-
1
-
-
34548824527
-
Neoplasia
-
Saunders, St. Louis, Mo
-
1 Kumar V., Cotran R. S. and Robbins S. L. (1997) Neoplasia. In: Basic Pathology, 6th edn, pp. 531-580, Saunders, St. Louis, Mo
-
(1997)
Basic Pathology, 6th Edn
, pp. 531-580
-
-
Kumar, V.1
Cotran, R.S.2
Robbins, S.L.3
-
2
-
-
0013565075
-
The ras oncogcnc
-
Reddy E. P., Skalka A. M. and Curran T. (eds), Elsevier, Amsterdam
-
2 Lacal J. C. and Tronick S. R. (1988) The ras oncogcnc. In: The Oncogene Handbook, pp. 255-304, 535-550, Reddy E. P., Skalka A. M. and Curran T. (eds), Elsevier, Amsterdam
-
(1988)
The Oncogene Handbook
, pp. 255-304
-
-
Lacal, J.C.1
Tronick, S.R.2
-
3
-
-
0003353750
-
ras-p21 proteins: Switch devices for signal transduction
-
Lacal J. C. and McCormick F. (eds), CRC, Boca Raton, Fla
-
3 Cuadraro A., Carnero A. and Lacal J. C. (1993) ras-p21 proteins: switch devices for signal transduction. In: The ras Superfamily of GTPases, pp. 119-153, Lacal J. C. and McCormick F. (eds), CRC, Boca Raton, Fla
-
(1993)
The Ras Superfamily of GTPases
, pp. 119-153
-
-
Cuadraro, A.1
Carnero, A.2
Lacal, J.C.3
-
4
-
-
0026079628
-
The biochemistry of ras p21
-
4 Grand R. J. A. and Owen D. (1991) The biochemistry of ras p21. Biochem. J. 279: 609-631
-
(1991)
Biochem. J.
, vol.279
, pp. 609-631
-
-
Grand, R.J.A.1
Owen, D.2
-
6
-
-
0026659959
-
Specific isoprenoid modification is required for function of normal, but not oncogenic, Ras protein
-
6 Cox A. D., Hisaka M. M., Buss J. E. and Der C. J. (1992) Specific isoprenoid modification is required for function of normal, but not oncogenic, Ras protein. Mol. Cell. Biol. 12: 2606-2615
-
(1992)
Mol. Cell. Biol.
, vol.12
, pp. 2606-2615
-
-
Cox, A.D.1
Hisaka, M.M.2
Buss, J.E.3
Der, C.J.4
-
7
-
-
0001010670
-
Signal transduction from membrane to cytoplasm: Growth factors and membrane bound oncogene products increase phosphorylation and associated kinase activity
-
7 Morrison D. K., Kaplan D. R., Rapp U. R. and Roberts T. M. (1988) Signal transduction from membrane to cytoplasm: growth factors and membrane bound oncogene products increase phosphorylation and associated kinase activity. Proc. Nat. Acad. Sci. USA 85: 8855-8859
-
(1988)
Proc. Nat. Acad. Sci. USA
, vol.85
, pp. 8855-8859
-
-
Morrison, D.K.1
Kaplan, D.R.2
Rapp, U.R.3
Roberts, T.M.4
-
8
-
-
0027229556
-
Grb2 mediates the EGF-dependent activation of guanine nucleotide exchange on ras
-
8 Gale N. W., Kaplan S., Lowenstein E. J., Schlessinger J. and Bar-Sagi D. (1993) Grb2 mediates the EGF-dependent activation of guanine nucleotide exchange on ras. Nature 363: 88-92
-
(1993)
Nature
, vol.363
, pp. 88-92
-
-
Gale, N.W.1
Kaplan, S.2
Lowenstein, E.J.3
Schlessinger, J.4
Bar-Sagi, D.5
-
9
-
-
0027294981
-
The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the ras activator mSos1
-
9 Rozakis-Adcock M., Fernley R., Wade J., Pawson T. and Bowtell D. (1993) The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the ras activator mSos1. Nature 363: 83-85
-
(1993)
Nature
, vol.363
, pp. 83-85
-
-
Rozakis-Adcock, M.1
Fernley, R.2
Wade, J.3
Pawson, T.4
Bowtell, D.5
-
10
-
-
0027910431
-
Asociation of Sos ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation
-
10 Egan S. E., Giddins B. W., Brooks M. W., Buday L., Sizelan A. M. and Weinber R. A. (1993) Asociation of Sos ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation. Nature 363: 45-51
-
(1993)
Nature
, vol.363
, pp. 45-51
-
-
Egan, S.E.1
Giddins, B.W.2
Brooks, M.W.3
Buday, L.4
Sizelan, A.M.5
Weinber, R.A.6
-
11
-
-
0027161398
-
Complex formation between ras and raf and other protein kinases
-
11 Aelst L. V., Barr M., Marcus S., Polverino A. and Wigler M. (1993) Complex formation between ras and raf and other protein kinases. Proc. Nat. Acad. Sci. USA 90: 6213-6217
-
(1993)
Proc. Nat. Acad. Sci. USA
, vol.90
, pp. 6213-6217
-
-
Aelst, L.V.1
Barr, M.2
Marcus, S.3
Polverino, A.4
Wigler, M.5
-
12
-
-
0026739542
-
Ras controls coupling of growth factor receptors and protein kinase C in the membrane to raf-1 and B-raf protein serine kinascs in the cytosol
-
12 Troppmair J., Bruder J. T., App H., Cai H., Liptak L., Szeberényi J. et al. (1992) Ras controls coupling of growth factor receptors and protein kinase C in the membrane to raf-1 and B-raf protein serine kinascs in the cytosol. Oncogene 7: 1867-1873
-
(1992)
Oncogene
, vol.7
, pp. 1867-1873
-
-
Troppmair, J.1
Bruder, J.T.2
App, H.3
Cai, H.4
Liptak, L.5
Szeberényi, J.6
-
13
-
-
0027337519
-
Complexes of ras-GDP with raf-1 and the mitogen activated protein kinase kinase
-
13 Moodie S. A., Willumsen B. M., Weber M. J. and Wolfman A. (1993) Complexes of ras-GDP with raf-1 and the mitogen activated protein kinase kinase. Science 260: 1658-1660
-
(1993)
Science
, vol.260
, pp. 1658-1660
-
-
Moodie, S.A.1
Willumsen, B.M.2
Weber, M.J.3
Wolfman, A.4
-
14
-
-
0028153277
-
Activated Ras interacts with the Ral guanine nucleotide dissociation stimulator
-
14 Hofer F., Fields S., Schneider C. and Martin G. S. (1994) Activated Ras interacts with the Ral guanine nucleotide dissociation stimulator. Proc. Natl. Acad. Sci. USA 91: 11089-11093
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 11089-11093
-
-
Hofer, F.1
Fields, S.2
Schneider, C.3
Martin, G.S.4
-
15
-
-
0027986765
-
ralGDS family members interact with the effector loop of ras p21
-
15 Kikuchi A., Demo S. D., Ye Z. H., Chen Y. W. and Wiliams L. T. (1994) ralGDS family members interact with the effector loop of ras p21. Mol. Cell. Biol. 14: 7483-7491
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 7483-7491
-
-
Kikuchi, A.1
Demo, S.D.2
Ye, Z.H.3
Chen, Y.W.4
Wiliams, L.T.5
-
16
-
-
0028074316
-
Phosphatidylinositol-3-OH kinase as a direct target of Ras
-
16 Rodriguez-Viciana P., Warne P. H., Dhand R., Vanhaesebroeck B., Gout I., Fry M. J. et al. (1994) Phosphatidylinositol-3-OH kinase as a direct target of Ras. Nature 370: 527-532
-
(1994)
Nature
, vol.370
, pp. 527-532
-
-
Rodriguez-Viciana, P.1
Warne, P.H.2
Dhand, R.3
Vanhaesebroeck, B.4
Gout, I.5
Fry, M.J.6
-
17
-
-
0026695645
-
TCF by MAP kinase stimulates ternary complex formation at c-fos promoter
-
TCF by MAP kinase stimulates ternary complex formation at c-fos promoter. Nature 358: 414-417
-
(1992)
Nature
, vol.358
, pp. 414-417
-
-
Gille, H.1
Sharrocks, A.D.2
Shaw, P.E.3
-
18
-
-
0029160069
-
Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction
-
18 Burgering B. M. T. and Coffer P. J. (1995) Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction. Nature 376: 599-602
-
(1995)
Nature
, vol.376
, pp. 599-602
-
-
Burgering, B.M.T.1
Coffer, P.J.2
-
19
-
-
0028818914
-
Involvement of Ral GTPase in v-Src-induced phospholipase D activation
-
19 Jiang H., Luo J. Q., Urano T., Frankel P., Lu Z., Foster D. A. et al. (1995) Involvement of Ral GTPase in v-Src-induced phospholipase D activation. Nature 378: 409-412
-
(1995)
Nature
, vol.378
, pp. 409-412
-
-
Jiang, H.1
Luo, J.Q.2
Urano, T.3
Frankel, P.4
Lu, Z.5
Foster, D.A.6
-
21
-
-
0030968580
-
Rho GTPases and signaling networks
-
21 Van Aelst L. and D'Souza-Schorey C. (1997) Rho GTPases and signaling networks. Genes Dev. 11: 2295-2322
-
(1997)
Genes Dev.
