Paternal contributions to the mammalian zygote: Fertilization after sperm-egg fusion

International Review of Cytology

Volumn 195, Issue , 2000, Pages 1-65

  Sulovsky, Peter ^a   Schatten, Gerald ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Centrosome; Embryo; Fertilization; Intracytoplasmic sperm injection; Oocyte; Perinuclear theca; Round spermatid injection; Sperm; Spermatid

Indexed keywords

GLUTATHIONE; MITOCHONDRIAL DNA; UBIQUITIN;

AXONEME; BIOGENESIS; CELL NUCLEUS MEMBRANE; CELL ORGANELLE; CENTRIOLE; CENTROSOME; CHROMATIN; CYTOPLASM; EMBRYO; EMBRYO DEVELOPMENT; FEMALE; FERTILIZATION; GAMETOGENESIS; GENOME; HAPLOIDY; HUMAN; INFERTILITY THERAPY; INHERITANCE; INTRACYTOPLASMIC SPERM INJECTION; MALE; MAMMAL; MICROTUBULE; MITOCHONDRION; MOTHER; NONHUMAN; OOCYTE; PATERNITY; PREIMPLANTATION EMBRYO; PRIORITY JOURNAL; PRONUCLEUS; REPRODUCTION; REVIEW; SPERM; SPERMATID; SPERMATOGENESIS; ZYGOTE;

NON-PROGRAMMATIC;

CELL MEMBRANE; CELL NUCLEUS; CENTROSOME; FEMALE; HUMANS; MALE; MITOCHONDRIA; SIGNAL TRANSDUCTION; SPERM-OVUM INTERACTIONS; SPERMATOZOA;

MAMMALIA; RODENTIA;

EID: 0033990338     PISSN: 00747696     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Review

References (372)

1. Agell, N, and Mezquita, C. (1988). Cellular content of ubiquitin and formation of ubiquitin conjugates during chicken spermatogenesis. Biocliein. J. 250, 883-889.
2. Ahmadi, A., and Ng. S.-C. (1997). Sperm head decondensation, pronuclear formation, cleavage and embryonic development following intracytoplasmic injection of mitochondria-damaged sperm in mammals. Zygote 5, 247-253.
3. Aitken, R. J., Gordon, E., Harkiss, D., Twigg, J. P., Milne, P., Jennings, Z., and Irvine, D. S. (1998). Relative impact of oxidative stres on the functional competence and genomic integrity of human spermatozoa. Biol. Reprod. 59, 1037-1046.
4. Aitken, R. J., West, K., and Buckingham, D. (1994). Leukocytic infilration into the human ejaculate and its association with semen quality, oxidative stress, and sperm function, J. Androl. 15, 343-352.
5. Alien, J. F. (1996). Separate sexes and the mitochondria! theory of ageing. J. Tlieor. Biol. 180, 135-140.
6. Almeida, E. A., Huovila, A. P., Sutherland, A. E., Stephens, L. E., Calarco, P. G., Shaw, L. M., Mercurio, A. M., Sonnenberg, A., Primakoff, P., and Myles, D. G. (1995). Mouse egg integrin alpha 6 beta 1 functions as a sperm receptor. Cell 81, 1095-1104.
7. Angelopoulos, T., Krey, L., McCullough, A., Adler, A., and Grifo, J. (1997). A simple and objective approach to identifying human round spermatids. Hum. Reprod. 12, 2208-2216.
8. Ankel-Simons, F., and Cummins, J. M. (1996). Misconceptions about mitochondria and mammalian fertilization: Implications for theories on human evolution. Proc. Natl. Acad. Sci. USA 93, 13859-13863.
9. Antinori, S., Versaci, C., Dani, G., Antinori, M., Pozza, D., and Selman, H. A. (1997). Fertilization with human testicular spermatids: Four successful pregnancies. Hum. Repord. 12, 286-291.
10. Asch, R., Simerly, C. S., Ord, T., Ord, V. A., and Schatten, G. (1995). The stages at which human fertilization arrests: Microtubule and chromosome configurations in inseminated oocytes which fail to complete fertilization and development in humans. Hum. Reprod. 10, 1897-1906.
11. Aslam, I, Robins, A., Dowell, K., and Fishel, S. (1998). Isolation, purification and assessment of viability of spermatogenic cells from testicular biopsies of azoospermic men. Hum. Reprod. 13, 639-645.
12. Austin, C. R. (1961). "The Mammalian Egg." Blackwell, Oxford.
13. Bacetti, B., Renieri, T., Rosati, F., Selmi, M. G., and Casanova, S. (1997). Further observations on the morphogenesis of the round-headed human spermatozoa. Andrologia 9, 255-264.
14. Barak, Y., Kogosowski, A., Goldman, S., Soffer, Y., Gonen, Y., and Tesarik, J. (1998). Pregnancy and birth after transfer of embryos that developed from single-nucleated zygotes obtained by injection of round spermatids into oocytes. Fertil. Steril. 70, 67-70.
15. Barnett, D. K., Kimura, J., and Bavister, B. D. (1996). Translocation of active mitochondria during hamster preimplantation embryo development studied by confocal laser scanning microscopy. Dev. Dyn. 205, 64-72.
16. Barros, C, Crosby, J. A., and Moreno, R. D. (1996). Early steps of sperm-egg interactions during mammalian fertilization. Cell Biol. Int. 20, 33-39.
17. Barth, A. D., and Oko, R. (1989). "Abnormal Morphology of Bovine Spermatozoa," Iowa State Univ. Press, Ames, IA.
18. Battaglia, D. E., Koehler, J. K., Klein, N. A., and Tucker, M. J. (1997). Failure of oocyte activation after intracytoplasmic sperm injection using round-headed sperm. Fertil. Steril. 68, 118-122.
19. Bedford, J. M. (1968). Ultrastructural changes in the sperm head during fertilization in rabbit. Am. J. Anat. 123, 329-358.
20. Bedford, J. M. (1979). Evolution of the sperm maturation and sperm storage functions of the epididymis. In "The Spermatozoon" (D. W. Fawcett and J. M. Bedford, eds.), pp. 7-21. Urban and Schwarzenberg, BaltimoreMunich.
21. Bedford, J. M. (1998). Mammalian fertilization misread? Sperm penetration of the eutherian zona pellucida is unlikely to be a lytic event. Biol. Reprod. 59, 1275-1287.
22. Bedford, J. M., and Calvin, H. I. (1974). Changes in S-S linked structures of sperm tail during epididymal maturation, with comparative observation in submammalian species. J. Exp. Zool. 187, 181-204.
23. Bedford, J. M., and Cooper, G. W. (1978). Membrane fusion events in fertilization of vertebrate eggs. In "Membrane Surface Reviews (Membrane Fusion)" (G. Poste and G. L. Nicolson, eds.), Vol. 5, pp. 65-125. North-Holland, Amsterdam.
24. Bellvé, A. R., Chandrika, R., and Barth, A. H. (1990). Temporal expression, polar distribution and transition of an epitope domain in the perinuclear theca during mouse spermatogenesis. J. Cell Sci. 96, 745-756.
25. Bellvé, A. R., Chandrika, R., Martinova, Y. S., and Barth, A. H. (1992). The perinuclear matrix as a structural element of the mouse sperm nucleus. Biol. Reprod. 47, 451-465.
26. Benoff, S. (1997). Carbohydrates and fertilization: An overview. Mol. Hum. Repord. 3, 599-637.
27. Bernabeu, R., Cremades, N., Takahashi, K., and Sousa, M. (1998). Successful pregnancy after spermatid injection. Hum. Reprod. 13, 1898-1900.
28. Berndtston, W. E., and Desjardins, C. (1974). The cycle of the seminiferous epithelium and spermatogenesis in the bovine testis. Am. J. Anat. 140, 167-179.
29. Birky, C. W., Jr. (1995). Uniparental inheritance of mitochondrial and chloroplast genes: Mechanisms and evolution. Proc. Nail. Acad. Sci. USA 92, 11331-11338.
30. Bleil, J. D., and Wassarman, P. M. (1983). Sperm-egg interactions in the mouse: Sequence of events and induction of the acrosome reaction by a zona pellucida glycoprotein. Dev. Biol. 95, 317-324.
31. Blobel, C. P., Wolfsberg, T. G., Turck, C. W., Myles, D. G., Primakoff, P., and White, J. M. (1992). A potential fusion peptide and an integrin ligand domain in a protein active in sperm-egg fusion. Nature 356, 248-252.
32. Boman, A. L., Delannoy, M. R., an Wilson, K. L. (1992). GTP hydrolysis is required for vesicle fusion during nuclear envelope assembly in vitro. J. Cell Biol. 116, 281-294.
33. Bonduelle, M., Aytoz, A., Van Assche, E., Devroey, P., Liebaers, I., and Van Steirteghem, A. (1998). Incidence of chromosomal aberrations in children born after assisted reproduction through intracytoplasmic sperm injection. Hum. Reprod. 13, 781-782.
34. Bonifacino, J. S., and Weissman, A. M. (1998). Ubiquitin and the control of protein fate in the secretory and endocytotic pathways. Annu. Rev. Cell. Dev. Biol. 14, 19-57.
35. Boore, J. L. (1997). Transmission of mitochondrial DNA-playing favorites? BioEssay 19, 751-753.
36. Bouckson-Castaing, V., Moudjou, M., Ferguson, D. J., Mucklow, S., Belkaid, Y., Milon, G., and Crocker, P. R. (1996). Molecular characterisation of ninein, a new coiled-coil protein of the centrosome. J. Cell Sci. 109, 179-190.
37. Bourgain, C, Nagy, Z. P., De Zutter, H., Van Ranst, H., Noguiera, D., and Van Steirteghem. A. C. (1998). Ultrastructure of gametes after intracytoplasmic sperm injection. Hum. Reprod. 13(Suppl. 1), 107-116.
38. Boveri, T. (1901). "Zellen-Studien: Über die nature der centrosomen." IV Fisher, Jena, Germany.
39. Bowen, R. H. (1992). On the idiosome, Golgi apparatus and acrosome in the male germ cell. Anal. Rec. 24, 158-180.
40. Breed, W., Simerly, C, Navara, C. S., Vanderberg, J., and Schatten, G. (1994). Distribution of microtubules in eggs and early embryos of the marsupial, Monodelphis domestica. Dev. Biol. 164, 230-240.
41. Brinster, R. L., and Avarbock, M. R. (1994). Germline transmission of donor haplotype following spermatogonial transplantation. Proc. Natl. Acad. Sci. USA 91, 11303-11307.
