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Volumn 85, Issue 3, 2000, Pages 237-243

Modification of alternative splicing pathways as a potential approach to chemotherapy

Author keywords

Alternative splicing; Antisense oligonucleotides; Cancer chemotherapy; Genetic disorders; RNA splicing

Indexed keywords

ANTINEOPLASTIC AGENT; ANTISENSE OLIGONUCLEOTIDE; CASPASE 2; CATHEPSIN B; HERMES ANTIGEN; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL X; PROTEIN P73;

EID: 0034065833     PISSN: 01637258     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0163-7258(99)00067-4     Document Type: Conference Paper
Times cited : (69)

References (51)
  • 1
    • 0032575688 scopus 로고    scopus 로고
    • The Bcl-2 protein family: Arbiters of cell survival
    • Adams J.M., Cory S. The Bcl-2 protein family. arbiters of cell survival Science. 281:1998;1322-1326.
    • (1998) Science , vol.281 , pp. 1322-1326
    • Adams, J.M.1    Cory, S.2
  • 2
    • 0029024368 scopus 로고
    • Mapping of the human BAX gene to chromosome 19q13.3-q13.4 and isolation of a novel alternatively spliced transcript, BAX delta
    • Apte S.S., Mattei M.G., Olsen B.R. Mapping of the human BAX gene to chromosome 19q13.3-q13.4 and isolation of a novel alternatively spliced transcript, BAX delta. Genomics. 26:1995;592-594.
    • (1995) Genomics , vol.26 , pp. 592-594
    • Apte, S.S.1    Mattei, M.G.2    Olsen, B.R.3
  • 3
    • 0033152121 scopus 로고    scopus 로고
    • Increased level of exon 12 alternatively spliced BRCA2 transcripts in tumor breast tissue compared with normal tissue
    • Bieche I., Lidereau R. Increased level of exon 12 alternatively spliced BRCA2 transcripts in tumor breast tissue compared with normal tissue. Cancer Res. 59:1999;2546-2550.
    • (1999) Cancer Res , vol.59 , pp. 2546-2550
    • Bieche, I.1    Lidereau, R.2
  • 6
    • 0032532734 scopus 로고    scopus 로고
    • WT1 interacts with the splicing factor U2AF65 in an isoform dependent manner and can be incorporated into spliceosomes
    • Davies R.C., Calvo C., Bratt E., Larsson S., Lamond A.I., Hastie N.D. WT1 interacts with the splicing factor U2AF65 in an isoform dependent manner and can be incorporated into spliceosomes. Genes Dev. 12:1998;3217-3225.
    • (1998) Genes Dev , vol.12 , pp. 3217-3225
    • Davies, R.C.1    Calvo, C.2    Bratt, E.3    Larsson, S.4    Lamond, A.I.5    Hastie, N.D.6
  • 8
    • 0032998309 scopus 로고    scopus 로고
    • Overcoming bcl-2 and p53 mediated resistance in prostate cancer
    • DiPaola R.S., Aisner J. Overcoming bcl-2 and p53 mediated resistance in prostate cancer. Semin Oncol. 26:1999;112-116.
    • (1999) Semin Oncol , vol.26 , pp. 112-116
    • Dipaola, R.S.1    Aisner, J.2
  • 9
    • 0033595614 scopus 로고    scopus 로고
    • Genetic alterations in early-onset invasive breast carcinomas: Correlation of c-erbB-2 amplification detected by fluorescence in situ hybridization with p53 accumulation and tumor phenotype
    • Fiche M., Avet-Loiseau H., Heymann M.F., Moussaly F., Digabel C., Joubert M., Classe J.M., Dravet F., Fumoleau P., Ross J., Maugard C.M. Genetic alterations in early-onset invasive breast carcinomas. correlation of c-erbB-2 amplification detected by fluorescence in situ hybridization with p53 accumulation and tumor phenotype Int J Cancer. 84:1999;511-515.
