메뉴 건너뛰기




Volumn 61, Issue 2, 1996, Pages 129-139

A transgenic mouse model that recapitulates the clinical features of both neonatal and adult forms of the skin disease epidermolytic hyperkeratosis

Author keywords

[No Author keywords available]

Indexed keywords

KERATIN; KERATOHYALIN; STRUCTURAL PROTEIN;

EID: 0029750269     PISSN: 03014681     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002580050177     Document Type: Article
Times cited : (44)

References (63)
  • 1
    • 0025076790 scopus 로고
    • A single human keratin 18 gene is expressed in diverse epithelial cells of transgenic mice
    • Abe M, Oshima RG (1990) A single human keratin 18 gene is expressed in diverse epithelial cells of transgenic mice. J Cell Biol 111:1197-1206
    • (1990) J Cell Biol , vol.111 , pp. 1197-1206
    • Abe, M.1    Oshima, R.G.2
  • 2
    • 0023545331 scopus 로고
    • The expression of mutant keratin cDNAs transfected in simple epithelia and squamous cell carcinoma lines
    • Albers K, Fuchs F (1987) The expression of mutant keratin cDNAs transfected in simple epithelia and squamous cell carcinoma lines. J Cell Biol 105:791-806
    • (1987) J Cell Biol , vol.105 , pp. 791-806
    • Albers, K.1    Fuchs, F.2
  • 3
    • 0024504168 scopus 로고
    • Expression of mutant keratin cDNAs in epithelial cells reveals possible mechanismas for initiation and assembly of intermediate filaments
    • Albers K, Fuchs F (1989) Expression of mutant keratin cDNAs in epithelial cells reveals possible mechanismas for initiation and assembly of intermediate filaments. J Cell Biol 108:1477-1493
    • (1989) J Cell Biol , vol.108 , pp. 1477-1493
    • Albers, K.1    Fuchs, F.2
  • 4
    • 0020506402 scopus 로고
    • Genetically induced abnormalities of epidermal differentiation and ultrastructure in ichthyoses and epidermolyses: Pathogenesis, heterogeneity, fetal manifestation, and prenatal diagnosis
    • Anton-Lamprecht I (1983) Genetically induced abnormalities of epidermal differentiation and ultrastructure in ichthyoses and epidermolyses: pathogenesis, heterogeneity, fetal manifestation, and prenatal diagnosis. J Invest Dermatol [Suppl] 81:149s-156s
    • (1983) J Invest Dermatol [Suppl] , vol.81
    • Anton-Lamprecht, I.1
  • 6
    • 0025674247 scopus 로고
    • Cell type-specific and efficient synthesis of human cytokeratin 19 in transgenic mice
    • Bader BL, Franke WW (1990) Cell type-specific and efficient synthesis of human cytokeratin 19 in transgenic mice. Differentiation 45:109-118
    • (1990) Differentiation , vol.45 , pp. 109-118
    • Bader, B.L.1    Franke, W.W.2
  • 7
    • 0019497112 scopus 로고
    • Hereditary epidermolytic palmoplantar keratoderma
    • Blasik LG, Dimond RL, Baughmann RD (1981) Hereditary epidermolytic palmoplantar keratoderma. Arch Dermatol 117: 229-231
    • (1981) Arch Dermatol , vol.117 , pp. 229-231
    • Blasik, L.G.1    Dimond, R.L.2    Baughmann, R.D.3
  • 8
    • 0026345962 scopus 로고
    • Epidermolysis bullosa simplex: Evidence in two families for keratin gene abnormalities
    • Bonifas JM, Rothman AL, Epstein EH (1991) Epidermolysis bullosa simplex: evidence in two families for keratin gene abnormalities. Science 254:1202-1205
    • (1991) Science , vol.254 , pp. 1202-1205
    • Bonifas, J.M.1    Rothman, A.L.2    Epstein, E.H.3
  • 10
    • 0026437938 scopus 로고
