메뉴 건너뛰기




Volumn 146, Issue 5, 1999, Pages 1185-1201

The functional diversity of epidermal keratins revealed by the partial rescue of the keratin 14 null phenotype by keratin 16

Author keywords

Epidermis; Gene replacement; Hair; Keratin; Transgenic mice

Indexed keywords

COMPLEMENTARY DNA; KERATIN;

EID: 0032824490     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.146.5.1185     Document Type: Article
Times cited : (48)

References (66)
  • 1
    • 0028033095 scopus 로고
    • Ultrastructural identification of basic abnormalities as clues to genetic disorders of the epidermis
    • Anton-Lamprecht, I. 1994. Ultrastructural identification of basic abnormalities as clues to genetic disorders of the epidermis. J. Invest. Dermatol. 103:65-125.
    • (1994) J. Invest. Dermatol. , vol.103 , pp. 65-125
    • Anton-Lamprecht, I.1
  • 3
    • 0027943989 scopus 로고
    • A human keratin 14 "knockout": The absence of K14 leads to severe epidermolysis bullosa simplex and a function for an intermediate filament protein
    • Chan, Y.-M., I. Anton-Lamprecht, Q.C. Yu, A. Jackel, B. Zabel, J.P. Ernst, and E. Fuchs. 1994. A human keratin 14 "knockout": the absence of K14 leads to severe epidermolysis bullosa simplex and a function for an intermediate filament protein. Genes Dev. 8:2574-2587.
    • (1994) Genes Dev. , vol.8 , pp. 2574-2587
    • Chan, Y.-M.1    Anton-Lamprecht, I.2    Yu, Q.C.3    Jackel, A.4    Zabel, B.5    Ernst, J.P.6    Fuchs, E.7
  • 4
    • 0026666391 scopus 로고
    • Characterization of human cytokeratin 2. An epidermal cytoskeletal protein synthesized late during differentiation
    • Collin, C., R. Moll, S. Kubicka, J.P. Ouhayoun, and W.W. Franke. 1992. Characterization of human cytokeratin 2. an epidermal cytoskeletal protein synthesized late during differentiation. Exp. Cell Res. 202:132-141.
    • (1992) Exp. Cell Res. , vol.202 , pp. 132-141
    • Collin, C.1    Moll, R.2    Kubicka, S.3    Ouhayoun, J.P.4    Franke, W.W.5
  • 5
    • 0024523631 scopus 로고
    • Existence of slow-cycling limbal epithelial basal cells that can be preferentially stimulated to proliferate: Implications on epithelial stem cells
    • Cotsarelis, G., S.Z. Cheng, G. Dong, T.T. Sun, and R.M. Lavker. 1989. Existence of slow-cycling limbal epithelial basal cells that can be preferentially stimulated to proliferate: implications on epithelial stem cells. Cell. 57:201-209.
    • (1989) Cell , vol.57 , pp. 201-209
    • Cotsarelis, G.1    Cheng, S.Z.2    Dong, G.3    Sun, T.T.4    Lavker, R.M.5
  • 6
    • 0031577291 scopus 로고    scopus 로고
    • Towards a molecular definition of keratinocyte activation after acute injury to stratified epithelia
    • Coulombe, P.A. 1997. Towards a molecular definition of keratinocyte activation after acute injury to stratified epithelia. Biochem. Biophys. Res. Commun. 236:231-238.
    • (1997) Biochem. Biophys. Res. Commun. , vol.236 , pp. 231-238
    • Coulombe, P.A.1
  • 7
    • 0001790971 scopus 로고
    • Molecular mechanisms of keratin gene disorders and other bullous diseases of the skin
    • S. Citi, editor. R.G. Landes Co., Austin, TX.
    • Coulombe, P.A., and E. Fuchs. 1994. Molecular mechanisms of keratin gene disorders and other bullous diseases of the skin. In Molecular Mechanisms in Epithelial Cell Junctions: From Development to Disease. S. Citi, editor. R.G. Landes Co., Austin, TX. 259-285.
    • (1994) Molecular Mechanisms in Epithelial Cell Junctions: From Development to Disease , pp. 259-285
    • Coulombe, P.A.1    Fuchs, E.2
  • 8
    • 0029365111 scopus 로고
    • Overexpression of human keratin 16 produces a distinct phenotype in transgenic mouse skin
    • Coulombe, P.A., N.S. Bravo, R.D. Paladini, D. Nguyen, and K. Takahashi. 1995. Overexpression of human keratin 16 produces a distinct phenotype in transgenic mouse skin. Biochem. Cell Biol. 73:611-618.
    • (1995) Biochem. Cell Biol. , vol.73 , pp. 611-618
    • Coulombe, P.A.1    Bravo, N.S.2    Paladini, R.D.3    Nguyen, D.4    Takahashi, K.5
  • 9
    • 0026329610 scopus 로고
    • A function for keratins and a common thread among different types of epidermolysis bullosa simplex diseases
    • Coulombe, P.A., M.E. Hutton, R. Vassar, and E. Fuchs. 1991. A function for keratins and a common thread among different types of epidermolysis bullosa simplex diseases. J. Cell Biol. 115:1661-1674.
    • (1991) J. Cell Biol. , vol.115 , pp. 1661-1674
    • Coulombe, P.A.1    Hutton, M.E.2    Vassar, R.3    Fuchs, E.4
  • 10
    • 0032432844 scopus 로고    scopus 로고
    • Molecular phylogeny of metazoan intermediate filament proteins
    • Erber, A., D. Riemer, M. Bovenschulte, and K. Weber. 1998. Molecular phylogeny of metazoan intermediate filament proteins. J. Mol. Evol. 47: 751-762.
    • (1998) J. Mol. Evol. , vol.47 , pp. 751-762
    • Erber, A.1    Riemer, D.2    Bovenschulte, M.3    Weber, K.4
  • 11
    • 0028568134 scopus 로고
    • Arrangement of a cluster of three mouse type I keratin genes expressed sequentially during esophageal-type epithelial cell differentiation
    • Filion, M., V. Sarafian, M. Lussier, C. Belanger, L. LaPointe, and A. Royal. 1994. Arrangement of a cluster of three mouse type I keratin genes expressed sequentially during esophageal-type epithelial cell differentiation. Genomics. 24:303-310.
    • (1994) Genomics , vol.24 , pp. 303-310
    • Filion, M.1    Sarafian, V.2    Lussier, M.3    Belanger, C.4    LaPointe, L.5    Royal, A.6
  • 12
    • 0018866880 scopus 로고
    • Changes in keratin gene expression during terminal differentiation of the keratinocyte
    • Fuchs, E., and H. Green. 1980. Changes in keratin gene expression during terminal differentiation of the keratinocyte. Cell. 19:1033-1042.
    • (1980) Cell , vol.19 , pp. 1033-1042
    • Fuchs, E.1    Green, H.2
  • 13
    • 0026725118 scopus 로고
    • Trans-genic mice expressing a mutant keratin 10 gene reveal the likely genetic basis for epidermolytic hyperkeratosis
    • Fuchs, E., R.A. Esteves, and P.A. Coulombe. 1992. Trans-genic mice expressing a mutant keratin 10 gene reveal the likely genetic basis for epidermolytic hyperkeratosis. Proc. Natl. Acad. Sci. USA. 89:6906-6010.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 6906-16010
    • Fuchs, E.1    Esteves, R.A.2    Coulombe, P.A.3
  • 14
    • 0026601915 scopus 로고
    • Wound repair, keratinocyte activation and integrin modulation
    • Grinnell, F. 1992. Wound repair, keratinocyte activation and integrin modulation. J. Cell Sci. 101:1-5.
    • (1992) J. Cell Sci. , vol.101 , pp. 1-5
    • Grinnell, F.1
  • 15
  • 16
    • 0032547734 scopus 로고    scopus 로고
    • Functional differences between keratins of stratified and simple epithelial
    • Hutton, E., R.D. Paladini, Q.C. Yu, M. Yen, P.A. Coulombe, and E. Fuchs. 1998. Functional differences between keratins of stratified and simple epithelial. Cell Biol. 143:1-13.
    • (1998) Cell Biol. , vol.143 , pp. 1-13
    • Hutton, E.1    Paladini, R.D.2    Yu, Q.C.3    Yen, M.4    Coulombe, P.A.5    Fuchs, E.6
  • 18
    • 0023134938 scopus 로고
    • Three cDNA sequences of mouse type I keratins. Cellular localization of the mRNAs in normal and hyperproliferative tissues
    • Knapp, B., M. Rentrop, J. Schweizer, and H. Winter. 1987. Three cDNA sequences of mouse type I keratins. Cellular localization of the mRNAs in normal and hyperproliferative tissues. J. Biol. Chem. 262:938-945.
