Molecular determinants of mexiletine structure for potent and use- dependent block of skeletal muscle sodium channels

Molecular Pharmacology

Volumn 57, Issue 2, 2000, Pages 268-277

  De Luca, Annamaria ^a   Natuzzi, Fedele ^a   Desaphy, Jean Francois ^a   Loni, Gabriella ^a   Lentini, Giovanni ^a   Franchini, Carlo ^a   Tortorella, Vincenzo ^a   Camerino, Diana Conte ^a,b  

^a UNIVERSITY OF BARI   (Italy)

^b Facolta di Farmacia   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ION CHANNEL; MEXILETINE; SODIUM CHANNEL;

ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG POTENCY; DRUG STRUCTURE; FROG; NONHUMAN; PRIORITY JOURNAL; SKELETAL MUSCLE; VOLTAGE CLAMP;

ANIMALS; ANTI-ARRHYTHMIA AGENTS; MEXILETINE; MUSCLE, SKELETAL; RANA ESCULENTA; SODIUM CHANNEL BLOCKERS; SODIUM CHANNELS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0033964620     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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