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Volumn 44, Issue 3, 1999, Pages 424-429

Hepatitis C virus (HCV) specific immune responses in anti-HCV positive patients without hepatitis C viraemia

Author keywords

Hepatitis C virus; Liver; T helper cytokines; Th1 Th2 cells; Viral clearance

Indexed keywords

GAMMA INTERFERON; HEPATITIS C ANTIBODY; VIRUS PROTEIN; VIRUS RNA;

EID: 0032985725     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.44.3.424     Document Type: Article
Times cited : (111)

References (37)
  • 2
    • 0028929431 scopus 로고
    • To C or not to C: These are the questions
    • Alter HJ. To C or not to C: these are the questions. Blood 1995;85:1681-95.
    • (1995) Blood , vol.85 , pp. 1681-1695
    • Alter, H.J.1
  • 3
    • 0027068086 scopus 로고
    • The natural history of community-acquired hepatitis C in the United States. The Sentinel Counties Chronic non-A, non-B Hepatitis Study Team
    • Alter MJ, Margolis HS, Krawczynski K, et al. The natural history of community-acquired hepatitis C in the United States. The Sentinel Counties Chronic non-A, non-B Hepatitis Study Team [see comments]. N Engl J Med 1992;327:1899-905.
    • (1992) N Engl J Med , vol.327 , pp. 1899-1905
    • Alter, M.J.1    Margolis, H.S.2    Krawczynski, K.3
  • 4
    • 15844389654 scopus 로고    scopus 로고
    • Routes of infection, viremia, and liver disease in blood donors found to have hepatitis C virus liver infection
    • Cory-Cantilena C, VanRaden M, Gibble J, et al. Routes of infection, viremia, and liver disease in blood donors found to have hepatitis C virus liver infection. N Engl J Med 1996; 344:1691-6.
    • (1996) N Engl J Med , vol.344 , pp. 1691-1696
    • Cory-Cantilena, C.1    VanRaden, M.2    Gibble, J.3
  • 5
    • 0027519138 scopus 로고
    • T-lymphocyte response to hepatitis C virus in different clinical courses of infection
    • Botarelli P, Brunetto MR, Minutello MA, et al. T-lymphocyte response to hepatitis C virus in different clinical courses of infection. Gastroenterology 1993;104: 580-7.
    • (1993) Gastroenterology , vol.104 , pp. 580-587
    • Botarelli, P.1    Brunetto, M.R.2    Minutello, M.A.3
  • 6
    • 0028906422 scopus 로고
    • Mapping of immunodominant CD4+ T lymphocyte epitopes of hepatitis C virus antigens and their relevance during the course of chronic infection
    • Hoffmann RM, Diepolder HM, Zachoval R, et al. Mapping of immunodominant CD4+ T lymphocyte epitopes of hepatitis C virus antigens and their relevance during the course of chronic infection. Hepatology 1995;21:632-8.
    • (1995) Hepatology , vol.21 , pp. 632-638
    • Hoffmann, R.M.1    Diepolder, H.M.2    Zachoval, R.3
  • 7
    • 0029778817 scopus 로고    scopus 로고
    • Quantitative analysis of the peripheral blood cytotoxic T lymphocyte response in patients with chronic hepatitis C virus infection
    • Rehermann B, Chang KM, McHutchison JG, et al. Quantitative analysis of the peripheral blood cytotoxic T lymphocyte response in patients with chronic hepatitis C virus infection. J Clin Invest 1996;98:1432-40.
    • (1996) J Clin Invest , vol.98 , pp. 1432-1440
    • Rehermann, B.1    Chang, K.M.2    McHutchison, J.G.3
  • 8
    • 0028962927 scopus 로고
    • Patients with chronic hepatitis C have circulating cytotoxic T cells which recognize hepatitis C virus-encoded peptides binding to HLA-A2.1 molecules
    • Battegay M, Fikes J, Di Bisceglie AM, et al. Patients with chronic hepatitis C have circulating cytotoxic T cells which recognize hepatitis C virus-encoded peptides binding to HLA-A2.1 molecules. J Virol 1995;69:2462-70.
    • (1995) J Virol , vol.69 , pp. 2462-2470
    • Battegay, M.1    Fikes, J.2    Di Bisceglie, A.M.3
  • 9
    • 0024377134 scopus 로고
    • Detection of antibody to hepatitis C virus in prospectively followed transfusion recipients with acute and chronic non-A, non-B hepatitis
    • Alter HJ, Purcell RH, Shih JW, et al. Detection of antibody to hepatitis C virus in prospectively followed transfusion recipients with acute and chronic non-A, non-B hepatitis. N Engl J Med 1989;321:1494-500.
    • (1989) N Engl J Med , vol.321 , pp. 1494-1500
