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Volumn 211, Issue 3-4, 2000, Pages 140-150

Novel insights into intermediate-filament function from studies of transgenic and knockout mice

Author keywords

Animal model; Cytoskeleton; Intermediate filaments; Keratins; Transgenic mice

Indexed keywords

CYTOSKELETON; DESMIN; GENE REPLACEMENT; INTERMEDIATE FILAMENT; KERATIN; KNOCKOUT MOUSE; MECHANICAL STRESS; MUTATIONAL ANALYSIS; POINT MUTATION; PROTEIN FUNCTION; TRANSGENIC MOUSE;

EID: 0034078564     PISSN: 0033183X     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF01304482     Document Type: Article
Times cited : (28)

References (86)
  • 1
    • 0028836521 scopus 로고
    • Expression of an epidermal keratin protein in liver of Iransgenic mice causes structural and functional abnormalities
    • Albers KM, Davis FE, Perrone TN, Lee EY, Liu Y, Vore M (1995) Expression of an epidermal keratin protein in liver of Iransgenic mice causes structural and functional abnormalities. J Cell Biol 128: 157-169
    • (1995) J Cell Biol , vol.128 , pp. 157-169
    • Albers, K.M.1    Davis, F.E.2    Perrone, T.N.3    Lee, E.Y.4    Liu, Y.5    Vore, M.6
  • 2
    • 0030721040 scopus 로고    scopus 로고
    • Targeted inactivation of plectin reveals essential function in maintaining the integrity of skin, muscle, and heart cytoarchitecture
    • Andrä K, Lassmann H, Bittner R, Shorny S, Fassler R, Propst F, Wiche G (1997) Targeted inactivation of plectin reveals essential function in maintaining the integrity of skin, muscle, and heart cytoarchitecture. Genes Dev 11: 3143-3156
    • (1997) Genes Dev , vol.11 , pp. 3143-3156
    • Andrä, K.1    Lassmann, H.2    Bittner, R.3    Shorny, S.4    Fassler, R.5    Propst, F.6    Wiche, G.7
  • 3
    • 0027227464 scopus 로고
    • Mid-gestational lethality in mice lacking keratin 8
    • Baribault H, Price J, Miyai K, Oshima RG (1993) Mid-gestational lethality in mice lacking keratin 8. Genes Dev 7: 1191-1202 - Penner J, Iozzo RV, Wilson HM (1994) Colorectal hyperplasia and inflammation in keratin 8-deficient FVB/N mice. Genes Dev 8: 2964-2973
    • (1993) Genes Dev , vol.7 , pp. 1191-1202
    • Baribault, H.1    Price, J.2    Miyai, K.3    Oshima, R.G.4
  • 4
    • 0028607055 scopus 로고
    • Colorectal hyperplasia and inflammation in keratin 8-deficient FVB/N mice
    • Baribault H, Price J, Miyai K, Oshima RG (1993) Mid-gestational lethality in mice lacking keratin 8. Genes Dev 7: 1191-1202 - Penner J, Iozzo RV, Wilson HM (1994) Colorectal hyperplasia and inflammation in keratin 8-deficient FVB/N mice. Genes Dev 8: 2964-2973
    • (1994) Genes Dev , vol.8 , pp. 2964-2973
    • Penner, J.1    Iozzo, R.V.2    Wilson, H.M.3
  • 5
    • 0029750269 scopus 로고    scopus 로고
    • A transgenic mouse model that recapitulates the clinical features of both neonatal and adult forms of the skin disease epidermolytic hyperkeralosis
    • Bickenbach JR, Longley MA, Bundman DS, Dominey AM, Bowden PE, Rothnagel JA, Roop DR (1996) A transgenic mouse model that recapitulates the clinical features of both neonatal and adult forms of the skin disease epidermolytic hyperkeralosis. Differentiation 61: 129-139
    • (1996) Differentiation , vol.61 , pp. 129-139
    • Bickenbach, J.R.1    Longley, M.A.2    Bundman, D.S.3    Dominey, A.M.4    Bowden, P.E.5    Rothnagel, J.A.6    Roop, D.R.7
  • 7
    • 0032478181 scopus 로고    scopus 로고
    • A highly conserved lysine residue on the head domain of type II keratins is essential for the attachment of keratin intermediate filaments to the cornified cell envelope through isopeptide crosslinking by transglutaminases
    • Candi E, Tarcsa E, Digiovanna JJ, Compton JG, Elias PM, Marekov LN, Steinert PM (1998) A highly conserved lysine residue on the head domain of type II keratins is essential for the attachment of keratin intermediate filaments to the cornified cell envelope through isopeptide crosslinking by transglutaminases. Proc Natl Acad Sci USA 95: 2067-2072
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 2067-2072
    • Candi, E.1    Tarcsa, E.2    Digiovanna, J.J.3    Compton, J.G.4    Elias, P.M.5    Marekov, L.N.6    Steinert, P.M.7
  • 8
    • 0028004289 scopus 로고
    • Mice lacking vimentin develop and reproduce without an obvious phenotype
    • Colucci-Guyon E, Portier MM, Dunia I, Paulin D, Pournin S, Babinet C (1994) Mice lacking vimentin develop and reproduce without an obvious phenotype. Cell 79: 679-694 - Gimenez YR, Maurice T, Babinet C, Privat A (1998) Cerebellar defect and impaired motor coordination in mice lacking vimentin. Glia 25: 33-43
    • (1994) Cell , vol.79 , pp. 679-694
    • Colucci-Guyon, E.1    Portier, M.M.2    Dunia, I.3    Paulin, D.4    Pournin, S.5    Babinet, C.6
  • 9
    • 0032889664 scopus 로고    scopus 로고
    • Cerebellar defect and impaired motor coordination in mice lacking vimentin
    • Colucci-Guyon E, Portier MM, Dunia I, Paulin D, Pournin S, Babinet C (1994) Mice lacking vimentin develop and reproduce without an obvious phenotype. Cell 79: 679-694 - Gimenez YR, Maurice T, Babinet C, Privat A (1998) Cerebellar defect and impaired motor coordination in mice lacking vimentin. Glia 25: 33-43
    • (1998) Glia , vol.25 , pp. 33-43
    • Gimenez, Y.R.1    Maurice, T.2    Babinet, C.3    Privat, A.4
  • 10
    • 0030455978 scopus 로고    scopus 로고
    • Human keratin diseases: Hereditary fragility of specific epithelial tissues
    • Corden LD, McLean WH (1996) Human keratin diseases: hereditary fragility of specific epithelial tissues. Exp Dermatol 5: 297-307
    • (1996) Exp Dermatol , vol.5 , pp. 297-307
    • Corden, L.D.1    McLean, W.H.2
  • 11
    • 0027465098 scopus 로고
    • Progressive neuronopathy in transgenic mice expressing the human neurofilament heavy gene: A mouse model of amyotrophic lateral sclerosis
    • Coté F, Collard JF, Julien JP (1993) Progressive neuronopathy in transgenic mice expressing the human neurofilament heavy gene: a mouse model of amyotrophic lateral sclerosis. Cell 73: 35-46
    • (1993) Cell , vol.73 , pp. 35-46
    • Coté, F.1    Collard, J.F.2    Julien, J.P.3
  • 12
    • 0023006055 scopus 로고
    • Cytoskeleton in liver diseases
    • Denk H, Lackinger E (1986) Cytoskeleton in liver diseases. Semin Liver Dis 6: 199-211
    • (1986) Semin Liver Dis , vol.6 , pp. 199-211
    • Denk, H.1    Lackinger, E.2
  • 14
    • 0032482231 scopus 로고    scopus 로고
    • Absence of the mid-sized neurofilament subunit decreases axonal calibers, levels of light neurofilament (NF-L), and neurofilament content
    • Elder GA, Friedrich VL Jr, Bosco P, Kang C, Gourov A, Tu PH, Lee VM, Lazzarini RA (1998a) Absence of the mid-sized neurofilament subunit decreases axonal calibers, levels of light neurofilament (NF-L), and neurofilament content. J Cell Biol 141: 727-739 - Kang C, Bosco P, Gourov A, Tu PH, Zhang B, Lee VM, Lazzarini RA (1998b) Requirement of heavy neurofilament subunit in the development of axons with large calibers. J Cell Biol 143: 195-205
    • (1998) J Cell Biol , vol.141 , pp. 727-739
    • Elder, G.A.1    Friedrich V.L., Jr.2    Bosco, P.3    Kang, C.4    Gourov, A.5    Tu, P.H.6    Lee, V.M.7    Lazzarini, R.A.8
  • 15
    • 0032487502 scopus 로고    scopus 로고
    • Requirement of heavy neurofilament subunit in the development of axons with large calibers
    • Elder GA, Friedrich VL Jr, Bosco P, Kang C, Gourov A, Tu PH, Lee VM, Lazzarini RA (1998a) Absence of the mid-sized neurofilament subunit decreases axonal calibers, levels of light neurofilament (NF-L), and neurofilament content. J Cell Biol 141: 727-739 - Kang C, Bosco P, Gourov A, Tu PH, Zhang B, Lee VM, Lazzarini RA (1998b) Requirement of heavy neurofilament subunit in the development of axons with large calibers. J Cell Biol 143: 195-205
    • (1998) J Cell Biol , vol.143 , pp. 195-205
    • Kang, C.1    Bosco, P.2    Gourov, A.3    Tu, P.H.4    Zhang, B.5    Lee, V.M.6    Lazzarini, R.A.7
  • 16
    • 0028261670 scopus 로고
    • Neurofilament-deficient axons and perikaryal aggregates in viable transgenic mice expressing a neurofilament-beta-galactosidase fusion protein
    • Eyer J, Peterson A (1994) Neurofilament-deficient axons and perikaryal aggregates in viable transgenic mice expressing a neurofilament-beta-galactosidase fusion protein. Neuron 12: 389-405
    • (1994) Neuron , vol.12 , pp. 389-405
    • Eyer, J.1    Peterson, A.2
  • 17
    • 0028287112 scopus 로고
    • Intermediate filaments and disease: Mutations that cripple cell strength
    • Fuchs E, Weber K (1994) Intermediate filaments and disease: mutations that cripple cell strength. J Cell Biol 125: 511-516 - Esteves RA, Coulombe PA (1992) Transgenic mice expressing a mutant keratin 10 gene reveal the likely genetic basis for epidermolytic hyperkeratosis. Proc Natl Acad Sci USA 89: 6906-6910
    • (1994) J Cell Biol , vol.125 , pp. 511-516
    • Fuchs, E.1    Weber, K.2
  • 18
    • 0026725118 scopus 로고
    • Transgenic mice expressing a mutant keratin 10 gene reveal the likely genetic basis for epidermolytic hyperkeratosis
    • Fuchs E, Weber K (1994) Intermediate filaments and disease: mutations that cripple cell strength. J Cell Biol 125: 511-516 - Esteves RA, Coulombe PA (1992) Transgenic mice expressing a mutant keratin 10 gene reveal the likely genetic basis for epidermolytic hyperkeratosis. Proc Natl Acad Sci USA 89: 6906-6910
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 6906-6910
    • Esteves, R.A.1    Coulombe, P.A.2
  • 20
    • 0029940557 scopus 로고    scopus 로고
    • Gene-targeting studies of mammalian behavior: Is it the mutation or the background genotype?
    • Erratum, 19: 271
    • Gerlai R (1996) Gene-targeting studies of mammalian behavior: is it the mutation or the background genotype? Trends Neurosci 19: 177-181 (Erratum, 19: 271) - Williams SP, Cairns B, Van Bruggen N, Moran P, Shih A, Caras I, Sauer H, Phillips HS, Winslow JW (1998) Protein targeting in the analysis of learning and memory: a potential alternative to gene targeting. Exp Brain Res 123: 24-35
    • (1996) Trends Neurosci , vol.19 , pp. 177-181
    • Gerlai, R.1
  • 21
    • 15144343496 scopus 로고    scopus 로고
    • Protein targeting in the analysis of learning and memory: A potential alternative to gene targeting
    • Gerlai R (1996) Gene-targeting studies of mammalian behavior: is it the mutation or the background genotype? Trends Neurosci 19: 177-181 (Erratum, 19: 271) - Williams SP, Cairns B, Van Bruggen N, Moran P, Shih A, Caras I, Sauer H, Phillips HS, Winslow JW (1998) Protein targeting in the analysis of learning and memory: a potential alternative to gene targeting. Exp Brain Res 123: 24-35
    • (1998) Exp Brain Res , vol.123 , pp. 24-35
    • Williams, S.P.1    Cairns, B.2    Van Bruggen, N.3    Moran, P.4    Shih, A.5    Caras, I.6    Sauer, H.7    Phillips, H.S.8    Winslow, J.W.9
  • 24
    • 0028878797 scopus 로고
    • Mice devoid of the glial fibrillary acidic protein develop normally and are susceptible to scrapie prions
    • Gomi H, Yokoyama T, Fujimoto K, Ikeda T, Katoh A, Itoh T, Itohara S (1995) Mice devoid of the glial fibrillary acidic protein develop normally and are susceptible to scrapie prions. Neuron 14: 29-41
    • (1995) Neuron , vol.14 , pp. 29-41
    • Gomi, H.1    Yokoyama, T.2    Fujimoto, K.3    Ikeda, T.4    Katoh, A.5    Itoh, T.6    Itohara, S.7
  • 25
    • 0029066406 scopus 로고
    • Gene targeting of BPAG1: Abnormalities in mechanical strength and cell migration in stratified epithelia and neurologic degeneration
    • Guo L, Degenstein L, Dowling J, Yu QC, Wollmann R, Perman B, Fuchs E (1995) Gene targeting of BPAG1: abnormalities in mechanical strength and cell migration in stratified epithelia and neurologic degeneration. Cell 81: 233-243
    • (1995) Cell , vol.81 , pp. 233-243
    • Guo, L.1    Degenstein, L.2    Dowling, J.3    Yu, Q.C.4    Wollmann, R.5    Perman, B.6    Fuchs, E.7
  • 26
    • 0022348539 scopus 로고
    • Pair formation and promiscuity of cytokeratins: Formation in vitro of heterotypic complexes and intermediate-sized filaments by homologous and heterologous recombinations of purified polypeptides
    • Hatzfeld M, Franke WW (1985) Pair formation and promiscuity of cytokeratins: formation in vitro of heterotypic complexes and intermediate-sized filaments by homologous and heterologous recombinations of purified polypeptides. J Cell Biol 101: 1826-1841
    • (1985) J Cell Biol , vol.101 , pp. 1826-1841
    • Hatzfeld, M.1    Franke, W.W.2
  • 28
    • 0032053588 scopus 로고    scopus 로고
    • Intermediate filament assembly: Fibrillogenesis is driven by decisive dimer-dimer interactions
    • Herrmann H, Aebi U (1998) Intermediate filament assembly: fibrillogenesis is driven by decisive dimer-dimer interactions. Curr Opin Struct Biol 8: 177-185 - Harris JR (eds) (1998) Intermediate filaments. Plenum, New York
    • (1998) Curr Opin Struct Biol , vol.8 , pp. 177-185
    • Herrmann, H.1    Aebi, U.2
  • 29
    • 0032053588 scopus 로고    scopus 로고
    • Plenum, New York
    • Herrmann H, Aebi U (1998) Intermediate filament assembly: fibrillogenesis is driven by decisive dimer-dimer interactions. Curr Opin Struct Biol 8: 177-185 - Harris JR (eds) (1998) Intermediate filaments. Plenum, New York
    • (1998) Intermediate Filaments
    • Harris, J.R.1
  • 30
    • 0021167918 scopus 로고
    • Fine structural observations of neurofilamentous changes in amyotrophic lateral sclerosis
    • Hirano A, Donnenfeld H, Sasaki S, Nakano I (1984) Fine structural observations of neurofilamentous changes in amyotrophic lateral sclerosis. J Neuropathol Exp Neurol 43: 461-470
    • (1984) J Neuropathol Exp Neurol , vol.43 , pp. 461-470
    • Hirano, A.1    Donnenfeld, H.2    Sasaki, S.3    Nakano, I.4
  • 31
    • 0032487437 scopus 로고    scopus 로고
    • Gene targeting studies begin to reveal the function of neurofilament proteins
    • Erratum, 143: 1142
    • Hirokawa N, Takeda S (1998) Gene targeting studies begin to reveal the function of neurofilament proteins. J Cell Biol 143: 1-4 (Erratum, 143: 1142)
    • (1998) J Cell Biol , vol.143 , pp. 1-4
    • Hirokawa, N.1    Takeda, S.2
  • 35
    • 0028865145 scopus 로고
    • Chronic hepatitis, hepatocyte fragility, and increased soluble phosphoglycokeratins in transgenic mice expressing a keratin 18 conserved arginine mutant
