-
1
-
-
0030892283
-
Cytotoxic T cells and viral hepatitis
-
Chisari F.V. Cytotoxic T cells and viral hepatitis. J Clin Invest. 99:1997;1472-1477.
-
(1997)
J Clin Invest
, vol.99
, pp. 1472-1477
-
-
Chisari, F.V.1
-
2
-
-
0031308730
-
The role of immune responses in the pathogenesis of hepatitis C virus infection
-
Koziel M. The role of immune responses in the pathogenesis of hepatitis C virus infection. J Viral Hepat. 4:1997;31-41.
-
(1997)
J Viral Hepat
, vol.4
, pp. 31-41
-
-
Koziel, M.1
-
3
-
-
0028916425
-
Hepatitis B virus immunopathogenesis
-
Chisari F.V., Ferrari C. Hepatitis B virus immunopathogenesis. Annu Rev Immunol. 13:1995;29-60.
-
(1995)
Annu Rev Immunol
, vol.13
, pp. 29-60
-
-
Chisari, F.V.1
Ferrari, C.2
-
4
-
-
0032841846
-
Pathogenesis of chronic hepatitis C: Immunological features of hepatitis injury and viral persistence
-
Cerny A., Chisari F.V. Pathogenesis of chronic hepatitis C: immunological features of hepatitis injury and viral persistence. Hepatology. 30:1999;595-601.
-
(1999)
Hepatology
, vol.30
, pp. 595-601
-
-
Cerny, A.1
Chisari, F.V.2
-
5
-
-
0029743737
-
Phenotypic analysis of antigen-specific T lymphocytes
-
Altman J.D., Moss P.A.H., Goulder P.J.R., Barouch D.H., McHeyzer-Williams M.G., Bell J.I., McMichael A.J., Davis M.M. Phenotypic analysis of antigen-specific T lymphocytes. Science. 274:1996;94-96.
-
(1996)
Science
, vol.274
, pp. 94-96
-
-
Altman, J.D.1
Moss, P.A.H.2
Goulder, P.J.R.3
Barouch, D.H.4
McHeyzer-Williams, M.G.5
Bell, J.I.6
McMichael, A.J.7
Davis, M.M.8
-
6
-
-
0030219913
-
To kill or to cure: Options in host defense against viral infection
-
Guidotti L.G., Chisari F.V. To kill or to cure: options in host defense against viral infection. Curr Opin Immunol. 8:1996;478-483.
-
(1996)
Curr Opin Immunol
, vol.8
, pp. 478-483
-
-
Guidotti, L.G.1
Chisari, F.V.2
-
7
-
-
0030021968
-
Intracellular inactivation of the hepatitis B virus by cytotoxic T lymphocytes
-
Guidotti L.G., Ishikawa T., Hobbs M.V., Matzke B., Schreiber R., Chisari F.V. Intracellular inactivation of the hepatitis B virus by cytotoxic T lymphocytes. Immunity. 4:1996;25-36.
-
(1996)
Immunity
, vol.4
, pp. 25-36
-
-
Guidotti, L.G.1
Ishikawa, T.2
Hobbs, M.V.3
Matzke, B.4
Schreiber, R.5
Chisari, F.V.6
-
8
-
-
0031060376
-
Distinct organ-dependent mechanisms for the control of murine cytomegalovirus infection by natural killer cells
-
Tay C., Welsh R. Distinct organ-dependent mechanisms for the control of murine cytomegalovirus infection by natural killer cells. J Virol. 71:1997;267-275.
-
(1997)
J Virol
, vol.71
, pp. 267-275
-
-
Tay, C.1
Welsh, R.2
-
9
-
-
0028608085
-
CD8+ T-cell mediated protection against an intracellular bacterium by perforin-dependent cytotoxicity
-
Kagi D., Ledermann B., Burki H., Hengartner H., Zinkernagel R. CD8+ T-cell mediated protection against an intracellular bacterium by perforin-dependent cytotoxicity. Eur J Immunol. 24:1994;3068-3072.
-
(1994)
Eur J Immunol
, vol.24
, pp. 3068-3072
-
-
Kagi, D.1
Ledermann, B.2
Burki, H.3
Hengartner, H.4
Zinkernagel, R.5
-
10
-
-
0033577852
-
Noncytopathic clearance of lymphocytic choriomeningitis virus from the hepatocyte
-
Here the authors demonstrate that LCMV replicating within hepatocytes is susceptible to noncytopathic antiviral control. This work suggests that noncytopathic mechanisms may be more active in parenchymal cells in order to preserve the functional integrity of vital organs such as the liver.
-
Guidotti L.G., Borrow P., Brown A., McClary H., Koch R., Chisari F.V. Noncytopathic clearance of lymphocytic choriomeningitis virus from the hepatocyte. J Exp Med. 189:1999;1555-1564. Here the authors demonstrate that LCMV replicating within hepatocytes is susceptible to noncytopathic antiviral control. This work suggests that noncytopathic mechanisms may be more active in parenchymal cells in order to preserve the functional integrity of vital organs such as the liver.
-
(1999)
J Exp Med
, vol.189
, pp. 1555-1564
-
-
Guidotti, L.G.1
Borrow, P.2
Brown, A.3
McClary, H.4
Koch, R.5
Chisari, F.V.6
-
11
-
-
0033617583
-
Viral clearance without destruction of infected cells during acute HBV infection
-
Shows control of HBV replication in acutely infected chimpanzees before the peak of liver damage and T cell infiltration, highlighting the relevance of noncytopathic mechanisms of viral clearance during acute viral hepatitis in a primate model.
-
Guidotti L.G., Rochford R., Chung J., Shapiro M., Purcell R., Chisari F.V. Viral clearance without destruction of infected cells during acute HBV infection. Science. 284:1999;825-829. Shows control of HBV replication in acutely infected chimpanzees before the peak of liver damage and T cell infiltration, highlighting the relevance of noncytopathic mechanisms of viral clearance during acute viral hepatitis in a primate model.