    • Genetic manipulation of the mouse via gene targeting in embryonic stem cells
    • Bradley A, Ramierez-Solis R, Zheng H, Davis A (1992) Genetic manipulation of the mouse via gene targeting in embryonic stem cells. Ciba Found Symp 165:256-269
    • (1992) Ciba Found Symp , vol.165 , pp. 256-269
    • Bradley, A.1    Ramierez-Solis, R.2    Zheng, H.3    Davis, A.4
  • 11
    • 0027943989 scopus 로고
    • A human keratin 14 "knochout": The absence of K14 leads to severe epidermolysis bullosa simplex and a function for an intermediate filament protein
    • Chan Y-M, Anton-Lamprecht I, Yu Q-C, Jackel A, Zabel B, Ernst J-P, Fuchs E (1994) A human keratin 14 "knochout": the absence of K14 leads to severe epidermolysis bullosa simplex and a function for an intermediate filament protein. Genes Dev 8:2574-2587
    • (1994) Genes Dev , vol.8 , pp. 2574-2587
    • Chan, Y.-M.1    Anton-Lamprecht, I.2    Yu, Q.-C.3    Jackel, A.4    Zabel, B.5    Ernst, J.-P.6    Fuchs, E.7
  • 13
    • 0026666391 scopus 로고
    • Characterization of human cytokeratin 2, an epidermal cytoskeletal protein synthesized late during differentiation
    • Collin C, Moll R, Kubicka S, Ouhayoun JP, Franke WW (1992) Characterization of human cytokeratin 2, an epidermal cytoskeletal protein synthesized late during differentiation. Exp Cell Res 202:132-141
    • (1992) Exp Cell Res , vol.202 , pp. 132-141
    • Collin, C.1    Moll, R.2    Kubicka, S.3    Ouhayoun, J.P.4    Franke, W.W.5
  • 14
    • 0025861772 scopus 로고
    • Point mutations in human keratin 14 genes of epidermolysis bullosa simplex patients: Genetic and functional analysis
    • Coulombe PA, Hutton ME, Letai A, Herbert A, Paller A, Fuchs E (1991) Point mutations in human keratin 14 genes of epidermolysis bullosa simplex patients: genetic and functional analysis. Cell 66:1301-1311
    • (1991) Cell , vol.66 , pp. 1301-1311
    • Coulombe, P.A.1    Hutton, M.E.2    Letai, A.3    Herbert, A.4    Paller, A.5    Fuchs, E.6
  • 17
    • 0026555825 scopus 로고
    • Lipid and protein structures in the permeability barrier of mammalian epidermis
    • Downing DT (1992) Lipid and protein structures in the permeability barrier of mammalian epidermis. J Lipid Res 33:301-313
    • (1992) J Lipid Res , vol.33 , pp. 301-313
    • Downing, D.T.1
  • 18
    • 0024325324 scopus 로고
    • Structure, function and differentiation of the keratinocyte
    • Eckert RL (1989) Structure, function and differentiation of the keratinocyte. Physiol Rev 69:1316-1346
    • (1989) Physiol Rev , vol.69 , pp. 1316-1346
    • Eckert, R.L.1
  • 19
    • 0015849213 scopus 로고
    • Ichthyosiform dermatoses
    • Frost P (1973) Ichthyosiform dermatoses. J Invest Dermatol 60:541-552
    • (1973) J Invest Dermatol , vol.60 , pp. 541-552
    • Frost, P.1
  • 20
    • 0018866880 scopus 로고
    • Changes in keratin gene expression during terminal differentiation of the keratinocyte
    • Fuchs E, Green H (1980) Changes in keratin gene expression during terminal differentiation of the keratinocyte. Cell 19:1033-1042
    • (1980) Cell , vol.19 , pp. 1033-1042
    • Fuchs, E.1    Green, H.2
  • 21
    • 0026725118 scopus 로고
    • Transgenic mice expressing a mutant keratin 10 gene reveal the likely genetic basis for epidermolytic hyperkeratosis