, vol.11
, pp. 2295-2322
-
-
Van Aelst, L.1
Souza-Schorey, C.2
-
22
-
-
0027191250
-
Tumorigenic activity of rho genes from Aplysia californica
-
22 Perona R., Esteve P., Jiménez B., Ballestero R. P. and Lacal J. C. (1993) Tumorigenic activity of rho genes from Aplysia californica. Oncogene 8: 1285-1292
-
(1993)
Oncogene
, vol.8
, pp. 1285-1292
-
-
Perona, R.1
Esteve, P.2
Jiménez, B.3
Ballestero, R.P.4
Lacal, J.C.5
-
23
-
-
0028800305
-
Activation of Rac1, RhoA. And mitogen-activated protein kinases is required for
-
23 Khosravi-far R., Solski P. A., Clark G. J., Kinch M. S. and Der C. J. (1995) Activation of Rac1, RhoA. and mitogen-activated protein kinases is required for Ras transformation. Mol. Cell. Biol. 15: 6443-6453
-
(1995)
Ras Transformation. Mol. Cell. Biol.
, vol.15
, pp. 6443-6453
-
-
Khosravi-Far, R.1
Solski, P.A.2
Clark, G.J.3
Kinch, M.S.4
Der, C.J.5
-
24
-
-
0029057465
-
Critical role of Rho in cell transformation by oncogenic Ras
-
24 Prendergast G. C., Khosravi-Far R., Solski P. A., Kurzawa H., Lebowitz P. F. and Der C. J. (1995) Critical role of Rho in cell transformation by oncogenic Ras. Oncogene 10: 2289-2296
-
(1995)
Oncogene
, vol.10
, pp. 2289-2296
-
-
Prendergast, G.C.1
Khosravi-Far, R.2
Solski, P.A.3
Kurzawa, H.4
Lebowitz, P.F.5
Der, C.J.6
-
25
-
-
0028903247
-
An essential role for Rac in Ras transformation
-
25 Qiu R. G., Chen J., Kirn D., McCormick F. and Symons M. (1995) An essential role for Rac in Ras transformation. Nature 374: 457-459
-
(1995)
Nature
, vol.374
, pp. 457-459
-
-
Qiu, R.G.1
Chen, J.2
Kirn, D.3
McCormick, F.4
Symons, M.5
-
26
-
-
0031034469
-
Activation of the nuclear factor-kappaB by Rho, CDC42, and Rac-1 proteins
-
26 Perona R., Montaner S., Saniger L., Sanchez-Perez I., Bravo R. and Lacal J. C. (1997) Activation of the nuclear factor-kappaB by Rho, CDC42, and Rac-1 proteins. Genes Dev. 11: 463-475
-
(1997)
Genes Dev.
, vol.11
, pp. 463-475
-
-
Perona, R.1
Montaner, S.2
Saniger, L.3
Sanchez-Perez, I.4
Bravo, R.5
Lacal, J.C.6
-
27
-
-
0032557526
-
Multiple signalling pathways lead to the activation of the nuclear factor kappaB by the Rho family of GTPases
-
27 Montaner S., Perona R., Saniger L. and Lacal J. C. (1998) Multiple signalling pathways lead to the activation of the nuclear factor kappaB by the Rho family of GTPases. J. Biol. Chem. 273: 12779-12785
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 12779-12785
-
-
Montaner, S.1
Perona, R.2
Saniger, L.3
Lacal, J.C.4
-
28
-
-
0029015774
-
The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF
-
28 Hill C. S., Wynne J. and Treisman R. (1995) The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF. Cell 81: 1159-1170
-
(1995)
Cell
, vol.81
, pp. 1159-1170
-
-
Hill, C.S.1
Wynne, J.2
Treisman, R.3
-
29
-
-
0033605654
-
Activation of serum response factor by RhoA is mediated by the NF-KB and C EBP transcription factors
-
29 Montaner S., Perona R., Saniger L. and Lacal J. C. (1999) Activation of serum response factor by RhoA is mediated by the NF-KB and C EBP transcription factors. J. Biol. Chem. 274: 8506-8515
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 8506-8515
-
-
Montaner, S.1
Perona, R.2
Saniger, L.3
Lacal, J.C.4
-
32
-
-
0022408348
-
Experimental metastatic ability of H-ras-transformed NIH 3T3 cells
-
32 Bondy G. P., Wilson S. and Chambers A. F. (1985) Experimental metastatic ability of H-ras-transformed NIH 3T3 cells. Cancer Res. 45: 6005-6009
-
(1985)
Cancer Res.
, vol.45
, pp. 6005-6009
-
-
Bondy, G.P.1
Wilson, S.2
Chambers, A.F.3
-
33
-
-
0022377328
-
Harvey ras induction of metastatic potential depends upon oncogene activation and the type of recipient cell
-
33 Muschel R. J., Williams J. E., Lowy D. R. and Liotta L. A. (1985) Harvey ras induction of metastatic potential depends upon oncogene activation and the type of recipient cell. Am. J. Pathool. 121: 1-8
-
(1985)
Am. J. Pathool.
, vol.121
, pp. 1-8
-
-
Muschel, R.J.1
Williams, J.E.2
Lowy, D.R.3
Liotta, L.A.4
-
34
-
-
0029867784
-
Different metastatic potentials of ras-and src-transformed BALB/c 3T3 A31 cells
-
34 Tatsuka M., Ota T., Yamagishi N., Kashihara Y., Wada M., Matsuda N. et al. (1996) Different metastatic potentials of ras-and src-transformed BALB/c 3T3 A31 cells. Mole. Carcinogenesis 15: 300-308
-
(1996)
Mole. Carcinogenesis
, vol.15
, pp. 300-308
-
-
Tatsuka, M.1
Ota, T.2
Yamagishi, N.3
Kashihara, Y.4
Wada, M.5
Matsuda, N.6
-
35
-
-
0025793649
-
Ras levels and metalloproteinase activity in normal versus neoplastic ras mammary tissues
-
35 Ballin M., Mackay A. R., Hartzler J. L., Nason A., Pelina M. D. and Thorgeirsson U. P. (1991) Ras levels and metalloproteinase activity in normal versus neoplastic ras mammary tissues. Clin. Exp. Metastasis 9: 179-189
-
(1991)
Clin. Exp. Metastasis
, vol.9
, pp. 179-189
-
-
Ballin, M.1
Mackay, A.R.2
Hartzler, J.L.3
Nason, A.4
Pelina, M.D.5
Thorgeirsson, U.P.6
-
36
-
-
0024374607
-
Metastatic potential of cloned murine melanoma cells transfected with activated c-Ha-ras
-
36 Price J. E., Aukerman S. L., Ananthaswamy H. N., McIntyre B. W., Schackert G., Schackert H. K. et al. (1989) Metastatic potential of cloned murine melanoma cells transfected with activated c-Ha-ras. Cancer Res. 49: 4274-4281
-
(1989)
Cancer Res.