-
(1999)
Science
, vol.284
, pp. 825-829
-
-
Guidotti, L.G.1
Rochford, R.2
Chung, J.3
Shapiro, M.4
Purcell, R.5
Chisari, F.V.6
-
12
-
-
0031002790
-
Essential roles of the Fas ligand in the development of hepatitis
-
Kondo T., Suda T., Fukuyama H., Adachi M., Nagata S. Essential roles of the Fas ligand in the development of hepatitis. Nat Med. 3:1997;409-413.
-
(1997)
Nat Med
, vol.3
, pp. 409-413
-
-
Kondo, T.1
Suda, T.2
Fukuyama, H.3
Adachi, M.4
Nagata, S.5
-
13
-
-
0033965482
-
Apoptosis and regeneration of hepatocytes during recovery from transient hepadnavirus infections
-
Demonstrates an increased rate of hepatocyte apoptosis and regeneration during control of woodchuck hepatitis virus. This work suggests that a degree of direct hepatocyte lysis is occurring during viral control and that infected cells are replaced by regenerated hepatocytes resistant to further infection.
-
Guo J., Zhou H., Liu C., Aldrich C., Saputelli J., Whitaker T., Inmaculada Barrasa M., Mason W., Seeger C. Apoptosis and regeneration of hepatocytes during recovery from transient hepadnavirus infections. J Virol. 74:2000;1495-1505. Demonstrates an increased rate of hepatocyte apoptosis and regeneration during control of woodchuck hepatitis virus. This work suggests that a degree of direct hepatocyte lysis is occurring during viral control and that infected cells are replaced by regenerated hepatocytes resistant to further infection.
-
(2000)
J Virol
, vol.74
, pp. 1495-1505
-
-
Guo, J.1
Zhou, H.2
Liu, C.3
Aldrich, C.4
Saputelli, J.5
Whitaker, T.6
Inmaculada Barrasa, M.7
Mason, W.8
Seeger, C.9
-
14
-
-
0033119925
-
Analysis of a successful immune response against hepatitis C virus
-
The HCV-specific CTL response is monitored, from the liver of chimpanzees acutely infected with HCV. A multispecific CTL response acting in the early phase of infection correlates with HCV resolution. These CTLs persist in a biochemically and histologically normal liver more than a year after resolution of infection.
-
Cooper S., Erickson A.L., Adams E.J., Kansopon J., Weiner A.J., Chien D.Y., Houghton M., Parham P., Walker C. Analysis of a successful immune response against hepatitis C virus. Immunity. 10:1999;439-449. The HCV-specific CTL response is monitored, from the liver of chimpanzees acutely infected with HCV. A multispecific CTL response acting in the early phase of infection correlates with HCV resolution. These CTLs persist in a biochemically and histologically normal liver more than a year after resolution of infection.
-
(1999)
Immunity
, vol.10
, pp. 439-449
-
-
Cooper, S.1
Erickson, A.L.2
Adams, E.J.3
Kansopon, J.4
Weiner, A.J.5
Chien, D.Y.6
Houghton, M.7
Parham, P.8
Walker, C.9
-
15
-
-
0031068032
-
The role of hepatitis C virus-specific cytotoxic T lymphocytes in chronic hepatitis C
-
Nelson D.R., Marousis C.G., Davis G.L., Rice C.M., Wong J., Houghton M., Lau J.Y. The role of hepatitis C virus-specific cytotoxic T lymphocytes in chronic hepatitis C. J Immunol. 158:1997;1473-1481.
-
(1997)
J Immunol
, vol.158
, pp. 1473-1481
-
-
Nelson, D.R.1
Marousis, C.G.2
Davis, G.L.3
Rice, C.M.4
Wong, J.5
Houghton, M.6
Lau, J.Y.7
-
16
-
-
0032754504
-
Direct ex vivo analysis of hepatitis B virus-specific CD8+ T cells associated with the control of infection
-
Maini M.K., Boni C., Ogg G.S., King A.S., Reignat S., Lee C.K., Larrubia J.R., Webster G.J., McMichael A.J., Ferrari C.et al. Direct ex vivo analysis of hepatitis B virus-specific CD8+ T cells associated with the control of infection. Gastroenterology. 117:1999;1386-1396.
-
(1999)
Gastroenterology
, vol.117
, pp. 1386-1396
-
-
Maini, M.K.1
Boni, C.2
Ogg, G.S.3
King, A.S.4
Reignat, S.5
Lee, C.K.6
Larrubia, J.R.7
Webster, G.J.8
McMichael, A.J.9
Ferrari, C.10
-
17
-
-
13044313467
-
Quantitative analysis of hepatitis C virus-specific CD8+ T cells in peripheral blood and liver using peptide-MHC tetramers
-
+ T cells in peripheral blood and liver using peptide-MHC tetramers.
-
+ T cells in peripheral blood and liver using peptide-MHC tetramers.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 5692-5697
-
-
He, X.-S.1
Rehermann, B.2
Lopez-Labrador, F.X.3
Boisvert, J.4
Cheung, R.5
Mumm, J.6
Wedemeyer, H.7
Berenguer, M.8
Wright, T.L.9
Davis, M.M.10
Greenberg, H.B.11
-
18
-
-
0034678435
-
The role of virus-specific CD8+ cells in viral control and liver damage during persistent hepatitis B virus (HBV) infection
-
The frequency and functional efficiency of HBV-specific CTLs directly from the liver and circulation of chronic HBV patients are correlated with the degree of liver damage and virus control.
