Paediatric brain tumours: An embryological perspective

Child's Nervous System

Volumn 16, Issue 5, 2000, Pages 261-267

  Scotting, Paul John ^a   Thompson, Samantha Lee ^a   Punt, Jonathan Arthur Gilbert ^a   Walker, David Austin ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

Central nervous system; Medulloblastoma; Paediatric tumours; Transcription factors, patched

Indexed keywords

GENE PRODUCT; HELIX LOOP HELIX PROTEIN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR;

BASAL CELL NEVUS SYNDROME; BRAIN MATURATION; BRAIN TUMOR; CELL DIFFERENTIATION; CELL TYPE; CHILDHOOD CANCER; EMBRYO DEVELOPMENT; GENE MUTATION; HUMAN; MEDULLOBLASTOMA; NEUROECTODERM TUMOR; PRIORITY JOURNAL; REVIEW;

EID: 0034080249     PISSN: 02567040     EISSN: None     Source Type: Journal    
DOI: 10.1007/s003810050511     Document Type: Review

References (34)

1. Blaschuk K, French-Constant C (1998) Notch is tops in the developing brain. Curr Biol 8:R334-R337
2. Calof AL (1995) Intrinsic and extrinsic factors regulating vertebrate neurogensis. Curr Opin Neurobiol 5:19-27
3. Cohen ME, Duffner P (eds) (1994) Brain tumors in children: principles of diagnosis and treatment, 2nd edn. Raven Press, New York
4. Doe C (1996) Asymmetric cell division and neurogenesis. Curr Opin Genet Dev 6:562-566
5. Giangaspero F, Bigner SH, Giordana MT, Kleihues P, Trojanowski JQ (1997) Medulloblastoma. In: Kleihues P, Cavenee WK (eds) Pathology and genetics of tumours of the nervous system. Oxford University Press, Oxford, pp 96-103
6. Gilbert SF (1994) Developmental biology, 4th edn. Sinaur Associates, Sunderland
7. Goodrich L, Milenkovic L, Higgins K, Scott M (1997) Altered neural cell fates and medulloblastoma in mouse patched mutants. Science 277:1109-1113
8. Hahn H, Wicking C, Zaphiropoulos P, Gailani M, Shanley S, Chidambaram A, Vorechovsky I, Holmberg E, Unden A. Gillies S, Negus K, Smyth I, Pressman C. Leffell D, Gerrard B, Goldstein A, Dean M, Toftgard R, Chenevix-Trench G, Wainwright B, Bale A (1996) Mutations in the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome. Cell 85:841-851
9. Henrique D, Hirsinger E, Adam J, LeRoux I, Pourquie O, Ish-Horowicz D, Lewis J (1997) Maintainance of neuroepithelial progenitor cells by delata-notch signalling in the embryonic chick retina. Curr Biol 7:661-670
10. Hoppe-Hirsch E, Brunet L, Laroussinie F, Cinalli G, Pierre-Kahn A, Renier D, Sainte-Rose C, Hirsch JF (1995) Intellectual outcome in children with malig-nant tumours of the posterior fossa: influence of the field of irradiation and quality of surgery. Child's Nerv Syst 11:340-345
11. Ingham P (1998) The patched gene in development and cancer Curr Opin Genet Dev 8:88-94
12. Johnson R, Rothman A, Xie J, Goodrich L, Bare J, Bonifas J, Quinn A, Myers R, Cox D, Epstein EH Jr, Scott M (1996) Human homolog of patched, a candidate gene for the basal cell nevus syndrome. Science 272:1668-1671
13. Kageyama R, Nakanishi S (1997) Helix-loop-helix factors in growth and differentiation of the vertebrate nervous system. Curr Opin Genet Dev 7:659-665
14. Lewis J (1996) Neurogenic genes and vertebrate neurogenesis. Curr Opin Neurobiol 6:3-10
15. Murone M, Rosenthal A, Sauvage F de (1999) Sonic hedgehog signalling by the patched-smoothened receptor complex. Curr Biol 9:76-84
16. Oro A, Higgins K, Hu Z, Bonifas J, Epstein E Jr, Scott M (1997) Basal cell carcinomas in mice overexpressing sonic hedgehog. Science 276:817-821
17. Perez S, Rebelo S, Anderson D (1999) Early specification of sensory neuron fate revealed by expression and function of neurogenins in the chick embryo. Development 126:1715-1728
