메뉴 건너뛰기




Volumn 26, Issue 5, 2000, Pages 417-422

Gap junctions and biophysical regulation of bone cell differentiation

Author keywords

Calcium; Connexins; Fluid flow; Mechanotransduction; Osteoblasts; Osteocytes

Indexed keywords

BONE TURNOVER; CELL DIFFERENTIATION; CELL JUNCTION; HUMAN; MECHANICAL STRESS; REVIEW; SIGNAL TRANSDUCTION;

EID: 0034037735     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/S8756-3282(00)00245-3     Document Type: Article
Times cited : (169)

References (93)
  • 3
    • 0000675802 scopus 로고    scopus 로고
    • Monoclonal antibodies as tools for studying the osteoblast lineage [review]
    • Aubin J.E., Turksen K. Monoclonal antibodies as tools for studying the osteoblast lineage [review]. Microsc Res Techn. 33:1996;128-140.
    • (1996) Microsc Res Techn , vol.33 , pp. 128-140
    • Aubin, J.E.1    Turksen, K.2
  • 4
    • 79960138906 scopus 로고    scopus 로고
    • Equibiaxial strain activates AP-1 and CRE transcription factors but not NF-κB or SSRE and upregulates Cx43 mRNA in tendon cells in vitro
    • New Orleans, LA, 1998. Rosemont, IL: Orthopedic Research Society;
    • Banes, A. J., Tsuzaki, M., Yang, X., Faber, J., Bottlang, M., Pederson, D., and Brown, T. Equibiaxial strain activates AP-1 and CRE transcription factors but not NF-κB or SSRE and upregulates Cx43 mRNA in tendon cells in vitro. In: Proceedings of the 44th Annual Meeting of the Orthopedic Research Society, New Orleans, LA, 1998. Rosemont, IL: Orthopedic Research Society; 1998.
    • (1998) In: Proceedings of the 44th Annual Meeting of the Orthopedic Research Society
    • Banes, A.J.1    Tsuzaki, M.2    Yang, X.3    Faber, J.4    Bottlang, M.5    Pederson, D.6    Brown, T.7
  • 5
    • 0024592298 scopus 로고
    • Antisera directed against connexin43 peptides react with a 43-kD protein localized to gap junctions in myocardium and other tissues
    • Beyer E.C., Kistler J., Paul D.L., Goodenough D.A. Antisera directed against connexin43 peptides react with a 43-kD protein localized to gap junctions in myocardium and other tissues. J Cell Biol. 108:1989;595-605.
    • (1989) J Cell Biol , vol.108 , pp. 595-605
    • Beyer, E.C.1    Kistler, J.2    Paul, D.L.3    Goodenough, D.A.4
  • 6
    • 0023551497 scopus 로고
    • Connexin43: A protein from rat heart homologous to a gap junction protein from liver
    • Beyer E.C., Paul D.L., Goodenough D.A. Connexin43 A protein from rat heart homologous to a gap junction protein from liver . J Cell Biol. 105:1987;2621-2629.
    • (1987) J Cell Biol , vol.105 , pp. 2621-2629
    • Beyer, E.C.1    Paul, D.L.2    Goodenough, D.A.3
  • 7
    • 0026322846 scopus 로고
    • The proliferative and synthetic response of isolated calvarial bone cells of rat to cyclic mechanical strain
    • Brighton C.T., Strafford B., Gross S.B., Leatherwood D.F., Williams J.L., Pollack S.R. The proliferative and synthetic response of isolated calvarial bone cells of rat to cyclic mechanical strain. J Bone Jt Surg. 73-A:1991;320-331.
    • (1991) J Bone Jt Surg , vol.73 , pp. 320-331
    • Brighton, C.T.1    Strafford, B.2    Gross, S.B.3    Leatherwood, D.F.4    Williams, J.L.5    Pollack, S.R.6
  • 8
    • 0025312102 scopus 로고
    • The effects of mechanical strain on osteoblasts in vitro
    • Buckley M.J., Banes A.J., Jordan R.D. The effects of mechanical strain on osteoblasts in vitro. J Oral Maxillofac Surg. 48:1990;276-282.
    • (1990) J Oral Maxillofac Surg , vol.48 , pp. 276-282
    • Buckley, M.J.1    Banes, A.J.2    Jordan, R.D.3
  • 10
    • 0031904354 scopus 로고    scopus 로고
    • Osteoblasts induce osteopontin expression in response to attachment on fibronectin: Demonstration of a common role for integrin receptors in the signal transduction processes of cell attachment and mechanical stimulation
    • Carvalho R.S., Schaffer J.L., Gerstenfeld L.C. Osteoblasts induce osteopontin expression in response to attachment on fibronectin Demonstration of a common role for integrin receptors in the signal transduction processes of cell attachment and mechanical stimulation . J Cell Biochem. 70:1998;376-390.