-
Maini M.K., Boni C., Lee C.K., Larrubia J.R., Reignat S., Ogg G.S., King A.S., Herberg J., Gilson R., Alisa A.et al. The role of virus-specific CD8+ cells in viral control and liver damage during persistent hepatitis B virus (HBV) infection. J Exp Med. 191:2000;1269-1280. The frequency and functional efficiency of HBV-specific CTLs directly from the liver and circulation of chronic HBV patients are correlated with the degree of liver damage and virus control.
-
(2000)
J Exp Med
, vol.191
, pp. 1269-1280
-
-
Maini, M.K.1
Boni, C.2
Lee, C.K.3
Larrubia, J.R.4
Reignat, S.5
Ogg, G.S.6
King, A.S.7
Herberg, J.8
Gilson, R.9
Alisa, A.10
-
19
-
-
0033230777
-
Human transporter associated with antigen processing (TAPs) select epitope precursor peptides for processing in the endoplasmic reticulum and presentation to T cells
-
Lauvau G., Kakimi K., Niedermann G., Ostankovitch M., Yotnda P., Firat H., Chisari F., van Endert P. Human transporter associated with antigen processing (TAPs) select epitope precursor peptides for processing in the endoplasmic reticulum and presentation to T cells. J Exp Med. 190:1999;1227-1239.
-
(1999)
J Exp Med
, vol.190
, pp. 1227-1239
-
-
Lauvau, G.1
Kakimi, K.2
Niedermann, G.3
Ostankovitch, M.4
Yotnda, P.5
Firat, H.6
Chisari, F.7
Van Endert, P.8
-
20
-
-
0031024723
-
Different cytokine profiles of intraphepatic T cells in chronic hepatitis B and hepatitis C virus infections
-
Bertoletti A., D'Elios M.M., Boni C., De Carli M., Zignego A.L., Durazzo M., Missale G., Penna A., Fiaccadori F., Del Prete G., Ferrari C. Different cytokine profiles of intraphepatic T cells in chronic hepatitis B and hepatitis C virus infections. Gastroenterology. 112:1997;193-199.
-
(1997)
Gastroenterology
, vol.112
, pp. 193-199
-
-
Bertoletti, A.1
D'Elios, M.M.2
Boni, C.3
De Carli, M.4
Zignego, A.L.5
Durazzo, M.6
Missale, G.7
Penna, A.8
Fiaccadori, F.9
Del Prete, G.10
Ferrari, C.11
-
21
-
-
0027319205
-
Compartmentalization of T lymphocytes to the site of disease: Intrahepatic CD4+ T cells specific for the protein NS4 of hepatitis C virus in patients with chronic hepatitis C
-
Minutello M.A., Pileri P., Unutmaz D., Censini S., Kuo G., Houghton M., Brunetto M.R., Bonino F., Abrignani S. Compartmentalization of T lymphocytes to the site of disease: intrahepatic CD4+ T cells specific for the protein NS4 of hepatitis C virus in patients with chronic hepatitis C. J Exp Med. 178:1993;17-25.
-
(1993)
J Exp Med
, vol.178
, pp. 17-25
-
-
Minutello, M.A.1
Pileri, P.2
Unutmaz, D.3
Censini, S.4
Kuo, G.5
Houghton, M.6
Brunetto, M.R.7
Bonino, F.8
Abrignani, S.9
-
22
-
-
0027453541
-
Mechanisms of class I restricted immunopathology. A transgenic mouse model of fulminant hepatitis
-
Ando K., Moriyama T., Guidotti L.G., Wirth S., Schreiber R., Schlicht H., Huang S., Chisari F.V. Mechanisms of class I restricted immunopathology. A transgenic mouse model of fulminant hepatitis. J Exp Med. 178:1993;1541-1554.
-
(1993)
J Exp Med
, vol.178
, pp. 1541-1554
-
-
Ando, K.1
Moriyama, T.2
Guidotti, L.G.3
Wirth, S.4
Schreiber, R.5
Schlicht, H.6
Huang, S.7
Chisari, F.V.8
-
23
-
-
0026643743
-
A T-cell dependent experimental liver injury in mice inducible by concanavalin A
-
Tiegs G., Hentschel J., Wendel A. A T-cell dependent experimental liver injury in mice inducible by concanavalin A. J Clin Invest. 90:1992;196-203.
-
(1992)
J Clin Invest
, vol.90
, pp. 196-203
-
-
Tiegs, G.1
Hentschel, J.2
Wendel, A.3
-
24
-
-
0030017301
-
Interferon gamma plays a critical role in T cell-dependent liver injury in mice initiated by concanavalin A
-
Kusters S., Gantner F., Kunstle G., Tiegs G. Interferon gamma plays a critical role in T cell-dependent liver injury in mice initiated by concanavalin A. Gastroenterology. 111:1996;462-471.
-
(1996)
Gastroenterology
, vol.111
, pp. 462-471
-
-
Kusters, S.1
Gantner, F.2
Kunstle, G.3
Tiegs, G.4
-
25
-
-
0031824006
-
Contribution of virus-specific CD8+ cytotoxic T cells to virus clearance or pathologic manifestations of influenza virus infection in a T cell receptor transgenic mouse model
-
Moskophidis D., Kioussis D. Contribution of virus-specific CD8+ cytotoxic T cells to virus clearance or pathologic manifestations of influenza virus infection in a T cell receptor transgenic mouse model. J Exp Med. 188:1998;223-232.
-
(1998)
J Exp Med
, vol.188
, pp. 223-232
-
-
Moskophidis, D.1
Kioussis, D.2
-
26
-
-
0028848472
-
Role of interferon-gamma in immune cell regulation
-
Young H.A., Hardy K.J. Role of interferon-gamma in immune cell regulation. J Leukoc Biol. 58:1995;373-381.
-
(1995)
J Leukoc Biol
, vol.58
, pp. 373-381
-
-
Young, H.A.1
Hardy, K.J.2
-
27
-
-
0029025483
-
Protective effect of hepatocyte growth factor on interferon-gamma-induced cytotoxicity in mouse hepatocytes
-
Morita M., Watanabe Y., Akaike T. Protective effect of hepatocyte growth factor on interferon-gamma-induced cytotoxicity in mouse hepatocytes. Hepatology. 21:1995;1585-1593.