    • (1999) Int J Cancer , vol.84 , pp. 511-515
    • Fiche, M.1    Avet-Loiseau, H.2    Heymann, M.F.3    Moussaly, F.4    Digabel, C.5    Joubert, M.6    Classe, J.M.7    Dravet, F.8    Fumoleau, P.9    Ross, J.10    Maugard, C.M.11
  • 11
    • 0033024272 scopus 로고    scopus 로고
    • Up-regulation of ICH-1L protein by thromboxane A2 antagonists enhances cisplatin-induced apoptosis in non-small cell lung cancer cell lines
    • Fujimura M., Kasahara K., Shirasaki H., Heki U., Iwasa K., Ueda A., Matsuda T. Up-regulation of ICH-1L protein by thromboxane A2 antagonists enhances cisplatin-induced apoptosis in non-small cell lung cancer cell lines. J Cancer Res Clin Oncol. 125:1999;389-394.
    • (1999) J Cancer Res Clin Oncol , vol.125 , pp. 389-394
    • Fujimura, M.1    Kasahara, K.2    Shirasaki, H.3    Heki, U.4    Iwasa, K.5    Ueda, A.6    Matsuda, T.7
  • 15
    • 0032791736 scopus 로고    scopus 로고
    • Adhesion proteins in the biology of breast cancer: Contribution of CD44
    • Herrera-Gayol A., Jothy S. Adhesion proteins in the biology of breast cancer. contribution of CD44 Exp Mol Pathol. 66:1999;149-156.
    • (1999) Exp Mol Pathol , vol.66 , pp. 149-156
    • Herrera-Gayol, A.1    Jothy, S.2
  • 16
    • 0026002788 scopus 로고
    • CD44 splice variants confer metastatic behavior in rats: Homologous sequences are expressed in human tumor cell lines
    • Hofmann M., Ruddy W., Zoller M., Tolg C., Ponta H., Herrlich P., Gunthert U. CD44 splice variants confer metastatic behavior in rats. homologous sequences are expressed in human tumor cell lines Cancer Res. 51:1991;5292-5297.
    • (1991) Cancer Res , vol.51 , pp. 5292-5297
    • Hofmann, M.1    Ruddy, W.2    Zoller, M.3    Tolg, C.4    Ponta, H.5    Herrlich, P.6    Gunthert, U.7
  • 17
  • 18
    • 0033048446 scopus 로고    scopus 로고
    • Decreased expression of bax is correlated with poor prognosis in oral and oropharyngeal carcinoma
    • Ito T., Fujieda S., Tsuzuki H., Sunaga H., Fan G., Sugimoto C., Fukuda M., Saito H. Decreased expression of bax is correlated with poor prognosis in oral and oropharyngeal carcinoma. Cancer Lett. 140:1999;81-91.
    • (1999) Cancer Lett , vol.140 , pp. 81-91
    • Ito, T.1    Fujieda, S.2    Tsuzuki, H.3    Sunaga, H.4    Fan, G.5    Sugimoto, C.6    Fukuda, M.7    Saito, H.8
  • 19
    • 0032914182 scopus 로고    scopus 로고
    • Alternative splicing and programmed cell death
    • Jiang Z.H., Wu J.Y. Alternative splicing and programmed cell death. Proc Soc Exp Biol Med. 220:1999;64-72.
    • (1999) Proc Soc Exp Biol Med , vol.220 , pp. 64-72
    • Jiang, Z.H.1    Wu, J.Y.2
  • 20
    • 0344766067 scopus 로고    scopus 로고
    • The emerging p53 gene family
    • Kaelin W.G. Jr. The emerging p53 gene family. J Natl Cancer Inst. 91:1999;594-598.
    • (1999) J Natl Cancer Inst , vol.91 , pp. 594-598
    • Kaelin W.G., Jr.1
  • 21
    • 0029953670 scopus 로고    scopus 로고
    • Cathepsin B: Multiple enzyme forms from a single gene and their relation to cancer
    • Keppler D., Sloane B.F. Cathepsin B. multiple enzyme forms from a single gene and their relation to cancer Enzyme Protein. 49:1996;94-105.
    • (1996) Enzyme Protein , vol.49 , pp. 94-105
    • Keppler, D.1    Sloane, B.F.2
  • 22
    • 0029972806 scopus 로고    scopus 로고
    • P53: Puzzle and paradigm
    • Ko J.K., Prives C. P53. puzzle and paradigm Genes Dev. 10:1996;1054-1072.