    • (1998) J Cell Biochem , vol.70 , pp. 376-390
    • Carvalho, R.S.1    Schaffer, J.L.2    Gerstenfeld, L.C.3
  • 11
    • 0028290242 scopus 로고
    • Hormonal regulation of connexin 43 expression and gap junctional communication in human osteoblastic cells
    • Chiba H., Sawada N., Oyamada M., Kojima T., Iba K., Ishii S., Mori M. Hormonal regulation of connexin 43 expression and gap junctional communication in human osteoblastic cells. Cell Struct Funct. 19:1994;173-177.
    • (1994) Cell Struct Funct , vol.19 , pp. 173-177
    • Chiba, H.1    Sawada, N.2    Oyamada, M.3    Kojima, T.4    Iba, K.5    Ishii, S.6    Mori, M.7
  • 12
    • 0027850391 scopus 로고
    • Relationship between the expression of the gap junction protein and osteoblast phenotype in a human osteoblastic cell line during cell proliferation
    • Chiba H., Sawada N., Oyamada M., Kojima T., Nomura S., Ishii S., Mori M. Relationship between the expression of the gap junction protein and osteoblast phenotype in a human osteoblastic cell line during cell proliferation. Cell Struct Funct. 18:1993;419-426.
    • (1993) Cell Struct Funct , vol.18 , pp. 419-426
    • Chiba, H.1    Sawada, N.2    Oyamada, M.3    Kojima, T.4    Nomura, S.5    Ishii, S.6    Mori, M.7
  • 13
    • 0030059561 scopus 로고    scopus 로고
    • Mechanical stimulation initiates cell-to-cell calcium signaling in ovine lens epithelial cells
    • Churchill G.C., Atkinson M.M., Louis C.F. Mechanical stimulation initiates cell-to-cell calcium signaling in ovine lens epithelial cells. J Cell Sci. 109:1996;355-365.
    • (1996) J Cell Sci , vol.109 , pp. 355-365
    • Churchill, G.C.1    Atkinson, M.M.2    Louis, C.F.3
  • 15
    • 0026546253 scopus 로고
    • Heterogeneous intracellular free calcium responses to parathyroid hormone correlate with morphology and receptor distribution in osteogenic sarcoma cells
    • Civitelli R., Fujimori A., Bernier S.M., Warlow P.M., Goltzman D., Hruska K.A., Avioli L.V. Heterogeneous intracellular free calcium responses to parathyroid hormone correlate with morphology and receptor distribution in osteogenic sarcoma cells. Endocrinology. 130:1992;2392-2400.
    • (1992) Endocrinology , vol.130 , pp. 2392-2400
    • Civitelli, R.1    Fujimori, A.2    Bernier, S.M.3    Warlow, P.M.4    Goltzman, D.5    Hruska, K.A.6    Avioli, L.V.7
  • 18
    • 0032550290 scopus 로고    scopus 로고
    • Regulation of vascular connexin43 gene expression by mechanical loads
    • Cowan D.B., Lye S.J., Langille B.L. Regulation of vascular connexin43 gene expression by mechanical loads. Circ Res. 82:1998;786-793.
    • (1998) Circ Res , vol.82 , pp. 786-793
    • Cowan, D.B.1    Lye, S.J.2    Langille, B.L.3
  • 19
    • 0031859351 scopus 로고    scopus 로고
    • The estrogen receptor's involvement in osteoblasts' adaptive response to mechanical strain
    • Damien E., Price J.S., Lanyon L.E. The estrogen receptor's involvement in osteoblasts' adaptive response to mechanical strain. J Bone Miner Res. 13:1998;1275-1282.
    • (1998) J Bone Miner Res , vol.13 , pp. 1275-1282
    • Damien, E.1    Price, J.S.2    Lanyon, L.E.3
  • 20
    • 0029827231 scopus 로고    scopus 로고
    • Gap junctions mediate intercellular calcium signalling in cultured articular chondrocytes
    • D'Andrea P., Vittur F. Gap junctions mediate intercellular calcium signalling in cultured articular chondrocytes. Cell Calcium. 20:1996;389-397.
    • (1996) Cell Calcium , vol.20 , pp. 389-397
    • D'Andrea, P.1    Vittur, F.2
  • 22
    • 0034095163 scopus 로고    scopus 로고
    • Differentiation of human fetal osteoblastic cells is partially dependent on gap junctional intercellular communication
    • Donahue H.J., Li Z., Zhou Z., Yellowley C.E. Differentiation of human fetal osteoblastic cells is partially dependent on gap junctional intercellular communication. Am J Physiol. 278:2000;C315-C322.
    • (2000) Am J Physiol , vol.278
    • Donahue, H.J.1    Li, Z.2    Zhou, Z.3    Yellowley, C.E.4
  • 23
    • 0029015765 scopus 로고
    • Cell-to-cell communication in osteoblastic networks: Cell line-dependent hormonal regulation of gap junction function
    • Donahue H.J., McLeod K.J., Rubin C.T., Andersen J., Grine E.A., Hertzberg E.L., Brink P.R. Cell-to-cell communication in osteoblastic networks Cell line-dependent hormonal regulation of gap junction function . J Bone Miner Res. 10:1995;881-889.
