Activation of phospholipase D by ras proteins is independent of protein kinase C

Journal of Cellular Biochemistry

Volumn 61, Issue 4, 1996, Pages 599-608

  Del Peso, Luis ^a   Hernández, Rubén ^a   Esteve, Pilar ^a   Lacal, Juan Carlos ^a  

^a INSTITUTO DE INVESTIGACIONES BIOMÉDICAS ALBERTO SOLS   (Spain)

Author keywords

growth factors; phorbol esters; phospholipase D; PKC; ras proteins

Indexed keywords

FIBROBLAST GROWTH FACTOR; GROWTH FACTOR; PHORBOL ESTER; PHOSPHATIDYLCHOLINE; PHOSPHOLIPASE D; PLATELET DERIVED GROWTH FACTOR; PROTEIN KINASE C; RAS PROTEIN;

ANIMAL CELL; ARTICLE; CELL STRAIN 3T3; CELL TRANSFORMATION; CONTROLLED STUDY; ENZYME ACTIVATION; FETUS; MOUSE; NEWBORN; NONHUMAN; ONCOGENE RAS; ONCOGENE SRC; PRIORITY JOURNAL; RAT; SECOND MESSENGER;

3T3 CELLS; ANIMALS; CELL LINE, TRANSFORMED; CHOLINE; ENZYME ACTIVATION; ENZYME INHIBITORS; FIBROBLAST GROWTH FACTOR 2; GENES, RAS; GENES, SRC; INDOLES; MALEIMIDES; MICE; PHORBOL 12,13-DIBUTYRATE; PHOSPHOLIPASE D; PLATELET-DERIVED GROWTH FACTOR; PROTEIN KINASE C; RAS PROTEINS;

EID: 0029943257     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4644(19960616)61:4<599::AID-JCB14>3.0.CO;2-B     Document Type: Article

References (41)

1. Berridge MJ (1993): Inositol trisphosphate and calcium signalling. Nature 361:315-325.
2. Billah MM (1990): The regulation and cellular functions of phosphatidylcholine hydrolysis. Biochem J 269:281-291.
3. Bowman EP, Uhlinger DJ, Lambeth JD (1993): Neutrophil phospholipase D is activated by a membrane-associated Rho family small molecular weight GTP-binding protein. J Biol Chem 268:21509-21512.
4. Brown HA, Gutowski S, Moomaw CR, Slaughter C, Sternweis P (1993): ADP-ribosylation factor, a small GTP-dependent regulatory protein, stimulates phospholipase D activity. Cell 75:1137-1144.
5. Cantley LC, Auger KR, Carpenter C, Duckworth B, Graziani A, Kapeller R, Soltoff S (1991): Oncogenes and signal transduction. Cell 64:281-302.
6. ras and phospholipases: a comparative study. Mol Cell Biol 15:1094-1101.
7. Carnero A, Cuadrado A, del Peso L, Lacal JC (1994): Activation of a type D phospholipase by serum stimulation and ras-induced transformation in NIH3T3 cells. Oncogene 9:1387-1395.
8. Cook SJ, Wakelam MJO (1992): Epidermal growth factor increases sn-1,2-diacylglycerol levels and activates phospholipase D-catalysed phosphatidylcholine breakdown in Swiss 3T3 cells in the absence of inositol-lipid hydrolysis. Biochem J 285:247-253.
9. 2+-independent secretion and phospholipase D activity in permeabilized human platelets. FEBS Lett 316:170-174.
10. Divecha N, Irvine RF (1995): Phospholipid signaling. Cell 80:269-278.
11. Eldar H, Ben-Av P, Schmidt US, Liuneh E, Liscovitch M (1993): Up-regulation of phospholipase D activity induced by overexpression of protein kinase Ca. J Biol Chem 268:12560-12564.
12. Exton JH (1994): Phosphatidylcholine breakdown and signal transduction. Biochim Biophys Acta 1212:26-42.
13. 1 receptors coupled to phospholipase D activation. Biochem J 304:543-548.
14. Fu T, Okano Y, Nozawa Y (1992): Differential pathways (phospholiopase C and phospholipase D) of bradykinin-induced biphasic 1,2-diacylglycerol formation in non-transformed and K-ras-transformed NIH-3T3 fibroblasts. Biochem J 283:347-354.
15. Geny B, Cockcroft S (1992): Synergistic activation of phospholipase D by protein kinase C- and G-protein-mediated pathways in streptolysin o-permeabilized HL-60 cells. Biochem J 284:531-538.
16. Gupta SK, Gallego C, Johnson GL, Heasley LE (1992): MAP kinase is constitutively activated in gip2 and src transformed Rat 1a fibroblast. J Biol Chem 267:7987-7990.
17. Huang C, Cabot MC (1990): Phorbol diesters stimulate the accumulation of phosphatidate, phosphatidylethanol, and diacylglycerol in three cell types. J Biol Chem 265:14858-14863.
18. Irving HR, Exton JH (1987): Phosphatidylcholine breakdown in rat liver plasma membranes. J Biol Chem 262: 3440-3443.
19. Jiang H, Alexandropoulos K, Song J, Foster DA (1994): Evidence that v-src-induced phospholipase D activity is mediated by a G-protein. Mol Cell Biol 14:3676-3682.
20. Jiang H, Lu Z, Luo J-Q, Wolfman A, Foster DA (1995): Ras mediates the activation of phospholipase D by v-Src. J Biol Chem 270:6006-6009.
21. Jiménez B, del Peso L, Montaner S, Esteve P, Lacal JC (1995): Generation of phosphorylcholine as an essential event in the activation of Raf-1 and MAP-kinases in growth factors-induced mitogenic stimulation. J Cell Biochem 57:141-149.
22. Kiss Z (1992): Differential effects of platelet-derived growth factor, serum and bombesin on phospholipase D-mediated hydrolysis of phosphatidylethanolamine in NIH3T3 fibro-blast. Biochem J 229-233.
23. Lacal JC, Carnero A (1994): Regulation of Ras proteins and their involvement in signal transduction pathways. (Review.) Oncol Rep 1:677-693.
24. Lacal JC, Moscat J, Aaronson SA (1987): Novel source of 1,2-diacylglycerol elevated in cells transformed by Ha-ras oncogene. Nature 330:269-272.
25. Lacal JC, Cuadrado A, Jones JE, Trotta R, Burstein DE, Thomson T, Pellicer A (1990): Regulation of protein kinase C activity in neuronal differentiation induced by the N-ras oncogene in PC-12 cells. Mol Cell Biol 10:2983-2990.
26. Leevers SJ, Marshall CJ (1992): Activation of extracellular signal-regulated kinase, ERK2, by p21 ras oncoprotein. EMBO J 11:569-574.
27. Leevers SJ, Paterson HF, Marshall CJ (1994): Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane. Nature 369:411-414.
28. Martinson EA, Trilivas I, Brown JH (1990): Rapid protein kinase C-dependent activation of phospholipase D leads to delayed 1,2-diglyceride accumulation. J Biol Chem 265: 22282-22287.
29. Nishizuka Y (1992): Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C. Science 258:607-614.
30. Olson SC, Bowman EP, