Significance of formaldehyde-induced DNA-protein crosslinks for mutagenesis

Environmental and Molecular Mutagenesis

Volumn 32, Issue 3, 1998, Pages 260-268

  Merk, Oliver ^a   Speit, Günter ^a  

^a UNIVERSITY HOSPITAL ULM   (Germany)

Author keywords

Comet assay; DNA protein crosslinks; Formaldehyde; HPRT test; Micronucleus test; SCE test

Indexed keywords

FORMALDEHYDE;

ANIMAL CELL; ARTICLE; CARCINOGENESIS; CONTROLLED STUDY; CROSS LINKING; GENE MUTATION; GENOTOXICITY; MUTAGENESIS; NONHUMAN; PROTEIN DNA INTERACTION;

ANIMALS; CELL LINE; CHROMOSOME ABERRATIONS; CRICETINAE; CRICETULUS; CROSS-LINKING REAGENTS; DNA; FORMALDEHYDE; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; MICRONUCLEI, CHROMOSOME-DEFECTIVE; PROTEINS; SISTER CHROMATID EXCHANGE; TIME FACTORS;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS; MAMMALIA; RODENTIA;

EID: 0031797733     PISSN: 08936692     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2280(1998)32:3<260::AID-EM9>3.0.CO;2-M     Document Type: Article

References (24)

1. Casanova M, Morgan KT, Steinhagen WH, Everitt JI, Popp JA, Heck Hd'A (1991): Covalent binding of inhaled formaldehyde to DNA in the respiratory tract of rhesus monkeys: Pharmacokinetics, rat-to-monkey interspecies scaling, and extrapolation to man. Fundam Appl Toxicol 17:409-428.
2. Casanova M, Morgan KT, Steinhagen WH, Everitt JI, Popp JA, Heck Hd'A (1994): DNA-protein cross-links and cell replication at specific sites in the nose of F344 rats exposed subchronically to formaldehyde. Fundam Appl Toxicol 23:525-536.
3. Conaway CC, Whysner J, Verna LK, Williams GM (1996): Formaldehyde mechanistic data and risk assessment: Endogenous protection from DNA adduct formation. Pharmacol Ther 71:29-55.
4. Conolly RB, Andersen ME (1993): An approach to mechanism-based cancer risk assessment for formaldehyde. Environ Health Perspect Suppl 101:169-176.
5. Costa M, Zhitkovich A (1997): DNA-protein cross-links produced by various chemicals in cultured human lymphoma cells. J Toxicol Environ Health 50:433-449.
6. Costa M, Zhitkovich A, Gargas M, Paustenbach D, Finley B, Kuykendall J, Billings R, Carlson TJ, Wetterhahn K, Xu J, Patierno S, Bogdanffy M (1996): Interlaboratory validation of a new assay for DNA-protein crosslinks. Mutat Res 369:13-21.
7. Craft TR, Bermudez E, Skopek TR (1987): Formaldehyde mutagenesis and formation of DNA-protein crosslinks in human lymphoblasts in vitro. Mutat Res 176:147-155.
8. Crosby RM, Richardson KK, Craft TR, Benforado KB, Liber HL, Skopek TR (1988): Molecular analysis of formaldehyde-induced mutations in human lymphoblasts and E. coli. Environ Mol Mutagen 12:155-166.
9. Goldmacher VS, Thilly WG (1983): Formaldehyde is mutagenic for cultured human cells. Mutat Res 116:417-422.
10. Grafström RC, Fornace A Jr, Harris CC (1984): Repair of DNA damage caused by formaldehyde in human cells. Cancer Res 44:4323-4327.
11. Grafström RC, Hsu IC, Harris CC (1993): Mutagenicity of formaldehyde in Chinese hamster lung fibroblasts: Synergy with ionizing radiation and N-nitroso-N-methylurea. Chem Biol Interact 86:41-49.
12. Graves RJ, Green T (1996): Mouse liver glutathione S-transferase mediated metabolism of methylene chloride to a mutagen in the CHO/HPRT assay. Mutat Res 367:143-150.
13. Graves RJ, Trueman P, Jones S, Green T (1996): DNA sequence analysis of methylene chloride-induced HPRT mutations in Chinese hamster ovary cells: Comparison with the mutation spectrum obtained for 1,2-dibromoethane and formaldehyde. Mutagenesis 11:229-233.
14. Helbig R, Gerland E, Speit G (1994): The molecular nature of mutations induced by adriamycin at the hprt locus of V79 cells. Mutagenesis 9:113-116.
15. IARC (1995): Monographs on the Evaluation of Carcinogenic Risks to Humans: Wood Dust and Formaldehyde. IARC 62, Lyon, France.
16. Ma TH, Harris MM (1988): Review of the genotoxicity of formaldehyde. Mutat Res 196:37-59.
17. Natarajan AT, Darroudi F, Bussman CJM, van Kesteren-van Leeuwen AC (1983): Evaluation of the mutagenicity of formaldehyde in mammalian cytogenetic assays in vivo and vitro. Mutat Res 122:355-360.
18. Olive PL, Banáth JP (1995): Sizing highly fragmented DNA in individual apoptotic cells using the comet assay and a DNA crosslinking agent. Exp Cell Res 221:19-26.
19. Pfuhler S, Wolf U (1996): Detection of DNA-crosslinking agents with the alkaline comet assay. Environ Mol Mutagen 27:196-201.
20. Recio L, Sisk S, Pluta L, Bermudez E, Gross EA, Chen Z, Morgan K, Walker C (1992): p53 Mutations in formaldehyde-induced nasal squamous cell carcinomas in rats. Cancer Res 52:6113-6116.
21. Speit G, Habermeier B, Heibig R (1994): Differences in the response to mutagens between two V79 sublines. Mutat Res 325:105-111.
22. Speit G, Haupter S, Hartmann A (1998): Evaluation of the genotoxic properties of paraquat in V79 Chinese hamster cells. Mutat Res 412:187-193.
23. Tucker JD, Auletta A, Cimino MC, Dearfield KL, Jacobson-Kram D, Tice RR, Carrano AV (1993): Sister-chromatid exchange: Second report of the Gene-Tox program. Mutat Res 297:101-180.
24. Zhitkovich A, Costa M (1992): A simple, sensitive assay to detect DNA-protein crosslinks in intact cells and in vivo. Carcinogenesis 13:1485-1489.