    • Alter, H.J.1    Purcell, R.H.2    Shih, J.W.3
  • 10
    • 0028087985 scopus 로고
    • Prevention of hepatitis C virus infection in chimpanzees after antibody-mediated in vitro neutralization
    • Farci P, Alter HJ, Wong DC, et al. Prevention of hepatitis C virus infection in chimpanzees after antibody-mediated in vitro neutralization. Proc Natl Acad Sci USA 1994;91: 7792-6.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 7792-7796
    • Farci, P.1    Alter, H.J.2    Wong, D.C.3
  • 11
    • 0028158455 scopus 로고
    • Hepatitis C virus in multiple episodes of acute hepatitis in polytransfused thalassaemic children
    • Lai ME, Mazzoleni AP, Argiolu F, et al. Hepatitis C virus in multiple episodes of acute hepatitis in polytransfused thalassaemic children. Lancet 1994;343:388-90.
    • (1994) Lancet , vol.343 , pp. 388-390
    • Lai, M.E.1    Mazzoleni, A.P.2    Argiolu, F.3
  • 12
    • 0026767691 scopus 로고
    • Lack of protective immunity against reinfection with hepatitis C virus
    • Farci P, Alter HJ, Govindarajan S, et al. Lack of protective immunity against reinfection with hepatitis C virus. Science 1992;258:135-40.
    • (1992) Science , vol.258 , pp. 135-140
    • Farci, P.1    Alter, H.J.2    Govindarajan, S.3
  • 13
    • 0022640843 scopus 로고
    • Two types of murine helper T cell clone. 1. Definition according to profiles of lymphokine activities and secreted proteins
    • Mosmann TR, Cherwinski H, Bond MW, et al. Two types of murine helper T cell clone. 1. Definition according to profiles of lymphokine activities and secreted proteins. J Immunol 1986;136:2348-57.
    • (1986) J Immunol , vol.136 , pp. 2348-2357
    • Mosmann, T.R.1    Cherwinski, H.2    Bond, M.W.3
  • 14
    • 0028220289 scopus 로고
    • Human Th1 and Th2 cells: Functional properties, mechanisms of regulation, and role in disease
    • Del Prete G, Maggi E, Romagnani S. Human Th1 and Th2 cells: functional properties, mechanisms of regulation, and role in disease. Lab Invest 1994;70:299-306.
    • (1994) Lab Invest , vol.70 , pp. 299-306
    • Del Prete, G.1    Maggi, E.2    Romagnani, S.3
  • 15
    • 43949158538 scopus 로고
    • The Th1-Th2 hypothesis of HIV infection: New insights
    • Clerici M, Shearer GM. The Th1-Th2 hypothesis of HIV infection: new insights. Immunol Today 1994;15:575-81.
    • (1994) Immunol Today , vol.15 , pp. 575-581
    • Clerici, M.1    Shearer, G.M.2
  • 16
    • 0026095666 scopus 로고
    • Defining protective responses to pathogens: Cytokine profiles in leprosy lesions
    • published correction appears in Science 1992; 255:12
    • Yamamura M, Uyemura K, Deans RJ, et al. Defining protective responses to pathogens: cytokine profiles in leprosy lesions [published correction appears in Science 1992; 255:12]. Science 1991;254:277-9.
    • (1991) Science , vol.254 , pp. 277-279
    • Yamamura, M.1    Uyemura, K.2    Deans, R.J.3
  • 17
    • 11944260844 scopus 로고
    • Role of T-cell derived cytokines in the downregulation of immune responses in parasitic and retroviral infection
    • Sher A, Gazzinelli RT, Oswald IP, et al. Role of T-cell derived cytokines in the downregulation of immune responses in parasitic and retroviral infection. Immunol Rev 1992;127:183-204.
    • (1992) Immunol Rev , vol.127 , pp. 183-204
    • Sher, A.1    Gazzinelli, R.T.2    Oswald, I.P.3
  • 18
    • 0029151623 scopus 로고
    • Possible mechanism involving T-lymphocyte response to nonstructural protein 3 in viral clearance in acute hepatitis C virus infection
    • Diepolder HM, Zachoval R, Hoffmann RM, et al. Possible mechanism involving T-lymphocyte response to nonstructural protein 3 in viral clearance in acute hepatitis C virus infection. Lancet 1995;346:1006-7.
    • (1995) Lancet , vol.346 , pp. 1006-1007
    • Diepolder, H.M.1    Zachoval, R.2    Hoffmann, R.M.3
  • 19
    • 10244225383 scopus 로고    scopus 로고
    • Different clinical behaviors of acute hepatitis C virus infection are associated with different vigor of the anti-viral cell-mediated immune response
    • Missale G, Bertoni R, Lamonaca V, et al. Different clinical behaviors of acute hepatitis C virus infection are associated with different vigor of the anti-viral cell-mediated immune response. J Clin Invest 1996;98:706-14.