18. Pietsch T, Waha A, Koch A, Kraus J, Albrecht S, Tonn J, Sorensen N, Berthold F, Henk B, Schmandt N, Wolf H, Diemling A von, Wainwright B, Chenevix-Trench G, Wiestler O, Wicking C (1997) Medulloblastomas of the desmoplastic varient carry mutations in the human homologue of Drosophila patched. Cancer Res 57:2085-2088
19. Raffel C, Jenkins R, Frederick L, Hebrink D, Alderete B, Fults D, James C (1997) Sporadic medulloblastomas contain PTCH mutations. Cancer Res 57:842-845
20. Rex M, Orme A, Uwanogho D, Tointon K, Wigmore P, Sharpe P, Scotting P (1997) Dynamic expression of the chicken Sox2 and Sox3 genes in ectoderm induced to form neural tissue. Dev Dyn 209:323-332
21. Rorke LB (1999) Pathology of brain and spinal cord tumors. In: Choux M, Di Rocco C, Hockley A, Walker M (eds) Pediatric neurosurgery. Churchill Livingstone, London, pp 396-426
22. Rostomily R, Bermingham-McDonough O, Berger M, Tapscott S, Reh T, Olson J (1997) Expression of neurogenic basic helix-loop-helix genes in primitive neuroectodermal tumours. Cancer Res 57:3526-3531
23. Scotting P, Rex M (1996) Transcription factors in early development of the central nervous system. Neuropathol Appl Neurobiol 22:469-181
24. Shalet SM, Clayton PE, Price DA (1988) Growth and pituitary function in children treated for brain tumours or acute lymphoblastic leukaemia. Horm Res 30:53-61
25. Torii M, Matsuzaki F, Osumi N, Kaibucji K, Nakamura S, Casarosa S, Guillemot F, Nakafuku M (1999) Transcription factors Mash-1 and Prox-1 deliniate early steps in differentiation of neural stem cells in the developing central nervous system. Development 126:443-456
26. Trojanowski J, Tohyama T, Lee V (1992) Medulloblastomas and related primitive neuroectodermal brain tumours of childhood recapitulate molecular milestones in the maturation of neuroblasts. Mol Chem Neuropathol 17:121-135
27. Uwanogho D, Rex M, Cartwright E, Pearl G, Scotting PJ, Sharpe PT (1995) Embryonic expression of the chicken Sox2, Sox3 and Sox11 genes suggests an interactive role in neuronal development. Mech Dev 49:23-36
28. Van Calenbergh F, D'Haen B, Dom R, Menten J, Plets C (1999) Secondary supratentorial anaplastic astrocytoma following treatment of medulloblastoma. Eur J Paediatr Neurol 3:177-180
29. Vorechovsky I, Tingby O, Hartman M, Stomberg B, Nister M, Collins V, Toftgard R (1997) Somatic mutations in the human homologue of drosphila patched in primitive neuroectodermal tumours. Oncogene 15:361-366
30. Walker DA (1999) Chemotherapy in brain and spinal tumors. In: Choux M, Di Rocco C, Hockley A, Walker M (eds) Pediatric neurosurgery. Churchill Livingstone, London, pp 795-824
31. Wallace V (1999) Purkinje-cell-derived sonic hedgehog regulates granule neuron precursor cell proliferation in the developing mouse cerebellum. Curr Biol 9:445-448
32. Wechsler-Reya R, Scott M (1999) Control of neuronal precursor proliferation in the cerebellum by sonic hedgehog. Neuron 22:103-114
33. Wolter M, Reifenberger J, Sommer C, Ruzicka T, Reifenberger G (1997) Mutations in the human homologue of the Drosophila segment polarity gene patched (PTCH) in sporadic basal cell carcinomas of the skin and primitive neuroectodermal tumors of the central nervous system. Cancer Res 57:2581-2585
34. Xie J, Murone M, Luoh S-M, Ryan A, Gu Q, Zhang C, Bonifas J, Lam C-W, Hynes M, Goddard A, Rosenthal A, Epstein E Jr, Sauvage F de (1998) Activating smoothened mutations in sporadic basal-cell carcinoma. Nature 391:90-92