    • Fuchs E, Esteves RA, Coulombe PA (1992) Transgenic mice expressing a mutant keratin 10 gene reveal the likely genetic basis for epidermolytic hyperkeratosis. Proc Natl Acad Sci USA 89:6909-6910
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 6909-6910
    • Fuchs, E.1    Esteves, R.A.2    Coulombe, P.A.3
  • 24
    • 0020692676 scopus 로고
    • Epidermolytie hyperkeratosis: Ultrastructure and biochemistry of skin and amniotic fluid cells from two affected fetuses and a newborn infant
    • Holbrook KA, Dale BA, Sybert VP, Sagbiel RW (1983) Epidermolytie hyperkeratosis: ultrastructure and biochemistry of skin and amniotic fluid cells from two affected fetuses and a newborn infant. J Invest Dermatol 80:222-227
    • (1983) J Invest Dermatol , vol.80 , pp. 222-227
    • Holbrook, K.A.1    Dale, B.A.2    Sybert, V.P.3    Sagbiel, R.W.4
  • 25
    • 0028314844 scopus 로고
    • Abnormal keratin 1 and 10 cytoskeleton in cultured keratinocytes from epidermolytic hyperkeratosis caused by keratin 10 mutations
    • Huber M, Scaletta C, Benathan M, Frenk E, Greenhalgh DA, Rothnagel JA, Roop DR, Hohl D (1994) Abnormal keratin 1 and 10 cytoskeleton in cultured keratinocytes from epidermolytic hyperkeratosis caused by keratin 10 mutations. J Invest Dermatol 102:691-694
    • (1994) J Invest Dermatol , vol.102 , pp. 691-694
    • Huber, M.1    Scaletta, C.2    Benathan, M.3    Frenk, E.4    Greenhalgh, D.A.5    Rothnagel, J.A.6    Roop, D.R.7    Hohl, D.8
  • 27
    • 0026636535 scopus 로고
    • Selective involvement of keratins K1 and K10 in the cytoskeletal abnormality of epidermolytic hyperkeratosis (bullous congenital ichthyosiform erythroderma)
    • Ishida-Yamamoto A, McGrath JA, Judge MR, Leigh IM, Lane EB, Eady RAJ (1992) Selective involvement of keratins K1 and K10 in the cytoskeletal abnormality of epidermolytic hyperkeratosis (bullous congenital ichthyosiform erythroderma). J Invest Dermatol 99:19-26
    • (1992) J Invest Dermatol , vol.99 , pp. 19-26
    • Ishida-Yamamoto, A.1    McGrath, J.A.2    Judge, M.R.3    Leigh, I.M.4    Lane, E.B.5    Eady, R.A.J.6
  • 30
    • 0001166951 scopus 로고
    • A formaldehyde-glutaraldehyde fixative of high osmolarity for use in electron microscopy
    • Karnovsky MJ (1965) A formaldehyde-glutaraldehyde fixative of high osmolarity for use in electron microscopy. J Cell Biol 27:137A-138A
    • (1965) J Cell Biol , vol.27
    • Karnovsky, M.J.1
  • 32
    • 0014749365 scopus 로고
    • Localized epidermolytic hyperkeratosis. A form of keratoma of the palms and soles
    • Klaus S, Weinstein GD, Frost P (1970) Localized epidermolytic hyperkeratosis. A form of keratoma of the palms and soles. Arch Dermatol 101:272-275
    • (1970) Arch Dermatol , vol.101 , pp. 272-275
    • Klaus, S.1    Weinstein, G.D.2    Frost, P.3
  • 33
    • 0022454679 scopus 로고
    • Cytokeratin no. 9, an epidermal type 1 keratin characteristic of a special program of keratinocyte differentiation displaying body site specificity
    • Knapp AC, Franke WW, Heid H, Hatzfeld M, Jorcano JL, Moll R (1986) Cytokeratin no. 9, an epidermal type 1 keratin characteristic of a special program of keratinocyte differentiation displaying body site specificity. J Cell Biol 103:657-667
    • (1986) J Cell Biol , vol.103 , pp. 657-667
    • Knapp, A.C.1    Franke, W.W.2    Heid, H.3    Hatzfeld, M.4    Jorcano, J.L.5    Moll, R.6
  • 34
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli UK (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 37