42. Bronson, R. A., and Fusi, F. (1990). Evidence that an Arg-Gly-Asp adhesion sequence plays a role in mammalian fertilization. Biol. Reprod. 43, 1019-1025.
43. Bucci, L. R., Brock, W. A., Johnson, T. S., and Meistrich, M. L. (1986). Isolation and biochemical studies of enriched populations of spermatogonia and early primary spermatocytes from rat testes. Biol. Repord. 34, 195-206.
44. Burke, B., and Gerace, L. (1986). A cell free system to study reassembly of the nuclear envelope at the end of mitosis. Cell 44, 639-652.
45. Burks, D. J., Carballada, R., Moore, H. D., and Saling, P. M. (1995). Interaction of a tyrosine kinase from human sperm with the zona pellucida at fertilization. Science 269, 83-86.
46. Calvin, H. I., and Bedford, J. M. (1971). Formation of disulfide bonds in the nucleus and accessory structures of mammalian spermatozoa during maturation in the epididymis. J. Reprod. Fend. Suppl. 13, 65-75.
47. Campbell, K. H., McWhir, J., Ritchie, W. A., and Wilmut, I. (1996). Sheep cloned by nuclear transfer from a cultured cell line. Nature 380, 64-66.
48. Carrera, A., Gerton, G. L., and Moss, S. B. (1994). The major fibrous sheath polypeptide of mouse sperm: Structural and functional similarities to the A-kinase anchoring protein. Dev. Biol. 165, 272-284.
49. Cataldo, L., Baig, K., Oko, R., Mastrangello, M.-.A, and Kleene, K. C. (1996). Developmental expression, intracellular localization, and selenium content of the cysteine-rich protein associated with the mitochondrial capsules of mouse sperm. Mol. Reprod. Dev. 45,320-331.
50. Catt, J., and O'Neill, C. (1995). Manipulation of sperm before intracytoplasmic sperm injection improves fertilization rates. Fertil. Steril. 64, 1210-1212.
51. Catt, J. W., and Rhodes, S. L. (1995). Comparative intracytoplasmic sperm injection (ICSI) in human and domestic species. Reprod. Fertil. Dev. 1, 161-166.
52. Catt, S. L., Catt, J. W., Gomez, M. C, Maxwell W. M., and Evans, G. (1996). Birth of a male lamb derived from an in vitro matured oocyte fertilised by intracytoplasmic injection of a single presumptive male spernu Vet. Rec. 139, 494-495.
53. Chau, V.,Tobias, J. W., Bachmair, A., Marriott, D., Ecker, D. J., Gonda, D. K., and Varshavsky, A. (1989). A multiubiquitin chain is confined to specific lysine in a targeted short-lived protein. Science 243, 1576-1583.
54. Cheng, A., Le, T., Palacios, M., Bookbinder, L. H., Wassarman, P. M., Suzuki, F., and Bleil, J. D. (1994). Sperm-egg recognition in the mouse: Characterization of sp56, a sperm protein having specific affinity for ZP3. J. Cell Biol. 125, 867-878.
55. Chian, R. C., Tan, S. L., and Sirard, M. A. (1999). Protein phosphorylation is essential for formation of male pronucleus in bovine oocytes. Mol. Reprod. Dev. 52, 43-49.
56. Ciechanover, A. (1994). The ubiquitin-proteasome proteolytic pathway. Cell 79, 13-21.
57. Ciechanover, A., Finley, D., and Varshavsky, A. (1984). Ubiquitin dependence of selective protein degradation demonstrated in the mammalian cell cycle mutants. Cell 37, 57-66.
58. Cho, C, O'Dell Bunch, D., Faure, J.-E., Goulding, E. H., Eddy, E. M., Primakoff, P., and Myles, D. G. (1998). Fertilization defects in sperm from mice lacking fertilin β. Science 281, 1857-1859.
59. Cho, C, Primakoff, P., White, J. M., and Myles, D. G. (1996). Chromosomal assignment of four testis-expressed mouse genes from a new family of transmembrane proteins (AD AMs) involved in cell-cell adhesion and fusion. Genomics 34, 413-417.
60. Cho, C, Turner, L., Primakoff, P., and Myles, D. G. (1997). Genomic organization of the mouse fertilin beta gene that encodes an ADAM family protein active in sperm-egg fusion. Dev. Genet. 20, 320-832.
61. Cibelli, J. B., Slice, S. L., Golueke, P. J., Kane, J. J., Jerry, J., Blackwell, C, Ponce de Leon, F. A., and Robl, J. M. (1998). Cloned transgenic calves produced from nonquiescent fetal fibroblasts. Science 280, 1256-1258.
62. Clermont, Y. (1969). Two classes of spermatogonial stem cells in the monkey (Cercopithecus aethiops). Am. J. Anat. 126, 57-72.
63. Clermont, Y. (1972). Kinetics of spermatogenesis in mammals: Seminiferous epithelium cycle and spermatogonial renewal. Physiol. Rev. 52,198-236.
64. Clouthier, D. E., Avarbock, M. R., Maika, S. D., Hammer, R. E., and Brinster, R. L. (1996). Rat spermatogenesis in mouse testis. Nature 381, 418-421.
65. Cohen, D. J., Munuce, M. J., and Cuasnicu, P. S. (1996). Mammalian sperm-egg fusion: The development of rat oolemma fusibility during oogenesis involves the appearance of binding sites for sperm protein "DE." Biol. Reprod. 55, 200-206.
66. Cohen, J., Scott, R., Schimel, T., Levron, J., and Wilandsen, S. (1997). Birth of infant after transfer of annucleate donor oocyte cytoplasm into recipient eggs. Lancet 350,186-187.
67. Collas, P., Courvalin, J.-G, and Poccia, D. (1996). Targeting of membranes to sea urchin sperm chromatin is mediated by a lamin B receptor-like integral membrane protein J. Cell Biol. 135, 1715-1725.
68. Colleu, D., Lescoat, D., Thomas, D., and Gouranton, J. (1997). Changes in protamine 1 distribution in human sperm nucleus during in vitro sperm-oocyte interaction: An immunoelectron microscopic study. Fertil. Steril. 67, 123-128.
69. Compton, D. A., and Cleveland, D. W. (1994). NuMA, a nuclear protein involved in mitosis and nuclear reformation. Cnrr. Opin. Cell Biol. 6, 343-346.
70. Coonrod, S. A., Herr, J. C, and Westhusin, M. E. (1996). Inhibition of bovine fertilization in vitro by antibodies to SP-10. J. Reprod. Fertil. 107, 287-297.
71. Cortopassi, G. A., Shibata, D., Soong, N. W., and Arnehim, N. (1992). A pattern of accumulation of a somatic deletion of mitochondrial DNA in aging human tissues. Proc. Natl. Acad. Sci. USA 89, 7370-7374.
72. Courtens, J. L., Courot, M., and Flechon, J. E. (1976). The perinuclear substance of boar, bull, ram and rabbit spermatozoa. J. Ultraslruct. Res. 57, 54-64.
73. Cross, S. M., Sanchez, C. A., Morgan, C. A., Schimke, M. K., Ramel, S., Idzerda, R. L., Raskind, W. H., and Reid, B. J. (1995). A p53-dependent mouse spindle checkpoint. Science 267,1353-1356.
74. Crozet, N. (1990). Behavior of sperm centriole during sheep fertilization. Eur. J. Cell Biol. 53, 326-332.
75. Cummins, J. (1998). Mitochondrial DNA in mammalian reproduction. Rev. Reprod. 3,172-182.
76. Cummins, J. M., Jequier, A. M., and Kan, R. (1994). Molecular biology of human male infertility-links with aging, mitochondrial genetics, and oxidative stress? Mol. Reprod. Dev. 37, 345-362.
77. Cummins, J. M., Wakayma, T., and Yanagimachi, R. (1997). Fate of microinjected sperm components in the mouse oocyte and embryo. Zygote 5, 301-308.
78. Cummins, J. M., Wakayma, T., and Yanagimachi, R. (1998). Fate of microinjected spermatid mitochondria in the mouse oocyte and embryo. Zygote 6, 213-222.
79. de Krester, D. M., and Kerr, J. B. (1994). The cytology of the testis. In "The Physiology of Reproduction" (E. Knobil and J. D. Neill, eds.), 2nd Ed. pp. 1177-1289. Raven Press, New York.
80. Dell'Aquila, M. E., Cho, Y. S., Minoia, P., Traîna, V., Lacalandra, G. M., and Maritato, F. (1997). Effects of follicular fluid supplementation of in-vitro maturation medium on the fertilization and development of equine oocytes after in-vitro fertilization or intracytoplasmic sperm injection. Hum. Reprod. 12, 2766-2772.
81. Doxsey, S. J., Stein, P., Evans, L., Calarco, P. D., and Kirschner, M. (1994). Pericentrin, a highly conserved centrosome protein involved in microtubule organization. Cell 76,639-650.
82. Dozortsev, D., Wakayama, T., Ermilov, A., and Yanagimachi, R. (1998). Intracytoplasmic sperm injection in the rat. Zygote 6, 143-147.
83. Ebert, K. M., Alcivar, A., Leim, H., Goggins, R., and Hecht, N. B. (1989). Mouse zygotes injected with mitochondria develop normally but the exogenous mitochondria are not detectable in the progeny. Mol. Reprod. Dev. 1, 156-163.
84. Ecklund, P. S., and Levine, L. (1975). Mouse sperm basic nuclear protein: Electrophoretic characterization and fate after fertilization. J. Cell Biol. 66, 251-262.
85. Escalier, D. (1990). Failure of differentiation of the nuclear-perinuclear skeletal complex in the round-headed human spermatozoa. Int. J. Dev. Biol. 34, 287-297.
86. Evans, J. P., Kopf, G. S., and Schultz, R. M., (1997a). Characterization of the binding of recombinant mouse sperm fertilin beta subunit to mouse eggs: Evidence for adhesive activity via an egg betal integrin-mediated interaction. Dev. Biol. 187, 79-93.
87. Evans, J. P., Schultz, R. M., and Kopf, G. S. (1995). Mouse sperm-egg plasma membrane interactions: Analysis of roles of egg integrins and the mouse sperm homologue of PH-30 (fertilin) beta. J. Cell Sci. 108, 3267-3278.
88. Evans, J. P., Schultz, R. M., and Kopf, G. S. (1997b). Characterization of the binding of recombinant mouse sperm fertilin alpha subunit to mouse eggs: Evidence for function as a cell adhesion molecule in sperm-egg binding. Dev. Biol. 187, 94-106.
89. Fawcett, D. W. (1975). The mammalian spermatozoon. Dev. Biol. 44, 394-436.
90. Fechter, J., Schöneberg, A., and Schatten, G. (1996). The excision and disassembly of sperm tail microtubules during sea urchin fertilization: Requirements for microtubule dynamics. Cell Motil. Cytoskel. 35, 281-288.
91. Felix, M., Antony, C, Write, M., and Maro, B. (1994). Centrosome assembly in vitro: Role of -y-tubulin recruitment in Xenopus sperm aster formation. J. Cell Biol. 124,19-31.
92. Fishel, S., Aslam, I., and Tesarik, J. (1996). Spermatid conception: A stage too early, or a time too soon? Hum. Reprod. 11, 1371-1375.
93. Fishel, S., Green, S., Bishop, M., Thornton, S., Hunter, A., Fleming, S., and al-Hassan, S. (1995). Pregnancy after intracytoplasmic injection of spermatid. Lancet 345, 1641-1642.
94. Flaherty, S. P., Payne, D., Swann, N., and Mathews, D. (1995). Aetiology of failed and abnormal fertilisation after intracytoplasmic sperm injection. Hum. Reprod. 10,2623-2629.
95. Florman, H. M., and Wassarman, P. M. (1985). O-linked oligosaccharides of mouse egg ZP3 account for its sperm receptor activity. Cell 41, 313-24.
96. Fouquet, J. P., Kann, M. L., and Melki, R. (1998). γ-tubulin during the differentiation of spermatozoa in various mammals and man. Mol. Hum. Reprod. 4, 1122-1129.
97. Frank, S. A., and Hurst, L. D. (1996) Mitochondria and male disease. Nature 383, 224.
98. Freemerman, A. J., Wright, R. M., Flickinger, C. J., and Herr, J. C. (1994). Tissue specificity of the acrosomal protein SP-10: A contraceptive vaccine candidate molecule. Biol. Reprod. 50, 615-621.
99. Fukasawa, K., Choi, T., Kuriyama, R., Rulong, S., and Vande Woude, G. F. (1996). Abnormal centrosome amplification in the absence of p53. Science 271, 1744-1747.
100. Fulka Jr., J., Horska, M., Moor, R. M., Fulka, J., and Kanka, J. (1996). Oocyte-specific modulation of female pronuclear development in mice. Dev. Biol. 178, 1-12.
101. Fusi, F. M, Bernocchi, N., Ferrari, A., and Bronson, R. A. (1996). Is vitronectin the velcro that binds the gametes together? Mol. Hum. Reprod. 2, 859-866.
102. Fusi, F. M., Vignali, M., Busacca, M., and Bronson, R. A. (1992). Evidence for the presence of an integrin cell adhesion receptor on the oolemma of unfertilized human oocytes. Mol. Reprod. Dev. 3, 215-222.
103. Gabel, C. A., Eddy, E. M., and Shapiro, B. M. (1979). After fertilization, sperm surface components remain as a patch in sea urchin and mouse embryos. Cell 18, 207-215.
104. Giles, R. E., Blanc, H., Cann, H. M., and Wallace, D. C. (1980). Maternal inheritance of human mitochondrial DNA. Proc. Nail. Acad. Sci. USA 77, 6715-6719.
105. Gledhill, B. L., Evenson, D. P. and Pinkel, D. (1990) Flow cytometry and sorting of sperm and male germ cells. In "Flow Cytometry and Sorting" (M. Melamed, T. Lindmo, and M. Mendelsohn, eds.), pp. 531-551. Willey-Liss, New York.
106. Glotzer, M., Murray, A. W., and Kirschner, M. W. (1991). Cyclin is degraded by the ubiquitin pathway Nature 349, 132-138.
107. Goldstein, G., Scheid, M., Hammerling, U., Schlesinger, D. H., Niall, H. D., and Boyse, E. A. (1975). Isolation of a polypeptide that has lymphocyte-differentiating properties and is probably represented universally in living cells. Proc. Natl. Acad. Sci. USA 72, 11-15.
108. Gong, X., Dubois, D. H., Miller, D. J., and Shur, B. D. (1995). Activation of a G protein complex by aggregation of beta-1, 4-galactosyltransferase on the surface of sperm. Science 269, 1718-1721.
109. Goto, K., Kinoshita, A., Takuma, Y., and Ogawa, K. (1990). Fertilisation of bovine oocytes by the injection of immobilised, killed spermatozoa. Vet. Rec. 127, 517-520.
110. Gould, R. R., and Borisy, G. G. (1977). The pericentriolar material in Chinese hamster ovary cells nucleates microtubule formation. J. Cell Biol. 73, 601-615.
111. Grabske, R. J., Lake, S., Gledhill, B. L., and Meistrich, M. L. (1975). Centrifugal elution: Separation of the spermatogenic cells on the basis of sedimentation velocity. J. Cell Physiol. 86, 177-189.
112. Gresson, R. A. R. (1940). Presence of the sperm middle-piece in the fertilized egg of the mouse (Mus miisculus). Nature 145, 425.
113. Griffith, O. W., and Meister, A. (1979). Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoximine). J. Biol. Chem. 254,7558-7560.
114. Grondahl, C, Hansen, T. H., Hossaini, A., Heinze, L, Grève, T., and Hyttel, P. (1997). Intracytoplasmic sperm injection of in vitro-matured equine oocytes. Biol. Reprod. 57,1495-1501.
115. Gundersen, G. G., Medill, L., and Shapiro, B. M. (1986). Sperm surface proteins are incorporated into egg membrane and cytoplasm after fertilization. Dev. Biol. 113, 207-217.
116. Gupta, S. K., Alves, K., Palladino, L. O., Mark, G. E., and Hollis, G. F. (1996). Molecular cloning of the human fertilin beta subunit. Biochem. Biophys. Res. Commun. 224,318-326.
117. Gyllensten, U., Wharton, D., Josefsson, A., and Wilson, A. C. (1991). Paternal inheritance of mitochondrial DNA in mice. Nature 352, 255-257.
118. Hardy, C. M., and Holland, M. K. (1996). Cloning and expression of recombinant rabbit fertilin. Mot. Reprod. Dev. 45, 107-116.
119. Hattori, K., Tanaka, M., Sugiyama, S., Obayashi, T., Ito, T., Satake, T., Hanaki, Y., Asai, J., Nagano, M., and Ozawa, T. (1991). Age-dependent increase in deleted mitochondrial DNA in the human heart: Possible contributory factor to presbycardia. Am. Heart J. 121,1735-1742.
120. Herrada, G., and Wolgemuth D. J. (1997). The mouse transcription factor Stat4 is expressed in haploid male germ cells and is present in the perinuclear theca of spermatozoa. J. Cell Sci. 110, 1543-1553.
121. Hertig, A. T., and Adams, E. (1967). Studies on the human oocyte and its follicle: Ultrastructural and cytochemical observations on the primordial follicle. J. Cell Biol. 34, 647-675.
122. Hess, H., Heid, H., and Franke, W. W. (1993). Molecular characterization of mammalian cylicin, a basic protein of the sperm head cytoskeleton. J. Cell Biol. 122, 1043-1052.
123. Hewitson, L., Dominko, T., Takahashi, D., Simerly, C, Santos, J., Sutovsky, P., Jacobs, D., Monteih, D., Fanton, J., Neuringer, M., Battaglia, D., and Schatten, G. (1999). Births of ICSI monkeys reveal checkpoints unique to the first cell cycle of fertilization. Nature Med. 5, 431-433.
124. Hewitson, L. C, Haavisto, A., Simerly, C, Jones, J., and Schatten, G. (1997). Microtubule organization and chromatin configurations in hamster oocytes during fertilization and parthenogenetic activation, and after insemination with human sperm. Biol. Reprod. 57, 967-975.
125. Hewitson, L. C., Simerly, C. R., Tengowski, M. W., Sutovsky, P., Navara, C. S., Haavisto, A. J., and Schatten, G. (1996). Microtubule and DNA configurations during rhesus intracytoplasmic sperm injection: Successes and failures. Biol. Reprod. 55, 271-280.
126. Hewitson, L., Takahashi, D., Dominko, T., Simerly, C, and Schatten, G. (1998). Fertilization and embryo development to blastocyst after intracytoplasmic sperm injection in the rhesus monkey. Hum. Reprod. 13, 3449-3455.
127. Hiraoka, J., and Hirao, Y. (1988). Fate of sperm tail components after incorporation into the hamster egg. Gamete Res. 19, 369-380.
128. Holstein, A. F., Schirren, C., and Schirren, C. G. (1973a). Human spermatids and spermatozoa lacking acrosomes. J. Reprod. Fertil. 35, 489-491.
129. Holstein, A. F., Schirren, C. G., Schirren, C., and Mauss, J. (1973b). Round headed spermatozoa: A cause of male infertility. Dtsch. Med. Wochenschr. 98, 61-62.
130. Holy, J., Wessel, G., Berg, L., Gregg, R. G., and Schatten, G. (1995). Molecular characterization and expression patterns of a B-type nuclear lamin during sea urchin embryogenesis. Dev. Biol. 168, 464-478.
131. Hooft van Huijsduijnen, R. (1998). ADAM 20 and 21; two novel human testis-specific membrane metalloproteases with similarity to fertilin-alpha. Gene 206, 273-282.
132. Hurst, L. D. (1992). Intragenomic conflict as an evolutionary force. Phil. Trans. Royal Soc. Land. Ser. B Bio. Sci. 248, 135-140.
133. Hurst, L. D., Allan, A., and Bengtsson, B. O. (1996). Genetic conflicts. Quart. Rev. Biol. 71, 317-364.
134. Hutchinson, C. A., Newbold, J. E., and Potter, S. S. (1974). Maternal inheritance of mammalian mitochondrial DNA. Nature 251, 536-538.
135. In't Veld, P., Brandenburg, H., Verhoeff, A., Dhont, M., and Los, F. (1995). Sex chromosomal abnormalities and intracytoplasmic sperm injection. Lancet 773, 346.
136. Iritani, A. and Hoshi, K. (1989). Microfertilization by various methods in mammalian species. In "Development of Preimplantation Embryos in Their Environment" (K. Yoshinaga and T. Mori, eds.), pp. 145-149. A. R. Liss, New York.
137. 2+ release. Dev. Biol. 177, 558-567.
138. Jaffe, L. F. (1980). Calcium explosions as triggers of development. Ann. N.Y. Acad. Sci. 339, 86-101.
139. Jentsch, S. (1992). The ubiquitin-conjugation system. Anna. Rev. Genet. 26, 179-207.
140. Jentsch, S., and Schlenker, S. (1995). Selective protein degradation: A journey's end within the proteasome. Cell 82, 881-884.
141. Jenuth, J. P., Peterson, A. C, and Shoubridge, E. A. (1997). Tissue-specific selection for different mtDNA genotypes in heteroplasmic mice. Nature Genet. 16, 93-95.
142. Ji, Y. Z., Wolf, J. P., Jouannet, P., and Bomsel, M. (1998). Human gamete fusion can bypass beta-1 integrin requirement. Hum. Reprod. 13, 682-689.
143. 2+ and fluorescent markers between the sperm and egg after fusion in the mouse. Development 125,4627-4635.
144. 2+ release in activated and aging mouse oocytes. Dev. Biol. 178, 229-237.
145. Jones, R. (1991). Interaction of zona pellucida glycoproteins, sulphated carbohydrates and synthetic polymers with proacrosin, the putative egg-binding protein from mammalian spermatozoa. Development 111, 1155-1163.
146. Joshi, H. C. (1993). y-tubulin: The hub of cellular microtubule assemblies. BioEssays 15, 637-643.
147. Joswig, G., Petzelt, C., and Werner, D. (1991). Murine cDNAs coding for the centrosomal antigen centrosomin A. J. Cell Sci. 98, 37-43.
148. Kalnins, V. I., and Rogers, K. A. (1992). The centrosome in stationary and migrating endothelial cells. In "The Centrosome" (V. I. Kalnins, éd.), pp. 287-312. Academic Press, New York.
149. Kalab, P., Visconti, P., Leclerc, P., and Kopf, G. S. (1994). p95, the major phosphotyrosinecontaining protein in mouse spermatozoa, is a hexokinase with unique properties. J. Biol. Chem. 269, 3810-3817.
150. Kaneda, H., Hayashi, J.-L, Takahama, S., Taya, C., Fischer-Lindahl., K., and Yonekawa, H. (1995). Elimination of paternal mitochondrial DNA in intraspecific crosses during early mouse embryogenesis. Proc. Natl. Acad. Sci. USA 92, 4542-4546.
151. Kanka, J., Fulka, J., Jr., Fulka, J., and Petr, J. (1991). Nuclear transplantation in bovine embryo: Fine structrual and autoradiographic studies. Mol. Reprod. Dev. 29, 110-116.
152. Kao, S.-H., Chao, H.-T., and Wei, Y.-H. (1995). Mitochondrial deoxyribonucleic acid 4977-bp deletion is associated with diminished fertility and motility of human sperm,. Biol. Reprod. 52, 729-736.
153. Kao, S.-H., Chao, H.-T., and Wei, Y.-H. (1998). Multiple deletions of mitochondrial DNA are associated with the decline of motility and fertility of human spermatozoa. Mol Hum. Rep. 4, 657-666.
154. Kato, Y., Tani, T., Sotomaru, Y., Kurokawa, K., Kalo, J., Dogichi, H., Yasue, H., and Tsunoda, Y. (1998). Eight calves cloned from somatic cells of a single adult. Science 282,2095-2098.
155. Keskintepe, L., Morton, P. C, Smith, S. E., Tucker, M. J., Simplicio, A. A., and Brackett, B. G. (1997). Caprine blastocyst formation following intracytoplasmic sperm injection and defined culture. Zygote 5, 261-265.
156. Kessel, R. G., (1992). Annulate lamellae: Last frontier in cellular organelles. Int. Rev. Cytol. 133, 43-120.
157. Kim, N.-H., Simerly, C, Funahashi, H., Schatten, G., and Day, B. N. (1996). Microtubule organization in porcine oocytes during fertilization and parthenogenesis. Biol. Reprod. 54, 1397-1404.
158. Kimura, Y., and Yanagimachi, R. (1995a). Mouse oocytes injected with testicular spermatozoa or round spermatids can develop into normal offspring. Development 121, 2397-2405.
159. Kimura, Y., and Yanagimachi, R. (1995b). Development of normal mice from oocytes injected with secondary spermatocyte nuclei. Biol. Reprod. 53, 855-862.
160. Kimura, Y., and Yanagimachi, R. (1995c) Intracytoplasmic sperm injection in the mouse. Biol. Reprod. 52, 709-720.
161. Kimura, Y., and Yanagimachi, R., Kuretake, S., Bortkiewicz, H., Perry, A. C. F., and Yanagimachi, H. (1998). Analysis of mouse oocyte activation suggests the involvement of sperm perinuclear material. Biol. Reprod. 58, 1407-1415.
162. King, W. A., Shepherd, D. L., Plante, L., Lavoir, M.-C, Looney, C. R., and Barnes, F. L. (1996). Nucleolar and mitochondrial morphology in bovine embryo reconstructed by nuclear transfer. Mol. Reprod. Dev. 44, 499-506.
163. Kleene, K. C., Smith, J., Bozorgzadeh, A., Harris, M., Hahn, L., Karimpour, I., and Gerstel, J. (1990). Sequence and developmental expression of the mRNA encoding the selenoprotein of the sperm mitochondrial capsule in the mouse. Dev. Biol. 137, 395-402.
164. Kopecny, V., Flechon, J. E., Camous, S., and Fulka, J., Jr. (1989). Nucleologenesis and the onset of transcription in the eight-cell bovine embryo: Fine-structural autoradiographic study. Mol. Reprod. Dev. 1, 79-90.
165. Kopecny, V., and Pavlok, A. (1975). Incorporation of Arginine-3H into chromatin of mouse eggs shortly after sperm penetration. Histochemistry 45, 341-345.
166. Korley, R., Pouresmaeili, F., and Oko, R. (1997). Analysis of the protein composition of the mouse sperm perinuclear theca and characterization of its major protein constituent. Biol. Reprod. 57, 1426-1432.
167. Krukowska, A., Wielkopolska, E., Czolowska, R., Maleszewski, M., and Tarkowski, A. K. (1998). Mouse oocytes and parthenogentic eggs lose the ability to be penetrated by spermatozoa after fusion with zygotes. Zygote 6, 321-328.
168. Krzanowska, H. (1982). Toluidine blue staining reveals changes in chromatin stabilization of mouse spermatozoa during epididymal maturation and penetration of ova. J. Reprod. Pert. 64, 97-101.
169. Kupker, W., Diedrich, K., and Edwards, R. G. (1998). Hum. Reprod. 13(Suppl. 1), 20-32.
170. Lalli, M., and Clermont, Y. (1981). Structural changes of the head components of the rat spermatid during late spermiogenesis. Am. J. Anat. 160, 419-434.
171. Lam, D. M. K., Furrer, R., and Bruce, W. R. (1970). The separation, physical characterization, and differentiation kinetics of spermatogonial cells of the mouse. Proc. Natl. Acad. Sci. USA 65, 192-199.
172. Laurincik, J., Hyttel, P., Daran, V., Eckert, J., Lucas-Hahn, A., Pivko, J., Niemann, H., Brem, G., and Schellander, K. A. (1998). Detailed analysis of pronucleus development in bovine zygotes in vitro: Cell-cycle chronology and ultrastructure. Mol. Reprod. Dev. 50, 192-199.
173. Laurincik, J., Hyttel, P., and Kopecny, V. (1995). DNA synthesis and pronucleus development in pig zygotes obtained in vivo: An autoradiographic and ultrastructural study. Mol. Reprod. Dev. 40, 325-432.
174. Lavoir, M. G, Kelk, D., Rumph, N., Barnes, F., Betteridge, K. J., and King, W. A. (1997). Transcription and translation in bovine nuclear transfer embryos. Biol. Reprod. 57,204-213.
175. Lee, J. W., Kirn, N. H., Lee, H. T., and Chung, K. S. (1998). Microtubule and chromatin organization during the first cell-cycle following intracytoplasmic injection of round spermatid into porcine oocytes. Mol. Reprod. Dev. 50, 221-228.
176. Le Guen, P., and Crozet, N. (1989). Microtubule and centrosome distribution during sheep fertilization. Eur. J. Cell Biol. 48, 239-249.
177. Lestienne, P., Reynier, P., Chrétien, M.-F., Penisson-Benier, I., Malthiery, Y., and Rohmer, V. (1997). Oligoasthenospermia associated with multiple mitochondria! DNA rearrangements. Mol. Hum. Rep. 3, 811-814.
178. Leyton, L., and Saling, P. (1989). 95 kd sperm proteins bind ZP3 and serve as tyrosine kinase substrates in response to zona binding. Cell 57, 1123-30.
179. Lightlowlers, R., Chinnery, P., Turnbull, D., and Howell, N. (1997). Mammalian mitochondrial genetics: Heredity, heteroplasmy and disease. Trends Genet. 13, 450-455.
180. Lin, P., and Clarke, H. J. (1996). Somatic histone HI microinjected into fertilized mouse eggs is transported into the pronuclei but does not disrupt subsequent preimplantation development. Mol. Reprod, Dev. 44, 185-192.
181. Long, C. R. Duncan, R. P., and Robl, J. M. (1997). Isolation and characterization of MPM-2-reactive sperm proteins: Homology to components of the outer dense fibers and segmented columns. Biol. Reprod. 57, 246-254.
182. Long, C. R., Pinto-Correia, C., Duby, R. T., Ponce de Leon, A., Boland, M. P., Roche, J. F., and Robl, J. M. (1993). Chromatin and microtubule morphology during the first cell cycle in bovine zygotes. Mol. Reprod. Dev. 36, 23-32.
183. Longo, F. J. (1975). Ultrastructural analysis of artificially activated rabbit eggs. J. Exp. Zool. 192, 87-112.
184. Longo, F. J. (1976). Sperm aster in rabbit zygotes: Its structure and function. J. Cell Biol. 69, 539-547.
185. Longo, F. J. (1989). Incorporation and dispersal of sperm surface antigens in plasma membranes of inseminated sea urchin (Arbacia punctulata) eggs and oocytes. Dev. Biol. 131, 37-43.
186. Longo, F. J., and Cook, S. (1991). Formation of the perinuclear theca in spermatozoa of diverse mammalian species: Relationship of the manchette and multiple band polypeptides. Mol. Reprod. Dev. 28, 380-393.
187. Longo, F. J., Krohne, G., and Franke, W. W. (1987). Basic proteins of the perinuclear theca of mammalian spermatozoa and spermatids: A novel class of cytoskeletal elements. J. Cell Biol. 105, 1105-1120.
188. Lu, Z. H., Sittman, D. B., Brown, D. T., Munshi, R., and Leno, G. H. (1997). Histone Hl modulates DNA replication through multiple pathways in Xenopiis egg extract. J. Cell Sci. 110, 2745-2758.
189. Luetjens, C. M., Payne, C, and Schatten, G. (1999). Non-random chromosome positioning in human sperm and sex chromosome anomalies following intracytoplasmic sperm injection (ICSI). Lancet 353, 1240.