    • (1987) J. Biol. Chem. , vol.262 , pp. 938-945
    • Knapp, B.1    Rentrop, M.2    Schweizer, J.3    Winter, H.4
  • 19
    • 0029865563 scopus 로고    scopus 로고
    • The molecular basis for inherited bullous diseases
    • Korge, B.P., and T. Krieg. 1996. The molecular basis for inherited bullous diseases. J. Mol. Med. 74:59-70.
    • (1996) J. Mol. Med. , vol.74 , pp. 59-70
    • Korge, B.P.1    Krieg, T.2
  • 20
    • 0027953771 scopus 로고
    • Hox genes in vertebrate development
    • Krumlauf, R. 1994. Hox genes in vertebrate development. Cell. 7:191-201.
    • (1994) Cell , vol.7 , pp. 191-201
    • Krumlauf, R.1
  • 21
    • 0032576580 scopus 로고    scopus 로고
    • Mutation of a major keratin phosphorylation site predisposes to hepatotoxic injury in transgenic mice
    • Ku, N.-O., S.A. Michie, R.M. Soetikno, E.Z. Resurreccion, R.L. Broome, and M.B. Omary. 1998. Mutation of a major keratin phosphorylation site predisposes to hepatotoxic injury in transgenic mice. J. Cell Biol. 143: 2023-2032.
    • (1998) J. Cell Biol. , vol.143 , pp. 2023-2032
    • Ku, N.-O.1    Michie, S.A.2    Soetikno, R.M.3    Resurreccion, E.Z.4    Broome, R.L.5    Omary, M.B.6
  • 22
    • 0023929591 scopus 로고
    • Cloning of the human keratin 18 gene and its expression in nonepithelial mouse cells
    • Kulesh, D.A., and R.G. Oshima. 1988. Cloning of the human keratin 18 gene and its expression in nonepithelial mouse cells. Mol. Cell Biol. 8:1540-1550.
    • (1988) Mol. Cell Biol. , vol.8 , pp. 1540-1550
    • Kulesh, D.A.1    Oshima, R.G.2
  • 23
    • 0028793640 scopus 로고
    • Keratins (K16 and K17) as markers of keratinocyte hyperproliferation in psoriasis in vivo and in vitro
    • Leigh, I.M., H. Navsaria, P.E. Purkis, I.A. McKay, P.E. Bowden, and P.N. Riddle. 1995. Keratins (K16 and K17) as markers of keratinocyte hyperproliferation in psoriasis in vivo and in vitro. Br. J. Dermatol. 133:501-511.
    • (1995) Br. J. Dermatol. , vol.133 , pp. 501-511
    • Leigh, I.M.1    Navsaria, H.2    Purkis, P.E.3    McKay, I.A.4    Bowden, P.E.5    Riddle, P.N.6
  • 24
    • 0024455099 scopus 로고
    • Isolation, sequence, and expression of a human keratin K5 gene: Transcriptional regulation of keratins and insights into pairwise control
    • Lersch, R., V. Stellmach, C. Stocks, G. Giudice, and E. Fuchs. 1989. Isolation, sequence, and expression of a human keratin K5 gene: transcriptional regulation of keratins and insights into pairwise control. Mol. Cell Biol. 9:3685-3697.
    • (1989) Mol. Cell Biol. , vol.9 , pp. 3685-3697
    • Lersch, R.1    Stellmach, V.2    Stocks, C.3    Giudice, G.4    Fuchs, E.5
  • 25
    • 0029043889 scopus 로고
    • The basal keratin network of stratified squamous epithelia: Defining K15 function in the absence of K14
    • Lloyd, C., Q.C. Yu, J. Cheng, K. Turksen, L. Degenstein, E. Hutton, and E. Fuchs. 1995. The basal keratin network of stratified squamous epithelia: Defining K15 function in the absence of K14. J. Cell Biol. 129:1329-1344.
