Benzophenone boronic acid photoaffinity labeling of subtilisin CMMs to probe altered specificity

Bioorganic and Medicinal Chemistry

Volumn 8, Issue 3, 2000, Pages 563-570

  Desantis, Grace ^a   Paech, Christian ^b   Jones, J Bryan ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b GENENCOR INTERNATIONAL INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZOPHENONE; BENZOPHENONE DERIVATIVE; BORONIC ACID BENZOPHENONE; ENZYME INHIBITOR; MUTANT PROTEIN; SERINE PROTEINASE; SUBTILISIN; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL MODIFICATION; CONTROLLED STUDY; COVALENT BOND; CROSS LINKING; EGGERTHELLA LENTA; ELECTRICITY; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME KINETICS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROPHOBICITY; MASS SPECTROMETRY; PHOTOAFFINITY LABELING; PHOTOLYSIS;

AMINO ACID SEQUENCE; BACILLUS; BACTERIAL PROTEINS; BENZOPHENONES; BINDING SITES; BINDING, COMPETITIVE; BORONIC ACIDS; CROSS-LINKING REAGENTS; GENETIC ENGINEERING; KINETICS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PHOTOLYSIS; PHOTOSENSITIZING AGENTS; PROTEIN ENGINEERING; SERINE ENDOPEPTIDASES; SERINE PROTEINASE INHIBITORS; SUBTILISIN; TIME FACTORS;

BACILLUS LENTUS;

EID: 0033995894     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(99)00320-X     Document Type: Article

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