, vol.49
, pp. 4274-4281
-
-
Price, J.E.1
Aukerman, S.L.2
Ananthaswamy, H.N.3
McIntyre, B.W.4
Schackert, G.5
Schackert, H.K.6
-
37
-
-
0024330674
-
The ras oncogene and tumor metastasis: Observations on murine cells transfected with activated human c-Ha-ras
-
37 Wallace J. S., Hayle A. J., Syms A. J., Cairney M., Tutty B., Gazzard A. et al. (1989) The ras oncogene and tumor metastasis: observations on murine cells transfected with activated human c-Ha-ras. Differentiation 41: 208-215
-
(1989)
Differentiation
, vol.41
, pp. 208-215
-
-
Wallace, J.S.1
Hayle, A.J.2
Syms, A.J.3
Cairney, M.4
Tutty, B.5
Gazzard, A.6
-
38
-
-
0031577698
-
Rho proteins induce metastatic properties in vivo
-
38 Peso L. del, Hernandez-Alcoceba R., Embade N., Carnero A., Esteve P., Paje C. et al. (1997) Rho proteins induce metastatic properties in vivo. Oncogene 15: 3047-3057
-
(1997)
Oncogene
, vol.15
, pp. 3047-3057
-
-
Del Peso, L.1
Hernandez-Alcoceba, R.2
Embade, N.3
Carnero, A.4
Esteve, P.5
Paje, C.6
-
39
-
-
0023635251
-
Rodent fibroblast tumours expressing human myc and ras genes: Growth, metastasis and endogenous oncogene expression
-
39 Wyllie A. H., Rose K. A., Morris R. G., Steel C. M., Foster E. and Spandidos D. A. (1987) Rodent fibroblast tumours expressing human myc and ras genes: growth, metastasis and endogenous oncogene expression. Br. J. Cancer 56: 251-259
-
(1987)
Br. J. Cancer
, vol.56
, pp. 251-259
-
-
Wyllie, A.H.1
Rose, K.A.2
Morris, R.G.3
Steel, C.M.4
Foster, E.5
Spandidos, D.A.6
-
40
-
-
0025063658
-
Genetic instability and the acquisition of metastatic ability by rat mammary cancer cells following v-H-ras oncogene transfection
-
40 Ichikawa T., Kiprianou N. and Isaacs J. T. (1990) Genetic instability and the acquisition of metastatic ability by rat mammary cancer cells following v-H-ras oncogene transfection. Cancer Res. 50: 6349-6357
-
(1990)
Cancer Res.
, vol.50
, pp. 6349-6357
-
-
Ichikawa, T.1
Kiprianou, N.2
Isaacs, J.T.3
-
41
-
-
0025745484
-
H-ras expression, genetic instability, and acquisition of metastatic ability by rat prostalic cancer cells following v-H-ras oncogene transfection
-
41 Ichikawa T., Schalken J. A., Ichikawa Y., Steinberg G. D. and Isaacs J. T. (1991) H-ras expression, genetic instability, and acquisition of metastatic ability by rat prostalic cancer cells following v-H-ras oncogene transfection. Prostate 18: 163-172
-
(1991)
Prostate
, vol.18
, pp. 163-172
-
-
Ichikawa, T.1
Schalken, J.A.2
Ichikawa, Y.3
Steinberg, G.D.4
Isaacs, J.T.5
-
42
-
-
0022599216
-
Enhanced spontaneous metastasis of mouse carcinoma cells transfected with an activated c-Ha-ras-1 gene
-
42 Vousden K. H., Eccles S. A., Purvies H. and Marshall C. J. (1986) Enhanced spontaneous metastasis of mouse carcinoma cells transfected with an activated c-Ha-ras-1 gene. Int. J. Cancer 37: 425-433
-
(1986)
Int. J. Cancer
, vol.37
, pp. 425-433
-
-
Vousden, K.H.1
Eccles, S.A.2
Purvies, H.3
Marshall, C.J.4
-
43
-
-
0026658820
-
K-ras point mutations in human colorectal carcinomas: Relation to aneuploidy and metastasis
-
43 Suchy B., Zietz C. and Rabes H. M. (1992) K-ras point mutations in human colorectal carcinomas: relation to aneuploidy and metastasis. Int. J. Cancer 52: 30-33
-
(1992)
Int. J. Cancer
, vol.52
, pp. 30-33
-
-
Suchy, B.1
Zietz, C.2
Rabes, H.M.3
-
44
-
-
0024327557
-
Ras oncogene and the acquisition of metastasizing properties by rectal adenocarcinoma
-
44 Michelassi F., Erroi F., Roncella M. and Block G. E. (1989) Ras oncogene and the acquisition of metastasizing properties by rectal adenocarcinoma. Dis. Colon Rectum 32: 665-668
-
(1989)
Dis. Colon Rectum
, vol.32
, pp. 665-668
-
-
Michelassi, F.1
Erroi, F.2
Roncella, M.3
Block, G.E.4
-
45
-
-
0031900232
-
Ras p21 immunostaining in early stage squamous cervical carcinoma: Relationship with lymph nodal involvement and 72 kDa-metalloproteinase index
-
45 Garzetti G. G., Ciavattini A., Lucarini G., Goteri G., Nictolis M. D., Romanini C. et al. (1998) Ras p21 immunostaining in early stage squamous cervical carcinoma: relationship with lymph nodal involvement and 72 kDa-metalloproteinase index. Anticancer Res. 18: 609-613
-
(1998)
Anticancer Res.
, vol.18
, pp. 609-613
-
-
Garzetti, G.G.1
Ciavattini, A.2
Lucarini, G.3
Goteri, G.4
Nictolis, M.D.5
Romanini, C.6
-
46
-
-
0028676036
-
Correlation of differences in modulation of ras expression with metastatic competence of mouse mammary tumor subpopulations
-
46 Shekhar P. V. and Miller F. R. (1994) Correlation of differences in modulation of ras expression with metastatic competence of mouse mammary tumor subpopulations. Invasion Metastasis 14: 27-37
-
(1994)
Invasion Metastasis
, vol.14
, pp. 27-37
-
-
Shekhar, P.V.1
Miller, F.R.2
-
47
-
-
0022550298
-
Elevated ras oncogene expression correlates with lymph node metastases in breast cancer patients
-
47 Lundy J, Grimson R., Mishriki Y., Chao S., Ovarez S., Fromowitz F. et al. (1986) Elevated ras oncogene expression correlates with lymph node metastases in breast cancer patients. J. Clin. Oncol. 4: 1321-1325
-
(1986)
J. Clin. Oncol.
, vol.4
, pp. 1321-1325
-
-
Lundy, J.1
Grimson, R.2
Mishriki, Y.3
Chao, S.4
Ovarez, S.5
Fromowitz, F.6
-
48
-
-
0026011783
-
Correlation of mutations of oncogene c-Ha-ras at codon 12 with metastasis and survival of gastric cancer patients
-
48 Deng G. R., Liu X. H. and Wang J. R. (1991) Correlation of mutations of oncogene c-Ha-ras at codon 12 with metastasis and survival of gastric cancer patients. Oncogene Res. 6: 33-38
-
(1991)
Oncogene Res.
, vol.6
, pp. 33-38
-
-
Deng, G.R.1
Liu, X.H.2
Wang, J.R.3
-
49
-
-
0000533549
-
Biological function of Aplysia californica rho gene
-
NATO Advanced Science Institute Series, Plenum, New York
-
49 Ballestero R. P., Esteve P., Perona R., Jiménez B. and Lacal J. C. (1991) Biological function of Aplysia californica rho gene. In: The Superfamily of ras Related Genes, pp. 237-242, NATO Advanced Science Institute Series, vol. A220, Plenum, New York.
-
(1991)
The Superfamily of Ras Related Genes
, vol.A220
, pp. 237-242
-
-
Ballestero, R.P.1
Esteve, P.2
Perona, R.3
Jiménez, B.4
Lacal, J.C.5
-
50
-
-
0031974721
-
Overexpression of the rhoC gene correlates with progression of ductal adenocarcinoma of the pancreas
-
50 Suwa H., Ohshio G., Imamura T., Watanabe G., Arii S., Imamura M. et al. (1998) Overexpression of the rhoC gene correlates with progression of ductal adenocarcinoma of the pancreas. Br. J. Cancer 77: 147-152
-
(1998)
Br. J. Cancer
, vol.77
, pp. 147-152
-
-
Suwa, H.1
Ohshio, G.2
Imamura, T.3
Watanabe, G.4
Arii, S.5
Imamura, M.6
-
51
-
-
0031239882
-
The small GTPases Cdc42Hs, Rac1 and RhoG delineate Raf-independent pathways that cooperate to transform NIH3T3 cells
-
51 Roux P., Gauthier-Rouviere C., Doucel-Brutin S. and Fort P. (1997) The small GTPases Cdc42Hs, Rac1 and RhoG delineate Raf-independent pathways that cooperate to transform NIH3T3 cells. Curr. Biol. 7: 629-637
-
(1997)
Curr. Biol.