    • (1996) Genes Dev , vol.10 , pp. 1054-1072
    • Ko, J.K.1    Prives, C.2
  • 23
    • 0003009802 scopus 로고    scopus 로고
    • Modification of pre-mRNA splicing by antisense oligonucleotides
    • C.A. Stein, & A.M. Krieg. New York: Willey-Liss, Inc
    • Kole R. Modification of pre-mRNA splicing by antisense oligonucleotides. Stein C.A., Krieg A.M. Applied Antisense Oligonucleotide Technology. 1998;451-469 Willey-Liss, Inc, New York.
    • (1998) Applied Antisense Oligonucleotide Technology , pp. 451-469
    • Kole, R.1
  • 24
    • 0027523091 scopus 로고
    • Activated human lymphocytes and aggressive non-Hodgkin's lymphoma express a homologue of the rat metastasis-associated variant of CD44
    • Koopman G., Heider K.H., Horst E., Adolf G.R., van den Berg F., Ponta H., Herrlich P., Pals S.T. Activated human lymphocytes and aggressive non-Hodgkin's lymphoma express a homologue of the rat metastasis-associated variant of CD44. J Exp Med. 177:1993;897-904.
    • (1993) J Exp Med , vol.177 , pp. 897-904
    • Koopman, G.1    Heider, K.H.2    Horst, E.3    Adolf, G.R.4    Van Den Berg, F.5    Ponta, H.6    Herrlich, P.7    Pals, S.T.8
  • 25
    • 0026794668 scopus 로고
    • The mutational spectrum of single base-pair substitutions in mRNA splice junctions of human genes: Causes and consequences
    • Krawczak M., Reiss J., Cooper D.N. The mutational spectrum of single base-pair substitutions in mRNA splice junctions of human genes. causes and consequences Hum Genet. 90:1992;41-54.
    • (1992) Hum Genet , vol.90 , pp. 41-54
    • Krawczak, M.1    Reiss, J.2    Cooper, D.N.3
  • 26
    • 0029888125 scopus 로고    scopus 로고
    • Overexpression of HER2 modulates Bcl-2, Bcl-xl, and tamoxifen-induced apoptosis in human MCF-7 breast cancer cells
    • Kumar R., Mandal M., Lipton A., Harvey H., Thompson C.B. Overexpression of HER2 modulates Bcl-2, Bcl-xl, and tamoxifen-induced apoptosis in human MCF-7 breast cancer cells. Clin Cancer Res. 2:1996;1215-1219.
    • (1996) Clin Cancer Res , vol.2 , pp. 1215-1219
    • Kumar, R.1    Mandal, M.2    Lipton, A.3    Harvey, H.4    Thompson, C.B.5
  • 27
    • 0033022485 scopus 로고    scopus 로고
    • Low rate of apoptosis and overexpression of bcl-2 in Epstein Barr virus associated gastric carcinoma
    • Kume T., Oshima K., Shinohara T., Takeo H., Yamashita Y., Shirakusa T., Kikuchi M. Low rate of apoptosis and overexpression of bcl-2 in Epstein Barr virus associated gastric carcinoma. Histopathology. 34:1999;502-509.
    • (1999) Histopathology , vol.34 , pp. 502-509
    • Kume, T.1    Oshima, K.2    Shinohara, T.3    Takeo, H.4    Yamashita, Y.5    Shirakusa, T.6    Kikuchi, M.7
  • 29
    • 0031921306 scopus 로고    scopus 로고
    • The Wilms' tumor gene: Oncogene or tumor suppressor gene?
    • Menke A.L., Van der Eb A.J., Jochemsen A.G. The Wilms' tumor gene. oncogene or tumor suppressor gene? Int Rev Cytol. 181:1998;151-212.
    • (1998) Int Rev Cytol , vol.181 , pp. 151-212
    • Menke, A.L.1    Van Der Eb, A.J.2    Jochemsen, A.G.3
  • 30
    • 0029874986 scopus 로고    scopus 로고
    • Bcl-x(S) antagonizes the protective effects of Bcl-x(L)
    • Minn A.J., Boise L.H., Thompson C.B. Bcl-x(S) antagonizes the protective effects of Bcl-x(L). J Biol Chem. 71:1996;6306-6312.
