Expression of functional gap junctions in cultured pulmonary alveolar epithelial cells

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 272, Issue 6 16-6, 1997, Pages

  Lee, Yu Chen ^a   Yellowley, Clare E ^a   Li, Zhongyong ^a   Donahue, Henry J ^a   Rannels, D Eugene ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

Cell cell communication; Communicating junctions; Connexins; Gene expression; Type II cells

Indexed keywords

CONNEXIN 26; CONNEXIN 32; CONNEXIN 43; GAP JUNCTION PROTEIN; LUCIFER YELLOW; MESSENGER RNA; OCTANOL; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL JUNCTION; CONTROLLED STUDY; LUNG ALVEOLUS CELL TYPE 2; LUNG ALVEOLUS EPITHELIUM; LUNG ALVEOLUS MACROPHAGE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0030740599     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.1997.272.6.l1105     Document Type: Article

References (35)

1. Barrio, L. C., T. Suchyna, T. Bargiello, L. X. Xu, R. S. Roginski, M. V. L. Bennett, and B. J. Nicholson. Voltage dependence of homo- and heterotypic Cx26 and Cx32 gap junctions expressed in Xenopus oocytes. Proc. Natl. Acad. Sci. USA 88: 8410-8414, 1991.
2. Bartels, H. The air-blood barrier in the human lung, a freeze-fracture study. Cell Tissue Res. 198: 269-285, 1979.
3. Bartels, H., H.-J. Oestern, and G. Voss-Wermbter. Communicating-occluding junction complexes in the alveolar epithelium. Am. Rev. Respir. Dis. 121: 1017-1024, 1980.
4. Beyer, E. C. Gap junctions. Int. Rev. Cytol. 137: 1-38, 1993.
5. Beyer, E. C., D. L. Paul, and D. Goodenough. Connexin 43: a protein from rat heart homologous to a gap junction protein from liver. J. Cell Biol. 105: 2621-2629, 1987.
6. Brissette, J. L., N. M. Kumar, N. B. Gilula, J. E. Hall, and G. P. Dotto. Switch in gap junction protein expression is associated with selective changes in junctional permeability during keratinocyte differentiation. Proc. Natl. Acad. Sci. USA 91: 6453-6457, 1994.
7. Chaudhuri, R., K. Sigler, E. Dupont, J. E. Trosko, A. M. Malkinson, and R. J. Ruch. Gap junctional intercellular communication in mouse lung epithelial cell lines: effects of cell transformation and tumor promoters. Cancer Lett. 71: 11-18, 1993.
8. Crouch, E. Pathobiology of pulmonary fibrosis. Am. J. Physiol. 259 (Lung Cell. Mol. Physiol. 3): L159-L184, 1990.
9. Donahue, H. J., K. J. McLeod, C. T. Rubin, J. Andersen, E. A. Grine, E. L. Hertzberg, and P. R. Brink. Cell-to-cell communication in osteoblastic networks: cell line-dependent hormonal regulation of gap junction function. J. Bone Miner. Res. 10: 881-889, 1995.
10. Elfgang, C., R. Eckert, H. Lichtenberg-Frate, A. Butterweek, O. Traub, R. A. Klein, D. F. Hulser, and K. Willecke. Specific permeability and selective formation of gap junction channels in connexin-transfected HeLa cells. J. Cell Biol. 129: 805-817, 1995.
11. Gina, S. Mixing of connexins in gap junction membrane channels. Proc. Natl. Acad. Sci. USA 92: 9210-9214, 1995.
12. Gordon, R. E., R. F. Heller, J. R. Del Valle, and R. F. Heller. Membrane perturbations and mediation of gap junction formation in response to taurine treatment in normal and injured alveolar epithelia. Exp. Lung Res. 15: 895-908, 1989.
13. Hennemann, H., H.-J. Schwarz, and K. Willecke. Characterization of gap junction genes expressed in F9 embryonic carcinoma cells: molecular cloning of mouse connexin 31 and 45 cDNAs. Eur. J. Cell Biol. 57: 51-58, 1992.
14. Hennemann, H., T. Suchnya, H. Lichtenberg-Frate, S. Jungbluth, E. Dahl, J. Schwartz, B. J. Nicholson, and K. Willecke. Molecular cloning and functional expression of mouse connexin 40, a second gap junction gene preferentially expressed in lung. J. Cell Biol. 117: 1299-1310, 1992.