, vol.7
, pp. 629-637
-
-
Roux, P.1
Gauthier-Rouviere, C.2
Doucel-Brutin, S.3
Fort, P.4
-
52
-
-
0028225439
-
Identification of an invasion-inducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins
-
52 Habets G. G. M, Scholtes E. H. M., Zuydgeest D., Kammen R. A. v. d., Stam J. C., Berns A. et al. (1994) Identification of an invasion-inducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins. Cell 77: 537-549
-
(1994)
Cell
, vol.77
, pp. 537-549
-
-
Habets, G.G.M.1
Scholtes, E.H.M.2
Zuydgeest, D.3
Kammen, R.A.V.D.4
Stam, J.C.5
Berns, A.6
-
53
-
-
0029079431
-
A role for Rac in Tiam1-in-duced membrane ruffling and invasion
-
53 Michiels F., Habets G. G. M., Stam J. C., van der Kammen R. A. and Collard J. G. (1995) A role for Rac in Tiam1-in-duced membrane ruffling and invasion. Nature 375: 338-340
-
(1995)
Nature
, vol.375
, pp. 338-340
-
-
Michiels, F.1
Habets, G.G.M.2
Stam, J.C.3
Van Der Kammen, R.A.4
Collard, J.G.5
-
54
-
-
0031459917
-
Cdc42 and Rac1 induce integrin-mediated cell molility and invasiveness through PI(3)K
-
54 Keely P. J., Westwick J. K., Whitehead I. P., Der C. J. and Parise L. V. (1997) Cdc42 and Rac1 induce integrin-mediated cell molility and invasiveness through PI(3)K. Nature 390: 632-636
-
(1997)
Nature
, vol.390
, pp. 632-636
-
-
Keely, P.J.1
Westwick, J.K.2
Whitehead, I.P.3
Der, C.J.4
Parise, L.V.5
-
55
-
-
0028986034
-
The Ras-related protein Cdc42Hs and brudykinin promote formation of peripheral actin microspikes and filopodia in Swiss 3T3 fibroblasts
-
55 Kozma R., Ahmed S., Best A. and Lim L. (1995) The Ras-related protein Cdc42Hs and brudykinin promote formation of peripheral actin microspikes and filopodia in Swiss 3T3 fibroblasts. Mol. Cell. Biol. 15: 1942-1952
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 1942-1952
-
-
Kozma, R.1
Ahmed, S.2
Best, A.3
Lim, L.4
-
56
-
-
0028961293
-
Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia
-
56 Nobes C. D. and Hall A. (1995) Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia. Cell 81: 53-56
-
(1995)
Cell
, vol.81
, pp. 53-56
-
-
Nobes, C.D.1
Hall, A.2
-
57
-
-
0029828456
-
Involvement of the small GTPase rho in integrin-mediated activation of mitogen-activated protein kinase
-
57 Renshaw M. W., Toksoz D. and Schwartz M. A. (1996) Involvement of the small GTPase rho in integrin-mediated activation of mitogen-activated protein kinase., J. Biol. Chem. 271: 21691-21694
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 21691-21694
-
-
Renshaw, M.W.1
Toksoz, D.2
Schwartz, M.A.3
-
58
-
-
0032030656
-
Integrins and GTPases in tumour cell growth, motility and invasion
-
58 Keely P., Parise L. and Juliano R. (1998) Integrins and GTPases in tumour cell growth, motility and invasion. Trends Cell Biol. 8: 101-106
-
(1998)
Trends Cell Biol.
, vol.8
, pp. 101-106
-
-
Keely, P.1
Parise, L.2
Juliano, R.3
-
59
-
-
0032572557
-
Integrin-mediated signals regulated by members of the rho family of GTPases
-
59 Clark E. A., King W. G., Brugge J. S., Symons M. and Hynes R. O. (1998) Integrin-mediated signals regulated by members of the rho family of GTPases. J. Cell. Biol. 142: 573-586
-
(1998)
J. Cell. Biol.
, vol.142
, pp. 573-586
-
-
Clark, E.A.1
King, W.G.2
Brugge, J.S.3
Symons, M.4
Hynes, R.O.5
-
60
-
-
0032560744
-
Rapid recruitment of p120RasGAP and its associated protein, p190RhoGAP, to the cytoskeleton during integrin mediated cell-substrate interaction
-
60 Sharma S. V. (1998) Rapid recruitment of p120RasGAP and its associated protein, p190RhoGAP, to the cytoskeleton during integrin mediated cell-substrate interaction. Oncogene 17: 271-281
-
(1998)
Oncogene
, vol.17
, pp. 271-281
-
-
Sharma, S.V.1
-
61
-
-
0031806711
-
Rac regulates integrin-mediated spreading and increased adhesion of T lymphocytes
-
61 D'Souza-Schorey C., Boettner B. and Van Aelst L. (1998) Rac regulates integrin-mediated spreading and increased adhesion of T lymphocytes. Mol. Cell. Biol. 18: 3936-3946
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 3936-3946
-
-
D'souza-Schorey, C.1
Boettner, B.2
Van Aelst, L.3
-
62
-
-
0031594710
-
Activation of beta1 integrin stimulates tyrosine phosphorylation of p190RhoGAP and membrane-protusive activities at invadipodia
-
62 Nakahara H., Mueller S. C., Nomizu M., Yamada Y., Yeh Y. and Chen W. T. (1998) Activation of beta1 integrin stimulates tyrosine phosphorylation of p190RhoGAP and membrane-protusive activities at invadipodia. J. Biol. Chem. 273: 9-12
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 9-12
-
-
Nakahara, H.1
Mueller, S.C.2
Nomizu, M.3
Yamada, Y.4
Yeh, Y.5
Chen, W.T.6
-
63
-
-
0030904698
-
Regulation of cadherin-mediated adhesion by the small GTP-binding protein Rho in small cell lung carcinoma cells
-
63 Tokman M. G., Porter R. A. and Williams C. L. (1997) Regulation of cadherin-mediated adhesion by the small GTP-binding protein Rho in small cell lung carcinoma cells. Cancer Res. 57: 1785-1793
-
(1997)
Cancer Res.
, vol.57
, pp. 1785-1793
-
-
Tokman, M.G.1
Porter, R.A.2
Williams, C.L.3
-
64
-
-
0032493903
-
Role of IQGAP1, a target of the small GTPases Cdc42 and Rac1, in regulation of E-cadherin-mediated cell-cell adhesion
-
64 Kuroda S., Fukata M., Nakagawa M., Fujii K., Nakamura T., Ookubo T. et al. (1998) Role of IQGAP1, a target of the small GTPases Cdc42 and Rac1, in regulation of E-cadherin-mediated cell-cell adhesion. Science 281: 832-835
-
(1998)
Science
, vol.281
, pp. 832-835
-
-
Kuroda, S.1
Fukata, M.2
Nakagawa, M.3
Fujii, K.4
Nakamura, T.5
Ookubo, T.6
-
65
-
-
0031576553
-
Regulation of cell-cell adhesion of MDCK cells by Cdc42 and Rac1 small GTPases
-
65 Kuroda S., Fukata M., Fujii K., Nakamura T., Izawa I. and Kaibuchi K. (1997) Regulation of cell-cell adhesion of MDCK cells by Cdc42 and Rac1 small GTPases. Biochem. Biophys. 240: 430-435
-
(1997)
Biochem. Biophys.
, vol.240
, pp. 430-435
-
-
Kuroda, S.1
Fukata, M.2
Fujii, K.3
Nakamura, T.4
Izawa, I.5
Kaibuchi, K.6
-
66
-
-
0030698191
-
Inhibition of invasion of epithelial cells by Tiam1-Rac signaling
-
66 Horkijk P. L., Klooster J. P . ten, Kammen R. A. van der, Michelis F., Oomen L. C. and Collard J. G. (1997) Inhibition of invasion of epithelial cells by Tiam1-Rac signaling. Science 278: 1464-1466
-
(1997)
Science
, vol.278
, pp. 1464-1466
-
-
Horkijk, P.L.1
Klooster, J.P.T.2
Van Der Kammen, R.A.3
Michelis, F.4
Oomen, L.C.5
Collard, J.G.6
-
67
-
-
0027524424
-
A link between ras and metastatic behaviour of tumor cells: Ras induces CD44 promoter activity and leads to low-level expression of metastasis-specific variants of CD44 in CREF cells
-
67 Hofmann M., Rudy W., Gunthert U., Zimmer S. G., Zawadzki V., Zoller M. et al. (1993) A link between ras and metastatic behaviour of tumor cells: ras induces CD44 promoter activity and leads to low-level expression of metastasis-specific variants of CD44 in CREF cells. Cancer Res. 53: 1516-1521
-
(1993)
Cancer Res.
, vol.53
, pp. 1516-1521
-
-
Hofmann, M.1
Rudy, W.2
Gunthert, U.3
Zimmer, S.G.4
Zawadzki, V.5
Zoller, M.6
-
68
-
-
0031829163
-
Activation of both MAP kinase and phosphatidylinositide 3-kinase by Ras is required for hepalocyte growth factor/scatter factor-induced adherens junction disassembly
-
68 Potempa S. und Ridley A. J. (1998) Activation of both MAP kinase and phosphatidylinositide 3-kinase by Ras is required for hepalocyte growth factor/scatter factor-induced adherens junction disassembly. Mol. Biol. Cell. 9: 2185-2200
-
(1998)
Mol. Biol. Cell.