    • 0020467073 scopus 로고
    • The catalog of human cytokeratins: Patterns of expression in normal epithelia, tumors and cultured cells
    • Moll R, Franke WW, Schiller DL (1982) The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells. Cell 31:11-24
    • (1982) Cell , vol.31 , pp. 11-24
    • Moll, R.1    Franke, W.W.2    Schiller, D.L.3
  • 38
  • 39
    • 0024345465 scopus 로고
    • Two type II keratin genes are localized on human chromosome 12
    • Popsecu NC, Bowden PE, DiPaola JA (1989) Two type II keratin genes are localized on human chromosome 12. Hum Genet 82:109-112
    • (1989) Hum Genet , vol.82 , pp. 109-112
    • Popsecu, N.C.1    Bowden, P.E.2    DiPaola, J.A.3
  • 40
    • 0029670060 scopus 로고    scopus 로고
    • Gene targeting at the mouse cytokeratin 10 locus: Severe skin fragility and changes of cytokeratin expression in the epidermis
    • Porter RM, Leitgeb S, Melton DW, Swensson O, Eady RAJ, Magin TM (1996) Gene targeting at the mouse cytokeratin 10 locus: severe skin fragility and changes of cytokeratin expression in the epidermis. J Cell Biol 132:925-936
    • (1996) J Cell Biol , vol.132 , pp. 925-936
    • Porter, R.M.1    Leitgeb, S.2    Melton, D.W.3    Swensson, O.4    Eady, R.A.J.5    Magin, T.M.6
  • 41
    • 0025217859 scopus 로고
    • Cyclic hair loss and regrowth in transgenic mice overexpressing an intermediate filament gene
    • Powell BC, Rogers GE (1990) Cyclic hair loss and regrowth in transgenic mice overexpressing an intermediate filament gene. EMBO J 9:1485-1493
    • (1990) EMBO J , vol.9 , pp. 1485-1493
    • Powell, B.C.1    Rogers, G.E.2
  • 42
    • 0028844205 scopus 로고
    • Keratin 13 point mutation underlies the hereditary mucosal epithelia disorder white sponge nevus
    • Richard G, De Laurenzi V, Didona B, Bale SJ, Compton JG (1995) Keratin 13 point mutation underlies the hereditary mucosal epithelia disorder white sponge nevus. Nat Genet 11:453-455
    • (1995) Nat Genet , vol.11 , pp. 453-455
    • Richard, G.1    De Laurenzi, V.2    Didona, B.3    Bale, S.J.4    Compton, J.G.5
  • 43
    • 0028902751 scopus 로고
    • Defects in the barrier
    • Roop DR (1995) Defects in the barrier: Science 267:474-475
    • (1995) Science , vol.267 , pp. 474-475
    • Roop, D.R.1
  • 46
    • 0026110473 scopus 로고
    • A human epidermal differentiation-specific keratin gene is regulated by calcium but not negative modulators of differentiation in transgenic mouse keratinocytes
    • Rosenthal DS, Steinert PM, Chumg S, Huff CA, Johnson J, Yuspa SH, Roop DR (1991) A human epidermal differentiation-specific keratin gene is regulated by calcium but not negative modulators of differentiation in transgenic mouse keratinocytes. Cell Growth Differ 2:107-113
    • (1991) Cell Growth Differ , vol.2 , pp. 107-113
    • Rosenthal, D.S.1    Steinert, P.M.2    Chumg, S.3    Huff, C.A.4    Johnson, J.5    Yuspa, S.H.6    Roop, D.R.7
  • 47
    • 0000245779 scopus 로고
    • Analysis, diagnosis, and molecular genetics of keratin disorders
    • Rothnagel JA, Roop DR (1995) Analysis, diagnosis, and molecular genetics of keratin disorders. Curr Opin Dermatol 1995:211-218
    • (1995) Curr Opin Dermatol , vol.1995 , pp. 211-218
    • Rothnagel, J.A.1    Roop, D.R.2
  • 55
    • 0023613128 scopus 로고