    • (1996) J Clin Invest , vol.98 , pp. 706-714
    • Missale, G.1    Bertoni, R.2    Lamonaca, V.3
  • 20
    • 0030053266 scopus 로고    scopus 로고
    • Clinical evaluation of a single reaction, diagnostic polymerase chain reaction assay for the detection of hepatitis C virus RNA
    • Gerken G, Pontisso P, Roggenorf M, et al. Clinical evaluation of a single reaction, diagnostic polymerase chain reaction assay for the detection of hepatitis C virus RNA. J Hepatol 1996;24:33-7.
    • (1996) J Hepatol , vol.24 , pp. 33-37
    • Gerken, G.1    Pontisso, P.2    Roggenorf, M.3
  • 21
    • 0029147455 scopus 로고
    • Induction of T-helper cell response to hepatitis B core antigen in chronic hepatitis B: A major factor in activation of the host immune response to the hepatitis B virus
    • Marinos G, Torre F, Chokshi S, et al. Induction of T-helper cell response to hepatitis B core antigen in chronic hepatitis B: a major factor in activation of the host immune response to the hepatitis B virus. Hepatology 1995;22:1040-9.
    • (1995) Hepatology , vol.22 , pp. 1040-1049
    • Marinos, G.1    Torre, F.2    Chokshi, S.3
  • 22
    • 0024563654 scopus 로고
    • Interferon production in patients infected with HFV-1
    • Rossol S, Voth R, Laubenstein HP, et al. Interferon production in patients infected with HFV-1. J Infect Dis 1989;159: 815-21.
    • (1989) J Infect Dis , vol.159 , pp. 815-821
    • Rossol, S.1    Voth, R.2    Laubenstein, H.P.3
  • 23
    • 0029811057 scopus 로고    scopus 로고
    • T and B-cell responses to different hepatitis C virus antigens in patients with chronic hepatitis C infection and in healthy anti-hepatitis C virus-positive blood donors without viremia
    • Lechmann M, Ihlenfeldt H, G., Braunschweiger I, et al. T and B-cell responses to different hepatitis C virus antigens in patients with chronic hepatitis C infection and in healthy anti-hepatitis C virus-positive blood donors without viremia. Hepatology 1996;24:790-5.
    • (1996) Hepatology , vol.24 , pp. 790-795
    • Lechmann, M.1    Ihlenfeldt, H.G.2    Braunschweiger, I.3
  • 24
    • 0029838758 scopus 로고    scopus 로고
    • The hepatitis B virus persists for decades after patients' recovery from acute viral hepatitis despite active maintenance of a cytotoxic T- lymphocyte response
    • Rehermann B, Ferrari C, Pasquinelli C, et al. The hepatitis B virus persists for decades after patients' recovery from acute viral hepatitis despite active maintenance of a cytotoxic T-lymphocyte response. Nat Med 1996;2:1104-8.
    • (1996) Nat Med , vol.2 , pp. 1104-1108
    • Rehermann, B.1    Ferrari, C.2    Pasquinelli, C.3
  • 25
    • 9544232506 scopus 로고    scopus 로고
    • Long-lasting memory T cell responses following self-limited acute hepatitis B
    • Penna A, Artini M, Cavalli A, et al. Long-lasting memory T cell responses following self-limited acute hepatitis B. J Clin Invest 1996;98:1185-94.
    • (1996) J Clin Invest , vol.98 , pp. 1185-1194
    • Penna, A.1    Artini, M.2    Cavalli, A.3
  • 26
    • 0028047191 scopus 로고
    • Hepatitis B virus persistence after recovery from acute viral hepatitis
    • Michalak TI, Pasquinelli C, Guilhot S, et al. Hepatitis B virus persistence after recovery from acute viral hepatitis. J Clin Invest. 1994;93:230-9.
    • (1994) J Clin Invest. , vol.93 , pp. 230-239
    • Michalak, T.I.1    Pasquinelli, C.2    Guilhot, S.3
  • 27
    • 0031902847 scopus 로고    scopus 로고
    • Clinical significance of intrahepatic hepatitis C virus levels in patients with chronic HCV infection
    • Haydon GH, Jarvis LM, Blair CS, et al. Clinical significance of intrahepatic hepatitis C virus levels in patients with chronic HCV infection. Gut 1998;42:570-5.
    • (1998) Gut , vol.42 , pp. 570-575
    • Haydon, G.H.1    Jarvis, L.M.2    Blair, C.S.3
  • 28
    • 0023030604 scopus 로고
    • Protection against yellow fever in monkeys by immunization with yellow fever virus nonstructural protein NS1