    • Ku NO, Michie S, Oshima RG, Omary MB (1995) Chronic hepatitis, hepatocyte fragility, and increased soluble phosphoglycokeratins in transgenic mice expressing a keratin 18 conserved arginine mutant. J Cell Biol 131: 1303-1314 - Soetikno RM, Resurreccion EZ, Broome RL, Oshima RG, Omary MB (1996) Susceptibility to hepatotoxicity in transgenic mice that express a dominant-negative human keratin 18 mutant. J Clin Invest 98: 1034-1046 - Resurreccion EZ, Broome RL, Omary MB (1998) Mutation of a major keratin phosphorylation site predisposes to hepatotoxic injury in transgenic mice. J Cell Biol 143: 2023-2032
    • (1995) J Cell Biol , vol.131 , pp. 1303-1314
    • Ku, N.O.1    Michie, S.2    Oshima, R.G.3    Omary, M.B.4
  • 36
    • 0029789008 scopus 로고    scopus 로고
    • Susceptibility to hepatotoxicity in transgenic mice that express a dominant-negative human keratin 18 mutant
    • Ku NO, Michie S, Oshima RG, Omary MB (1995) Chronic hepatitis, hepatocyte fragility, and increased soluble phosphoglycokeratins in transgenic mice expressing a keratin 18 conserved arginine mutant. J Cell Biol 131: 1303-1314 - Soetikno RM, Resurreccion EZ, Broome RL, Oshima RG, Omary MB (1996) Susceptibility to hepatotoxicity in transgenic mice that express a dominant-negative human keratin 18 mutant. J Clin Invest 98: 1034-1046 - Resurreccion EZ, Broome RL, Omary MB (1998) Mutation of a major keratin phosphorylation site predisposes to hepatotoxic injury in transgenic mice. J Cell Biol 143: 2023-2032
    • (1996) J Clin Invest , vol.98 , pp. 1034-1046
    • Soetikno, R.M.1    Resurreccion, E.Z.2    Broome, R.L.3    Oshima, R.G.4    Omary, M.B.5
  • 37
    • 0032576580 scopus 로고    scopus 로고
    • Mutation of a major keratin phosphorylation site predisposes to hepatotoxic injury in transgenic mice
    • Ku NO, Michie S, Oshima RG, Omary MB (1995) Chronic hepatitis, hepatocyte fragility, and increased soluble phosphoglycokeratins in transgenic mice expressing a keratin 18 conserved arginine mutant. J Cell Biol 131: 1303-1314 - Soetikno RM, Resurreccion EZ, Broome RL, Oshima RG, Omary MB (1996) Susceptibility to hepatotoxicity in transgenic mice that express a dominant-negative human keratin 18 mutant. J Clin Invest 98: 1034-1046 - Resurreccion EZ, Broome RL, Omary MB (1998) Mutation of a major keratin phosphorylation site predisposes to hepatotoxic injury in transgenic mice. J Cell Biol 143: 2023-2032
    • (1998) J Cell Biol , vol.143 , pp. 2023-2032
    • Resurreccion, E.Z.1    Broome, R.L.2    Omary, M.B.3
  • 38
  • 39
    • 0029893923 scopus 로고    scopus 로고
    • Cardiovascular lesions and skeletal myopathy in mice lacking desmin
    • Li Z, Colucci GE, Pincon RM, Mericskay M, Pournin S, Paulin D, Babinet C (1996) Cardiovascular lesions and skeletal myopathy in mice lacking desmin. Dev Biol 175: 362-366 - Mericskay M, Agbulut O, Butler BG, Carlsson L, Thornell LE, Babinet C, Paulin D (1997) Desmin is essential for the tensile strength and integrity of myofibrils but not for myogenic commitment, differentiation, and fusion of skeletal muscle. J Cell Biol 139: 129-144
    • (1996) Dev Biol , vol.175 , pp. 362-366
    • Li, Z.1    Colucci, G.E.2    Pincon, R.M.3    Mericskay, M.4    Pournin, S.5    Paulin, D.6    Babinet, C.7
  • 40
    • 0030879081 scopus 로고    scopus 로고
    • Desmin is essential for the tensile strength and integrity of myofibrils but not for myogenic commitment, differentiation, and fusion of skeletal muscle
    • Li Z, Colucci GE, Pincon RM, Mericskay M, Pournin S, Paulin D, Babinet C (1996) Cardiovascular lesions and skeletal myopathy in mice lacking desmin. Dev Biol 175: 362-366 - Mericskay M, Agbulut O, Butler BG, Carlsson L, Thornell LE, Babinet C, Paulin D (1997) Desmin is essential for the tensile strength and integrity of myofibrils but not for myogenic commitment, differentiation, and fusion of skeletal muscle. J Cell Biol 139: 129-144
    • (1997) J Cell Biol , vol.139 , pp. 129-144
    • Mericskay, M.1    Agbulut, O.2    Butler, B.G.3    Carlsson, L.4    Thornell, L.E.5    Babinet, C.6    Paulin, D.7
  • 41
    • 0031964424 scopus 로고    scopus 로고
    • Experimental autoimmune encephalomyelitis in mice lacking glial fibrillary acidic protein is characterized by a more severe clinical course and an infiltrative central nervous system lesion
    • Liedtke W, Edelmann W, Chiu FC, Kucherlapati R, Raine CS (1998) Experimental autoimmune encephalomyelitis in mice lacking glial fibrillary acidic protein is characterized by a more severe clinical course and an infiltrative central nervous system lesion. Am J Pathol 152: 251-259
    • (1998) Am J Pathol , vol.152 , pp. 251-259
    • Liedtke, W.1    Edelmann, W.2    Chiu, F.C.3    Kucherlapati, R.4    Raine, C.S.5
  • 42
    • 0029043889 scopus 로고
    • The basal keratin network of stratified squamous epithelia: Defining K15 function in the absence of K14
    • Lloyd C, Yu QC, Cheng J, Turksen K, Degenstein L, Hutton E, Fuchs E (1995) The basal keratin network of stratified squamous epithelia: defining K15 function in the absence of K14. J Cell Biol 129: 1329-1344