, vol.9
, pp. 2185-2200
-
-
Potempa, S.1
Ridley, A.J.2
-
69
-
-
0031471232
-
A point mutation in the MET oncogene abrogates metastasis without affecting transformation
-
69 Giordano S., Bardelli A., Zhen Z , Menard S., Ponzetto C. and Comoglio P. M. (1997) A point mutation in the MET oncogene abrogates metastasis without affecting transformation. Proc. Natl. Acad. Sci. USA 94: 13868-13872
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 13868-13872
-
-
Giordano, S.1
Bardelli, A.2
Zhen, Z.3
Menard, S.4
Ponzetto, C.5
Comoglio, P.M.6
-
70
-
-
0031854558
-
The roles of hepatocyte growth factor/scatter factor and met receptor in human cancers
-
70 To C. T. and Tsao M. S. (1998) The roles of hepatocyte growth factor/scatter factor and met receptor in human cancers. Oncol. Rep. 5: 1013-1024
-
(1998)
Oncol. Rep.
, vol.5
, pp. 1013-1024
-
-
To, C.T.1
Tsao, M.S.2
-
71
-
-
0030723163
-
Platelet-derived growth factor and fibronectin-stimulated migration are differentially regulated by Rac and extracellular signal-regulated kinase pathways
-
71 Anand-Apte B., Zetter B. R., Viswanathan A., Qiu R. G., Chen J., Ruggieri R. et al. (1997) Platelet-derived growth factor and fibronectin-stimulated migration are differentially regulated by Rac and extracellular signal-regulated kinase pathways. J. Biol. Chem. 272: 30688-30692
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 30688-30692
-
-
Anand-Apte, B.1
Zetter, B.R.2
Viswanathan, A.3
Qiu, R.G.4
Chen, J.5
Ruggieri, R.6
-
72
-
-
0029093670
-
The chemotactic response to PDGFBB: Evidence of a role for Ras
-
72 Kundra V., Anand-Apte B., Feig L. A. and Zetter B. R. (1995) The chemotactic response to PDGFBB: evidence of a role for Ras. J. Cell Biol. 130: 725-731
-
(1995)
J. Cell Biol.
, vol.130
, pp. 725-731
-
-
Kundra, V.1
Anand-Apte, B.2
Feig, L.A.3
Zetter, B.R.4
-
73
-
-
0030931217
-
Regulation of cell motilily by mitogen-activated protein kinase
-
73 Klemke R. L., Cai S., Giannini A. L., Gallagher P. J., de Lanerolle P. and Cheresh D. A. (1997) Regulation of cell motilily by mitogen-activated protein kinase. J. Cell Biol. 137:481-492
-
(1997)
J. Cell Biol.
, vol.137
, pp. 481-492
-
-
Klemke, R.L.1
Cai, S.2
Giannini, A.L.3
Gallagher, P.J.4
De Lanerolle, P.5
Cheresh, D.A.6
-
74
-
-
0030977123
-
-
74 Kureishi Y., Kobayashi S., Amano M., Kimura K., Kanaide H. and Nakano T. et al. (1997) Rho-associated kinase directly induces smooth muscle contraction through myosin light chain phosphorylation. 272: 12257-12260
-
(1997)
Rho-associated Kinase Directly Induces Smooth Muscle Contraction through Myosin Light Chain Phosphorylation
, vol.272
, pp. 12257-12260
-
-
Kureishi, Y.1
Kobayashi, S.2
Amano, M.3
Kimura, K.4
Kanaide, H.5
Nakano, T.6
-
75
-
-
0032570796
-
Small GTP-binding protein Rho stimulates the actomyosin system, leading to invasion of tumor cells
-
75 Yoshioka K., Matsumura F., Akedo H. and Itoh K. (1998) Small GTP-binding protein Rho stimulates the actomyosin system, leading to invasion of tumor cells. J. Biol. Chem. 273: 5146-5154
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 5146-5154
-
-
Yoshioka, K.1
Matsumura, F.2
Akedo, H.3
Itoh, K.4
-
77
-
-
0032577699
-
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate
-
77 Maehama T. and Dixon J. E. (1998) The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate. J. Biol. Chem. 273: 13375-13378
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 13375-13378
-
-
Maehama, T.1
Dixon, J.E.2
-
78
-
-
15144353776
-
Role of substrates and products of PI 3-kinase in regulating activation of Rac-relaled guanosine triphosphatases by Vav
-
78 Han J, Luby-Phelps K., Das B., Shu X., Xia Y., Mosteller R. D. et al. (1998) Role of substrates and products of PI 3-kinase in regulating activation of Rac-relaled guanosine triphosphatases by Vav. Science 279: 558-560
-
(1998)
Science
, vol.279
, pp. 558-560
-
-
Han, J.1
Luby-Phelps, K.2
Das, B.3
Shu, X.4
Xia, Y.5
Mosteller, R.D.6
-
79
-
-
0032486198
-
Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN
-
79 Tamura M., Gu J., Matsumoto K., Aota S., Parsons R. and Yamada K. M. (1998) Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN. Science 280: 1614-1617
-
(1998)
Science
, vol.280
, pp. 1614-1617
-
-
Tamura, M.1
Gu, J.2
Matsumoto, K.3
Aota, S.4
Parsons, R.5
Yamada, K.M.6
-
80
-
-
0029784472
-
Independence of metastatic ability and extravasation: Metastalic ras-transformed and control fibroblasts extravasate equally well
-
80 Koop S., Schmidt E. F., MacDonald I. C., Morris V. L., Khokha R., Grattan M. et al. (1996) Independence of metastatic ability and extravasation: metastalic ras-transformed and control fibroblasts extravasate equally well. Proc. Natl. Acad. Sci. USA 93: 11080-11084
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 11080-11084
-
-
Koop, S.1
Schmidt, E.F.2
Macdonald, I.C.3
Morris, V.L.4
Khokha, R.5
Grattan, M.6
-
81
-
-
0031655802
-
Multistep nature of metastatic inefficiency: Dormancy of solitary cells after succesful extravasation and limited survival of early micrometastases
-
81 Luzzi K. J., MacDonald I. C., Schmidt E. E., Kerkvliet N., Morris V. L., Chambers A. F. et al. (1998) Multistep nature of metastatic inefficiency: dormancy of solitary cells after succesful extravasation and limited survival of early micrometastases. Am. J. Pathol. 153: 865-873
-
(1998)
Am. J. Pathol.
, vol.153
, pp. 865-873
-
-
Luzzi, K.J.1
Macdonald, I.C.2
Schmidt, E.E.3
Kerkvliet, N.4
Morris, V.L.5
Chambers, A.F.6
-
82
-
-
0031826467
-
Chemokine-induced monocyte transmigration requires cdc42-mediated cytoskeletal changes
-
82 Weber K. S., Klickstein L. B., Weber P. C. and Weber C. (1998) Chemokine-induced monocyte transmigration requires cdc42-mediated cytoskeletal changes. Eur. J. Immunol. 28: 2245-2251
-
(1998)
Eur. J. Immunol.
, vol.28
, pp. 2245-2251
-
-
Weber, K.S.1
Klickstein, L.B.2
Weber, P.C.3
Weber, C.4
-
83
-
-
0030728116
-
Role of cadherins in the transendothelial migration of melanoma cells in culture
-
83 Sandig M., Voura E. B., Kalnins V. I. and Siu C. H. (1997) Role of cadherins in the transendothelial migration of melanoma cells in culture. Cell Motil. Cytoskeleton 38: 351-364
-
(1997)
Cell Motil. Cytoskeleton
, vol.38
, pp. 351-364
-
-
Sandig, M.1
Voura, E.B.2
Kalnins, V.I.3
Siu, C.H.4
-
84
-
-
0028326346
-
Induction of fibroblast 92 kDa gelatinase/type IV collagenase expression by direct contact with metastatic tumor cells
-
84 Himelstein B. P., Canete-Soler R., Bernhard E. J. and Muschel R. J. (1994) Induction of fibroblast 92 kDa gelatinase/type IV collagenase expression by direct contact with metastatic tumor cells. J. Cell Sci. 107: 477-486
-
(1994)
J. Cell Sci.
, vol.107
, pp. 477-486
-
-
Himelstein, B.P.1
Canete-Soler, R.2
Bernhard, E.J.3
Muschel, R.J.4
-
85
-
-
0031915048
-
Overview of matrix metalloproteinase expression in cultured human cells
-
85 Giambernardi T. A., Grant G. M., Taylor G. P., Hay R. J., Maher V. M., McCormick J. J. et al. (1988) Overview of matrix metalloproteinase expression in cultured human cells. Matrix Biol. 16: 483-496
-
(1988)
Matrix Biol.