190. Macas, E., Imthurn, B., Roselli, M., and Keller, P. J. (1996a). Chromosome analysis of single-and multipronucleated human zygotes proceeded after the intracytoplasmic sperm injection procedure. J. Assist. Reprod. Genet. 13, 127-132.
191. Macas, E., Imthurn, B., Roselli, M., and Keller, P. J. (1996b). The chromosomal complements of multipronuclear human zygotes resulting from intracytoplasmic sperm injection. Hum Reprod. 11, 2496-2501.
192. Macaulay, C., and Forbes, D. J. (1996). Assembly of the nuclear pore: Biochemically distinct steps revealed with NEM, GTPgS, and BAPTA. J. Cell Biol. 132, 5-20.
193. Maeda, Y., Yanagimachi, H., Tateno, H., Usui, N., and Yanagimachi, R. (1998). Decondensation of the mouse sperm nucleus within the interphase nucleus. Zygote 6, 39-45.
194. Manandhar, G., Sutovsky, P., Joshi, H. C., Stearns, T., and Schatten, G. (1998). Centrosome reduction during mouse spermiogenesis. Dev. Biol. 203, 424-434.
195. Marchington, D. R., Hartshorne, G. M., Barlow, D., and Poulton, J. (1997). Homopolymeric tract heteroplasmy in mtDNA from tissues and single oocytes-support for a genetic bottleneck. Am. J. Hum. Genet. 60, 408-416.
196. Masui, Y. (1982). Oscillatory activity of maturation promoting factor (MPF) in extracts of Rana pipiens eggs. J. Exp. Zool. 24, 389-399.
197. Masui, Y., and Clarke, H. J. (1979). Oocyte maturation. Int. Rev. Cylol. 57, 185-282.
198. Max, B. (1992). This and that: Hair pigments, the hypoxic basis of life and the Virgilian journey of the spermatozoon. Trends Phannacol. Sci. 13, 272-276.
199. McLaughlin, E. A., Frayne, J., Barker, H. L., Jury, J. A., Jones, R., Ford, W. C., and Hall, L. (1997). Cloning and sequence analysis of rat fertilin alpha and beta: Developmental expression, processing and immunolocalization. Mol. Hum. Reprod. 3, 801-809.
200. McNally, F. J., Okawa, K. Iwamatsu, A., and Vale, R. D. (1996). Katanin, the microtubulesevering ATPase, is concentrated at centrosomes. J. Cell Sci. 109, 561-567.
201. Meier, E., Miller, B. R., and Forbes, D. J. (1995). Nuclear pore complex assembly studied with a biochemical assay for annulate lamellae formation. J. Cell Biol. 129, 1459-1472.
202. Meirelles, F. V., Bordignon, V., Watanabe, Y. F., Watanabe, M. R., Dayan, A., Lobo, R. B., Garcia, J. M., and Smith, L. C. (1999). Zygote reconstructions among Bos indiens and Bos taurus cattle and consequences on mitochondria! inheritance. Theriogenology 51, 209.
203. Meister, A., and Anderson, M. E. (1983). Glutathione. Annu. Rev. Biocliem. 52, 711-760.
204. Merdes, A., and Cleveland, D. W. (1996). Pathways of spindle pole formation: Different mechanisms: Conserved components. J. Cell Biol. 138, 953-956.
205. Moos, J., Visconti, P. E., Moore, G. D., Schultz, R. M., and Kopf, G. S. (1995). Potential role of mitogen-activated protein kinase in pronuclear envelope assembly and disassembly following fertilization of mouse eggs. Biol. Reprod. 53, 692-699.
206. Mortiz, M., Braunfeld, M. B., Fung, J. C., Sedat, J. W., Alberts, B., and Agard, D. A. (1995). Three-dimensional structural characterization of centrosomes from early Drosphila embryos. J. Cell Biol. 130, 1149-1159.
207. Myles, D. G., and Primakoff, P. (1997). Why did the sperm cross the cumulus? To get to the oocyte. Functions of the sperm surface proteins PH-20 and fertilin in arriving at, and fusing with, the egg. Biol. Reprod. 56, 320-327.
208. Navara, C. S., First, N. L., and Schatten, G. (1994). Microtubule organization in the cow during fertilization, polyspermy, parthenogenesis, and neclear transfer: The role of the sperm aster. Dev. Biol. 162, 29-40.
209. Navara, C. S., First, N. L., and Schatten, G. (1996a). Phenotypic variations among paternal centrosomes are expressed within the zygote as varied microtubule length and sperm aster organization: Correlations between centrosome activity and developmental success. Proc. Natl. Acad. Sci. USA 93, 5384-5388.
210. Navara, C. S., Hewitson, L., Simerly, C. R., Sutovsky, P., and Schatten, G. (1996b). The implications of a paternally derived centrosome during human fertilization: Consequences for reproduction and the treatment of male factor infertility. Am. J. Reprod. Immun. 37, 39-49.
211. Navara, C. S., Simerly, C, Compton, D. A., and Schatten, G. (1996c). Maternal NuMA is required for nuclear formation and aster organization during fertilization: NuMA reorganization is microtubule independent. Mol. Biol. Cell 7/Suppl., 208a.
212. Navara, C. S., Zoran, S. S., Salisbury, J. L., Simerly, C, Stearns, T., and Schatten, G. (1995). Recruitment of maternal γ-tubulin to the bovine sperm centrosome. Mol. Biol. Cell. 61 Suppl., 39a.
213. Newport, J. W., (1987). Nuclear reconstitution in vitro: Stages of assembly around proteinfree DNA. Cell 48, 205-217.
214. Newport, J. W., Wilson, K. L., and Dunphy, W. G. (1990). A lamin-independent pathway for nuclear envelope assembly. J. Cell Biol 111, 2247-2259.
215. Nishioka, D., Porter, D. C., Trimmer, J. S., and Vacquier, V. D. (1987). Dispersal of sperm surface antigens in the plasma membranes of polyspermically fertilized sea urchin eggs. Exp. Cell Res. 173, 628-632.
216. Ogonuki, N., Sankai, T., Cho, F., Sato, K., and Yoshikawa, Y. (1998). Comparison of two methods of assisted fertilization in cynomolgus monkeys (Macaco fascicularis): Intracytoplasmic sperm injection and partial zona dissection followed by insemination. Hum. Reprod. 13, 2555-2560.
217. Ogura, A., Wakayama, T., Suzuki, O., Shin, T. Y., Matsuda, J., and Kobayashi, Y. (1997). Chromosomes of mouse primary spermatocytes undergo meiotic divisions after incorporation into homologous immature oocytes. Zygote 5, 177-182.
218. Okabe, M., Nagira, M., Kawai, Y., Matzno, S., Mimura, T., and Mayumi, T. (1990). A human sperm antigen possibly involved in binding and/or fusion with zona-free hamster eggs. Fertil. Steril, 54, 1121-1126.
219. Okabe, M., Yagasaki, M., Oda, H., Matzno, S., Kohama, Y., and Mimura, T. (1988). Effect of a monoclonal anti-mouse sperm antibody (OBF13) on the interaction of mouse sperm with zona-free mouse and hamster eggs. J. Reprod. Immunol. 13, 211-219.
220. Oko, R. (1995). Developmental expression and possible role of perinuclear theca proteins of mammalian spermatozoa. Reprod. Fertil. Dev. 7, 777-797.
221. Oko, R., and Clermont, Y. (1988). Isolation, structure and protein composition of the perforatorium of rat spermatozoa. Biol. Reprod. 39, 673-687.
222. Oko, R., and Clemont, Y. (1998). Spermiogenesis. In "Encyclopedia of Reproduction" (E, Knobil and J. D. Neil, eds.), Vol. IV., pp. 602-609. Academic Press, San Diego.
223. Oko, R., and Maravei, D. (1994). Protein composition of the perinuclear theca of bull spermatozoa. Biol. Reprod. 50, 1000-1014.
224. Oko, R., and Maravei, D. (1995). Distribution and possible role of perinuclear theca proteins during bovine spermiogenesis. Microsc. Res. Tech. 32, 520-532.
225. Oko, R., and Morales, C. R. (1994). A novel testicular protein, with sequence similarities to a family of lipid binding proteins, is a major component of the rat sperm perinuclear theca. Dev. Dial. 166, 235-245.
226. Olson, G. E., and Winfrey, V. P. (1988). Characterization of the postacrosomal sheath of bovine spermatozoa. Gamete Res. 20, 329-342.
227. Olson, G. E., and Winfrey, V. P. (1992). Structural organization of surface domains of sperm mitochondria. AM. Reprod. Dev. 33, 89-98.
228. Palacios, M. J., Joshi, H. C, Simerly, C, and Schatten, G. (1993). γ-tubulin reorganization during mouse fertilization and early development. J. Cell Sci. 104, 383-389.
229. Palazzo, R. E., Vaisberg, E., Cole, R. W., and Rieder, C. L. (1992). Centriole duplication in lysates of Spisula solodissima oocytes. Science 256, 219-221.
230. Palermo, G., Joris, H., Devroey, P., and Van Steirteghem, A. C. (1992). Pregnancies after intracytoplasmic sperm injection of single spermatozoon into an oocyte. Lancet 340,17-18.
231. Pallini, V., Baccetti, B., and Burini, A. G. (1979). A peculiar cysteine-rich polypeptide related to some unusual properties of mammalian sperm mitochondria: In "The Spermatozoon" (D. W. Fawcett and J. M. Bedford, eds.), pp. 141-151. Urban and Schwartzenberg, Baltimore Munich.
232. Panté, N., and Aebi, U. (1996). Sequential binding of import ligands to distinct nuclear pore regions during their nuclear import. Science 273,1729-1732.
233. Paranko, J., Longo, F., Potts, J., Krohne, G., and Franke, W. W. (1988). Widespread occurrence of calicin, a basic cytoskeletal protein of sperm cells, in diverse mammalian species. Differentiation 38, 21-27.
234. Parrington, J., Swann, K., Schevchenko, V. I., Sesay, A. K., and Lai, F. A. (1996). Calcium oscillations in mammalian eggs triggered by a soluble sperm factor. Nature 379, 364-368.
235. Parry, T. W., and Prather, R. S. (1995). Carry-over of mRNA during nuclear transfer in pigs. Reprod. Nutr. Dev. 35, 313-318.
236. Pasteels, J.J. (1963). Sur l'origine de la membrane nucléarie du pronucleus ♂ chez le mollusque bivalve Barnea Candida (Étude au microscopie électronique). In "Bulletin de 1" Académie Royale de Belgique (Classe de Sciences)," pp. 329-336.