    • (1995) J Cell Biol , vol.129 , pp. 1329-1344
    • Lloyd, C.1    Yu, Q.C.2    Cheng, J.3    Turksen, K.4    Degenstein, L.5    Hutton, E.6    Fuchs, E.7
  • 44
    • 0032242489 scopus 로고    scopus 로고
    • Lessons from keratin transgenic and knockout mice
    • Hermann H, Harris JR (eds). Plenum, New York
    • Magin TM (1998) Lessons from keratin transgenic and knockout mice. In: Hermann H, Harris JR (eds) Intermediate filaments. Plenum, New York, pp 141-172 - Schröder R, Leitgeb S, Wanninger F, Zatloukal K, Grund C, Melton DW (1998) Lessons from keratin 18 knockout mice: formation of novel keratin filaments, secondary loss of keratin 7 and accumulation of liver-specific keratin 8-positive aggregates. J Cell Biol 140: 1441-1451
    • (1998) Intermediate Filaments , pp. 141-172
    • Magin, T.M.1
  • 45
    • 2642684550 scopus 로고    scopus 로고
    • Lessons from keratin 18 knockout mice: Formation of novel keratin filaments, secondary loss of keratin 7 and accumulation of liver-specific keratin 8-positive aggregates
    • Magin TM (1998) Lessons from keratin transgenic and knockout mice. In: Hermann H, Harris JR (eds) Intermediate filaments. Plenum, New York, pp 141-172 - Schröder R, Leitgeb S, Wanninger F, Zatloukal K, Grund C, Melton DW (1998) Lessons from keratin 18 knockout mice: formation of novel keratin filaments, secondary loss of keratin 7 and accumulation of liver-specific keratin 8-positive aggregates. J Cell Biol 140: 1441-1451
    • (1998) J Cell Biol , vol.140 , pp. 1441-1451
    • Schröder, R.1    Leitgeb, S.2    Wanninger, F.3    Zatloukal, K.4    Grund, C.5    Melton, D.W.6
  • 46
    • 0023181424 scopus 로고
    • Changes in keratinocyte maturation during wound healing
    • Mansbridge JN, Knapp AM (1987) Changes in keratinocyte maturation during wound healing. J Invest Dermatol 89: 253-263
    • (1987) J Invest Dermatol , vol.89 , pp. 253-263
    • Mansbridge, J.N.1    Knapp, A.M.2
  • 49
    • 0029738727 scopus 로고    scopus 로고
    • Disruption of muscle architecture and myocardial degeneration in mice lacking desmin
    • Milner DJ, Weitzer G, Tran D, Bradley A, Capetanaki Y (1996) Disruption of muscle architecture and myocardial degeneration in mice lacking desmin. J Cell Biol 134: 1255-1270
    • (1996) J Cell Biol , vol.134 , pp. 1255-1270
    • Milner, D.J.1    Weitzer, G.2    Tran, D.3    Bradley, A.4    Capetanaki, Y.5
  • 50
    • 0020467073 scopus 로고
    • The catalog of human cytokeratins: Patterns of expression in normal epithelia, tumors and cultured cells
    • Moll R, Franke WW, Schiller DL, Geiger B, Krepler R (1982) The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells. Cell 31: 11-24
    • (1982) Cell , vol.31 , pp. 11-24
    • Moll, R.1    Franke, W.W.2    Schiller, D.L.3    Geiger, B.4    Krepler, R.5
  • 52
    • 0023357815 scopus 로고
    • The human mid-size neurofilament subunit: A repeated protein sequence and the relationship of its gene to the intermediate filament gene family
    • Myers MW, Lazzarini RA, Lee VM, Schlaepfer WW, Nelson DL (1987) The human mid-size neurofilament subunit: a repeated protein sequence and the relationship of its gene to the intermediate filament gene family. EMBO J 6: 1617-1626
    • (1987) EMBO J , vol.6 , pp. 1617-1626
    • Myers, M.W.1    Lazzarini, R.A.2    Lee, V.M.3    Schlaepfer, W.W.4    Nelson, D.L.5
  • 53
    • 0029875349 scopus 로고    scopus 로고
    • Myofibrillar myopathy with abnormal foci of desmin positivity I: Light and electron microscopy analysis of 10 cases
    • Nakano S, Engel AG, Waclawik AJ, Emslie SA, Busis NA (1996) Myofibrillar myopathy with abnormal foci of desmin positivity I: light and electron microscopy analysis of 10 cases. J Neuropathol Exp Neurol 55: 549-562
    • (1996) J Neuropathol Exp Neurol , vol.55 , pp. 549-562
    • Nakano, S.1    Engel, A.G.2    Waclawik, A.J.3    Emslie, S.A.4    Busis, N.A.5
  • 55
    • 0027530064 scopus 로고
    • Neurofilament deficiency in quail caused by nonsense mutation in neurofilament-L gene
    • Ohara O, Gahara Y, Miyke T, Teraoka H, Kitamura T (1993) Neurofilament deficiency in quail caused by nonsense mutation in neurofilament-L gene. J Cell Biol 121: 387-395
    • (1993) J Cell Biol , vol.121 , pp. 387-395
    • Ohara, O.1    Gahara, Y.2    Miyke, T.3    Teraoka, H.4    Kitamura, T.5
  • 56
    • 0030955612 scopus 로고    scopus 로고
    • Intermediate filament proteins of the liver: Emerging disease association and functions
    • Omary MB, Ku NO (1997) Intermediate filament proteins of the liver: emerging disease association and functions. Hepatology 25: 1043-1048
    • (1997) Hepatology , vol.25 , pp. 1043-1048
    • Omary, M.B.1    Ku, N.O.2
  • 57
    • 0032563572 scopus 로고    scopus 로고
