2989
-
-
Fracchiolla, N.S.1
Luminari, S.2
Baldini, L.3
Lombard, L.4
Maiolo, A.T.5
Neri, A.6
|