    • (1995) J Bone Miner Res , vol.10 , pp. 881-889
    • Donahue, H.J.1    McLeod, K.J.2    Rubin, C.T.3    Andersen, J.4    Grine, E.A.5    Hertzberg, E.L.6    Brink, P.R.7
  • 24
    • 0019774348 scopus 로고
    • Morphological evidence of gap junctions between bone cells
    • Doty S.B. Morphological evidence of gap junctions between bone cells. Calcif Tissue Int. 33:1981;509-512.
    • (1981) Calcif Tissue Int , vol.33 , pp. 509-512
    • Doty, S.B.1
  • 25
    • 0028807366 scopus 로고
    • Mechanotransduction and the functional response of bone to mechanical strain [review]
    • Duncan R.L., Turner C.H. Mechanotransduction and the functional response of bone to mechanical strain [review]. Calcif Tissue Int. 57:1995;344-358.
    • (1995) Calcif Tissue Int , vol.57 , pp. 344-358
    • Duncan, R.L.1    Turner, C.H.2
  • 26
    • 0030579070 scopus 로고    scopus 로고
    • Gravitational loading of a simulated launch alters mRNA expression in osteoblasts
    • Fitzgerald J., Hughes-Fulford M. Gravitational loading of a simulated launch alters mRNA expression in osteoblasts. Exp Cell Res. 228:1996;168-171.
    • (1996) Exp Cell Res , vol.228 , pp. 168-171
    • Fitzgerald, J.1    Hughes-Fulford, M.2
  • 27
    • 0001406145 scopus 로고
    • On the piezoelectric effect of bone
    • Fukada E., Yasuda I. On the piezoelectric effect of bone. J Phys Soc. 12:1957;1158-1162.
    • (1957) J Phys Soc , vol.12 , pp. 1158-1162
    • Fukada, E.1    Yasuda, I.2
  • 28
    • 0032556026 scopus 로고    scopus 로고
    • Connexin43 is highly localized to sites of disturbed flow in rat aortic endothelium but connexin37 and connexin40 are more uniformly distributed [see comments]
    • Gabriels J.E., Paul D.L. Connexin43 is highly localized to sites of disturbed flow in rat aortic endothelium but connexin37 and connexin40 are more uniformly distributed [see comments]. Circ Res. 83:1998;636-643.
    • (1998) Circ Res , vol.83 , pp. 636-643
    • Gabriels, J.E.1    Paul, D.L.2
  • 29
    • 0028899672 scopus 로고
    • Human osteoblast-like cells respond to mechanical strain with increased bone matrix protein production independent of hormonal regulation
    • Harter L.V., Hruska K.A., Duncan R.L. Human osteoblast-like cells respond to mechanical strain with increased bone matrix protein production independent of hormonal regulation. Endocrinology. 136:1995;528-535.
    • (1995) Endocrinology , vol.136 , pp. 528-535
    • Harter, L.V.1    Hruska, K.A.2    Duncan, R.L.3
  • 30
  • 31
    • 0031031469 scopus 로고    scopus 로고
    • Alkaline phosphatase in osteoblasts is down-regulated by pulsatile fluid flow
    • Hillsley M.V., Frangos J.A. Alkaline phosphatase in osteoblasts is down-regulated by pulsatile fluid flow. Calcif Tissue Int. 60:1997;48-53.
    • (1997) Calcif Tissue Int , vol.60 , pp. 48-53
    • Hillsley, M.V.1    Frangos, J.A.2
  • 32
    • 0030296248 scopus 로고    scopus 로고
    • What is the role of the convective current density in the real-time calcium response of cultured bone cells to fluid flow?
    • Hung C.T., Allen F.D., Pollack S.R., Brighton C.T. What is the role of the convective current density in the real-time calcium response of cultured bone cells to fluid flow? J Biomech. 29:1996;1403-1409.
    • (1996) J Biomech , vol.29 , pp. 1403-1409
    • Hung, C.T.1    Allen, F.D.2    Pollack, S.R.3    Brighton, C.T.4
  • 34
    • 0032212080 scopus 로고    scopus 로고
    • Differential effect of steady versus oscillating flow on bone cells
    • Jacobs C.R., Yellowley C.E., Davis B.R., Zhou Z., Donahue H.J. Differential effect of steady versus oscillating flow on bone cells. J Biomech. 31:1998;969-976.
    • (1998) J Biomech , vol.31 , pp. 969-976
    • Jacobs, C.R.1    Yellowley, C.E.2    Davis, B.R.3    Zhou, Z.4    Donahue, H.J.5
  • 36
    • 0029841159 scopus 로고    scopus 로고
    • Fluid flow stimulates rapid and continuous release of nitric oxide in osteoblasts
    • Johnson D.L., McAllister T.N., Frangos J.A. Fluid flow stimulates rapid and continuous release of nitric oxide in osteoblasts. Am J Physiol Endocrinol Metab. 34:1996;E205-E208.