237. Perreault, S. D. (1990). Regulation of sperm nuclear reactivation during fertilization. In "Fertilization in Mammals," (B. D. Bavister, J. Cummins, and E. R. S. Roldan, eds.), pp. 285-296. Serono Symposia, Norwell.
238. Perreault, S. D., Barbee, S. D., Elstein, K. H., Zucker, R. M., and Keefer, C. L. (1988). Interspecies differences in the stability of mammalian sperm nuclei assessed in vivo by sperm microinjection and in vitro by flow cytometry. Biol. Reprod. 39, 157-167.
239. Perreault, S. D., Wolf, R. A., and Zirkin, B. R. (1984). The role of disulfide bond reduction during mammalian sperm nuclear decondensation in vivo. Dev. Biol. 101,160-167.
240. Perry, A. C, Gichuhi, P. M., Jones, R., and Hall, L. (1995). Cloning and analysis of monkey fertilin reveals novel alpha subunit isoforms. Biochem. J. 307, 843-850.
241. Persson, J. W., Peters, G. B., and Saunders, D. M. (1996). Genetic consequences of ICSI. Is ICSI associated with risks of genetic disease? Implications for counseling, practice and research. Hum. Reprod. 11, 921-932.
242. Pfaller R. Smythe, C., and Newport, J. W. (1991). Assembly/disassembly of the nuclear envelope membrane: Cell cycle-dependent binding of nuclear membrane vesicles to chromatin in vitro. Cell 65, 209-217.
243. Phillips, D. M. (1974). "Spermiogenesis." Academic Press, New York.
244. Philpott, A., Leno, G. H., and Laskey, R. A. (1991). Sperm decondensation in Xenopus egg cytoplasm is mediated by nucleoplasmin. Cell 65, 569-578.
245. Pickworth, S., Yerganian, G., and Chang, M. C. (1968). Fertilization and early development in the Chinese hamster, Cricetiilus griseiis. Anal. Rec. 162, 197-208.
246. Pinto-Correia, C, Collas, P., Ponce de Leon, A., and Robl, J. M. (1993). Chromatin and microtubule organization in the first cell cycle in rabbit parthenotes and nuclear transplant embryos. Mol. Reprod. Dev. 34, 33-42.
247. Pinto-Correia, C., Poccia, D. L., Chang, T., and Robl, J. M. (1994). Dephosphorylation of sperm midpiece antigens initiates aster formation in rabbit oocytes. Proc. Natl. Acad. Sci. USA 91, 7894-7898.
248. Plante, Y., Schmutz, S. M., and Lang, K. D. M. (1992). Restriction fragment length polymorphism in the mitochondrial DNA of cloned cattle. Tlieriogenohgy 38, 897-904.
249. Plusa, B., Ciemerych, M. A., Borsuk, E., and Tarkowski, A. K. (1997). Transcription and DNA replication of sperm nuclei introduced into blastomeres of 2-cell mouse embryos. Zygote 5, 289-299.
250. Poccia, D., and Collas, P. (1996). Transforming sperm nuclei into male pronuclei in vivo and in vitro. In "Current Topics in Developmental Biology" (R. A. Pedersen and G. P. Schatten, eds.), Vol. 34, pp. 25-88. Academic Press, San Diego.
251. Primakoff, P., Hyatt, H., and Myles, D. G. (1985). A role for the migrating sperm surface antigen PH-20 in guinea pig sperm binding to the egg zona pellucida. J. Cell Biol. 101,2239-2244.
252. Raff, J. W. (1996). Centrosomes and microtubules: Welded with a ring. Trends Cell Biol. 6, 248-251.
253. Ramarao, C. S., Myles, D. G., White, J. M., and Primakoff, P. (1996). Initial evaluation of fertilin as an immunocontraceptive antigen and molecular cloning of the cynomolgus monkey fertilin beta subunit. Mol. Reprod. Dev. 43, 70-75.
254. Rankin, T. L., Tong, Z. B., Castle, P. E., Lee, E., Gore-Langton, R., Nelson, L. M., and Dean, J. (1998). Human ZP3 restores fertility in Zp3 null mice without affecting order-specific sperm binding. Development 125, 2415-2424.
255. Reik, W., Romer, L, Barton, S. C, Surani, M. A. Howlett, S. H., and Klose, J. (1993). Adult phenotype in the mouse can be affected by epigenetic events in the early embryo. Development 119, 933-942.
256. Reinsch, S., and Gonczy, P. (1998). Mechanisms of nuclear positioning. J. Cell Sci. III, 2283-2295.
257. Reinsch, S., and Karsenti, E. (1997). Movement of nuclei along microtubules in Xenopits egg extracts. Curr. Biol. 7, 211-214.
258. Reyes, J. G., Diaz, A., Osses, N., Opazo, C, and Benos, D. (1997). On stage single cell identification of rat spermatogenic cells. Biol. Cell 89, 53-66.
259. Reynier, P., Chretien, M. F., Savagner, F., Larcher, G., Rohmer, V., Barriere, P., and Malthiery, Y. (1998). Long PCR analysis of human gamete mtDNA suggests defective mitochondrial maintenance in spermatozoa and supports the bottleneck theory for oocytes. Biochem. Biophys. Res. Commun. 252, 373-377.
260. Rho, G.-J., Kawarsky, S., Johnson, W., Kochchar, K., and Betteridge, K. J. (1998). Sperm and oocyte treatments to improve the formation of male and fe,ale pronuclei and subsequent development following intracytoplasmic sperm injection into bovine oocytes. Biol Reprod. 59, 918-924.
261. Riffo, M. S., and Parraga, M. (1997). Role of phospholipase A2 in mammalian sperm-egg fusion: Development of hamster oolemma fusibility by lysophosphatidylcholine. J. Exp. Zool. 279, 81-88.
262. Rochwerger, L., Cohen, D. J., and Cuasnicu, P. S. (1992). Mammalian sperm-egg fusion: The rat egg has complementary sites for a sperm protein that mediates gamete fusion. Dev. Biol. 153, 83-90.
263. Romrell, L. J., Belve, A. R. and Fawcet, D. W. (1976). Separation of mouse spermatogenic cells by sedimentation velocity: A morphological characterization. Dev. Biol. 49, 119-131.
264. Rybouchkin, A, Dozortsev, D., Pelinck, M. J., De Sutler P., and Dhont, M. (1996). Analysis of oocyte activating capacity and chromosomal complement of round-headed human spermatozoa by their injection into mouse oocytes. Hum. Reprod. 11, 2170-2175.
265. Sadowy, S., Tomkin, G., Munne, S., Ferrara-Congedo, T., and Cohen, J. (1998). Impaired development of zygotes with uneven pronuclear size. Zygote 6, 137-141.
266. Saling, P. M., Irons, G., and Waibel, R. (1985). Mouse sperm antigens that participate in fertilization. I. Inhibition of sperm fusion with the egg plasma membrane using monoclonal antibodies. Biol. Reprod. 33, 515-526.
267. Sanders, M. A., and Salisbury, J. L. (1989). Centrin-mediated microtubule severing during flagellar excision in Chlamydomonas reinhardtii, J. Cell Biol. 108,1751-1760.
268. Sasagawa, I., Kuretake, S., Eppig, J. J., and Yanagimachi, R. (1998). Mouse primary spermatocytes can complete two meiotic divisions within the oocyte cytoplasm. Biol. Reprod. 58, 248-254.
269. Sathananthan, A. H., Kola, I., Osborne, J., Trounson, A., Ng, S. C., Bongso, A., and Ratnam, S. S. (1991). Centrioles at the beginning of human development. Proc. Natl. Acad. Sci. USA 88, 4806-4810.
270. Sathananthan, A. H., Ratnam, S. S., Ng, S. C., Tarin, J. J., Gianaroli, L., and Trounson, A. (1996). The sperm centriole: Its inheritance, replication and perpetuation in early human embryos. Hum. Reprod. 11, 345-356.
271. Sathananthan, A. H., Szell, A., Ng, S. C., Kausche, A., Lacham-Kaplan, O., and Trounson, A. (1997a). Is the acrosome reaction a prerequisite for sperm incorporation after intracytoplasmic sperm injection? Reprod. Fertil. Dev. 9, 703-709.
272. Sathananthan, A. H., Tatham, B., Dharmawardena, V., Grills, B., Lewis, I., and Trounson, A. (1997b). Inheritance of sperm centrioles and centrosomes in bovine embryos. Arch. Androl. 38, 37-48.
273. Sato, Y., Miyazaki, S., Shikano, T., Mitsuhashi, N., Takeuchi, H., Mikoshiba, K., and Kuwabara, Y. (1998). Adenophostin, a potent agonist of the inositol 1,4,5-trisphosphate receptor, is useful for fertilization of mouse oocytes injected with round spermatids leading to normal offspring. Biol. Reprod. 58, 867-873.
274. Schalles, U., Shao, X., Van der Hoorn, F. A., and Oko, R. (1998). Developmental expression of the 84 kDa ODF sperm protein: Localization to both the cortex and medulla of outer dense fibers and to the connecting piece. Dev. Biol., 199, 250-260.
275. Schatten, G. (1994). The centrosome and its mode of inheritance: The reduction of the centrosome during gametogenesis and its restoration during fertilization. Dev. Biol. 165, 229-335.
276. Schatten, G., Maul, G. G., Schatten, H., Chaly, N., Simerly, C., Balczon, R., and Brown, D. L. (1985a). Nuclear lamins and peripheral nuclear antigens during fertilization and embryogenesis in mice and sea urchins. Proc. Natl. Acad. Sci. USA 82, 4727-4731.
277. Schatten, G., Simerly, C., and Schatten, H. (1985b). Microtubule configurations during fertilization, mitosis, and early development in the mouse and the requirement for egg microtubulemediated motility during mammalian fertilization. Proc. Natl. Acad. ScL USA 82,4152-4156.
278. Schatten, G., Simerly, C., and Schatten, H. (1991). Maternal inheritance of centrosomes in mammals? Studies on parthenogenesis and polyspermy in mice. Proc. Natl. Acad. Sci. USA 88, 6785-6789.
279. Schatten, G., Hewitson, L., Simerly, C., Sutovsky, P., and Huszar, G. (1998). Cell and molecular biological challenges of ICSI: A.R.T. before science? J. Law, Med. & Ethics, 26, 5-13.
280. Schatten, H., Schatten, G., Mazia, D., Balczon, R., and Simerly, C. (1986). Behavior of centrosomes during fertilization and cell division in mouse oocytes and sea urchin eggs. Proc. Natl. Acad. Sci. USA 83, 105-109.