    • Directed expression of keratin 16 to the progenitor basal cells of transgenic mouse skin delays skin maturation
    • Paladini RD, Coulombe PA (1998) Directed expression of keratin 16 to the progenitor basal cells of transgenic mouse skin delays skin maturation. J Cell Biol 142: 1035-1051 - (1999) The functional diversity of epidermal keratins revealed by the partial rescue of the keratin 14 null phenotype by keratin 16. J Cell Biol 146: 1185-1201
    • (1998) J Cell Biol , vol.142 , pp. 1035-1051
    • Paladini, R.D.1    Coulombe, P.A.2
  • 58
    • 0032824490 scopus 로고    scopus 로고
    • The functional diversity of epidermal keratins revealed by the partial rescue of the keratin 14 null phenotype by keratin 16
    • Paladini RD, Coulombe PA (1998) Directed expression of keratin 16 to the progenitor basal cells of transgenic mouse skin delays skin maturation. J Cell Biol 142: 1035-1051 - (1999) The functional diversity of epidermal keratins revealed by the partial rescue of the keratin 14 null phenotype by keratin 16. J Cell Biol 146: 1185-1201
    • (1999) J Cell Biol , vol.146 , pp. 1185-1201
  • 59
    • 0029012164 scopus 로고
    • Mice lacking glial fibrillary acidic protein display astrocytes devoid of intermediate filaments but develop and reproduce normally
    • Pekny M, Leveen P, Pekna M, Eliasson C, Berthold CH, Westermark B, Betsholtz C (1995) Mice lacking glial fibrillary acidic protein display astrocytes devoid of intermediate filaments but develop and reproduce normally. EMBO J 14: 1590-1598
    • (1995) EMBO J , vol.14 , pp. 1590-1598
    • Pekny, M.1    Leveen, P.2    Pekna, M.3    Eliasson, C.4    Berthold, C.H.5    Westermark, B.6    Betsholtz, C.7
  • 60
    • 0029670060 scopus 로고    scopus 로고
    • Gene targeting at the mouse cytokeratin 10 locus: Severe skin fragility and changes of cytokeratin expression in the epidermis
    • Porter RM, Leitgeb S, Melton DW, Swensson O, Eady RA, Magin TM (1996) Gene targeting at the mouse cytokeratin 10 locus: severe skin fragility and changes of cytokeratin expression in the epidermis. J Cell Biol 132: 925-936 - Reichelt J, Lunny DP, Magin TM, Lane EB (1998a) The relationship between hyperproliferation and epidermal thickening in a mouse model for BCIE. J Invest Dermatol 110: 951-957 - Hutcheson AM, Rugg EL, Quinlan RA, Lane EB (1998b) cDNA cloning, expression and assembly characteristics of mouse keratin 16. J Biol Chem 273: 32265-32272
    • (1996) J Cell Biol , vol.132 , pp. 925-936
    • Porter, R.M.1    Leitgeb, S.2    Melton, D.W.3    Swensson, O.4    Eady, R.A.5    Magin, T.M.6
  • 61
    • 0031808587 scopus 로고    scopus 로고
    • The relationship between hyperproliferation and epidermal thickening in a mouse model for BCIE
    • Porter RM, Leitgeb S, Melton DW, Swensson O, Eady RA, Magin TM (1996) Gene targeting at the mouse cytokeratin 10 locus: severe skin fragility and changes of cytokeratin expression in the epidermis. J Cell Biol 132: 925-936 - Reichelt J, Lunny DP, Magin TM, Lane EB (1998a) The relationship between hyperproliferation and epidermal thickening in a mouse model for BCIE. J Invest Dermatol 110: 951-957 - Hutcheson AM, Rugg EL, Quinlan RA, Lane EB (1998b) cDNA cloning, expression and assembly characteristics of mouse keratin 16. J Biol Chem 273: 32265-32272
    • (1998) J Invest Dermatol , vol.110 , pp. 951-957
    • Reichelt, J.1    Lunny, D.P.2    Magin, T.M.3    Lane, E.B.4
  • 62
    • 0033610836 scopus 로고    scopus 로고
    • cDNA cloning, expression and assembly characteristics of mouse keratin 16
    • Porter RM, Leitgeb S, Melton DW, Swensson O, Eady RA, Magin TM (1996) Gene targeting at the mouse cytokeratin 10 locus: severe skin fragility and changes of cytokeratin expression in the epidermis. J Cell Biol 132: 925-936 - Reichelt J, Lunny DP, Magin TM, Lane EB (1998a) The relationship between hyperproliferation and epidermal thickening in a mouse model for BCIE. J Invest Dermatol 110: 951-957 - Hutcheson AM, Rugg EL, Quinlan RA, Lane EB (1998b) cDNA cloning, expression and assembly characteristics of mouse keratin 16. J Biol Chem 273: 32265-32272
    • (1998) J Biol Chem , vol.273 , pp. 32265-32272
    • Hutcheson, A.M.1    Rugg, E.L.2    Quinlan, R.A.3    Lane, E.B.4
  • 63
    • 0032487499 scopus 로고    scopus 로고
    • Neurofilament-dependent radial growth of motor axons and axonal organization of neurofilaments does not require the neurofilament heavy subunit (NF-H) or its phosphorylation
    • Rao MV, Houseweart MK, Williamson TL, Crawford TO, Folmer J, Cleveland DW (1998) Neurofilament-dependent radial growth of motor axons and axonal organization of neurofilaments does not require the neurofilament heavy subunit (NF-H) or its phosphorylation. J Cell Biol 143: 171-181
    • (1998) J Cell Biol , vol.143 , pp. 171-181
    • Rao, M.V.1    Houseweart, M.K.2    Williamson, T.L.3    Crawford, T.O.4    Folmer, J.5    Cleveland, D.W.6
  • 64
