Simple epithelium keratins are required for maintenance of hepatocyte integrity

American Journal of Pathology

Volumn 151, Issue 6, 1997, Pages 1673-1683

  Loranger, Anne ^a   Duclos, Sophie ^a   Grenier, Andrée ^a   Price, Jennifer ^b   Wilson Heiner, Marcia ^c   Baribault, Hélène ^c   Marceau, Normand ^a  

^a LAVAL UNIVERSITY   (Canada)

^b SCRIPPS CLINIC   (United States)

^c BURNHAM INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PENTOBARBITAL;

ARTICLE; CELL MEMBRANE; COLORECTAL DISEASE; DISEASE SEVERITY; EPITHELIUM; FATTY LIVER; HUMAN; HUMAN CELL; INFLAMMATION; LIVER CELL; LIVER RESECTION; PHENOTYPE; PORTAL VEIN BLOOD FLOW; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; TRANSGENIC ANIMAL;

EID: 0030699530     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. Moll R, Franke WW, Schiller DL, Geiger B, Krepler R: The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells. Cell 1982, 31:11-24
2. Fuchs E, Weber K: Intermediate filaments: structure, dynamics, function and disease. Annu Rev Biochem 1994, 63:345-382
3. Oshima RG: Intermediate filament molecular biology. Curr Opin Cell Biol 1992, 4:110-116
4. McLean WHI, Lane EB: Intermediate filaments in disease. Curr Opin Cell Biol 1995, 7:118-125
5. Steinert PM: Structure, function, and dynamics of keratin intermediate filaments. J Invest Dermatol 1993, 100:729-734
6. Coulombe PA, Fuchs E: Molecular mechanisms of keratin gene disorders and other bullous diseases of the skin. Molecular Mechanisms in Epithelial Cell Junctions: From Development to Disease. Edited by S Citi. Austin, RG Landes Co, 1994, pp 259-285
7. Alberts KM, Davis FE, Perrone TN, Lee EY, Liu Y, Vore M: Expression of an epidermal keratin protein in liver of transgenic mice causes structural and functional abnormalities. J Cell Biol 1995, 128:157-169
8. Ku NO, Michie S, Oshima RG, Omary MB: Chronic hepatitis, hepatocyte fragility, and increased soluble phosphoglycokeratins in transgenic mice expressing a keratin 18 conserved arginine mutant. J Cell Biol 1995, 131:1303-1314
9. Marceau N, Loranger A: Cytokeratin expression, fibrillar organization, and subtle function in liver cells. Biochem Cell Biol 1995, 73:619-625
10. Oshima RG, Baribault H, Caulin C: Oncogenic regulation and function of keratins 8 and 18. Cancer Metastasis Rev 1996, 15:445-471
11. Marceau N: Epithelial cell lineages in developing, restoring, and transforming liver: evidence for the existence of a "differentiation window". Gut 1994, 35:294-296
12. Shiojiri N, Lemire JM, Fausto N: Cell lineages and oval cell progenitors in rat liver development. Cancer Res 1991, 51:2611-2620
13. Van Eyken P, Desmet VJ: Development of intrahepatic bile ducts, ductular metaplasia of hepatocytes, and cytokeratin patterns in various types of human hepatic neoplasms. The Role of Cell Types in Hepatocarcinogenesis. Edited by AE Sirica. Boca Raton, CRC Press Inc, 1992, pp 227-264
14. Michel M, Török N, Godbout MJ, Lussier M, Gaudreau P, Royal A, Germain L: Keratin 19 as a biochemical marker of skin stem cells in vivo, and in vitro: keratin 19 expressing cells are differentially localized in function of anatomic sites, and their number varies with donor age, and culture stage. J Cell Sci 1996, 109:1017-1028
15. Rossant J, Joyner AL: Towards a molecular-genetic analysis of mammalian development. Trends Genet 1989, 5:277-283
16. Baribault H, Price J, Miyai K, Oshima RG: Mid-gestational lethality in mice lacking keratin 8. Genes Dev 1992, 7:1991-2002
17. Baribault H, Penner J, lozzo RV, Wilson-Heiner M: Colorectal hyperplasia and inflammation in keratin 8-deficient FVB/N mice. Genes Dev 1994, 8:2964-2973
18. Vasseur M, Duprey P, Brulet P, Jacob F: One gene and one pseudogene for the cytokeratin endo A. Proc Natl Acad Sci USA 1985, 82:1155-1159
19. Shull MM, Ormsby I, Kier AB, Pawlowski S, Diebold RJ, Yin M, Allen R, Sidman C, Proetzel G, Calvin D: Targeted disruption of the mouse transforming growth factor-β 1 gene results in multifocal inflammatory disease. Nature 1992, 359:693-9