    • (1996) Am J Physiol Endocrinol Metab , vol.34
    • Johnson, D.L.1    McAllister, T.N.2    Frangos, J.A.3
  • 37
    • 0030776894 scopus 로고    scopus 로고
    • ATP- And gap junction-dependent intercellular calcium signaling in osteoblastic cells
    • Jorgensen N.R., Geist S.T., Civitelli R., Steinberg T.H. ATP- and gap junction-dependent intercellular calcium signaling in osteoblastic cells. J Cell Biol. 139:1997;497-506.
    • (1997) J Cell Biol , vol.139 , pp. 497-506
    • Jorgensen, N.R.1    Geist, S.T.2    Civitelli, R.3    Steinberg, T.H.4
  • 39
    • 0031765152 scopus 로고    scopus 로고
    • Stimulative effect of high-level hypergravity on differentiated functions of osteoblast-like cells
    • Kawashima K., Shibata R., Negishi Y., Endo H. Stimulative effect of high-level hypergravity on differentiated functions of osteoblast-like cells. Cell Struct Funct. 23:1998;221-229.
    • (1998) Cell Struct Funct , vol.23 , pp. 221-229
    • Kawashima, K.1    Shibata, R.2    Negishi, Y.3    Endo, H.4
  • 40
    • 0031039225 scopus 로고    scopus 로고
    • Mechanical stimulation of osteopontin mRNA expression and synthesis in bone cell cultures
    • Klein-Nulend J., Roelofsen J., Semeins C.M., Bronckers A.L., Burger E.H. Mechanical stimulation of osteopontin mRNA expression and synthesis in bone cell cultures. J Cell Physiol. 170:1997;174-181.
    • (1997) J Cell Physiol , vol.170 , pp. 174-181
    • Klein-Nulend, J.1    Roelofsen, J.2    Semeins, C.M.3    Bronckers, A.L.4    Burger, E.H.5
  • 41
    • 0029617377 scopus 로고
    • Pulsating fluid flow increases nitric oxide (NO) synthesis by osteocytes but not periosteal fibroblasts - correlation with prostaglandin upregulation
    • Klein-Nulend J., Semeins C.M., Ajubi N.E., Nijweide P.J., Burger E.H. Pulsating fluid flow increases nitric oxide (NO) synthesis by osteocytes but not periosteal fibroblasts - correlation with prostaglandin upregulation. Biochem Biophys Res Commun. 217:1995;640-648.
    • (1995) Biochem Biophys Res Commun , vol.217 , pp. 640-648
    • Klein-Nulend, J.1    Semeins, C.M.2    Ajubi, N.E.3    Nijweide, P.J.4    Burger, E.H.5
  • 42
    • 0030947454 scopus 로고    scopus 로고
    • Connexin46 is retained as monomers in a trans-Golgi compartment of osteoblastic cells
    • Koval M., Harley J.E., Hick E., Steinberg T.H. Connexin46 is retained as monomers in a trans-Golgi compartment of osteoblastic cells. J Cell Biol. 137:1997;847-857.
    • (1997) J Cell Biol , vol.137 , pp. 847-857
    • Koval, M.1    Harley, J.E.2    Hick, E.3    Steinberg, T.H.4
  • 44
    • 0009548732 scopus 로고    scopus 로고
    • Impaired intramembranous bone formation in connexin43 null mice
    • Lecanda F., Warlow P., Halstead L.R., Steinberg T.H., Civitelli R. Impaired intramembranous bone formation in connexin43 null mice. Bone. 23:(Suppl.):1998;S149.
    • (1998) Bone , vol.23 , Issue.SUPPL. , pp. 149
    • Lecanda, F.1    Warlow, P.2    Halstead, L.R.3    Steinberg, T.H.4    Civitelli, R.5
  • 46
    • 0032725056 scopus 로고    scopus 로고
    • Inhibiting gap junctional intercellular communication alters expression of differentiation markers in osteoblastic cells
    • Li Z., Zhou Z., Yellowley C.E., Donahue H.J. Inhibiting gap junctional intercellular communication alters expression of differentiation markers in osteoblastic cells. Bone. 25:1999;661-666.
    • (1999) Bone , vol.25 , pp. 661-666
    • Li, Z.1    Zhou, Z.2    Yellowley, C.E.3    Donahue, H.J.4
  • 47
    • 0029742875 scopus 로고    scopus 로고
    • The role of gap junction membrane channels in development [review]
    • Lo C.W. The role of gap junction membrane channels in development [review]. J Bioenerg Biomembr. 28:1996;379-385.
    • (1996) J Bioenerg Biomembr , vol.28 , pp. 379-385
    • Lo, C.W.1
  • 48
    • 0029810762 scopus 로고    scopus 로고
    • Intermittent compressive load stimulates osteogenesis and improves osteocyte viability in bones cultured "in vitro."
    • Lozupone E., Palumbo C., Favia A., Ferretti M., Palazzini S., Cantatore F.P. Intermittent compressive load stimulates osteogenesis and improves osteocyte viability in bones cultured "in vitro." Clin Rheumatol. 15:1996;563-572.
