High incidence of translocations t(11;14)(q13;q32) and t(4;14)(p16;q32) in patients with plasma cell malignancies

Cancer Research

Volumn 58, Issue 24, 1998, Pages 5640-5645

  Avet Loiseau, Hervé ^a,e   Li, Jian Yong ^a   Facon, Thierry ^b   Brigaudeau, Christophe ^c   Morineau, Nadine ^a   Maloisel, Frédéric ^d   Rapp, Marie José ^a   Talmant, Pascaline ^a   Trimoreau, Franck ^c   Jaccard, Arnaud ^c   Harousseau, Jean Luc ^a   Bataille, Régis ^a  

^a NANTES UNIVERSITY HOSPITAL   (France)

^b LILLE UNIVERSITY HOSPITAL   (France)

^c LIMOGES UNIVERSITY HOSPITAL   (France)

^d INSTITUT DE RECHERCHES INTERNATIONALES SERVIER   (France)

^e INSTITUT DE BIOLOGIE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BETA 2 MICROGLOBULIN; IMMUNOGLOBULIN; IMMUNOGLOBULIN SUBCLASS;

ARTICLE; CHROMOSOME TRANSLOCATION; CHROMOSOME TRANSLOCATION 11; CHROMOSOME TRANSLOCATION 4; CONTROLLED STUDY; FLUORESCENCE IN SITU HYBRIDIZATION; GENE REARRANGEMENT; HUMAN; HUMAN CELL; INCIDENCE; MAJOR CLINICAL STUDY; MULTIPLE MYELOMA; PLASMA CELL LEUKEMIA; PRIORITY JOURNAL; PROGNOSIS;

ANEUPLOIDY; CHROMOSOMES, HUMAN, PAIR 11; CHROMOSOMES, HUMAN, PAIR 14; CHROMOSOMES, HUMAN, PAIR 4; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; LEUKEMIA, PLASMACYTIC; MULTIPLE MYELOMA; PROGNOSIS; TRANSLOCATION, GENETIC;