-
(1995)
Hepatology
, vol.21
, pp. 1585-1593
-
-
Morita, M.1
Watanabe, Y.2
Akaike, T.3
-
28
-
-
0027157494
-
Preferential migration of activated CD4+ and CD8+ T cells in response to MIP-1α and MIP-1β
-
Taub D.D., Conlon K., Lloyd A.R., Oppenheim J.J., Kelvin D.J. Preferential migration of activated CD4+ and CD8+ T cells in response to MIP-1α and MIP-1β Science. 260:1993;355-357.
-
(1993)
Science
, vol.260
, pp. 355-357
-
-
Taub, D.D.1
Conlon, K.2
Lloyd, A.R.3
Oppenheim, J.J.4
Kelvin, D.J.5
-
29
-
-
0028979682
-
Requirement of MIP-1α for an inflammatory response to viral infection
-
Cook D., Beck M., Coffman T., Kirby S., Sheridan J., Pragnell I., Smithies O. Requirement of MIP-1α for an inflammatory response to viral infection. Science. 269:1995;1583-1586.
-
(1995)
Science
, vol.269
, pp. 1583-1586
-
-
Cook, D.1
Beck, M.2
Coffman, T.3
Kirby, S.4
Sheridan, J.5
Pragnell, I.6
Smithies, O.7
-
30
-
-
0033485942
-
Chemokine and chemokine receptor interactions provide a mechanism for selective T cell recruitment to specific liver compartments within hepatitis C infected liver
-
Links the expression of different chemokines and chemokine receptors to preferential T cell recruitment to specific anatomical sites within an HCV-infected liver.
-
Shields P.L., Morland C.M., Salmon M., Qin S., Hubscher S.G., Adams D.H. Chemokine and chemokine receptor interactions provide a mechanism for selective T cell recruitment to specific liver compartments within hepatitis C infected liver. J Immunol. 163:1999;6236-6243. Links the expression of different chemokines and chemokine receptors to preferential T cell recruitment to specific anatomical sites within an HCV-infected liver.
-
(1999)
J Immunol
, vol.163
, pp. 6236-6243
-
-
Shields, P.L.1
Morland, C.M.2
Salmon, M.3
Qin, S.4
Hubscher, S.G.5
Adams, D.H.6
-
31
-
-
0031974018
-
Early murine cytomegalovirus (MCMV) infection induces liver natural killer (NK) cell inflammation and protection through macrophage inflammatory protein 1α (MIP-1α)-dependent pathways
-
Salazar-Mather T.P., Orange J.S., Biron C.A. Early murine cytomegalovirus (MCMV) infection induces liver natural killer (NK) cell inflammation and protection through macrophage inflammatory protein 1α (MIP-1α)-dependent pathways. J Exp Med. 187:1998;1-14.
-
(1998)
J Exp Med
, vol.187
, pp. 1-14
-
-
Salazar-Mather, T.P.1
Orange, J.S.2
Biron, C.A.3
-
32
-
-
0034598156
-
Augmentation of Vα14 NKT cell-mediated cytotoxicity by interleukin-4 in an autocrine mechanism resulting in the development of Concanavalin A-induced hepatitis
-
Demonstrates the importance of NKT cells and of perforin/Fas-ligand molecules in the development of liver inflammation.
-
Kaneko Y.B., Harada M., Kawano T., Yamashita M., Shibata Y., Gejco F., Nakayama T., Taniguchi M. Augmentation of Vα14 NKT cell-mediated cytotoxicity by interleukin-4 in an autocrine mechanism resulting in the development of Concanavalin A-induced hepatitis. J Exp Med. 191:2000;105-114. Demonstrates the importance of NKT cells and of perforin/Fas-ligand molecules in the development of liver inflammation.
-
(2000)
J Exp Med
, vol.191
, pp. 105-114
-
-
Kaneko, Y.B.1
Harada, M.2
Kawano, T.3
Yamashita, M.4
Shibata, Y.5
Gejco, F.6
Nakayama, T.7
Taniguchi, M.8
-
33
-
-
0028012009
-
Chronic active hepatitis in transgenic mice expressing interferon-gamma in the liver
-
Toyonaga T., Hino O., Sugai S., Wakasugi S., Abe K., Shichiri M., Yamamura K. Chronic active hepatitis in transgenic mice expressing interferon-gamma in the liver. Proc Natl Acad Sci USA. 91:1994;614-618.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 614-618
-
-
Toyonaga, T.1
Hino, O.2
Sugai, S.3
Wakasugi, S.4
Abe, K.5
Shichiri, M.6
Yamamura, K.7
-
34
-
-
0029810790
-
Progressive liver injury in chronic hepatitis C infection correlates with increased intrahepatic expression of Th1-associated cytokines
-
Napoli J., Bishop G.A., McGuinness P.H., Painter D.M., McCaughan G.W. Progressive liver injury in chronic hepatitis C infection correlates with increased intrahepatic expression of Th1-associated cytokines. Hepatology. 24:1996;759-765.
-
(1996)
Hepatology
, vol.24
, pp. 759-765
-
-
Napoli, J.1
Bishop, G.A.2
McGuinness, P.H.3
Painter, D.M.4
McCaughan, G.W.5
-
35
-
-
0034015514
-
Immunopathogenesis of hepatitis B virus recurrence after liver transplantation
-
Marinos G., Rossol S., Carucci P., Wong P.Y., Donaldson P., Hussain M.J., Vergani D., Portmann B.C., Williams R., Naoumov N.V. Immunopathogenesis of hepatitis B virus recurrence after liver transplantation. Transplantation. 69:2000;559-568.