    • (1996) Clin Rheumatol , vol.15 , pp. 563-572
    • Lozupone, E.1    Palumbo, C.2    Favia, A.3    Ferretti, M.4    Palazzini, S.5    Cantatore, F.P.6
  • 49
    • 0017640572 scopus 로고
    • Gap junction structures. II. Analysis of the x-ray diffraction data
    • Makowski L., Caspar D.L., Phillips W.C., Goodenough D.A. Gap junction structures. II. Analysis of the x-ray diffraction data. J Cell Biol. 74:1977;629-645.
    • (1977) J Cell Biol , vol.74 , pp. 629-645
    • Makowski, L.1    Caspar, D.L.2    Phillips, W.C.3    Goodenough, D.A.4
  • 51
    • 0032547238 scopus 로고    scopus 로고
    • Proliferation and differentiation of human osteoblastic cells associated with differential activation of MAP kinases in response to epidermal growth factor, hypoxia, and mechanical stress in vitro
    • Matsuda N., Morita N., Matsuda K., Watanabe M. Proliferation and differentiation of human osteoblastic cells associated with differential activation of MAP kinases in response to epidermal growth factor, hypoxia, and mechanical stress in vitro. Biochem Biophys Res Commun. 249:1998;350-354.
    • (1998) Biochem Biophys Res Commun , vol.249 , pp. 350-354
    • Matsuda, N.1    Morita, N.2    Matsuda, K.3    Watanabe, M.4
  • 54
    • 0033011398 scopus 로고    scopus 로고
    • Antisense oligonucleotide blockade of connexin expression during embryonic bone formation: Evidence of functional compensation within a multigene family
    • Minkoff R., Bales E.S., Kerr C.A., Struss W.E. Antisense oligonucleotide blockade of connexin expression during embryonic bone formation Evidence of functional compensation within a multigene family . Devel Genet. 24:1999;43-56.
    • (1999) Devel Genet , vol.24 , pp. 43-56
    • Minkoff, R.1    Bales, E.S.2    Kerr, C.A.3    Struss, W.E.4
  • 55
    • 0027968667 scopus 로고
    • Gap junction proteins exhibit early and specific expression during intramembranous bone formation in the developing chick mandible
    • Minkoff R., Rundus V.R., Parker S.B., Hertzberg E.L., Laing J.G., Beyer E.C. Gap junction proteins exhibit early and specific expression during intramembranous bone formation in the developing chick mandible. Anat Embryol. 190:1994;231-241.
    • (1994) Anat Embryol , vol.190 , pp. 231-241
    • Minkoff, R.1    Rundus, V.R.2    Parker, S.B.3    Hertzberg, E.L.4    Laing, J.G.5    Beyer, E.C.6
  • 56
    • 0028212163 scopus 로고
    • Direct signaling from astrocytes to neurons in cultures of mammalian brain cells
    • Nedergaard M. Direct signaling from astrocytes to neurons in cultures of mammalian brain cells. Science. 263:1994;1768-1771.
    • (1994) Science , vol.263 , pp. 1768-1771
    • Nedergaard, M.1
  • 57
    • 0031023382 scopus 로고    scopus 로고
    • Fluid flow induces enhancement of the Egr-1 mRNA level in osteoblast-like cells: Involvement of tyrosine kinase and serum
    • Ogata T. Fluid flow induces enhancement of the Egr-1 mRNA level in osteoblast-like cells Involvement of tyrosine kinase and serum . J Cell Physiol. 170:1997;27-34.
    • (1997) J Cell Physiol , vol.170 , pp. 27-34
    • Ogata, T.1
  • 60
    • 0025630632 scopus 로고
    • Morphological study of intercellular junctions during osteocyte differentiation
    • Palumbo C., Palazzini S., Marotti G. Morphological study of intercellular junctions during osteocyte differentiation. Bone. 11:1990;401-406.
    • (1990) Bone , vol.11 , pp. 401-406
    • Palumbo, C.1    Palazzini, S.2    Marotti, G.3
  • 61
    • 0022531305 scopus 로고
    • Molecular cloning of cDNA for rat liver gap junction protein
    • Paul D.L. Molecular cloning of cDNA for rat liver gap junction protein. J Cell Biol. 103:1986;123-134.
    • (1986) J Cell Biol , vol.103 , pp. 123-134
    • Paul, D.L.1
  • 62
    • 0031724316 scopus 로고    scopus 로고
    • Regional differences in cell shape and gap junction expression in rat Achilles tendon: Relation to fibrocartilage differentiation
    • Ralphs J.R., Benjamin M., Waggett A.D., Russell D.C., Messner K., Gao J. Regional differences in cell shape and gap junction expression in rat Achilles tendon Relation to fibrocartilage differentiation . J Anat. 193:1998;215-222.