, vol.16
, pp. 483-496
-
-
Giambernardi, T.A.1
Grant, G.M.2
Taylor, G.P.3
Hay, R.J.4
Maher, V.M.5
McCormick, J.J.6
-
86
-
-
0028951760
-
A radiation-induced murine ovarian granulosa cell tumor line: Introduction of v-ras gene potentiates a high metastatic ability
-
86 Yanagihara K., Nii M., Tsumuraya M., Numoto M., Seito T. and Seyama T. (1995) A radiation-induced murine ovarian granulosa cell tumor line: introduction of v-ras gene potentiates a high metastatic ability. Jpn. J. Cancer Res. 86: 347-356
-
(1995)
Jpn. J. Cancer Res.
, vol.86
, pp. 347-356
-
-
Yanagihara, K.1
Nii, M.2
Tsumuraya, M.3
Numoto, M.4
Seito, T.5
Seyama, T.6
-
87
-
-
0028897627
-
Reduction of translation initiation factor 4E decreases the malignancy of ras-transformed cloned embryo fibroblasts
-
87 Graff J. R., Boghaert E. R., De Benedetti A., Tudor D. L., Zimmer C. C., Chan S. K. et al. (1995) Reduction of translation initiation factor 4E decreases the malignancy of ras-transformed cloned embryo fibroblasts. Int. J. Cancer 60: 255-263
-
(1995)
Int. J. Cancer
, vol.60
, pp. 255-263
-
-
Graff, J.R.1
Boghaert, E.R.2
De Benedetti, A.3
Tudor, D.L.4
Zimmer, C.C.5
Chan, S.K.6
-
88
-
-
0023779791
-
Ras oncogene mediated induction of a 92 kDa metalloproteinase: Strong correlation with the malignant phenotype
-
88 Ballin M., Gomez D. E., Sinha C. C. and Thorgeirsson U. P. (1988) Ras oncogene mediated induction of a 92 kDa metalloproteinase: strong correlation with the malignant phenotype. Biochem. Biophys. Res. Commun. 154: 832-838
-
(1988)
Biochem. Biophys. Res. Commun.
, vol.154
, pp. 832-838
-
-
Ballin, M.1
Gomez, D.E.2
Sinha, C.C.3
Thorgeirsson, U.P.4
-
89
-
-
0030978840
-
Transcriptional activation of the matrix metalloproteinase-9 gene in an H-ras and v-myc transformed rat embryo cell line
-
89 Himelstein B. P., Lee E. J., Sato H., Seiki M. and Muschel R. J. (1997) Transcriptional activation of the matrix metalloproteinase-9 gene in an H-ras and v-myc transformed rat embryo cell line. Oncogene 14: 1995-1998
-
(1997)
Oncogene
, vol.14
, pp. 1995-1998
-
-
Himelstein, B.P.1
Lee, E.J.2
Sato, H.3
Seiki, M.4
Muschel, R.J.5
-
90
-
-
0028950493
-
The effect of E1A transfection on MMP-9 expression and metastatic potential
-
90 Bernhard E. J., Hagner B., Wong C., Lubenski I. and Muschel R. J. (1995) The effect of E1A transfection on MMP-9 expression and metastatic potential. Int. J. Cancer 60: 718-724
-
(1995)
Int. J. Cancer
, vol.60
, pp. 718-724
-
-
Bernhard, E.J.1
Hagner, B.2
Wong, C.3
Lubenski, I.4
Muschel, R.J.5
-
91
-
-
0027344507
-
Ras-responsive genes and tumor metastasis
-
91 Chambers A. and Tuck A. (1993) Ras-responsive genes and tumor metastasis. Crit. Rev. Oncog. 4: 95-114
-
(1993)
Crit. Rev. Oncog.
, vol.4
, pp. 95-114
-
-
Chambers, A.1
Tuck, A.2
-
92
-
-
0028957571
-
Role of phospholipase D in laminin-induced production of gelatinasc A (MMP-2) in metastatic cells
-
92 Reich R., Blumenthal M. and Liscovitch M. (1995) Role of phospholipase D in laminin-induced production of gelatinasc A (MMP-2) in metastatic cells. Clin. E.xp. Metastasis 13: 134-140
-
(1995)
Clin. E.xp. Metastasis
, vol.13
, pp. 134-140
-
-
Reich, R.1
Blumenthal, M.2
Liscovitch, M.3
-
93
-
-
0029563161
-
Release of gelatinase A (matrix metalloproteinase 2) induced by photolysis of caged phosphatidic acid in HT 1080 metastatic fibrosarcoma cells
-
93 Williger B.-T., Reich R., Neeman M., Bercovici T. and Liscovitch M. (1995) Release of gelatinase A (matrix metalloproteinase 2) induced by photolysis of caged phosphatidic acid in HT 1080 metastatic fibrosarcoma cells. J. Biol. Chem. 270: 29656-29659
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 29656-29659
-
-
Williger, B.-T.1
Reich, R.2
Neeman, M.3
Bercovici, T.4
Liscovitch, M.5
-
94
-
-
0027372389
-
Neutrophil phospholipase D is activated by a membrane-associated Rho family small molecular weight GTP-binding protein
-
94 Bowman E. P., Uhlinger D. J. and Lambeth J. D. (1993) Neutrophil phospholipase D is activated by a membrane-associated Rho family small molecular weight GTP-binding protein. J. Biol. Chem. 268: 21509-21512
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 21509-21512
-
-
Bowman, E.P.1
Uhlinger, D.J.2
Lambeth, J.D.3
-
95
-
-
0027999909
-
Activation of rat liver phospholipase D by the small GTP-binding protein RhoA
-
95 Malcolm K. C., Ross A. H., Qiu R. G., Symons M. and Exton J. H. (1994) Activation of rat liver phospholipase D by the small GTP-binding protein RhoA. J. Biol. Chem. 269: 25951-25954
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 25951-25954
-
-
Malcolm, K.C.1
Ross, A.H.2
Qiu, R.G.3
Symons, M.4
Exton, J.H.5
-
96
-
-
0028326455
-
Activation of type D phospholipase by scrum stimulation and ras-induced transformation in NIH 3T3 cells
-
96 Carnero A., Cuadraro A., del Peso L. and Lacal J. C. (1994) Activation of type D phospholipase by scrum stimulation and ras-induced transformation in NIH 3T3 cells. Oncogene 9: 1387-1395
-
(1994)
Oncogene
, vol.9
, pp. 1387-1395
-
-
Carnero, A.1
Cuadraro, A.2
Del Peso, L.3
Lacal, J.C.4
-
97
-
-
0028921344
-
Ras mediates the activation of phospholipase D by v-Src
-
97 Jiang H., Lu Z., Luo J.-Q., Wolfman A. and Foster D. A. (1995) Ras mediates the activation of phospholipase D by v-Src. J. Biol. Chem. 270: 6006-6009
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 6006-6009
-
-
Jiang, H.1
Lu, Z.2
Luo, J.-Q.3
Wolfman, A.4
Foster, D.A.5
-
98
-
-
0031057917
-
Activation of phospholipase D by growth factors and oncogenes in murine fibroblast follow alternative but cross-talking pathways
-
98 Peso L. del, Lucas L., Esteve P. and Lacal J. C. (1997) Activation of phospholipase D by growth factors and oncogenes in murine fibroblast follow alternative but cross-talking pathways. Biochem. J. 322: 519-528
-
(1997)
Biochem. J.