    • (1996) J Biol Chem , vol.71 , pp. 6306-6312
    • Minn, A.J.1    Boise, L.H.2    Thompson, C.B.3
  • 33
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
    • Oltvai Z.N., Milliman C.L., Korsmeyer S.J. Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell. 74:1993;609-619.
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3
  • 34
    • 0032780820 scopus 로고    scopus 로고
    • The Wilms tumour gene, WT1, in normal and abnormal nephrogenesis
    • Pritchard-Jones K. The Wilms tumour gene, WT1, in normal and abnormal nephrogenesis. Pediatr Nephrol. 13:1999;620-625.
    • (1999) Pediatr Nephrol , vol.13 , pp. 620-625
    • Pritchard-Jones, K.1
  • 35
    • 0033014030 scopus 로고    scopus 로고
    • In vivo patterns of BCl-2 family protein expression in breast carcinomas in relations to apoptosis
    • Rochaix P., Krajewski S., Reed J.C., Bonnet F., Voigt J.J., Brousset P. In vivo patterns of BCl-2 family protein expression in breast carcinomas in relations to apoptosis. J Pathol. 187:1999;410-415.
    • (1999) J Pathol , vol.187 , pp. 410-415
    • Rochaix, P.1    Krajewski, S.2    Reed, J.C.3    Bonnet, F.4    Voigt, J.J.5    Brousset, P.6
  • 36
    • 0029909361 scopus 로고    scopus 로고
    • Fas splicing, variants and their effect on apoptosis
    • Ruberti G., Cascino I., Papoff G., Eramo A. Fas splicing, variants and their effect on apoptosis. Adv Exp Med Biol. 406:1996;125-134.
    • (1996) Adv Exp Med Biol , vol.406 , pp. 125-134
    • Ruberti, G.1    Cascino, I.2    Papoff, G.3    Eramo, A.4
  • 37
    • 0342699025 scopus 로고    scopus 로고
    • Effects of oligonucleotide backbones on cellular uptake and antisense modification of splicing pathways
    • Schmajuk G.H., Sierakowska H., Kole R. Effects of oligonucleotide backbones on cellular uptake and antisense modification of splicing pathways. J Biol Chem. 274:1999;1783-1789.
    • (1999) J Biol Chem , vol.274 , pp. 1783-1789
    • Schmajuk, G.H.1    Sierakowska, H.2    Kole, R.3
  • 38
    • 0032996268 scopus 로고    scopus 로고
    • Molecular genetic analysis of primary lung cancer and cancer metastatic to the lung
    • Schreiber G., Pitterle D., Kim Y.C., Bepler G. Molecular genetic analysis of primary lung cancer and cancer metastatic to the lung. Anticancer Res. 19:1999;1109-1115.
    • (1999) Anticancer Res , vol.19 , pp. 1109-1115
    • Schreiber, G.1    Pitterle, D.2    Kim, Y.C.3    Bepler, G.4
  • 39
    • 0029803547 scopus 로고    scopus 로고
    • Repair of thalassemic human β-globin mRNA in mammalian cells by antisense oligonucleotides
    • Sierakowska H., Sambade M.J., Agrawal S., Kole R. Repair of thalassemic human β-globin mRNA in mammalian cells by antisense oligonucleotides. Proc Natl Acad Sci USA. 93:1996;12840-12844.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 12840-12844
    • Sierakowska, H.1    Sambade, M.J.2    Agrawal, S.3    Kole, R.4
  • 40
    • 0033991047 scopus 로고    scopus 로고
    • Antisense oligonucleotides and RNAs as modulators of pre-mRNA splicing
    • Sierakowska H., Gorman L., Kang S.H., Kole R. Antisense oligonucleotides and RNAs as modulators of pre-mRNA splicing. Methods Enzymol. 313:1999;506-521.