    • (1995) J. Cell Biol. , vol.129 , pp. 1329-1344
    • Lloyd, C.1    Yu, Q.C.2    Cheng, J.3    Turksen, K.4    Degenstein, L.5    Hutton, E.6    Fuchs, E.7
  • 26
    • 0028814456 scopus 로고
    • Empigen BB: A useful detergent for solubilization and biochemical analysis of keratins
    • Lowthert, L.A., N.O. Ku, J. Liao, P.A. Coulombe, and B. Omary. 1995. Empigen BB: a useful detergent for solubilization and biochemical analysis of keratins. Biochem. Biophys. Res. Commun. 206:370-379.
    • (1995) Biochem. Biophys. Res. Commun. , vol.206 , pp. 370-379
    • Lowthert, L.A.1    Ku, N.O.2    Liao, J.3    Coulombe, P.A.4    Omary, B.5
  • 27
    • 2642684550 scopus 로고    scopus 로고
    • Lessons from keratin 18 knock-out mice: Formation of novel keratin filaments, secondary loss of keratin 7 and accumulation of liver-specific keratin 8-positive aggregates
    • Magin, T.M., R. Schroder, S. Leitgeb, F. Wanninger, K. Zatloukal, C. Grund, and D.W. Melton. 1998. Lessons from keratin 18 knock-out mice: formation of novel keratin filaments, secondary loss of keratin 7 and accumulation of liver-specific keratin 8-positive aggregates. J. Cell Biol. 140:1441-1451.
    • (1998) J. Cell Biol. , vol.140 , pp. 1441-1451
    • Magin, T.M.1    Schroder, R.2    Leitgeb, S.3    Wanninger, F.4    Zatloukal, K.5    Grund, C.6    Melton, D.W.7
  • 28
    • 0023181424 scopus 로고
    • Changes in keratinocyte maturation during wound healing
    • Mansbridge, J.N., and A.M. Knapp. 1987. Changes in keratinocyte maturation during wound healing. J. Invest. Dermatol. 89:253-263.
    • (1987) J. Invest. Dermatol. , vol.89 , pp. 253-263
    • Mansbridge, J.N.1    Knapp, A.M.2
  • 29
    • 0032547830 scopus 로고    scopus 로고
    • Onset of keratin 17 expression coincides with the definition of major epithelial lineages during mouse skin development
    • McGowan, K., and P.A. Coulombe. 1998. Onset of keratin 17 expression coincides with the definition of major epithelial lineages during mouse skin development. J. Cell Biol. 143:14-31.
    • (1998) J. Cell Biol. , vol.143 , pp. 14-31
    • McGowan, K.1    Coulombe, P.A.2
  • 30
    • 0032234101 scopus 로고    scopus 로고
    • The wound repair-associated keratins K6, K16 and K17: Insights into the role of intermediate filaments in specifying keratinocyte cytoarchitecture
    • J.R. Harris and H. Herrmann, editors. Plenum Publishing Co., London
    • McGowan, K., and P.A. Coulombe. 1998. The wound repair-associated keratins K6, K16 and K17: Insights into the role of intermediate filaments in specifying keratinocyte cytoarchitecture. In Subcellular Biochemistry: Intermediate Filaments. Vol. 31. J.R. Harris and H. Herrmann, editors. Plenum Publishing Co., London. 173-203.
    • (1998) Subcellular Biochemistry: Intermediate Filaments , vol.31 , pp. 173-203
    • McGowan, K.1    Coulombe, P.A.2
  • 33
    • 0029970965 scopus 로고    scopus 로고
    • Keratin 19 as a biochemical marker of skin stem cells in vivo and in vitro: Keratin 19 expressing cells are differentially localized in function of anatomic sites, and their number varies with donor age and culture stage
    • Michel, M., N. Torok, M.J. Godhout, M. Lussier, P. Gaudreau, A. Royal, and L. Germain. 1996. Keratin 19 as a biochemical marker of skin stem cells in vivo and in vitro: keratin 19 expressing cells are differentially localized in function of anatomic sites, and their number varies with donor age and culture stage. J. Cell Sci. 109:1017-1028.
    • (1996) J. Cell Sci. , vol.109 , pp. 1017-1028
    • Michel, M.1    Torok, N.2    Godhout, M.J.3    Lussier, M.4    Gaudreau, P.5    Royal, A.6    Germain, L.7
  • 34
    • 0030028120 scopus 로고    scopus 로고
    • Close linkage of the two keratin gene clusters in the human genome
    • Milisavljevic, V., I.M. Freedberg, and M. Blumenberg. 1996. Close linkage of the two keratin gene clusters in the human genome. Genomics. 34:134-138.