    • Schlesinger JJ, Brandriss MW, Cropp CB, et al. Protection against yellow fever in monkeys by immunization with yellow fever virus nonstructural protein NS1. J Virol 1986;60; 1153-5.
    • (1986) J Virol , vol.60 , pp. 1153-1155
    • Schlesinger, J.J.1    Brandriss, M.W.2    Cropp, C.B.3
  • 29
    • 0026032950 scopus 로고
    • Structural proteins of hog cholera virus expressed by vaccinia virus: Further characterization and induction of protective immunity
    • Rumenapf T, Stark R, Meyers G, et al. Structural proteins of hog cholera virus expressed by vaccinia virus: further characterization and induction of protective immunity. J Virol 1991;65:589-97.
    • (1991) J Virol , vol.65 , pp. 589-597
    • Rumenapf, T.1    Stark, R.2    Meyers, G.3
  • 30
    • 0001420954 scopus 로고
    • Prevention of HCV infection in chimpanzees by hyperimmune serum against the hypervariable region 1 (HVR1): Emergence of neutralization escape mutants in vivo
    • Farci P, Shimoda A, Wong D, et al. Prevention of HCV infection in chimpanzees by hyperimmune serum against the hypervariable region 1 (HVR1): emergence of neutralization escape mutants in vivo [abstract]. Hepatology 1995;22:220A.
    • (1995) Hepatology , vol.22
    • Farci, P.1    Shimoda, A.2    Wong, D.3
  • 31
    • 0029870811 scopus 로고    scopus 로고
    • Quantitative analysis of antibody to hepatitis C virus envelope 2 glycoprotein in patients with chronic hepatitis C virus infection
    • Yuki N, Hayashi N, Kasahara A, et al. Quantitative analysis of antibody to hepatitis C virus envelope 2 glycoprotein in patients with chronic hepatitis C virus infection. Hepatology 1996;23:947-52.
    • (1996) Hepatology , vol.23 , pp. 947-952
    • Yuki, N.1    Hayashi, N.2    Kasahara, A.3
  • 32
    • 2442754632 scopus 로고
    • Prognosis of long-term resolvement from hepatitis C virus infection by E1 antibody monitoring
    • Maertens G, Barlet V, Zarski J-P, et al. Prognosis of long-term resolvement from hepatitis C virus infection by E1 antibody monitoring [abstract]. Hepatohgy 1995;22: 355A.
    • (1995) Hepatohgy , vol.22
    • Maertens, G.1    Barlet, V.2    Zarski, J.-P.3
  • 33
    • 0027319205 scopus 로고
    • Compartmentalization of T lymphocytes to the site of disease: Intrahepatic CD4+ T cells specific for the protein NS4 of hepatitis C virus in patients with chronic hepatitis C
    • Minutello MA, Pileri P, Unutmaz D, et al. Compartmentalization of T lymphocytes to the site of disease: intrahepatic CD4+ T cells specific for the protein NS4 of hepatitis C virus in patients with chronic hepatitis C. J Exp Med 1993; 178:17-25.
    • (1993) J Exp Med , vol.178 , pp. 17-25
    • Minutello, M.A.1    Pileri, P.2    Unutmaz, D.3
  • 34
    • 0028915795 scopus 로고
    • Association between an MHC class II allele and clearance of hepatitis B virus in the Gambia
    • Thursz MR, Kwiatkowski D, Allsopp CE, et al. Association between an MHC class II allele and clearance of hepatitis B virus in the Gambia. N Engl J Med 1995;332:1065-9.
    • (1995) N Engl J Med , vol.332 , pp. 1065-1069
    • Thursz, M.R.1    Kwiatkowski, D.2    Allsopp, C.E.3
  • 35
    • 0032146913 scopus 로고    scopus 로고
    • Association between HLA Class II genotype and spontaneous clearance of HCV infection
    • Cramp ME, Carucci P, Underhill J, et al. Association between HLA Class II genotype and spontaneous clearance of HCV infection. J Hepatol 1998;29:207-13.
    • (1998) J Hepatol , vol.29 , pp. 207-213
    • Cramp, M.E.1    Carucci, P.2    Underhill, J.3
  • 36
    • 0030031273 scopus 로고    scopus 로고
    • Molecular medicine series: DNA vaccines
    • McDonnell WM, Askari FK. Molecular medicine series: DNA vaccines. N Engl J Med 1996;334:42-5.
    • (1996) N Engl J Med , vol.334 , pp. 42-45
    • McDonnell, W.M.1    Askari, F.K.2
  • 37
    • 16944363710 scopus 로고    scopus 로고
    • Protection of chimpanzees from high-dose heterologous HFV-1 challenge by DNA vaccination
    • Boyer JD, Ugen KE, Wang B, et al. Protection of chimpanzees from high-dose heterologous HFV-1 challenge by DNA vaccination. Nat Med 1997;3:526-32.
    • (1997) Nat Med , vol.3 , pp. 526-532
    • Boyer, J.D.1    Ugen, K.E.2    Wang, B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.