, vol.322
, pp. 519-528
-
-
Del Peso, L.1
Lucas, L.2
Esteve, P.3
Lacal, J.C.4
-
99
-
-
0029943257
-
Activation of phospholipase D by Ras proteins is independent of protein kinase C
-
99 Peso L. del, Hernández R., Esteve P. and Lacal J. C. (1996) Activation of phospholipase D by Ras proteins is independent of protein kinase C. J. Cell. Biochem. 61: 599-608
-
(1996)
J. Cell. Biochem.
, vol.61
, pp. 599-608
-
-
Del Peso, L.1
Hernández, R.2
Esteve, P.3
Lacal, J.C.4
-
100
-
-
0029153402
-
Expression of matrix metalloproteinase matrilysin (MMP-7) was induced by activated Ki-ras via AP-1 activation in SW1417 colon cancer cells
-
100 Yamamoto H., Itoh F., Senota A., Adachi Y., Yoshimoto M., Endoh T. et al. (1995) Expression of matrix metalloproteinase matrilysin (MMP-7) was induced by activated Ki-ras via AP-1 activation in SW1417 colon cancer cells. J. Clin. Lab. Anal. 9: 297-301
-
(1995)
J. Clin. Lab. Anal.
, vol.9
, pp. 297-301
-
-
Yamamoto, H.1
Itoh, F.2
Senota, A.3
Adachi, Y.4
Yoshimoto, M.5
Endoh, T.6
-
101
-
-
0024539580
-
Induction of urokinase activity and malignant phenotype in bladder carcinoma cells after transfection of activated Ha-ras oncogene
-
101 Brunner G., Pohl J., Erkell L. J., Radler-Pohl A. and Schirrmacher V. (1989) Induction of urokinase activity and malignant phenotype in bladder carcinoma cells after transfection of activated Ha-ras oncogene. J. Cancer. Res. Clin. Oncol. 115: 139-144
-
(1989)
J. Cancer. Res. Clin. Oncol.
, vol.115
, pp. 139-144
-
-
Brunner, G.1
Pohl, J.2
Erkell, L.J.3
Radler-Pohl, A.4
Schirrmacher, V.5
-
102
-
-
0032485048
-
The plasminogen activator system in pancreas cancer: Role of t-PA in the invasive potential in vitro
-
102 Paciucci R., Tora M., Diaz V. M. and Real F. X. (1998) The plasminogen activator system in pancreas cancer: role of t-PA in the invasive potential in vitro. Oncogene 16: 625-633
-
(1998)
Oncogene
, vol.16
, pp. 625-633
-
-
Paciucci, R.1
Tora, M.2
Diaz, V.M.3
Real, F.X.4
-
103
-
-
0031041465
-
Characterization of downstream Ras signals that induce alternative protease-dependent invasive phenotypes
-
103 Silberman S., Janulis M. and Schultz R. M. (1997) Characterization of downstream Ras signals that induce alternative protease-dependent invasive phenotypes. J. Biol. Chem. 272: 5927-5935
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 5927-5935
-
-
Silberman, S.1
Janulis, M.2
Schultz, R.M.3
-
104
-
-
0026483206
-
Fibroblasts transformed by different ras oncogenes show dissimilar patterns of protease gene expression and regulation
-
104 Zhang J. Y. and Schultz R. M. (1992) Fibroblasts transformed by different ras oncogenes show dissimilar patterns of protease gene expression and regulation. Cancer Res. 52: 6682-6689
-
(1992)
Cancer Res.
, vol.52
, pp. 6682-6689
-
-
Zhang, J.Y.1
Schultz, R.M.2
-
105
-
-
0027246039
-
Defining the critical gene expression changes associated with expression and suppression of the lumorigenic and metastatic phenotype in Ha-ras-transformed rat embryo fibroblast cell
-
105 Su Z. Z., Austin V. N., Zimmer S. G. and Fisher P. B. (1993) Defining the critical gene expression changes associated with expression and suppression of the lumorigenic and metastatic phenotype in Ha-ras-transformed rat embryo fibroblast cell. Oncogene 8: 1211-1219
-
(1993)
Oncogene
, vol.8
, pp. 1211-1219
-
-
Su, Z.Z.1
Austin, V.N.2
Zimmer, S.G.3
Fisher, P.B.4
-
106
-
-
0026559860
-
Increased expression of cathepsins L and B and decreased activity of their inhibitors in metastatic, ras-transformed NTH 3T3 cells
-
106 Chambers A. F., Colella R., Denhardi D. T. and Wilson S. M. (1992) Increased expression of cathepsins L and B and decreased activity of their inhibitors in metastatic, ras-transformed NTH 3T3 cells. Mol. Carcinogenesis 5: 238-245
-
(1992)
Mol. Carcinogenesis
, vol.5
, pp. 238-245
-
-
Chambers, A.F.1
Colella, R.2
Denhardi, D.T.3
Wilson, S.M.4
-
107
-
-
0030447757
-
Up-regulation of vascular endothelial growth factor/vascular permeability factor in mouse skin carcinogenesis correlates with malignant progression state and activated H-ras expression levels
-
107 Larcher F., Robles A. I., Duran H., Murillas R., Quintanilla M., Cano A. et al. (1996) Up-regulation of vascular endothelial growth factor/vascular permeability factor in mouse skin carcinogenesis correlates with malignant progression state and activated H-ras expression levels. Cancer Res. 56: 5391-5396
-
(1996)
Cancer Res.
, vol.56
, pp. 5391-5396
-
-
Larcher, F.1
Robles, A.I.2
Duran, H.3
Murillas, R.4
Quintanilla, M.5
Cano, A.6
-
108
-
-
0023797049
-
Altered expression of NM23, a gene associated with low tumor metastatic potential, during adenovirus 2 Ela inhibition of experimental metastasis
-
108 Steeg P. S., Bevilacqua G., Pozzalti R., Liotia L. A. and Sobel M. E. (1988) Altered expression of NM23, a gene associated with low tumor metastatic potential, during adenovirus 2 Ela inhibition of experimental metastasis. Cancer Res. 48: 6550-6554
-
(1988)
Cancer Res.
, vol.48
, pp. 6550-6554
-
-
Steeg, P.S.1
Bevilacqua, G.2
Pozzalti, R.3
Liotia, L.A.4
Sobel, M.E.5
-
109
-
-
0023938096
-
The E1a gene of adenovirus type 2 reduces the metastatic potential of ras-transformed rat embryo cells
-
109 Pozzati R., McCormick M., Thompson M. A. and Khoury G. (1998) The E1a gene of adenovirus type 2 reduces the metastatic potential of ras-transformed rat embryo cells. Mol. Cell. Biol. 8: 2984-2988
-
(1998)
Mol. Cell. Biol.
, vol.8
, pp. 2984-2988
-
-
Pozzati, R.1
McCormick, M.2
Thompson, M.A.3
Khoury, G.4
-
110
-
-
0023109730
-
Secretion of type IV collagenolytic protease and metastatic phenotype: Induction by transfection with c-Ha-ras but not c-Ha-ras plus Ad2-E1a
-
110 Garbisa S., Pozzati R., Muschel R. J., Saffiotti U., Ballin M., Goldfarb R. H. et al. (1987) Secretion of type IV collagenolytic protease and metastatic phenotype: induction by transfection with c-Ha-ras but not c-Ha-ras plus Ad2-E1a. Cancer Res. 47: 1523-1528
-
(1987)
Cancer Res.
, vol.47
, pp. 1523-1528
-
-
Garbisa, S.1
Pozzati, R.2
Muschel, R.J.3
Saffiotti, U.4
Ballin, M.5
Goldfarb, R.H.6
-
111
-
-
0032031062
-
Both focal adhesion kinase and c-Ras are required for the enhanced matrix metalloproteinase 9 secretion by fibronectin in ovarian cancer cells
-
111 Shibata K., Kikkawa F., Nawa A., Thant A. A., Naruse K., Mizutani S. et al. (1998) Both focal adhesion kinase and c-Ras are required for the enhanced matrix metalloproteinase 9 secretion by fibronectin in ovarian cancer cells. Cancer Res. 58: 900-903
-
(1998)
Cancer Res.
, vol.58
, pp. 900-903
-
-
Shibata, K.1
Kikkawa, F.2
Nawa, A.3
Thant, A.A.4
Naruse, K.5
Mizutani, S.6
-
112
-
-
0026504147
-
Social controls on cell survival and cell death
-
112 Raff M. C. (1992) Social controls on cell survival and cell death. Nature 356: 397-400
-
(1992)
Nature
, vol.356
, pp. 397-400
-
-
Raff, M.C.1
-
113
-
-
0027373764
-
Programmed cell death and control of cell survival: Lessons from nervous system
-
113 Raff M. C., Barres B. A.. Burne J. F., Coles H. S., Ishizaki Y. and Jacobson M. D. (1993) Programmed cell death and control of cell survival: lessons from nervous system. Science 262: 695-700
-
(1993)
Science
, vol.262
, pp. 695-700
-
-
Raff, M.C.1
Barres, B.A.2
Burne, J.F.3
Coles, H.S.4
Ishizaki, Y.5
Jacobson, M.D.6
-
114
-
-
0030947095
-
Programmed cell death in animal development
-
114 Jacobson D., Weil M. and Raff M. (1997) Programmed cell death in animal development. Cell 88: 347-354
-
(1997)
Cell
, vol.88
, pp. 347-354
-
-
Jacobson, D.1
Weil, M.2
Raff, M.3
-
115
-
-
0031046848
-
Apoptosis and disease: Regulation and clinical relevance of programmed cell death
-
115 Rudin C. M. and Thompson C. B. (1997) Apoptosis and disease: regulation and clinical relevance of programmed cell death. Annu. Rev. Med. 48: 267-281
-
(1997)
Annu. Rev. Med.