    • (1996) Genomics. , vol.34 , pp. 134-138
    • Milisavljevic, V.1    Freedberg, I.M.2    Blumenberg, M.3
  • 35
    • 0020467073 scopus 로고
    • The catalog of human cytokeratins: Patterns of expression in normal epithelia, tumors and cultured cells
    • Moll, R., W.W. Franke, D.L. Schiller, B. Geiger, and R. Krepler. 1982. The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells. Cell. 31:11-24.
    • (1982) Cell , vol.31 , pp. 11-24
    • Moll, R.1    Franke, W.W.2    Schiller, D.L.3    Geiger, B.4    Krepler, R.5
  • 36
    • 0020587062 scopus 로고
    • The 50- and 58-kd keratin classes as molecular markers for stratified squamous epithelia: Cell culture studies
    • Nelson, W.G., and T.T. Sun. 1983. The 50- and 58-kd keratin classes as molecular markers for stratified squamous epithelia: cell culture studies. J. Cell Biol. 97:244-251.
    • (1983) J. Cell Biol. , vol.97 , pp. 244-251
    • Nelson, W.G.1    Sun, T.T.2
  • 38
    • 0002963790 scopus 로고
    • Differentiation-specific expression of keratin pairs
    • R.D. Goldman and P.M. Steinert, editors. Plenum Publishing Corp., New York.
    • O'Guin, W.M., A. Schermer, M. Lynch, and T.-T. Sun. 1990. Differentiation-specific expression of keratin pairs. In Cellular and Molecular Biology of Intermediate Filaments. R.D. Goldman and P.M. Steinert, editors. Plenum Publishing Corp., New York. 301-334.
    • (1990) Cellular and Molecular Biology of Intermediate Filaments , pp. 301-334
    • O'Guin, W.M.1    Schermer, A.2    Lynch, M.3    Sun, T.-T.4
  • 39
    • 0032563572 scopus 로고    scopus 로고
    • Directed expression of keratin 16 to the progenitor basal cells of transgenic mouse skin delays skin maturation
    • Paladini, R.D., and P.A. Coulombe. 1998. Directed expression of keratin 16 to the progenitor basal cells of transgenic mouse skin delays skin maturation. J. Cell Biol. 142:1035-1051.
    • (1998) J. Cell Biol. , vol.142 , pp. 1035-1051
    • Paladini, R.D.1    Coulombe, P.A.2
  • 40
    • 0030035021 scopus 로고    scopus 로고
    • Onset of reepithelialization after skin injury correlates with a reorganization of keratin filaments in wound edge keratinocytes: Defining a potential role for keratin 16
    • Paladini, R.D., K. Takahashi, N.S. Bravo, and P.A. Coulombe. 1996. Onset of reepithelialization after skin injury correlates with a reorganization of keratin filaments in wound edge keratinocytes: defining a potential role for keratin 16. J. Cell Biol. 132:381-397.
    • (1996) J. Cell Biol. , vol.132 , pp. 381-397
    • Paladini, R.D.1    Takahashi, K.2    Bravo, N.S.3    Coulombe, P.A.4
  • 42
    • 0029670060 scopus 로고    scopus 로고
    • Gene targeting at the mouse keratin 10 locus: Severe skin fragility and changes in cytokeratin expression in the epidermis
    • Porter, R.M., S. Leitgeb, D.M. Melton, O. Swensson, R.A.J. Eady, and T.M. Magin. 1996. Gene targeting at the mouse keratin 10 locus: severe skin fragility and changes in cytokeratin expression in the epidermis. J. Cell Biol. 132:925-936.
    • (1996) J. Cell Biol. , vol.132 , pp. 925-936
    • Porter, R.M.1    Leitgeb, S.2    Melton, D.M.3    Swensson, O.4    Eady, R.A.J.5    Magin, T.M.6
  • 43
    • 0033610836 scopus 로고    scopus 로고
    • CDNA cloning, expression, and assembly characteristics of mouse keratin 16
    • Porter, R.M., A.M. Hutcheson, E.L. Rugg, R.A. Quinlan, and E.B. Lane. 1998. cDNA cloning, expression, and assembly characteristics of mouse keratin 16. J. Biol. Chem. 273:32265-32272.