    • 0030817021 scopus 로고    scopus 로고
    • Out of balance: Consequences of a partial keratin 10 knockout
    • Reichelt J, Bauer C, Porter R, Lane E, Magin V (1997) Out of balance: consequences of a partial keratin 10 knockout. J Cell Sci 110: 2175-2186 - Doering T, Schnetz E, Fartasch M, Sandhoff K, Magin TM (1999) Normal ultrastructure, but altered stratum corneum lipid and protein composition in a mouse model for epidermolytic hyperkeratosis. J Invest Dermatol 113: 329-333
    • (1997) J Cell Sci , vol.110 , pp. 2175-2186
    • Reichelt, J.1    Bauer, C.2    Porter, R.3    Lane, E.4    Magin, V.5
  • 65
    • 0032835593 scopus 로고    scopus 로고
    • Normal ultrastructure, but altered stratum corneum lipid and protein composition in a mouse model for epidermolytic hyperkeratosis
    • Reichelt J, Bauer C, Porter R, Lane E, Magin V (1997) Out of balance: consequences of a partial keratin 10 knockout. J Cell Sci 110: 2175-2186 - Doering T, Schnetz E, Fartasch M, Sandhoff K, Magin TM (1999) Normal ultrastructure, but altered stratum corneum lipid and protein composition in a mouse model for epidermolytic hyperkeratosis. J Invest Dermatol 113: 329-333
    • (1999) J Invest Dermatol , vol.113 , pp. 329-333
    • Doering, T.1    Schnetz, E.2    Fartasch, M.3    Sandhoff, K.4    Magin, T.M.5
  • 66
    • 0030795164 scopus 로고    scopus 로고
    • The plakin family: Versatile organizers of cytoskeletal architecture
    • Ruhrherg C, Watt FM (1997) The plakin family: versatile organizers of cytoskeletal architecture. Curr Opin Genet Dev 7: 392-397
    • (1997) Curr Opin Genet Dev , vol.7 , pp. 392-397
    • Ruhrherg, C.1    Watt, F.M.2
  • 70
    • 0031983665 scopus 로고
    • The cytoskeleton in skeletal, cardiac and smooth muscle cells
    • Stromer MH (1988) The cytoskeleton in skeletal, cardiac and smooth muscle cells. Histol Histopathol 13: 283-291
    • (1988) Histol Histopathol , vol.13 , pp. 283-291
    • Stromer, M.H.1
  • 71
    • 0029905020 scopus 로고    scopus 로고
    • A transgenic mouse model with an inducible skin blistering disease phenotype
    • Takahashi K, Coulombe PA (1996) A transgenic mouse model with an inducible skin blistering disease phenotype. Proc Natl Acad Sci USA 93: 14776-14781 - Folmer J, Coulombe PA (1994) Increased expression of keratin 16 causes anomalies in cytoarchitecture and keratinization in transgenic mouse skin. J Cell Biol 127: 505-520
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 14776-14781
    • Takahashi, K.1    Coulombe, P.A.2
  • 72
    • 0028109866 scopus 로고
    • Increased expression of keratin 16 causes anomalies in cytoarchitecture and keratinization in transgenic mouse skin
    • Takahashi K, Coulombe PA (1996) A transgenic mouse model with an inducible skin blistering disease phenotype. Proc Natl Acad Sci USA 93: 14776-14781 - Folmer J, Coulombe PA (1994) Increased expression of keratin 16 causes anomalies in cytoarchitecture and keratinization in transgenic mouse skin. J Cell Biol 127: 505-520
    • (1994) J Cell Biol , vol.127 , pp. 505-520
    • Folmer, J.1    Coulombe, P.A.2
  • 73
    • 0030952913 scopus 로고    scopus 로고
    • Normal tubular regeneration and differentiation of the post-ischemic kidney in mice lacking vimentin
    • Terzi F, Maunoury R, Colucci GE, Babinet C, Federici P, Briand P, Friedlander G (1997a) Normal tubular regeneration and differentiation of the post-ischemic kidney in mice lacking vimentin. Am J Pathol 150: 1361-1371 - Henrion D, Colucci GE, Federici P, Babinet C, Levy BI, Briand P, Friedlander G (1997b) Reduction of renal mass is lethal in mice lacking vimentin: role of endothelin-nitric oxide imbalance. J Clin Invest 100: 1520-1528
    • (1997) Am J Pathol , vol.150 , pp. 1361-1371
    • Terzi, F.1    Maunoury, R.2    Colucci, G.E.3    Babinet, C.4    Federici, P.5    Briand, P.6    Friedlander, G.7
  • 74
    • 0030770392 scopus 로고    scopus 로고
    • Reduction of renal mass is lethal in mice lacking vimentin: Role of endothelin-nitric oxide imbalance
    • Terzi F, Maunoury R, Colucci GE, Babinet C, Federici P, Briand P, Friedlander G (1997a) Normal tubular regeneration and differentiation of the post-ischemic kidney in mice lacking vimentin. Am J Pathol 150: 1361-1371 - Henrion D, Colucci GE, Federici P, Babinet C, Levy BI, Briand P, Friedlander G (1997b) Reduction of renal mass is lethal in mice lacking vimentin: role of endothelin-nitric oxide imbalance. J Clin Invest 100: 1520-1528
    • (1997) J Clin Invest , vol.100 , pp. 1520-1528
    • Henrion, D.1    Colucci, G.E.2    Federici, P.3    Babinet, C.4    Levy, B.I.5    Briand, P.6    Friedlander, G.7
  • 76
    • 0031836071 scopus 로고    scopus 로고
    • Protein phosphatase inhibition in normal and keratin 8/18 assembly-incompetent mouse strains supports a functional role of keratin intermediate filaments in preserving hepatocyte integrity