-
(2000)
Transplantation
, vol.69
, pp. 559-568
-
-
Marinos, G.1
Rossol, S.2
Carucci, P.3
Wong, P.Y.4
Donaldson, P.5
Hussain, M.J.6
Vergani, D.7
Portmann, B.C.8
Williams, R.9
Naoumov, N.V.10
-
36
-
-
0033579819
-
CD40 activation induces apoptosis in cultured human hepatocytes via induction of cell surface Fas ligand expression and amplifies Fas-mediated hepatocyte death during allograft rejection
-
Engagement of the CD40 molecule in hepatocytes amplifies Fas-dependent hepatocyte death - a proposed mechanism of liver damage that may be active in a broad range of inflammatory liver diseases.
-
Afford S.C., Randhawa S., Eliopoulos A.G., Hubscher S.G., Young L.S., Adams D.H. CD40 activation induces apoptosis in cultured human hepatocytes via induction of cell surface Fas ligand expression and amplifies Fas-mediated hepatocyte death during allograft rejection. J Exp Med. 189:1999;441-446. Engagement of the CD40 molecule in hepatocytes amplifies Fas-dependent hepatocyte death - a proposed mechanism of liver damage that may be active in a broad range of inflammatory liver diseases.
-
(1999)
J Exp Med
, vol.189
, pp. 441-446
-
-
Afford, S.C.1
Randhawa, S.2
Eliopoulos, A.G.3
Hubscher, S.G.4
Young, L.S.5
Adams, D.H.6
-
37
-
-
0028178484
-
"occult" hepatitis B virus as a source of infection in liver transplant recipients
-
Chazouilleres O., Mamish D., Kim M., Carey K., Ferrel L., Roberts J., Acsher N.L., Wright T.L. "Occult" hepatitis B virus as a source of infection in liver transplant recipients. Lancet. 343:1994;142-146.
-
(1994)
Lancet
, vol.343
, pp. 142-146
-
-
Chazouilleres, O.1
Mamish, D.2
Kim, M.3
Carey, K.4
Ferrel, L.5
Roberts, J.6
Acsher, N.L.7
Wright, T.L.8
-
38
-
-
0033168022
-
Occult hepatitis B virus infection in patients with chronic hepatitis C liver disease
-
Cacciola I., Pollicino T., Squadrito G., Cerenzia G., Orlando M.E., Raimondo G. Occult hepatitis B virus infection in patients with chronic hepatitis C liver disease. N Engl J Med. 341:1999;22-26.
-
(1999)
N Engl J Med
, vol.341
, pp. 22-26
-
-
Cacciola, I.1
Pollicino, T.2
Squadrito, G.3
Cerenzia, G.4
Orlando, M.E.5
Raimondo, G.6
-
40
-
-
9544232506
-
Long-lasting memory T cell responses following self-limited acute hepatitis B
-
Penna A., Artini M., Cavalli A., Levrero M., Bertoletti A., Pilli M., Chisari F.V., Rehermann B., Del Prete G., Fiaccadori F., Ferrari C. Long-lasting memory T cell responses following self-limited acute hepatitis B. J Clin Invest. 98:1996;1185-1194.
-
(1996)
J Clin Invest
, vol.98
, pp. 1185-1194
-
-
Penna, A.1
Artini, M.2
Cavalli, A.3
Levrero, M.4
Bertoletti, A.5
Pilli, M.6
Chisari, F.V.7
Rehermann, B.8
Del Prete, G.9
Fiaccadori, F.10
Ferrari, C.11
-
41
-
-
0029838758
-
The hepatitis B virus persists for decades after patients' recovery from acute viral hepatitis despite active maintenance of a cytotoxic T-lymphocyte response
-
Rehermann B., Ferrari C., Pasquinelli C., Chisari F.V. The hepatitis B virus persists for decades after patients' recovery from acute viral hepatitis despite active maintenance of a cytotoxic T-lymphocyte response. Nat Med. 2:1996;1104-1108.
-
(1996)
Nat Med
, vol.2
, pp. 1104-1108
-
-
Rehermann, B.1
Ferrari, C.2
Pasquinelli, C.3
Chisari, F.V.4
-
42
-
-
0033952115
-
Latent hepatitis B virus infection in healthy individuals with antibodies to hepatitis B core antigen
-
Marusawa H., Uemoto S., Hijikata M., Ueda Y., Tanaka K., Shimothono K., Chiba T. Latent hepatitis B virus infection in healthy individuals with antibodies to hepatitis B core antigen. Hepatology. 31:2000;488-495.
-
(2000)
Hepatology
, vol.31
, pp. 488-495
-
-
Marusawa, H.1
Uemoto, S.2
Hijikata, M.3
Ueda, Y.4
Tanaka, K.5
Shimothono, K.6
Chiba, T.7
-
43
-
-
17544369397
-
Quantification of intrahepatic hepatitis B virus (HBV) DNA in patients with chronic HBV infection
-
Cacciola I., Pollicino T., Squadrito G., Cerenzia G., Villari D., De Franchis R., Sanantonio T., Brancatelli S., Colucci G., Raimondo G. Quantification of intrahepatic hepatitis B virus (HBV) DNA in patients with chronic HBV infection. Hepatology. 31:2000;507-512.
-
(2000)
Hepatology
, vol.31
, pp. 507-512
-
-
Cacciola, I.1
Pollicino, T.2
Squadrito, G.3
Cerenzia, G.4
Villari, D.5
De Franchis, R.6
Sanantonio, T.7
Brancatelli, S.8
Colucci, G.9
Raimondo, G.10
-
44
-
-
0031778788
-
Molecular basis for persistent hepatitis B virus infection in the liver after clearance of serum hepatitis B surface antigen
-
Mason A.L., Xu L., Guo L., Kuhns M., Perrillo R.P. Molecular basis for persistent hepatitis B virus infection in the liver after clearance of serum hepatitis B surface antigen. Hepatology. 27:1998;1736-1742.