    • (1998) J Anat , vol.193 , pp. 215-222
    • Ralphs, J.R.1    Benjamin, M.2    Waggett, A.D.3    Russell, D.C.4    Messner, K.5    Gao, J.6
  • 63
    • 0025359865 scopus 로고
    • Fluid shear stress as a mediator of osteoblast cyclic adenosine monophosphate production
    • Reich K.M., Gay C.V., Frangos J.A. Fluid shear stress as a mediator of osteoblast cyclic adenosine monophosphate production. J Cell Physiol. 143:1990;100-104.
    • (1990) J Cell Physiol , vol.143 , pp. 100-104
    • Reich, K.M.1    Gay, C.V.2    Frangos, J.A.3
  • 64
    • 0031046164 scopus 로고    scopus 로고
    • Activation of G proteins mediates flow-induced prostaglandin E2 production in osteoblasts
    • Reich K.M., McAllister T.N., Gudi S., Frangos J.A. Activation of G proteins mediates flow-induced prostaglandin E2 production in osteoblasts. Endocrinology. 138:1997;1014-1018.
    • (1997) Endocrinology , vol.138 , pp. 1014-1018
    • Reich, K.M.1    McAllister, T.N.2    Gudi, S.3    Frangos, J.A.4
  • 65
    • 0016772025 scopus 로고
    • Cyclic AMP and cyclic GMP: Mediators of the mechanical effects on bone remodeling
    • Rodan G.A., Bourret L.A., Harvey A., Mensi T. Cyclic AMP and cyclic GMP Mediators of the mechanical effects on bone remodeling . Science. 189:1975;467-469.
    • (1975) Science , vol.189 , pp. 467-469
    • Rodan, G.A.1    Bourret, L.A.2    Harvey, A.3    Mensi, T.4
  • 66
    • 0024565202 scopus 로고
    • Prevention of osteoporosis by pulsed electromagnetic fields
    • Rubin C.T., McLeod K.J., Lanyon L.E. Prevention of osteoporosis by pulsed electromagnetic fields. J Bone Jt Surg [Am]. 71:1989;411-417.
    • (1989) J Bone Jt Surg [Am] , vol.71 , pp. 411-417
    • Rubin, C.T.1    McLeod, K.J.2    Lanyon, L.E.3
  • 67
    • 0029738523 scopus 로고    scopus 로고
    • Transforming growth factor-beta, osteogenin, and bone morphogenetic protein-2 inhibit intercellular communication and alter cell proliferation in MC3T3-E1 cells
    • Rudkin G.H., Yamaguchi D.T., Ishida K., Peterson W.J., Bahadosingh F., Thye D., Miller T.A. Transforming growth factor-beta, osteogenin, and bone morphogenetic protein-2 inhibit intercellular communication and alter cell proliferation in MC3T3-E1 cells. J Cell Physiol. 168:1996;433-441.
    • (1996) J Cell Physiol , vol.168 , pp. 433-441
    • Rudkin, G.H.1    Yamaguchi, D.T.2    Ishida, K.3    Peterson, W.J.4    Bahadosingh, F.5    Thye, D.6    Miller, T.A.7
  • 68
    • 0031792839 scopus 로고    scopus 로고
    • Fluid shear stress increases transforming growth factor beta 1 expression in human osteoblast-like cells: Modulation by cation channel blockades
    • Sakai K., Mohtai M., Iwamoto Y. Fluid shear stress increases transforming growth factor beta 1 expression in human osteoblast-like cells Modulation by cation channel blockades . Calcif Tissue Int. 63:1998;515-520.
    • (1998) Calcif Tissue Int , vol.63 , pp. 515-520
    • Sakai, K.1    Mohtai, M.2    Iwamoto, Y.3
  • 69
    • 0026746159 scopus 로고
    • Hormonal regulation of intercellular communication: Parathyroid hormone increases connexin 43 gene expression and gap-junctional communication in osteoblastic cells
    • Schiller P.C., Mehta P.P., Roos B.A., Howard G.A. Hormonal regulation of intercellular communication Parathyroid hormone increases connexin 43 gene expression and gap-junctional communication in osteoblastic cells . Mol Endocrinol. 6:1992;1433-1440.
    • (1992) Mol Endocrinol , vol.6 , pp. 1433-1440
    • Schiller, P.C.1    Mehta, P.P.2    Roos, B.A.3    Howard, G.A.4
  • 70
    • 0030833934 scopus 로고    scopus 로고
    • Parathyroid hormone up-regulation of connexin 43 gene expression in osteoblasts depends on cell phenotype
    • Schiller P.C., Roos B.A., Howard G.A. Parathyroid hormone up-regulation of connexin 43 gene expression in osteoblasts depends on cell phenotype. J Bone Miner Res. 12:1997;2005-2013.
    • (1997) J Bone Miner Res , vol.12 , pp. 2005-2013
    • Schiller, P.C.1    Roos, B.A.2    Howard, G.A.3
  • 71
    • 0032217162 scopus 로고    scopus 로고
    • 3, 17β-estradiol, vasoactive intestinal peptide, and glutamate on electric coupling between rat osteoblast-like cells in vitro
    • 3, 17β-estradiol, vasoactive intestinal peptide, and glutamate on electric coupling between rat osteoblast-like cells in vitro. Bone. 23:1998;521-526.