EID: 0343355828     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Bergsagel, P. L., Chesi, M., Nardini, E., Brents, L. A., Kirby, S. L., and Kuehl, W. M. Promiscuous translocations into immunoglobulin heavy chain switch regions in multiple myeloma. Proc. Natl. Acad. Sci. USA, 93: 13931-13936, 1996.
2. Dewald, G. W., Kyle, R. A., Hicks, G. A., and Greipp, P. R. The clinical significance of cytogenetics studies in 100 patients with multiple myeloma, plasma cell leukemia or amyloidosis. Blood, 66: 380-390, 1985.
3. Could, J., Alexanian, R., Goodacre, A., Pathak, S., Hecht, B., and Barlogie, B. Plasma cell karyotype in multiple myeloma. Blood, 71: 453-456, 1988.
4. Nishida, K., Taniwaki, M., Misawa, S., and Abe, T. Nonrandom rearrangement of chromosome 14 at band 14q32.33 in human lymphoid malignancies with mature B-cell phenotype. Cancer Res., 49: 1275-1278, 1989.
5. Laï, J. L., Zandecki, M., Mary, J. Y., Bernardi, R., Izydorczyk, V., Flactif, M., Morel, P., Jouet, J. P., Bauters, F., and Facon, T. Improved cytogenetics in multiple myeloma: a study of 151 patients including 117 patients at diagnosis. Blood, 85: 2490-2497, 1995.
6. Sawyer, J. R., Waldron, J. A., Jagannath, S., and Barlogie, B. Cytogenetics findings in 200 patients with multiple myeloma. Cancer Genet. Cytogenet., 82: 41-49, 1995.
7. Calasanz, M. J., Cigudosa, J. C., Odero, M. D., Ferreira, C., Ardanaz, M. T., Fraile, A., Carrasco, J. L., Sole, F., Cuesta, B., and Gullon, A. Cytogenetic analysis of 280 patients with multiple myeloma and related disorder: primary breakpoints and clinical correlations. Genes Chromosomes Cancer, 18: 84-93, 1997.
8. Taniwaki, M., Nishida, K., Takashima, T., Nakagawa, H., Fujii, H., Tamaki, T., Shimazaki, C., Horiike, S., Misawa, S., Abe, T., and Kashima, K. Nonrandom chromosomal rearrangements of 14q32.3 and 19p13.3 and preferential deletion of 1p in 21 patients with multiple myeloma and plasma cell leukemia. Blood, 84: 2283-2290, 1994.
9. Smadja, N. V., Louvet, C., Isnard, F., Dutel, J. L., Grange, M. J., Varette, C., and Krulik, M. Cytogenetic study in multiple myeloma at diagnosis: comparison of two techniques. Br. J. Haematol., 90: 619-624, 1996.
10. Nishida, K., Tamura, A., Nakazawa, N., Ueda, Y., Abe, T., Matsuda, F., Kashima, K., and Taniwaki, M. The Ig heavy chain gene is frequently involved in chromosomal translocations in multiple myeloma and plasma cell leukemia as detected by in situ hybridization. Blood, 90: 526-534, 1997.
11. Chesi, M., Bergsagel, P. L., Brents, L. A., Smith, C. M., Gerhard, D. S., and Kuehl, W. M. Dysregulation of cyclin D1 by translocation into an IgH gamma switch region in two multiple myeloma cell lines. Blood, 88: 674-681, 1996.
12. Fold, M., Rettig, M., Munroe, D., Vescio, R., Hall, J., and Berenson, J. Expression of novel genes in human chromosomal locus 11q13. Blood, 90 (Suppl.): 317a, 1997.
13. Chesi, M., Nardini, E., Brents, L. A., Schrock, E., Ried, T., Kuehl, W. M., and Bergsagel, P. L. Frequent translocation t(4;14)(p16.3;q32.3) in multiple myeloma is associated with increased expression and activating mutations of fibroblast growth factor receptor 3. Nat. Genet., 16: 260-264, 1997.
14. Iida, S., Rao, P. H., Butler, M., Corradini, P., Boccadoro, M., Klein, B., Chagami, R. S. K., and Dalla-Pavera, R. Deregulation of MUM1/1RF4 by chromosomal translocation in multiple myeloma. Nat. Genet., 17: 226-230, 1997.
15. Chesi, M., Bergsagel, P. L., Shonukan, O. O., Martelli, M. L., Brents, L. A., Chen, T., Schrock, E., Ried, T., and Kuehl, W. M. Frequent dysregulation of the c-maf proto-oncogene at 16q23 by translocation to an Ig locus in multiple myeloma. Blood, 91: 4457-4463, 1998.
16. Richelda, R., Ronchetli, D., Baldini, L., Cro, L., Viggiano, L., Marzella, R., Rocchi, M., Oisuki, T., Lorabardi, L., Maiolo, A. T., and Neri, A. A novel chromosomal translocation t(4;14)(p16.3;q32) in multiple myeloma involves the fibroblast growth-factor receptor 3 gene. Blood, 90: 4062-4069, 1997.
17. Durie, B. G. M., and Salmon, S. E. Multiple myeloma, macroglobulinaemia and monoclonal gammopathies. In: A. V. Hoffbrand, M. C. Brain, and J. Hirsh (eds), Recent Advances in Haematology, pp. 243-261. New York: Churchill Livingstone, 1977.
18. Portier, M., Rajzbaum, G., Zhang, X. G., Altai, M., Rusalen, C., Wijdenes, J., Mannoni, P., Maraninchi, D., Piechaczyc, M., Bataille, R., and Klein, B. In vivo interleukin 6 expression in the tumoral environment in multiple myeloma. Eur. J. Immunol., 21: 1759-1764, 1991.
19. Zhang, X. G., Gaillard, J. P., Robillard, N., Lu, Z. Y., Gu, Z. J., Jourdan, M., Boiron, J. M., Bataille, R., and Klein, B. Reproducible obtaining of human myeloma cell lines as a model for tumor stem cell study in human multiple myeloma. Blood, 83: 3654-3659, 1994.
20. Avet-Loiseau, H., Garand, R., Gaillard, F., Daviet, A., Mellerin, M. P., Robillard, N., Bouyge, I., Arcot, S., Batzer, M., Talmant, P., Harousseau, J. L., Milpied, N., and Bataille, R. Detection of the t(11;14) using interphase molecular cytogenetics in mantle cell lymphoma and atypical chronic lymphocytic leukemia. Genes Chromosomes Cancer, 23: 175-182, 1998.
21. Tricot, G., Barlogie, B., Jagannath, S., Bracy, D., Mattox, S., Vesole, D. H., Naucke, S., and Sawyer, J. R. Poor prognosis in multiple myeloma is associated only with partial or complete deletions of chromosome 13 or abnormalities involving 11q and not with other karyotype abnormalities. Blood, 86: 4250-4258, 1995.
22. Brigaudeau, C., Trimoreau, F., Gachard, N., Rouzier, E., Jaccard, A., Bordessoule, D., and Praloran, V. Cytogenetic study of 30 patients with multiple myeloma: comparison of 3 and 6 day bone marrow cultures stimulated or not with eytokines by using a miniaturized karyotypic method. Br. J. Haematol. 96: 594-600, 1997.