281. Schatten, H., Simerly, C., Maul, G., and Schatten, G. (1989). Microtubule assembly is required for the formation of the pronuclei, nuclear lamin acquisition, and DNA synthesis during mouse, but not sea urchin, fertilization. Gamete Res. 23, 309-322.
282. Schultz, R. M., and Kopf, G. S. (1995). Molecular basis of mammalian egg activation. In "Current Topics in Developmental Biology" (R. A. Pedersen and G. P. Schatten, eds.), Vol. 30, pp. 21-62. Academic Press, San Diego.
283. Sciaky, N., Presley, J., Smith, C., Zaal, K. J., Cole, N., Moreira, J. E. Terasaki, M., Sigga, E., and Lippincott-Schwartz, J. (1997). Golgi tubule traffic and the effects of brefeldin A visualized in living cells. J. Cell Biol. 139, 1137-1155.
284. Sette, C, Bevilacqua, A., Bianchini, A., Mangia, F., Geremia, R., and Rossi, P. (1997). Parthenogenetic activation of mouse eggs by microinjection of a truncated c-kit tyrosine kinase present in spermatozoa. Development 124, 2267-2274.
285. Shalgi, R., Magnus, A., Jones, R., and Phillips, D. M. (1994). Fate of sperm organelles during early embryogenesis in the rat. Mol. Reprod. Dev. 37, 264-271.
286. Sherratt, E. J., Thomas, A. \V., and Alcolado, J. C. (1997). Mitochondrial DNA defects: A widening clinical spectrum of disorders. Clin. Sci. 92, 225-235.
287. Shilling, FM., Magie C. R., and Nuccitelli, R., (1998). Voltage-dependent activation of frog eggs by a sperm surface disintegrin peptide. Dev. Biol. 202, 113-124.
288. Silber, S. J., Verheyen, G., and Van Steirteghem, A. C. (1998). Spermatid conception. Hum. Reprod. 13, 2976-2979.
289. Simerly, C., and Schatten, G. (1993). Techniques for localization of specific molecules in oocytes and embryos. Methods Enzymol. 225, 516-552.
290. Simerly, C., Wu, G., Zoran, S., Ord, T., Rawlins, R., Jones, J., Navara, C., Gerrity, M., Rinehart, J., Binor, Z., Asch, R., and Schatten, G. (1995). The paternal inheritance of the centrosome, the cell's microtubule-organizing center, in humans and the implications for infertility. Nature Med. 1, 47-53.
291. Simerly, C. R., Haawisto, A. J., Hewitson, L. C, Sutovsky, P., Navara, C. S., and Schatten, G. (1996). The molecular dissection and reconstitution of the centrosome during human fertilisation: Implications for infertility. S. Afr. J. Sci. 92, 548-557.
292. Simerly, C. R., Hecht, N. B., Goldberg, E., and Schatten, G. (1993). Tracing the incorporation of the sperm tail in the mouse zygote and early embryo using an anti-testicular alpha-tubulin antibody. Dev. Biol. 158, 536-548.
293. Simpson, J. L. (1998). Are anomalies increased after ART and ICSI? In "Fertility and Reproductive Medicine" (R. D. Kempers, J. Cohen, A. F. Haney, and J. B. Younger, eds.), pp. 199-209. Eisevier Science, Amsterdam.
294. Smith, L. C, and Alcivar, A. A. (1993). Cytoplasmic inheritance and its effects on development and performance. J. Reprod. Fertil Suppl. 48, 31-43.
295. Smith, L. C, Silverside, D. W., and Alcivar, A. A. (1991). The development of reconstituted mouse zygotes with mitochondria of mixed origin. J. Reprod. Fertil. Abstr. Ser. 8, 17.
296. Sofikitis, N. V., Toda, T., Miyagawa, I., Zavos, P. M., Pasyianos, P., and Mastelou, E. (1996). Beneficial effects of electrical stimulation before round spermatid nuclei injections into rabbit oocytes on fertilization and subsequent embryonic development. Fertil. Steril. 65, 176-185.
297. Sofikitis, N., Yamamoto, Y., Isoyama, T., and Miyagawa, I. (1997). The early haploid gamete develops a capacity for fertilization after the coalescence of the proacrosomal granules. Hum. Reprod. 12, 2713-2719.
298. Sofikitis, N. V., Yamamoto, Y., Miyagawa, L, Mekras, G., Mio, Y., Toda, T., Antypas, S., Kawamura, H., Kanakas, N., Antoniou, N., Loutradis, D., Mantzavinos, T., Kalianidis, K., and Agapitos, E. (1998). Ooplasmic injection of elongating spermatids for the treatment of nonobstructive azoospermia. Hum. Reprod. 13, 709-714.
299. Soloy, E., Kanka, J., Viuff, D., Smith, S. D., Callesen, H., and Greve, T. (1997). Time course of pronuclear deoxyribonucleic acid synthesis in parthenogenetically activated bovine oocytes. Biol. Reprod. 57, 27-35.
300. Sousa, M., Barros, A., and Tesarik, J. (1998). Current problems with spermatid conception. Hum. Reprod. 13,255-258.
301. Stearns, T., Evans, L., and Kirschner, M. (1991). γ-tubulin is a highly conserved component of the centrosome. Cell 65, 825-836.
302. Stearns, T., and Kirschner, M. (1994). In vitro reconstitution of centrosome assembly and function: The central role of γ-tubulin. Cell 76, 623-637.
303. St. John, J., and Barrat, C. L. R. (1997). Use of anucleate donor oocyte cytoplasm in recipient eggs. Lancet 350, 961.
304. St. John, J., Cooke, I. D., and Barrat, C. L. R. (1997). Mitochondrial mutations and male infertility. Nature Med. 3, 124-125.
305. Stricker, S. A., and Schatten, G. (1989). Nuclear envelope disassembly and nuclear lamina depolymerization during germinal vesicle breakdown in starfish. Dev. Biol. 135, 87-98.
306. Sutovsky, P., Hewitson, L., Simerly, C. R., Tengowski, M. W., Navara, C. S., Haavisto, A., and Schatten, G. (1996a). Intracytoplasmic sperm injection (ICSI) for rhesus monkey fertilization results in unusual chromatin, cytoskeletal, and membrane events, but eventually leads to pronuclear development and sperm aster assembly. Hum. Reprod. 11,1703-1712.
307. Sutovsky, P., Manandhar, G., and Schatten, G. (1999). Biogenesis of the centrosome during mammalian gametogenesis and fertilization. Protoplasma 206, 249-262.
308. Sutovsky, P., Moreno, R., and Schatten, G. (1998a). Sperm mitochondrial ubiquitination and a model explaining the strictly maternal mtDNA inheritance in mammals. Mol. Biol. Cell 9/Suppl., 309a.
309. Sutovsky. P., Navara, C. S., and Schatten, G. (1996b). The fate of the sperm mitochondria, and the incorporation, conversion and disassembly of the sperm tail structures during bovine fertilization in vitro. Biol. Reprod. 55, 1195-1205.
310. Sutovsky, P., Oko, R., Hewitson, L., and Schatten, G. (1997a). The removal of the sperm perinuclear theca and its association with the bovine oocyte surface during fertilization. Dev. Biol. 188, 75-84.
311. Sutovsky, P., Oko, R., Hewitson, L. C., Tengowski, M. W., and Schatten, G. (1997b). Involvement of oocyte microvillli and microfilaments in the removal of the sperm's perinuclear theca: A prerequisite for the success of mammalian fertilization. Mol. Biol. Cell 8/SuppI., 106a.
312. Sutovsky, P., and Schatten, G. (1997). Depletion of glutathione during oocyte maturation reversibly blocks the decondensation of the male pronucleus and pronuclear apposition during fertilization. Biol. Reprod. 56, 1503-1512.
313. Sutovsky, P., and Schatten, G. (1998). Structural aspects of mammalian fertilization: New discoveries and inspirations from the work of Daniel Szöllösi. Reprod. Nutr. Dev. 38, 629-641.
314. Sutovsky, P., Simerly, C., Hewitson, L., and Schatten, G. (1998b). Assembly of nuclear pore complexes and annulate lamellae promotes normal pronuclear development in fertilized mammalian oocytes. J. Cell Sci. III, 2841-2854.
315. Sutovsky, P., Tengowski, M. W., Navara, C. S., Zoran, S.S., and Schatten G. (1997c). Mitochondrial sheath movement and detachment in mammalian, but not non-mammalian, sperm induced by disulfide bond reduction. Mol. Reprod. Dev. 47, 79-86.
316. 2+ release in eggs at fertilization. Rev. Reprod. 1, 33-39.
317. Swann, K., Igusa, Y., and Miyazaki, S. (1989). Evidence for an inhibitory effect of protein kinase C on G-protein-mediated repetitive calcium transients in hamster eggs. EMBO J. 8, 3711-3718.
318. Szöllösi, D. (1965). The fate of the sperm middle-piece mitochondria in the rat egg. J. Exp. Zool. 159, 367-378.
319. Szöllösi, D. (1976). Oocyte maturation and paternal contribution to the embryo in mammals. Curr. Top. Pathol. 64, 9-27.
320. Szöllösi, D., Calarco, P., and Donahue, R. P. (1972). Absence of centrioles in the first and second meiotic spindles of mouse oocytes. J. Cell Set. 11, 521-541.
321. Szöllösi, D., and Hunter, R. H. F. (1973). Ultrastructural aspects of fertilization in the domestic pig: Sperm penetration and pronucleus formation. J. Anal. 116, 181-206.
322. Szöllösi, D., and Ozil, J. P. (1991). De novo formation of centrioles in parthenogenetically activated, diploidized rabbit embryos. Biol. Cell 72, 61-66.
323. Szöllösi, M. S., Adenot, P., and Szöllösi, D. (1996). Centrosomes with striated rootlets in rabbit zygotes. Zygote 4,173-179.
324. Szöllösi, M. S., and Szöllösi, D. (1988). "Blebbing" of the nuclear envelope of mouse zygotes, early embryos and hybrid cells. J. Cell Sci. 91, 257-267.
325. Tateno, H., and Kamiguchi, Y. (1999). Improvement of male pronuclear formation during cross-fertilization between Chinese hamster spermatozoa and Syrian hamster oocytes by nocodazole, and chromosome analysis of hybrid zygotes. Mol. Reprod. Dev. 52, 117-124.
326. Terasaki, M., Jaffe, L. A., Hunnicutt, G. R., and Hammer, J. A., III (1996). Structural change of the endoplasmic reticulum during fertilization: Evidence for loss of membrane continuity using the green fluorescent protein. Dev. Biol. 179, 320-328.