    • (1998) J. Biol. Chem. , vol.273 , pp. 32265-32272
    • Porter, R.M.1    Hutcheson, A.M.2    Rugg, E.L.3    Quinlan, R.A.4    Lane, E.B.5
  • 45
    • 0028844205 scopus 로고
    • Keratin 13 point mutation underlies the hereditary mucosal epithelial disorder white sponge nevus
    • Richard, G., L.V. De, B. Didona, S.J. Bale, and J.G. Compton. 1995. Keratin 13 point mutation underlies the hereditary mucosal epithelial disorder white sponge nevus. Nat. Genet. 11:453-455.
    • (1995) Nat. Genet. , vol.11 , pp. 453-455
    • Richard, G.1    De, L.V.2    Didona, B.3    Bale, S.J.4    Compton, J.G.5
  • 46
    • 0000352812 scopus 로고
    • Electron microscopy of wool
    • Rogers, G.E. 1959. Electron microscopy of wool. J. Ultrastruct. Res. 2:309-330.
    • (1959) J. Ultrastruct. Res. , vol.2 , pp. 309-330
    • Rogers, G.E.1
  • 48
    • 0026767679 scopus 로고
    • Optimization of murine keratinocyte culture for the production of graftable epidermal sheets
    • Rouabhia, M., L. Germain, F. Belanger, R. Guignard, and F.A. Auger. 1992. Optimization of murine keratinocyte culture for the production of graftable epidermal sheets. J. Dermatol. 19:325-334.
    • (1992) J. Dermatol. , vol.19 , pp. 325-334
    • Rouabhia, M.1    Germain, L.2    Belanger, F.3    Guignard, R.4    Auger, F.A.5
  • 51
    • 0028941493 scopus 로고
    • Inhibition of skin development by targeted expression of a dominant-negative retinoic acid receptor
    • Saitou, M., S. Sugai, T. Tanaka, K. Shimouchi, E. Fuchs, S. Narumiya, and A. Kakizuka. 1995. Inhibition of skin development by targeted expression of a dominant-negative retinoic acid receptor. Nature. 374:159-162.
    • (1995) Nature , vol.374 , pp. 159-162
    • Saitou, M.1    Sugai, S.2    Tanaka, T.3    Shimouchi, K.4    Fuchs, E.5    Narumiya, S.6    Kakizuka, A.7
  • 55
    • 0023683885 scopus 로고
    • Use of monospecific antisera and cRNA probes to localize the major changes in keratin expression during normal and abnormal epidermal differentiation
    • Stoler, A., R. Kopan, M. Duvic, and E. Fuchs. 1988. Use of monospecific antisera and cRNA probes to localize the major changes in keratin expression during normal and abnormal epidermal differentiation. J. Cell Biol. 107:427-446.
    • (1988) J. Cell Biol. , vol.107 , pp. 427-446
    • Stoler, A.1    Kopan, R.2    Duvic, M.3    Fuchs, E.4
  • 56
    • 0029905020 scopus 로고    scopus 로고
    • A transgenic mouse model with an inducible skin blistering disease phenotype
    • Takahashi, K., and P.A. Coulombe. 1996. A transgenic mouse model with an inducible skin blistering disease phenotype. Proc. Natl. Acad. Sci. USA. 93:14776-14781.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 14776-14781
    • Takahashi, K.1    Coulombe, P.A.2
  • 57
    • 0030922590 scopus 로고    scopus 로고
    • Defining a region of the human keratin 6a gene that confers inducible expression in stratified epithelia of transgenic mice
    • Takahashi, K., and P.A. Coulombe. 1997. Defining a region of the human keratin 6a gene that confers inducible expression in stratified epithelia of transgenic mice. J. Biol. Chem. 272:11979-11985.
    • (1997) J. Biol. Chem. , vol.272 , pp. 11979-11985
    • Takahashi, K.1    Coulombe, P.A.2
  • 58
    • 0028109866 scopus 로고
    • Increased expression of keratin 16 causes anomalies in cytoarchitecture and keratinization in transgenic mouse skin
    • Takahashi, K., J. Folmer, and P.A. Coulombe. 1994. Increased expression of keratin 16 causes anomalies in cytoarchitecture and keratinization in transgenic mouse skin. J. Cell Biol. 127:505-520.