, vol.48
, pp. 267-281
-
-
Rudin, C.M.1
Thompson, C.B.2
-
116
-
-
0028329172
-
Apoptosis: Its significance in cancer and cancer therapy
-
116 Kerr J. F., Winterford C. M. and Harmon B. V. (1994) Apoptosis: its significance in cancer and cancer therapy. Cancer 73: 2013-2026
-
(1994)
Cancer
, vol.73
, pp. 2013-2026
-
-
Kerr, J.F.1
Winterford, C.M.2
Harmon, B.V.3
-
117
-
-
0021679848
-
Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation
-
117 Tsujimoto Y., Finger L. R., Yunis J., Nowell P. C. and Croce C. M. (1984) Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation. Science 226: 1097-1099
-
(1984)
Science
, vol.226
, pp. 1097-1099
-
-
Tsujimoto, Y.1
Finger, L.R.2
Yunis, J.3
Nowell, P.C.4
Croce, C.M.5
-
118
-
-
0022971142
-
Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/ immunoglobulin transcript resulting from the t(14;18) translocation
-
118 Cleary M. L., Smith S. D. and Sklar J. (1986) Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/ immunoglobulin transcript resulting from the t(14;18) translocation. Cell 47: 19-28
-
(1986)
Cell
, vol.47
, pp. 19-28
-
-
Cleary, M.L.1
Smith, S.D.2
Sklar, J.3
-
119
-
-
0021934042
-
Cloning the chromosomal breakpoint of t(14;18) human lymphomas: Clustering around JH on chromosome 14 and near a transcriptional unit on 18
-
119 Bakhshi A., Jensen J. P., Goldman P., Wright J. J., McBride O. W., Epstein A. L. et al. (1985) Cloning the chromosomal breakpoint of t(14;18) human lymphomas: clustering around JH on chromosome 14 and near a transcriptional unit on 18. Cell 41: 899-906
-
(1985)
Cell
, vol.41
, pp. 899-906
-
-
Bakhshi, A.1
Jensen, J.P.2
Goldman, P.3
Wright, J.J.4
McBride, O.W.5
Epstein, A.L.6
-
120
-
-
0028335948
-
Anchorage dependence, integrins, and apoplosis
-
120 Ruoslahti E. and Reed J. C. (1994) Anchorage dependence, integrins, and apoplosis. Cell 77: 477-478
-
(1994)
Cell
, vol.77
, pp. 477-478
-
-
Ruoslahti, E.1
Reed, J.C.2
-
121
-
-
0028057613
-
Disruption of epithelial cell-matrix interactions induces apoptosis
-
121 Frisch S. M. and Francis H. (1994) Disruption of epithelial cell-matrix interactions induces apoptosis. J. Cell Biol. 124: 619-626
-
(1994)
J. Cell Biol.
, vol.124
, pp. 619-626
-
-
Frisch, S.M.1
Francis, H.2
-
122
-
-
0027451706
-
The extracellular matrix as a cell survival factor
-
122 Meredith J. E., Fazeli B. and Schwartz M. A. (1993) The extracellular matrix as a cell survival factor. Mol. Biol. Cell 4: 953-961
-
(1993)
Mol. Biol. Cell
, vol.4
, pp. 953-961
-
-
Meredith, J.E.1
Fazeli, B.2
Schwartz, M.A.3
-
123
-
-
0030913673
-
Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway
-
123 Khwaja A., Rodriguez-Viciana P., Wennstrom S., Warne P. H. and Downward J. (1997) Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway. EMBO J. 16: 2783-2793
-
(1997)
EMBO J.
, vol.16
, pp. 2783-2793
-
-
Khwaja, A.1
Rodriguez-Viciana, P.2
Wennstrom, S.3
Warne, P.H.4
Downward, J.5
-
124
-
-
0032575705
-
A matter of life and cell death
-
124 Evan G. and Littlewood T. (1998) A matter of life and cell death. Science 281: 1317-1322
-
(1998)
Science
, vol.281
, pp. 1317-1322
-
-
Evan, G.1
Littlewood, T.2
-
125
-
-
0026642195
-
Induction of apoplosis in fibroblasts by c-myc protein
-
125 Evan G. I., Wyllie A. H., Gilbert C. S., Littlewood T. D., Land H., Brooks M. et al. ( 1992) Induction of apoplosis in fibroblasts by c-myc protein. Cell 69: 119-128
-
(1992)
Cell
, vol.69
, pp. 119-128
-
-
Evan, G.I.1
Wyllie, A.H.2
Gilbert, C.S.3
Littlewood, T.D.4
Land, H.5
Brooks, M.6
-
126
-
-
0026667219
-
Role for c-myc in activation-induced apoptolic cell death in T cell hybridomus
-
126 Shi Y., Glynn J. M., Guilbert L. J., Cotter T. G., Bissonnette R. P. and Green D. R. (1992) Role for c-myc in activation-induced apoptolic cell death in T cell hybridomus. Science 257: 212-214
-
(1992)
Science
, vol.257
, pp. 212-214
-
-
Shi, Y.1
Glynn, J.M.2
Guilbert, L.J.3
Cotter, T.G.4
Bissonnette, R.P.5
Green, D.R.6
-
127
-
-
0031028730
-
Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB
-
127 Kauffmann-Zeh A., Rodriguez-Viciana P., Ulrich E., Gilbert C., Coffer P., Downward J. et al. (I997) Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB. Nature 385: 544-548
-
(1997)
Nature
, vol.385
, pp. 544-548
-
-
Kauffmann-Zeh, A.1
Rodriguez-Viciana, P.2
Ulrich, E.3
Gilbert, C.4
Coffer, P.5
Downward, J.6
-
128
-
-
0030998763
-
Role of oncogenes in resistance and killing by cancer therapeutic agents
-
128 el-Deiry W.S. (1997) Role of oncogenes in resistance and killing by cancer therapeutic agents. Curr. Opin. Oncol. 9: 79-87
-
(1997)
Curr. Opin. Oncol.
, vol.9
, pp. 79-87
-
-
El-Deiry, W.S.1
-
129
-
-
0028910190
-
Induction of apoptosis in NIH 3T3 cells by rho-p21, a GTPase protein of the ras superfamily
-
129 Jiménez B., Arends M., Esteve P., Perona R., Sánchez R., Ramón y Cajal S. et al. (1995) Induction of apoptosis in NIH 3T3 cells by rho-p21, a GTPase protein of the ras superfamily. Oncogcne 10: 811-816
-
(1995)
Oncogcne
, vol.10
, pp. 811-816
-
-
Jiménez, B.1
Arends, M.2
Esteve, P.3
Perona, R.4
Sánchez, R.5
Ramón Y Cajal, S.6
-
130
-
-
0029610156
-
Induction of apoptosis by rho in NIH 3T3 cells requires competence and progression signals: Ceramides function as a progression factor for apoptosis
-
130 Esteve P., del Peso L. and Lacal J. C. (1995) Induction of apoptosis by rho in NIH 3T3 cells requires competence and progression signals: ceramides function as a progression factor for apoptosis. Oncogene 11: 2657-2665
-
(1995)
Oncogene
, vol.11
, pp. 2657-2665
-
-
Esteve, P.1
Del Peso, L.2
Lacal, J.C.3
-
131
-
-
0032497699
-
Rho-regulated signals induce apoplosis in vitro and in vivo by a p53-independent, but Bcl2-dependent pathway
-
131 Esteve P., Embade N., Perona R., Jiménez B., León J., Peso L. del et al. (1998) Rho-regulated signals induce apoplosis in vitro and in vivo by a p53-independent, but Bcl2-dependent pathway. Oncogene 17: 1855-1869
-
(1998)
Oncogene
, vol.17
, pp. 1855-1869
-
-
Esteve, P.1
Embade, N.2
Perona, R.3
Jiménez, B.4
León, J.5
Del Peso, L.6
-
132
-
-
0030790547
-
Regulation of proliferation and apoptosis by Ras and Rho GTPases through specific phospholipid-dependent signaling
-
132 Lacal J. C. (1997) Regulation of proliferation and apoptosis by Ras and Rho GTPases through specific phospholipid-dependent signaling. FEBS Lett. 410: 73-77
-
(1997)
FEBS Lett.
, vol.410
, pp. 73-77
-
-
Lacal, J.C.1
-
133
-
-
0028025563
-
Apoptosis in cancer therapy: Crossing the threshold
-
133 Fisher D. E. (1994) Apoptosis in cancer therapy: crossing the threshold. Cell 78: 539-542
-
(1994)
Cell
, vol.78
, pp. 539-542
-
-
Fisher, D.E.1
|