    • (1998) Bone , vol.23 , pp. 521-526
    • Schirrmacher, K.1    Bingmann, D.2
  • 74
    • 0343505710 scopus 로고    scopus 로고
    • Mechanical strain versus wall shear stress as the stimulus to bone cells in mechanical loading
    • Smalt R., Mitchell F.T., Howard R.L., Chambers T.J. Mechanical strain versus wall shear stress as the stimulus to bone cells in mechanical loading. J Bone Miner Res. 11:(Suppl.):1996;S265.
    • (1996) J Bone Miner Res , vol.11 , Issue.SUPPL. , pp. 265
    • Smalt, R.1    Mitchell, F.T.2    Howard, R.L.3    Chambers, T.J.4
  • 75
    • 0029614782 scopus 로고
    • Cellular deformation reversibly depresses RT-PCR detectable levels of bone-related mRNA
    • Stanford C.M., Stevens J.W., Brand R.A. Cellular deformation reversibly depresses RT-PCR detectable levels of bone-related mRNA. J Biomech. 28:1995;1419-1421.
    • (1995) J Biomech , vol.28 , pp. 1419-1421
    • Stanford, C.M.1    Stevens, J.W.2    Brand, R.A.3
  • 77
    • 0031184124 scopus 로고    scopus 로고
    • Expression of connexin 43 in rat mandibular bone and PDL cells during experimental tooth movement
    • Su M., Borke J.L., Donahue H.J., Li Z., Warshawsky N.M., Russell C.M. Expression of connexin 43 in rat mandibular bone and PDL cells during experimental tooth movement. J Dent Res. 76:1997;1357-1366.
    • (1997) J Dent Res , vol.76 , pp. 1357-1366
    • Su, M.1    Borke, J.L.2    Donahue, H.J.3    Li, Z.4    Warshawsky, N.M.5    Russell, C.M.6
  • 78
    • 0030068234 scopus 로고    scopus 로고
    • Bone marrow stromal cells are load responsive in vitro
    • Thomas G.P., el Haj A.J. Bone marrow stromal cells are load responsive in vitro. Calcif Tissue Int. 58:1996;101-108.
    • (1996) Calcif Tissue Int , vol.58 , pp. 101-108
    • Thomas, G.P.1    El Haj, A.J.2
  • 79
    • 0030954452 scopus 로고    scopus 로고
    • Vibrational force alters mRNA expression in osteoblasts
    • Tjandrawinata R.R., Vincent V.L., Hughes-Fulford M. Vibrational force alters mRNA expression in osteoblasts. FASEB J. 11:1997;493-497.
    • (1997) FASEB J , vol.11 , pp. 493-497
    • Tjandrawinata, R.R.1    Vincent, V.L.2    Hughes-Fulford, M.3
  • 80
    • 0030827291 scopus 로고    scopus 로고
    • Signal transduction of mechanical stimuli is dependent on microfilament integrity: Identification of osteopontin as a mechanically induced gene in osteoblasts
    • Toma C.D., Ashkar S., Gray M.L., Schaffer J.L., Gerstenfeld L.C. Signal transduction of mechanical stimuli is dependent on microfilament integrity Identification of osteopontin as a mechanically induced gene in osteoblasts . J Bone Miner Res. 12:1997;1626-1636.
    • (1997) J Bone Miner Res , vol.12 , pp. 1626-1636
    • Toma, C.D.1    Ashkar, S.2    Gray, M.L.3    Schaffer, J.L.4    Gerstenfeld, L.C.5
  • 81
    • 0028024121 scopus 로고
    • Mechanotransduction in bone: Do bone cells act as sensors of fluid flow?
    • Turner C.H., Forwood M.R., Otter M.W. Mechanotransduction in bone Do bone cells act as sensors of fluid flow? FASEB J. 8:1994;875-878.
    • (1994) FASEB J , vol.8 , pp. 875-878
    • Turner, C.H.1    Forwood, M.R.2    Otter, M.W.3
  • 82
    • 0343505709 scopus 로고    scopus 로고
    • Osteoblastic cell networks with deficient gap junctional coupling: Evidence for differential effects of magnetic and electric field exposure
    • To be published
    • Vander Molen, M. A., Donahue, H. J., Rubin, C. T., and McLeod, K. J. Osteoblastic cell networks with deficient gap junctional coupling: Evidence for differential effects of magnetic and electric field exposure. Bone. To be published.
    • Bone
    • Vander Molen, M.A.1    Donahue, H.J.2    Rubin, C.T.3    McLeod, K.J.4
  • 83
    • 15844394777 scopus 로고    scopus 로고
    • Gap junctional intercellular communication contributes to hormonal responsiveness in osteoblastic networks
    • Vander Molen M.A., Rubin C.T., McLeod K.J., McCauley L.K., Donahue H.J. Gap junctional intercellular communication contributes to hormonal responsiveness in osteoblastic networks. J Biol Chem. 271:1996;12165-12171.