    • Keratins of the human hair follicle: "hyperproliferative" keratins consistently expressed in outer root sheath cells in vivo and in vitro
    • Stark H-J, Breitkreutz D, Limat A, Bowden P, Fusenig NE (1987) Keratins of the human hair follicle: "hyperproliferative" keratins consistently expressed in outer root sheath cells in vivo and in vitro. Differentiation 35:236-248
    • (1987) Differentiation , vol.35 , pp. 236-248
    • Stark, H.-J.1    Breitkreutz, D.2    Limat, A.3    Bowden, P.4    Fusenig, N.E.5
  • 56
    • 0023951297 scopus 로고
    • Molecular and cellular biology of intermediate filaments
    • Steinert PM, Roop DR (1988) Molecular and cellular biology of intermediate filaments. Annu Rev Biochem 57:593-625
    • (1988) Annu Rev Biochem , vol.57 , pp. 593-625
    • Steinert, P.M.1    Roop, D.R.2
  • 57
    • 0028109866 scopus 로고
    • Increased expression of keratin 16 causes anomalies in cytoarchitecture and keratinization in transgenic mouse skin
    • Takahashi K, Folmer J, Coulombe PA (1994) Increased expression of keratin 16 causes anomalies in cytoarchitecture and keratinization in transgenic mouse skin. J Cell Biol 127:505-520
    • (1994) J Cell Biol , vol.127 , pp. 505-520
    • Takahashi, K.1    Folmer, J.2    Coulombe, P.A.3
  • 59
    • 0009482260 scopus 로고
    • Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
    • Towbin H, Staehelin T, Gordon J (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci USA 76:4350-4354
    • (1979) Proc Natl Acad Sci USA , vol.76 , pp. 4350-4354
    • Towbin, H.1    Staehelin, T.2    Gordon, J.3
  • 60
    • 0025976155 scopus 로고
    • Mutant keratin expression in transgenic mice causes marked abnormalities resembling a human genetic skin disease
    • Vassar R, Coulombe PA, Degenstein L, Albers K, Fuchs E (1991) Mutant keratin expression in transgenic mice causes marked abnormalities resembling a human genetic skin disease. Cell 64:365-380
    • (1991) Cell , vol.64 , pp. 365-380
    • Vassar, R.1    Coulombe, P.A.2    Degenstein, L.3    Albers, K.4    Fuchs, E.5
  • 61
    • 0021223740 scopus 로고
    • Monoclonal antibody analysis of keratin expression in eidermal diseases: A 48- and 56-Kdalton keratin as molecular markers for hyperproliferative keratinocytes
    • Weiss RA, Eichner R, Sun T-T (1984) Monoclonal antibody analysis of keratin expression in eidermal diseases: a 48- and 56-Kdalton keratin as molecular markers for hyperproliferative keratinocytes. J Cell Biol 98:1397-1406
    • (1984) J Cell Biol , vol.98 , pp. 1397-1406
    • Weiss, R.A.1    Eichner, R.2    Sun, T.-T.3
  • 62
    • 0013941372 scopus 로고
    • An electron microscopic study of epidermolytic hyperkeratosis
    • Wilgram GF, Caulfield JB (1966) An electron microscopic study of epidermolytic hyperkeratosis. Arch Dermatol 94:127-143
    • (1966) Arch Dermatol , vol.94 , pp. 127-143
    • Wilgram, G.F.1    Caulfield, J.B.2
  • 63
    • 0020368610 scopus 로고
    • Immunolocalization of keratin polypeptides in human epidermis using monoclonal antibodies
    • Woodcock-Mitchell JR, Eichner R, Nelson WG, Sun T-T (1982) Immunolocalization of keratin polypeptides in human epidermis using monoclonal antibodies. J Cell Biol 95:580-588
    • (1982) J Cell Biol , vol.95 , pp. 580-588
    • Woodcock-Mitchell, J.R.1    Eichner, R.2    Nelson, W.G.3    Sun, T.-T.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.