327. Tesarik, J. (1997). Sperm or spermatid conception? Fertil. Steril. 68, 214-216.
328. Tesarik, J., and Mendoza, C. (1996). Spermatid injection into human oocytes. I. Laboratory techniques and special features of zygote development. Hum. Reprod. 11, 772-779.
329. Tesarik, J., Mendoza, C., and Testart, J. (1995). Viable embryos from injection of round spermatid into oocytes. N. Engl. J. Afed. 333, 525.
330. Tipler, C. P., Hutchon, S. P., Hendil, K., Tanaka, K., Fishel, S., and Mayer, R. J. (1997). Purification and characterization of 26s proteasomes from human and mouse spermatozoa. Mol. Hum. Reprod. 3, 1053-1060.
331. Torroni, A., D'Urbano, L., Rengo, C., Scozzari, R., Sbracia, M., Manna, C., Cavazzini, C, and Sellitto, D. (1998). Intracytoplasmic injection of spermatozoa does not appear to alter the mode of mitochondrial DNA inheritance. Hum. Reprod. 13, 1747-1749.
332. Toshimori, K., Saxena, D. K., Tanii, I., and Yoshinaga, K. (1998). An MN9 antigenic molecule, equatorin, is required for successful sperm-oocyte fusion in mice. Biol. Reprod. 59, 22-29.
333. Ulitzur, N., Harel, A., Feinstein, N., and Gruenbaum, Y. (1992). Lamin activity is essential for nuclear envelope assembly in a Drospliila embryo cell-free extract. J. Cell Biol. 119,17-25.
334. Urch, U. A., and Patel, H. (1991). The interaction of boar sperm proacrosin with its natural substrate, the zona pellucida, and with polysulfated polysaccharides. Development 111, 1165-1172.
335. Usui, N. (1996). Morphological differences in nuclear materials released from hamster sperm heads at an early stage of incorporation into immature oocytes, mature oocytes, or fertilized eggs. AM. Reprod. Dev. 44, 132-140.
336. Usui, N., A. Ogura, Y. Kimura, and Yanagimachi, R. (1997). Sperm nuclear envelope: Breakdown of intrinsic envelope and de novo formation in hamster oocytes or eggs. Zygote 5, 35-46.
337. Usui, N., Ogura, A., and Yanagimachi, R. (1999). Ultrastructural changes in hamster spermatogenic cell nuclei after incorporation into homologous oocytes by electrofusion. Mol. Reprod. Dev. 52, 66-73.
338. Usui, N., and Yanagimachi, R. (1976). Behavior of hamster sperm nuclei incorporated into eggs at various stages of maturation, fertilization and early development. J. Ullrastrucl. Res. 57, 276-288.
339. Van Blerkom, J., Bell, H, and Henry, G. (1987). The occurrence, recognition and developmental fate of pseudo-multipronuclear eggs after in vitro fertilization of human oocytes. Hum. Reprod. 2, 217-225.
340. Van den Bergh, M., Bertrand, E., Biramane, J., and Englert, Y. (1995). Importance of breaking a spermatozoon's tail before intracytoplasmic injection: A prospective randomized trial. Hum. Reprod. 10, 2819-2820.
341. Vanderzwalmen, P., Zech, H., Birkenfeld, A., Yemini, M., Bertin, G., Lejeune, B., Nijs, M., Segal, L., Stecher, A., Vandamme, B., van Roosendaal, E., and Schoysman, R. (1997). Intracytoplasmic injection of spermatids retrieved from testicular tissue: Influence of testicu-lar pathology, type of selected spermatids and oocyte activation. Hum. Reprod. 12, 1203-1213.
342. Van Steirteghem, A., Nagy, S., Joris, H., Liu, J., Staessen, C, Smitz, J., Wisanto, A., and Devroey, P. (1993). High fertilization and implantation rates after intracytoplasmic sperm injections. Hum. Reprod. 8, 1061-1066.
343. Verheyen, G-, Crabbe, E., Joris, H., and Van Steirteghem, A. (1998). Simple and reliable identification of the human round spermatid by inverted phase-contrast microscopy. Hum. Reprod. 13,1570-1577.
344. Vidaeus, C. M., von Kapp-Herr, C., Golden, W. L., Eddy, R. L., Shows, T. B., and Herr, J. C. (1997). Human fertilin beta: Identification, characterization, and chromosomal mapping of an ADAM gene family member. Mol. Reprod. Dev. 46, 363-9.
345. Vigers, G. P., and Lohka, M. J. (1991). A distinct vesicle population targets membranes and pore complexes to the nuclear envelope in Xenopus eggs. J. Cell Biol. 112, 545-556.
346. Vignon, X., Chesne, P., Le Bourhis, D., Fléchon, J. E., Heyman, Y., and Renard, J. P. (1998). Developmental potential of bovine embryos reconstructed from enucleated matured oocytes fused with cultured somatic cells. C. R. Acad. Sci. HI. 321, 735-45.
347. Vorobjev, I. A., and Chentsov, Y. S. (1982). Centrioles in the cell cycle. I. Epithelial cells. J. Cell Biol. 93, 938-949.
348. Wakayama, T., Perry, A. C., Zuccotti, M., Johnson, K. R., and Yanagimachi, R. (1998). Fullterm development of mice from enucleated oocytes injected with cumulus cell nuclei. Nature 394, 369-374.
349. Wallace, D. C. (1994). Mitochondria! DNA sequence variation in human evolution and disease. Proc. Natl. Acad. Sci. USA 91, 8739-8746.
350. Wassarman, P. M. (1990). Profile of a mammalian sperm receptor. Development 108, 1-17.
351. Waters, S. I, and White, J. M. (1997). Biochemical and molecular characterization of bovine fertilin alpha and beta (ADAM 1 and ADAM 2): A candidate sperm-egg binding/fusion complex. Biol, Reprod. 56, 1245-1254.
352. Westendorf, J. M., Rao, P. N., and Gerace, L. (1994). Cloning of cDNAs for M-phase phosphoproteins recognized by the MPM2 monoclonal antibody and determination of the phosphorylated epitope. Proc. Natl. Acad. Sci. USA 91, 714-718.
353. Wilmut, I, Schnieke, A. E., McWhir, J., Kind, A. J., and Campbell, K. H. (1997). Viable offspring derived from fetal and adult mammalian cells. Nature 385, 810-813.
354. Wing, S. S., Bedard, N., Morales, C., Hingamp, P., and Trasler, J.
355. 17KB) highly expressed in rat testis. Biochem. J. 305, 125-132.
356. Wolfsberg.T. G., Bazan, J. F., Blobel, C. P., Myles, D. G., Primakoff, P., and White, J. M. (1993). The precursor region of a protein active in sperm-egg fusion contains a metalloprotease and a disintegrin domain: Structural, functional, and evolutionary implications. Proc. Natl. Acad. Sci. USA 90, 10783-10787.
357. Wolfsberg, T. G., Straight, P. D., Gerena, R. L., Huovila, A. P., Primakoff, P., Myles, D. G., and White, J. M. (1995). ADAM, a widely distributed and developmentally regulated gene family encoding membrane proteins with a disintegrin and metalloprotease domain. Dev. Biol. 169, 378-383.
358. Wolosker, H., Kline, D., Bian, Y., Blackshaw, S., Cameron, A. M., Fralich, T. J., Schnaar, R. L., and Snyder, S. H. (1998). Molecularly cloned mammalian gIucosamine-6-phosphate deaminase localizes to transporting epithelium and lacks oscillin activity. FASEB J. 12, 91-99.
359. Woolley, D. M., and Fawcett, D. W. (1973). The degeneration and disappearance of the centrioles during the development of the rat spermatozoon. Anat. Rec. 177, 289-301.
360. Wright, S. J., and Longo, F. J. (1988). Sperm nuclear enlargement in fertilized hamster eggs is related to meiotic maturation of the maternal chromatin. J. Exp. Zool. 247, 155-65.
361. \Vu, G.-J., Simerly, C., Zoran, S. S., Funte, L. R., and Schatten, G. (1996). Microtubule and chromatin dynamics during fertilization and early development in rhesus monkeys, and regulation by intracellular calcium ions. Biol. Reprod. 55, 260-270.
362. Xu, Y. S., Overton, W. R., Marmar, J. L., Leonard, J. C., McCoy Jr., J. P., Butler, G. H., and Li, H. (1998). Complete replication of human sperm genome in egg extracts form Xenopus laevis. Biol. Reprod. 58, 641-647.
363. Yamagata, K., Murayama, K., Okabe, M., Toshimori, K., Nakanishi, T., Kashiwabara, S., and Baba, T. (1998). Acrosin accelerates the dispersal of sperm acrosomal proteins during acrosome reaction. J. Biol. Chem. 273, 10470-10474.
364. Yamanaka, K., Sofikitis, N., and Miyagawa, I. (1997). Ooplasmic round spermatid nuclear injection procedures as an experimental treatment for nonobstructive azoospermia. J. Assist. Reprod. Genet. 14, 55-62.
365. Yanagimachi, R. (1994). Mammalian fertilization. In "The Physiology of Reproduction" (E. Knobil and J. D. Neill, eds.), 2nd Ed, pp. 189-317. Raven Press, New York.
366. Young, L. E., Sinclair, K. D., and Wilmut I. (1998). Large offspring syndrome in cattle and sheep. Rev. Reprod. 3, 155-163.
367. Yuan, R., Primakoff, P., and Myles, D. G. (1997). A role for the disintegrin domain of cyritestin, a sperm surface protein belonging to the ADAM family, in mouse sperm-egg plasma membrane adhesion and fusion. J. Cell Biol. 137, 105-112.
368. Zamboni, L., and Mastroianni, L. Jr. (1966). Electron microscopic studies of rabbit ova. I. The follicular oocyte. J. Ultrastruct. Res. 14, 95-117.
369. Zeviani, M., and Antozzi, C. (1997). Mitochondrial disorders. Mol. Hum. Rep. 3, 133-148.
370. Zheng, Y., Wong, M. L. Alberts, B., and Mitchison. T. (1995). Nucleation of microtubule assembly by a γ-tubulin-containing ring complex. Nature 378, 578-583.
371. Zoran, S., Simerly, C., Schoff. P., Stearns, T., Salisbury, J., and Schatten, G. (1994). Reconstitution of the human sperm centrosome in vitro. Mol. Biol. Cell 5/Suppl., 38a.
372. Zuelke, K. A., Jones, D. P., and Perreault S. D. (1997). Glutathione oxidation is associated with altered microtubule function and disrupted fertilization in mature hamster oocytes. Biol. Reprod. 57,1413-1419.