    • Toivola DM, Omary MB, Ku NO, Peltola O, Baribault H, Eriksson JE (1998) Protein phosphatase inhibition in normal and keratin 8/18 assembly-incompetent mouse strains supports a functional role of keratin intermediate filaments in preserving hepatocyte integrity. Hepatology 28: 116-128
    • (1998) Hepatology , vol.28 , pp. 116-128
    • Toivola, D.M.1    Omary, M.B.2    Ku, N.O.3    Peltola, O.4    Baribault, H.5    Eriksson, J.E.6
  • 77
    • 0020507948 scopus 로고
    • Cessation of cytokeratin expression in a rat hepatoma cell line lacking differentiated functions
    • Venetianer A, Schiller DL, Magin T, Franke WW (1983) Cessation of cytokeratin expression in a rat hepatoma cell line lacking differentiated functions. Nature 305: 730-733
    • (1983) Nature , vol.305 , pp. 730-733
    • Venetianer, A.1    Schiller, D.L.2    Magin, T.3    Franke, W.W.4
  • 79
    • 0031418077 scopus 로고    scopus 로고
    • Axonal and nonneuronal cell responses to spinal cord injury in mice lacking glial fibrillary acidic protein
    • Wang X, Messing A, David S (1997) Axonal and nonneuronal cell responses to spinal cord injury in mice lacking glial fibrillary acidic protein. Exp Neurol 148: 568-576
    • (1997) Exp Neurol , vol.148 , pp. 568-576
    • Wang, X.1    Messing, A.2    David, S.3
  • 80
    • 0031452569 scopus 로고    scopus 로고
    • A proline residue in the alpha-helical rod domain of type I keratin 16 destabilizes keratin heterotetramers
    • Wawersik M, Paladini RD, Noensie E, Coulombe PA (1997) A proline residue in the alpha-helical rod domain of type I keratin 16 destabilizes keratin heterotetramers. J Biol Chem 272: 32557-32565
    • (1997) J Biol Chem , vol.272 , pp. 32557-32565
    • Wawersik, M.1    Paladini, R.D.2    Noensie, E.3    Coulombe, P.A.4
  • 81
    • 0029558009 scopus 로고
    • Cytoskeletal control of myogenesis: A desmin null mutation blocks the myogenic pathway during embryonic stem cell differentiation
    • Weitzer G, Milner DJ, Kim JU, Bradley A, Capetanaki Y (1995) Cytoskeletal control of myogenesis: a desmin null mutation blocks the myogenic pathway during embryonic stem cell differentiation. Dev Biol 172: 422-439
    • (1995) Dev Biol , vol.172 , pp. 422-439
    • Weitzer, G.1    Milner, D.J.2    Kim, J.U.3    Bradley, A.4    Capetanaki, Y.5
  • 82
    • 0029124072 scopus 로고
    • Increasing neurofilament subunit NF-M expression reduces axonal, NF-H inhibits radial growth, and results in neurofilamentous accumulation in motor neurons
    • Wong PC, Marszalek J, Crawford TO, Xu Z, Hsieh ST, Griffin JW, Cleveland DW (1995) Increasing neurofilament subunit NF-M expression reduces axonal, NF-H inhibits radial growth, and results in neurofilamentous accumulation in motor neurons. J Cell Biol 130: 1413-1422
    • (1995) J Cell Biol , vol.130 , pp. 1413-1422
    • Wong, P.C.1    Marszalek, J.2    Crawford, T.O.3    Xu, Z.4    Hsieh, S.T.5    Griffin, J.W.6    Cleveland, D.W.7
  • 84
    • 0025993428 scopus 로고
    • Hereditary hypotrophic axonopathy with neurofilament deficiency in a mutant strain of the Japanese quail
    • Yamasaki H, Itakura C, Mizutani M (1991) Hereditary hypotrophic axonopathy with neurofilament deficiency in a mutant strain of the Japanese quail. Acta Neuropathol 82: 427-434
    • (1991) Acta Neuropathol , vol.82 , pp. 427-434
    • Yamasaki, H.1    Itakura, C.2    Mizutani, M.3
  • 85
    • 0031263931 scopus 로고    scopus 로고
    • Delayed maturation of regenerating myclinated axons in mice lacking neurofilaments
    • Zhu O, Couillard DS, Julien JP (1997) Delayed maturation of regenerating myclinated axons in mice lacking neurofilaments. Exp Neurol 148: 299-316 - Lindenbaum M, Levavasseur F, Jacomy H, Julien JP (1998) Disruption of the NF-H gene increases axonal mierotubule content and velocity of neurofilament transport: relief of axonopathy resulting from the toxin beta, beta′-iminodipropionitrile. J Cell Biol 143: 183-193
    • (1997) Exp Neurol , vol.148 , pp. 299-316
    • Zhu, O.1    Couillard, D.S.2    Julien, J.P.3
  • 86
    • 0032487532 scopus 로고    scopus 로고
    • Disruption of the NF-H gene increases axonal mierotubule content and velocity of neurofilament transport: Relief of axonopathy resulting from the toxin beta, beta′-iminodipropionitrile
    • Zhu O, Couillard DS, Julien JP (1997) Delayed maturation of regenerating myclinated axons in mice lacking neurofilaments. Exp Neurol 148: 299-316 - Lindenbaum M, Levavasseur F, Jacomy H, Julien JP (1998) Disruption of the NF-H gene increases axonal mierotubule content and velocity of neurofilament transport: relief of axonopathy resulting from the toxin beta, beta′-iminodipropionitrile. J Cell Biol 143: 183-193
    • (1998) J Cell Biol , vol.143 , pp. 183-193
    • Lindenbaum, M.1    Levavasseur, F.2    Jacomy, H.3    Julien, J.P.4


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