    • (1994) J. Cell Biol. , vol.127 , pp. 505-520
    • Takahashi, K.1    Folmer, J.2    Coulombe, P.A.3
  • 59
    • 0032532129 scopus 로고    scopus 로고
    • The two functional type II keratin 6 genes of mouse show a differential regulation and evolved independently from their human orthologs
    • Takahashi, K., B. Yan, K. Yamanishi, S. Imamura, and P.S. Coulombe. 1998. The two functional type II keratin 6 genes of mouse show a differential regulation and evolved independently from their human orthologs. Genomics. 53:170-183.
    • (1998) Genomics. , vol.53 , pp. 170-183
    • Takahashi, K.1    Yan, B.2    Yamanishi, K.3    Imamura, S.4    Coulombe, P.S.5
  • 60
    • 0026442553 scopus 로고
    • Characterization of the human gene encoding cytokeratin 17 and its expression pattern
    • Troyanovsky, S.M., R.E. Leube, and W.W. Franke. 1992. Characterization of the human gene encoding cytokeratin 17 and its expression pattern. Eur. J. Cell Biol. 59:127-137.
    • (1992) Eur. J. Cell Biol. , vol.59 , pp. 127-137
    • Troyanovsky, S.M.1    Leube, R.E.2    Franke, W.W.3
  • 61
    • 0023037150 scopus 로고
    • Evidence for posttranscriptional regulation of the keratins expressed during hyperproliferation and malignant transformation in human epidermis
    • Tyner, A.L., and E. Fuchs. 1986. Evidence for posttranscriptional regulation of the keratins expressed during hyperproliferation and malignant transformation in human epidermis. J. Cell Biol. 103:1945-1955.
    • (1986) J. Cell Biol. , vol.103 , pp. 1945-1955
    • Tyner, A.L.1    Fuchs, E.2
  • 62
    • 0000425845 scopus 로고
    • Tissue-specific and differentiation-specific expression of a human K14 keratin gene in transgenic mice
    • Vassar, R., M. Rosenberg, S. Ross, A. Tyner, and E. Fuchs. 1989. Tissue-specific and differentiation-specific expression of a human K14 keratin gene in transgenic mice. Proc. Natl. Acad. Sci. USA. 86:1563-1567.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 1563-1567
    • Vassar, R.1    Rosenberg, M.2    Ross, S.3    Tyner, A.4    Fuchs, E.5
  • 63
    • 0025976155 scopus 로고
    • Mutant keratin expression in transgenic mice causes marked abnormalities resembling a human genetic skin disease
    • Vassar, R., P.A. Coulombe, L. Degenstein, K. Albers, and E. Fuchs. 1991. Mutant keratin expression in transgenic mice causes marked abnormalities resembling a human genetic skin disease. Cell. 64:365-380.
    • (1991) Cell , vol.64 , pp. 365-380
    • Vassar, R.1    Coulombe, P.A.2    Degenstein, L.3    Albers, K.4    Fuchs, E.5
  • 65
    • 0031452569 scopus 로고    scopus 로고
    • A proline residue in the a-helical rod domain of type I keratin 16 destabilizes keratin heterotetramers and influences incorporation into filaments
    • Wawersik, M., R.D. Paladini, E. Noensie, and P.A. Coulombe. 1997. A proline residue in the a-helical rod domain of type I keratin 16 destabilizes keratin heterotetramers and influences incorporation into filaments. J. Biol. Chem. 272:32557-32565.
    • (1997) J. Biol. Chem. , vol.272 , pp. 32557-32565
    • Wawersik, M.1    Paladini, R.D.2    Noensie, E.3    Coulombe, P.A.4
  • 66
    • 0021223740 scopus 로고
    • Monoclonal antibody analysis of keratin expression in epidermal diseases: A 48- and 56-kdalton keratin as molecular markers for hyperproliferative keratinocytes
    • Weiss, R.A., R. Eichner, and T.T. Sun. 1984. Monoclonal antibody analysis of keratin expression in epidermal diseases: a 48- and 56-kdalton keratin as molecular markers for hyperproliferative keratinocytes. J. Cell Biol. 98:1397-1406.
    • (1984) J. Cell Biol. , vol.98 , pp. 1397-1406
    • Weiss, R.A.1    Eichner, R.2    Sun, T.T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.