    • (1996) J Biol Chem , vol.271 , pp. 12165-12171
    • Vander Molen, M.A.1    Rubin, C.T.2    McLeod, K.J.3    McCauley, L.K.4    Donahue, H.J.5
  • 84
    • 0028386524 scopus 로고
    • A model for the excitation of osteocytes by mechanical loading induced bone fluid shear stresses
    • Weinbaum S., Cowin S.C., Zeng Y.A. A model for the excitation of osteocytes by mechanical loading induced bone fluid shear stresses. J Biomech. 27:1994;339-360.
    • (1994) J Biomech , vol.27 , pp. 339-360
    • Weinbaum, S.1    Cowin, S.C.2    Zeng, Y.A.3
  • 85
    • 0028858395 scopus 로고
    • Regulation of gap junction intercellular communication by pH in MC3T3-E1 osteoblastic cells
    • Yamaguchi D.T., Huang J.T., Ma D. Regulation of gap junction intercellular communication by pH in MC3T3-E1 osteoblastic cells. J Bone Miner Res. 10:1995;1891-1899.
    • (1995) J Bone Miner Res , vol.10 , pp. 1891-1899
    • Yamaguchi, D.T.1    Huang, J.T.2    Ma, D.3
  • 86
    • 0028321790 scopus 로고
    • Isolation and characterization of gap junctions in the osteoblastic MC3T3-E1 cell line
    • Yamaguchi D.T., Ma D., Lee A., Huang J., Gruber H.E. Isolation and characterization of gap junctions in the osteoblastic MC3T3-E1 cell line. J Bone Miner Res. 9:1994;791-803.
    • (1994) J Bone Miner Res , vol.9 , pp. 791-803
    • Yamaguchi, D.T.1    Ma, D.2    Lee, A.3    Huang, J.4    Gruber, H.E.5
  • 88
    • 0031317585 scopus 로고    scopus 로고
    • Biochemical analysis of the response in rat bone marrow cell cultures to mechanical stimulation
    • Yoshikawa T., Peel S.A., Gladstone J.R., Davies J.E. Biochemical analysis of the response in rat bone marrow cell cultures to mechanical stimulation. Biomed Mater Eng. 7:1997;369-377.
    • (1997) Biomed Mater Eng , vol.7 , pp. 369-377
    • Yoshikawa, T.1    Peel, S.A.2    Gladstone, J.R.3    Davies, J.E.4
  • 89
    • 0343069692 scopus 로고    scopus 로고
    • Physiological levels of substrate deformation are less stimulatory to bone cells than are physiological levels of fluid flow
    • In press
    • You, J., Yellowley, C. E., Donahue, H. J., Zhang, Y., Chen, Q., and Jacobs, C. R. Physiological levels of substrate deformation are less stimulatory to bone cells than are physiological levels of fluid flow. J Biomech Eng. In press.
    • J Biomech Eng.
    • You, J.1    Yellowley, C.E.2    Donahue, H.J.3    Zhang, Y.4    Chen, Q.5    Jacobs, C.R.6
  • 90
    • 0030968233 scopus 로고    scopus 로고
    • Early responses to dynamic strain change and prostaglandins in bone-derived cells in culture
    • Zaman G., Suswillo R.F., Cheng M.Z., Tavares I.A., Lanyon L.E. Early responses to dynamic strain change and prostaglandins in bone-derived cells in culture. J Bone Miner Res. 12:1997;769-777.
    • (1997) J Bone Miner Res , vol.12 , pp. 769-777
    • Zaman, G.1    Suswillo, R.F.2    Cheng, M.Z.3    Tavares, I.A.4    Lanyon, L.E.5
  • 91
    • 0032429339 scopus 로고    scopus 로고
    • Estimates of the peak pressures in bone pore water
    • Zhang D., Weinbaum S., Cowin S.C. Estimates of the peak pressures in bone pore water. J Biomech Eng. 120:1998;697-703.
    • (1998) J Biomech Eng , vol.120 , pp. 697-703
    • Zhang, D.1    Weinbaum, S.2    Cowin, S.C.3
  • 92
    • 0024787405 scopus 로고
    • Sequence and tissue distribution of a second protein of hepatic gap junctions, Cx26, as deduced from its cDNA
    • Zhang J.T., Nicholson B.J. Sequence and tissue distribution of a second protein of hepatic gap junctions, Cx26, as deduced from its cDNA. J Cell Biol. 109:1989;3391-3401.
    • (1989) J Cell Biol , vol.109 , pp. 3391-3401
    • Zhang, J.T.1    Nicholson, B.J.2
  • 93
    • 0031917705 scopus 로고    scopus 로고
    • Cyclic stretch enhances gap junctional communication between osteoblastic cells
    • Ziambaras K., Lecanda F., Steinberg T.H., Civitelli R. Cyclic stretch enhances gap junctional communication between osteoblastic cells. J Bone Miner Res. 13:1998;218-228.
    • (1998) J Bone Miner Res , vol.13 , pp. 218-228
    • Ziambaras, K.1    Lecanda, F.2    Steinberg, T.H.3    Civitelli, R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.