-
(1998)
Hepatology
, vol.27
, pp. 1736-1742
-
-
Mason, A.L.1
Xu, L.2
Guo, L.3
Kuhns, M.4
Perrillo, R.P.5
-
45
-
-
0028179993
-
Circulating anti-Tax cytotoxic T lymphocytes from human T-cell leukaemia virus type I-infected people, with and without tropical spastic paraparesis, recognize multiple epitopes simultaneously
-
Parker C.E., Nightingale S., Taylor G.P., Weber J., Bangham C.R. Circulating anti-Tax cytotoxic T lymphocytes from human T-cell leukaemia virus type I-infected people, with and without tropical spastic paraparesis, recognize multiple epitopes simultaneously. J Virol. 68:1994;2860-2868.
-
(1994)
J Virol
, vol.68
, pp. 2860-2868
-
-
Parker, C.E.1
Nightingale, S.2
Taylor, G.P.3
Weber, J.4
Bangham, C.R.5
-
46
-
-
0033082487
-
A re-evaluation of the frequency of CD8+ T cells specific for EBV in healthy virus carriers
-
Tan L.C., Gudgeon N., Annels N.E., Hansasuta P., O'Callaghan C.A., Rowland-Jones S., McMichael A.J., Rickinson A.B., Callan M.F. A re-evaluation of the frequency of CD8+ T cells specific for EBV in healthy virus carriers. J Immunol. 162:1999;1827-1835.
-
(1999)
J Immunol
, vol.162
, pp. 1827-1835
-
-
Tan, L.C.1
Gudgeon, N.2
Annels, N.E.3
Hansasuta, P.4
O'Callaghan, C.A.5
Rowland-Jones, S.6
McMichael, A.J.7
Rickinson, A.B.8
Callan, M.F.9
-
47
-
-
0034192426
-
CD8+ T cells can block herpes simplex virus type 1 (HSV-1) reactivation from latency in sensory neurons
-
Liu T., Khanna K.M., Chen X.P., Fink D.J., Hendricks R.L. CD8+ T cells can block herpes simplex virus type 1 (HSV-1) reactivation from latency in sensory neurons. J Exp Med. 191:2000;1459-1466.
-
(2000)
J Exp Med
, vol.191
, pp. 1459-1466
-
-
Liu, T.1
Khanna, K.M.2
Chen, X.P.3
Fink, D.J.4
Hendricks, R.L.5
-
48
-
-
0029985351
-
Population dynamics of immune responses to persistent viruses
-
Nowak M.A., Bangham C.R. Population dynamics of immune responses to persistent viruses. Science. 272:1996;74-79.
-
(1996)
Science
, vol.272
, pp. 74-79
-
-
Nowak, M.A.1
Bangham, C.R.2
-
49
-
-
0028360076
-
Natural variants of cytotoxic epitopes are T-cell receptor antagonists for antiviral cytotoxic T cells
-
Bertoletti A., Sette A., Chisari F.V., Penna A., Levrero M., De Carli M., Fiaccadori F., Ferrari C. Natural variants of cytotoxic epitopes are T-cell receptor antagonists for antiviral cytotoxic T cells. Nature. 369:1994;407-410.
-
(1994)
Nature
, vol.369
, pp. 407-410
-
-
Bertoletti, A.1
Sette, A.2
Chisari, F.V.3
Penna, A.4
Levrero, M.5
De Carli, M.6
Fiaccadori, F.7
Ferrari, C.8
-
50
-
-
0031680261
-
Hepatitis C virus variants circumventing cytotoxic T lymphocyte activity as a mechanism of chronicity
-
Tsai S.L., Chen Y.M., Chen M.H., Huang C.Y., Sheen I.S., Yeh C.T., Huang J.H., Kuo G.C., Liaw Y.F. Hepatitis C virus variants circumventing cytotoxic T lymphocyte activity as a mechanism of chronicity. Gastroenterology. 115:1998;954-966.
-
(1998)
Gastroenterology
, vol.115
, pp. 954-966
-
-
Tsai, S.L.1
Chen, Y.M.2
Chen, M.H.3
Huang, C.Y.4
Sheen, I.S.5
Yeh, C.T.6
Huang, J.H.7
Kuo, G.C.8
Liaw, Y.F.9
-
51
-
-
0033962529
-
Effects of age and viral determinants on chronicity as an outcome of experimental woodchuck hepatitis virus infection
-
Cote P.J., Korba B.E., Miller R.H., Jacob J.R., Baldwin B.H., Hornbuckle W.E., Purcell R.H., Tennant B.C., Gerin J.L. Effects of age and viral determinants on chronicity as an outcome of experimental woodchuck hepatitis virus infection. Hepatology. 31:2000;190-200.
-
(2000)
Hepatology
, vol.31
, pp. 190-200
-
-
Cote, P.J.1
Korba, B.E.2
Miller, R.H.3
Jacob, J.R.4
Baldwin, B.H.5
Hornbuckle, W.E.6
Purcell, R.H.7
Tennant, B.C.8
Gerin, J.L.9
-
52
-
-
0031446517
-
A functional and kinetic comparison of antiviral effector and memory cytotoxic T lymphocyte populations in vivo and in vitro
-
Ehl S., Klenerman P., Aichele P., Hengartner H., Zinkernagel R.M. A functional and kinetic comparison of antiviral effector and memory cytotoxic T lymphocyte populations in vivo and in vitro. Eur J Immunol. 27:1997;3404-3413.
-
(1997)
Eur J Immunol
, vol.27
, pp. 3404-3413
-
-
Ehl, S.1
Klenerman, P.2
Aichele, P.3
Hengartner, H.4
Zinkernagel, R.M.5
-
53
-
-
0033579928
-
Migration kinetics and final destination of type 1 and type 2 CD8 effector cells predict protection against pulmonary virus infection
-
The migration potential of CTLs is shown to influence the outcome of virus infection.