20. Loranger A, Barrault C, Youseff I, Tuchweber B: Structural and functional alterations of hepatocytes during transient phalloidin-induced cholestasis in the rat. Toxicol Appl Pharmacol 1996, 137:100-111
21. Loranger A, Tuchweber B, Youseff I, Marceau N: Biliary secretion and actin-cytokeratin filament distribution in rat hepatocytes during phalloidin-induced cholestasis. Biochem Cell Biol 1995, 73:641-649
22. Higgins GM, Anderson RM: Experimental pathology of the liver: I. restoration of the liver of the white rat following partial surgical removal. Arch Path 1931, 12:186-202
23. Seglen PO: Preparation of isolated rat liver cells. Methods in Cell Biology. Edited by D Prescott. New York, Academic Press, 1976, pp 29-83
24. Deschênes J, Valet JP, Marceau N: Hepatocytes from newborn and weanling rats in monolayer culture: isolation by perfusion fibronectin-mediated adhesion, spreading, and functional activities. In Vitro 1980, 16:722-730
25. Blouin R, Blouin MJ, Royal I, Grenier A, Roop DR, Loranger A, Marceau N: Cytokeratin 14 expression in rat liver cells in culture, and localization in vivo. Differentiation 1992, 52:45-54
26. Mc Dowell EM, Trump BF: Histologic fixatives suitable for diagnosis light and electron microscopy. Arch Pathol Lab Med 1976, 100:405-414
27. Brixova E, Dzurikova V: Determination of glycogen, lipids and proteins in hepatic needle biopsy. Clin Chim Acta 1972, 36:543-548
28. Uchiyama M, Mihara M: Determination of malonaldehyde precursor in tissues by thiobarbituric acid test. Anal Biochem 1978, 86:271-278
29. Laemmli UK: Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970, 227:680-685
30. Royal I, Gourdeau H, Blouin R, Marceau N: Down-regulation of cytokeratin 14 mRNA in polyoma virus middle T-transformed rat liver epithelial cells. Cell Growth Differ 1992, 3:589-596
31. Towbin H, Stochelen T, Gorden H: Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci USA 1979, 76:1350-1354
32. Royal I, Raptis L, Druker BJ, Marceau N: Down-regulation of cytokeratin 14 gene expression by the polyoma virus middle T antigen is dependent on c-src association but independent of full transformation in rat liver nonparenchymal epithelial cells. Cell Growth Differ 1996, 7:737-743
33. Bosser BG, Gores GJ: Liver cell necrosis: cellular mechanisms and clinical implications. Gastroenterology 1995, 108:252-275
34. Kawahara H, French SW: Role of cytoskeleton in canalicular contraction in cultured differentiated hepatocytes. Am J Pathol 1990, 136: 521-532
35. Tsukada N, Ackerley CA, Phillips MJ: The structure and organization of the bile canalicular cytoskeleton with special reference to actin and actin-binding proteins. Hepatology 1995, 21:1106-1113
36. Fausto N, Webber EM: Mechanismes of growth regulation in liver regeneration and hepatic carcinogenesis. Prog Liver Dis 1993, 11: 115-137
37. Mitchell P: Keilin's respiratory chain concept and its chemosmotic consequences. Science 1979, 206:1148-1159
38. King H, Hawtof DB: Accidental intra-arterial injection of ether. JAMA 1963, 184:241-242
39. Loranger A, Tuchweber B, Gicquaud C, St-Pierre S, Côté MG: Toxicity of peptides of Amanita virosa mushrooms in mice. Fundam Appl Toxicol 1985, 5:114-1152
40. Arias IM, Che M, Gatmaitan Z, Leveille C, Nishida T, St. Pierre M: The Biology of the Bile Canaliculus. Hepatology 1993, 17:318-329
41. Brown SES, Quattrochi LC, Guzelian PS: Characterization of a pretranscriptional pathway for induction by phenobarbital of cytochrome P450 3A23 in primary cultures of adult rat hepatocytes. Arch Biochem Biophys 1997, 342:137-142
42. Ku NO, Weight TL, Terrault NA, Gish R, Omary MB: Mutation of human keratin 18 in association with cryptogenic cirrhosis. J Clin Invest 1997, 99:19-23
43. Greeve ML, Ferrell MK, Combs C, Roberts J, Ascher N, Wright TL: Cirrhosis of undefined pathogenesis: absence of evidence for unknown viruses or autoimmune processes. Hepatology 1993, 17:593-598
44. Omary MB, Ku NO: Intermediate filament proteins of the liver: emerging disease association and functions. Hepatology 1997, 25:1043-1048