15. Heussen, G. A. H., and G. M. Alink. Inhibition of gap-junctional intercellular communication by TPA and airborne particulate matter in primary cultures of rat alveolar type II cells. Carcinogenesis 13: 719-722, 1992.
16. Kadle, R., J. T. Zhang, and B. J. Nicholson. Tissue specific distribution of differently phophorylated forms of Cx43. Mol. Cell. Biol. 11: 363-369, 1991.
17. Kanter, H. L., J. E. Saffitz, and E. C. Beyer. Cardiac myocytes express multiple gap junction proteins. Circ. Res. 70: 438-444, 1992.
18. Kumar, N. M., and N. B. Gilula. The gap junction communication channel. Cell 84: 381-388, 1996.
19. Lee, Y.-C., and D. E. Rannels. Alveolar macrophages modulate the epithelial cell response to coal dust in vitro. Am. J. Physiol. 270 (Lung Cell. Mol. Physiol. 14): L123-L132, 1996.
20. Levine, R. A., M. Serdy, L. Guo, and D. Holzschu. Elongation factor Tu as a control gene for mRNA analysis of lung development and other differentiation and growth regulated systems. Nucl. Acids Res. 21: 4426, 1993.
21. Loch-Caruso, R., and J. E. Trosko. Inhibited intercellular communication as a mechanistic link between tetratogenesis and carcinogenesis. CRC Crit. Rev. Toxicol. 16: 157-183, 1986.
22. Matesic, D. F., H. L. Rupp, W. J. Bonney, R. J. Ruch, and J. E. Trosko. Changes in gap-junction permeability, phosphorylation, and number mediated by phorbol ester and non-phorbol ester tumor promoters in rat liver epithelial cells. Mol. Carcinog. 10: 226-236, 1994.
23. Matthay, M. A., H. G. Folkesson, and A. S. Verkman. Salt and water transport across alveolar and distal airway epithelia in the adult lung. Am. J. Physiol. 270 (Lung Cell. Mol. Physiol. 14): L487-L503, 1996.
24. Murray, S. A., and W. H. Fletcher. Hormone-induced intercellular signal transfer dissociates cyclic AMP-dependent protein kinase. J. Cell Biol. 98: 1710-1719, 1984.
25. Paul, D. L. New functions for gap junctions. Curr. Opin. Cell Biol. 7: 665-672, 1995.
26. Paul, D. L. Molecular cloning of cDNA for rat liver gap junction protein. J. Cell Biol. 103: 123-134, 1986.
27. Rannels, D. E., B. Stockstill, R. R. Mercer, and J. D. Crapo. Cellular changes in the lungs of adrenalectomized animals following left pneumonectomy. Am. J. Respir. Cell Mol. Biol. 5: 351-362, 1991.
28. Rannels, S. R., and D. E. Rannels. Isolation and culture of type II pulmonary epithelial cells. In: Cell Biology: A Laboratory Handbook, edited by J. E. Celis. Orlando, FL: Academic, 1994, p. 116-123.
29. Schneeberger, E. E. Segmental differentiation of endothelial intercellular junctions in intra-acinar arteries and veins of the rat lung. Circ. Res. 49: 1102-1111, 1981.
30. Spray, D. C., and M. V. L. Bennett. Physioloy and pharmacology of gap junctions. Annu. Rev. Physiol. 47: 281-303, 1985.
31. Uhal, B. D., and D. E. Rannels. DNA distribution analysis of type II pneumocytes by laser flow cytometry: technical considerations. Am. J. Physiol. 261 (Lung Cell. Mol. Physiol. 5): L296-L306, 1991.
32. Vander Molen, M. A., C. T. Rubin, K. J. McLeod, L. K. McCauley, and H. J. Donahue. Gap junctional intercellular communication contributes to hormonal responsiveness in osteoblastic networks. J. Biol. Chem. 271: 21265-12171, 1996.
33. Willecke, K., H. Hennemann, E. Dahl, S. Jungbluth, and R. Heynkes. The diversity of connexin genes encoding gap junctional proteins. Eur. J. Cell Biol. 56: 1-7, 1991.
34. Willecke, K., R. Heynkes, E. Dahl, R. Stutenkemper, H. Hennemann, S. Jungbluth, T. Suchya, and B. J. Nicholson. Mouse connexin 37: cloning and functional expression of a gap junction gene highly expressed in lung. J. Cell Biol. 114: 1049-1057, 1991.
35. Zhang, J.-T., and B. J. Nicholson. Sequence and tissue distribution of a second protein of hepatic gap junctions, Cx 26, as deduced from its cDNA. J. Cell Biol. 109: 3391-3401, 1989.