-
Cerwenka A., Morgan T.M., Harmsen A.G., Dutton R.W. Migration kinetics and final destination of type 1 and type 2 CD8 effector cells predict protection against pulmonary virus infection. J Exp Med. 189:1999;423-434. The migration potential of CTLs is shown to influence the outcome of virus infection.
-
(1999)
J Exp Med
, vol.189
, pp. 423-434
-
-
Cerwenka, A.1
Morgan, T.M.2
Harmsen, A.G.3
Dutton, R.W.4
-
54
-
-
0028925535
-
The cytotoxic T lymphocyte response to multiple hepatitis B virus polymerase epitopes during and after acute viral hepatitis
-
Rehermann B., Fowler P., Sidney J., Person J., Redeker A., Brown M., Moss B., Sette A., Chisari F.V. The cytotoxic T lymphocyte response to multiple hepatitis B virus polymerase epitopes during and after acute viral hepatitis. J Exp Med. 181:1995;1047-1058.
-
(1995)
J Exp Med
, vol.181
, pp. 1047-1058
-
-
Rehermann, B.1
Fowler, P.2
Sidney, J.3
Person, J.4
Redeker, A.5
Brown, M.6
Moss, B.7
Sette, A.8
Chisari, F.V.9
-
55
-
-
0025245580
-
Cellular immune response to hepatitis B virus encoded antigens in acute and chronic hepatitis B virus infection
-
Ferrari C., Penna A., Bertoletti A., Valli A., Degli Antoni A., Giuberti T., Cavalli A., Petit M.A., Fiaccadori F. Cellular immune response to hepatitis B virus encoded antigens in acute and chronic hepatitis B virus infection. J Immunol. 145:1990;3442-3449.
-
(1990)
J Immunol
, vol.145
, pp. 3442-3449
-
-
Ferrari, C.1
Penna, A.2
Bertoletti, A.3
Valli, A.4
Degli Antoni, A.5
Giuberti, T.6
Cavalli, A.7
Petit, M.A.8
Fiaccadori, F.9
-
56
-
-
0026040543
-
Hepatitis B virus antigen-specific T-cell activation in patients with acute and chronic hepatitis B
-
Jung M., Spengler U., Schraut W., Hoffman R., Zachoval R., Eisemburg J., Eichenlaub D., Riethmuller G., Paumgartner G., Ziegler-Heitbrock H.W.L., Pape G.R. Hepatitis B virus antigen-specific T-cell activation in patients with acute and chronic hepatitis B. J Hepatol. 13:1991;310-317.
-
(1991)
J Hepatol
, vol.13
, pp. 310-317
-
-
Jung, M.1
Spengler, U.2
Schraut, W.3
Hoffman, R.4
Zachoval, R.5
Eisemburg, J.6
Eichenlaub, D.7
Riethmuller, G.8
Paumgartner, G.9
Ziegler-Heitbrock, H.W.L.10
Pape, G.R.11
-
57
-
-
10244225383
-
Different clinical behaviors of acute hepatitis C virus infection are associated with different vigor of the anti-viral cell-mediated immune response
-
Missale G., Bertoni R., Lamonaca V., Valli A., Massari M., Mori C., Rumi M., Houghton M., Fiaccadori F., Ferrari C. Different clinical behaviors of acute hepatitis C virus infection are associated with different vigor of the anti-viral cell-mediated immune response. J Clin Invest. 98:1996;706-714.
-
(1996)
J Clin Invest
, vol.98
, pp. 706-714
-
-
Missale, G.1
Bertoni, R.2
Lamonaca, V.3
Valli, A.4
Massari, M.5
Mori, C.6
Rumi, M.7
Houghton, M.8
Fiaccadori, F.9
Ferrari, C.10
-
58
-
-
0029151623
-
Possible mechanism involving T-lymphocyte response to non-structural protein 3 in viral clearance in acute hepatitis C virus infection
-
Diepolder H.M., Zachoval R., Hoffmann R.M., Wierenga E., Santantonio T., Jung M.C., Eichenlaub D., Pape G.R. Possible mechanism involving T-lymphocyte response to non-structural protein 3 in viral clearance in acute hepatitis C virus infection. Lancet. 346:1995;1006-1007.
-
(1995)
Lancet
, vol.346
, pp. 1006-1007
-
-
Diepolder, H.M.1
Zachoval, R.2
Hoffmann, R.M.3
Wierenga, E.4
Santantonio, T.5
Jung, M.C.6
Eichenlaub, D.7
Pape, G.R.8
-
59
-
-
0032832514
-
Recurrence of hepatitis C virus after loss of virus-specific CD4+ T-cell response in acute hepatitis C
-
Gerlach J., Diepolder H.M., Jung M.C., Gruener N., Schraut W., Zachoval R., Hoffmann R.M., Schirren C., Santantonio T., Pape G. Recurrence of hepatitis C virus after loss of virus-specific CD4+ T-cell response in acute hepatitis C. Gastroenterology. 117:1999;933-941.
-
(1999)
Gastroenterology
, vol.117
, pp. 933-941
-
-
Gerlach, J.1
Diepolder, H.M.2
Jung, M.C.3
Gruener, N.4
Schraut, W.5
Zachoval, R.6
Hoffmann, R.M.7
Schirren, C.8
Santantonio, T.9
Pape, G.10
-
60
-
-
0032985725
-
Hepatitis C virus (HCV) specific immune responses in anti-HCV positive patients with hepatitis C viraemia
-
Cramp M.E., Carucci P., Rossol S., Chokshi S., Maertens G., Williams R., Naoumov N.V. Hepatitis C virus (HCV) specific immune responses in anti-HCV positive patients with hepatitis C viraemia. Gut. 44:1999;424-429.
