Synthesis of mexiletine stereoisomers and related compounds via S(N)Ar nucleophilic substitution of a Cr(CO)3-complexed aromatic fluoride

Journal of Organic Chemistry

Volumn 64, Issue 9, 1999, Pages 3373-3375

  Loughhead, David G ^a   Flippin, Lee A ^a   Weikert, Robert J ^a  

^a ROCHE BIOSCIENCE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG DERIVATIVE; MEXILETINE; MEXILETINE DERIVATIVE; UNCLASSIFIED DRUG;

CARDIOVASCULAR EFFECT; DRUG STRUCTURE; DRUG SYNTHESIS; NOTE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; REACTION ANALYSIS; STEREOISOMERISM; STEREOSPECIFICITY; STRUCTURE ANALYSIS;

EID: 0033617395     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo982287c     Document Type: Note

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