    • (1999) Methods Enzymol , vol.313 , pp. 506-521
    • Sierakowska, H.1    Gorman, L.2    Kang, S.H.3    Kole, R.4
  • 41
    • 0031874645 scopus 로고    scopus 로고
    • The normal structure and function of CD44 and its role in neoplasia
    • Sneath R.J., Mangham D.C. The normal structure and function of CD44 and its role in neoplasia. Mol Pathol. 51:1998;191-200.
    • (1998) Mol Pathol , vol.51 , pp. 191-200
    • Sneath, R.J.1    Mangham, D.C.2
  • 42
    • 0028979438 scopus 로고
    • Overexpression of Bcl-xS sensitizes MCF-7 cells to chemotherapy-induced apoptosis
    • Sumantran V.N., Ealovega M.W., Nunez G., Clarke M.F., Wicha M.S. Overexpression of Bcl-xS sensitizes MCF-7 cells to chemotherapy-induced apoptosis. Cancer Res. 55:1995;2507-2510.
    • (1995) Cancer Res , vol.55 , pp. 2507-2510
    • Sumantran, V.N.1    Ealovega, M.W.2    Nunez, G.3    Clarke, M.F.4    Wicha, M.S.5
  • 43
    • 0022546957 scopus 로고
    • Analysis of the structure, transcripts, and protein products of bcl-2, the gene involved in human follicular lymphoma
    • Tsujimoto Y., Croce C.M. Analysis of the structure, transcripts, and protein products of bcl-2, the gene involved in human follicular lymphoma. Proc Natl Acad Sci USA. 83:1986;5214-5218.
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 5214-5218
    • Tsujimoto, Y.1    Croce, C.M.2
  • 44
    • 0032937404 scopus 로고    scopus 로고
    • Modulation of the immune response and tumor growth by activated Ras
    • Weijzen S., Velders M.P., Kast W.M. Modulation of the immune response and tumor growth by activated Ras. Leukemia. 13:1999;502-513.
    • (1999) Leukemia , vol.13 , pp. 502-513
    • Weijzen, S.1    Velders, M.P.2    Kast, W.M.3
  • 45
    • 0032833801 scopus 로고    scopus 로고
    • Involvement of the c-erbB-2 oncogene product in the egf-induced cell motility of sk-ov-3 ovarian cancer cells
    • Wiechen K., Karaaslan S., Dietel M. Involvement of the c-erbB-2 oncogene product in the egf-induced cell motility of sk-ov-3 ovarian cancer cells. Int J Cancer. 83:1999;409-414.
    • (1999) Int J Cancer , vol.83 , pp. 409-414
    • Wiechen, K.1    Karaaslan, S.2    Dietel, M.3
  • 46
  • 49
    • 0033125727 scopus 로고    scopus 로고
    • Antisense bcl-2 retrovirus vector increases the sensitivity of a human gastric adenocarcinoma cell line to photodynamic therapy
    • Zhang W.G., Ma L.P., Wang S.W., Zhang Z.Y., Cao G.D. Antisense bcl-2 retrovirus vector increases the sensitivity of a human gastric adenocarcinoma cell line to photodynamic therapy. Photochem Photobiol. 69:1999;582-586.
    • (1999) Photochem Photobiol , vol.69 , pp. 582-586
    • Zhang, W.G.1    Ma, L.P.2    Wang, S.W.3    Zhang, Z.Y.4    Cao, G.D.5
  • 50
    • 0033088695 scopus 로고    scopus 로고
    • Development and application of adenoviral vectors for gene therapy of cancer
    • Zhang W.W. Development and application of adenoviral vectors for gene therapy of cancer. Cancer Gene Ther. 6:1999;113-138.
    • (1999) Cancer Gene Ther , vol.6 , pp. 113-138
    • Zhang, W.W.1
  • 51
    • 0032496238 scopus 로고    scopus 로고
    • A novel splice variant of the cell death-promoting protein Bax
    • Zhou M., Demo S.D., McClure T.N., Crea R., Bitler C.M. A novel splice variant of the cell death-promoting protein Bax. J Biol Chem. 273:1998;11930-11936.
    • (1998) J Biol Chem , vol.273 , pp. 11930-11936
    • Zhou, M.1    Demo, S.D.2    McClure, T.N.3    Crea, R.4    Bitler, C.M.5


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