-
(1999)
Gut
, vol.44
, pp. 424-429
-
-
Cramp, M.E.1
Carucci, P.2
Rossol, S.3
Chokshi, S.4
Maertens, G.5
Williams, R.6
Naoumov, N.V.7
-
61
-
-
0031740004
-
Dynamics of intra-hepatic lymphocytes in chronic hepatitis C: Enrichment for Vα 24+ T cells and rapid elimination of effector cell by apoptosis
-
Nuti S., Rosa D., Valiante N., Saletti G., Caratazzolo M., Dellabona P., Barnaba V., Abrignani S. Dynamics of intra-hepatic lymphocytes in chronic hepatitis C: enrichment for Vα 24+ T cells and rapid elimination of effector cell by apoptosis. Eur J Immunol. 28:1998;3448-3455.
-
(1998)
Eur J Immunol
, vol.28
, pp. 3448-3455
-
-
Nuti, S.1
Rosa, D.2
Valiante, N.3
Saletti, G.4
Caratazzolo, M.5
Dellabona, P.6
Barnaba, V.7
Abrignani, S.8
-
62
-
-
0031019163
-
Activation and function of natural killer cell responses during viral infections
-
Biron C. Activation and function of natural killer cell responses during viral infections. Curr Opin Immunol. 9:1997;24-34.
-
(1997)
Curr Opin Immunol
, vol.9
, pp. 24-34
-
-
Biron, C.1
-
63
-
-
0029965776
-
One step ahead of the game: Viral immunomodulatory molecules
-
Spriggs M.K. One step ahead of the game: viral immunomodulatory molecules. Annu Rev Immunol. 14:1996;101-130.
-
(1996)
Annu Rev Immunol
, vol.14
, pp. 101-130
-
-
Spriggs, M.K.1
-
64
-
-
0034142387
-
Modulating chemokines: More lessons from viruses
-
Lalani A.S., Barrett J.W., McFadden G. Modulating chemokines: more lessons from viruses. Immunol Today. 21:2000;100-106.
-
(2000)
Immunol Today
, vol.21
, pp. 100-106
-
-
Lalani, A.S.1
Barrett, J.W.2
McFadden, G.3
-
65
-
-
0033556262
-
Suppression of host immune response by the core protein of hepatitis C virus: Possible implications for hepatitis C virus persistence
-
Large M.K., Kittlesen D.J., Hahn Y.S. Suppression of host immune response by the core protein of hepatitis C virus: possible implications for hepatitis C virus persistence. J Immunol. 162:1999;931-938.
-
(1999)
J Immunol
, vol.162
, pp. 931-938
-
-
Large, M.K.1
Kittlesen, D.J.2
Hahn, Y.S.3
-
66
-
-
0032824134
-
Expression of hepatitis C virus proteins inhibits signal transduction through the Jak-STAT pathway
-
Heim M.H., Moradpour D., Blum H.E. Expression of hepatitis C virus proteins inhibits signal transduction through the Jak-STAT pathway. J Virol. 73:1999;8469-8475.
-
(1999)
J Virol
, vol.73
, pp. 8469-8475
-
-
Heim, M.H.1
Moradpour, D.2
Blum, H.E.3
-
67
-
-
0033516497
-
Inhibition of interferon-inducible protein kinase PKR by HCV E2 protein
-
Taylor D.R., Shi S.T., Romano P.R., Barber G., Lai M. Inhibition of interferon-inducible protein kinase PKR by HCV E2 protein. Science. 285:1999;107-110.
-
(1999)
Science
, vol.285
, pp. 107-110
-
-
Taylor, D.R.1
Shi, S.T.2
Romano, P.R.3
Barber, G.4
Lai, M.5
-
68
-
-
0033104746
-
Altered helper T lymphocyte function associated with chronic hepatitis B virus infection and its role in response to therapeutic vaccination in humans
-
Livingston B.D., Alexander J., Crimi C., Oseroff C., Celis E., Daly K., Guidotti L.G., Chisari F.V., Fikes J., Chesnut R.W., Sette A. Altered helper T lymphocyte function associated with chronic hepatitis B virus infection and its role in response to therapeutic vaccination in humans. J Immunol. 162:1999;3088-3095.
-
(1999)
J Immunol
, vol.162
, pp. 3088-3095
-
-
Livingston, B.D.1
Alexander, J.2
Crimi, C.3
Oseroff, C.4
Celis, E.5
Daly, K.6
Guidotti, L.G.7
Chisari, F.V.8
Fikes, J.9
Chesnut, R.W.10
Sette, A.11
-
69
-
-
0032169470
-
Lamivudine treatment can restore T cell responsiveness in chronic hepatitis B
-
Boni C., Bertoletti A., Penna A., Cavalli A., Pilli M., Urbani S., Scognamiglio P., Boheme R., Panebianco R., Fiaccadori F., Ferrari C. Lamivudine treatment can restore T cell responsiveness in chronic hepatitis B. J Clin Invest. 102:1998;968-975.
-
(1998)
J Clin Invest
, vol.102
, pp. 968-975
-
-
Boni, C.1
Bertoletti, A.2
Penna, A.3
Cavalli, A.4
Pilli, M.5
Urbani, S.6
Scognamiglio, P.7
Boheme, R.8
Panebianco, R.9
Fiaccadori, F.10
Ferrari, C.11
-
70
-
-
0031872341
-
Immune pathogenesis of hepatocellular carcinoma
-
Nakamoto Y., Guidotti L.G., Kuhlen C., Fowler P., Chisari F.V. Immune pathogenesis of hepatocellular carcinoma. J Exp Med. 188:1998;341-350.
-
(1998)
J Exp Med
, vol.188
, pp. 341-350
-
-
Nakamoto, Y.1
Guidotti, L.G.2
Kuhlen, C.3
Fowler, P.4
Chisari, F.V.5
|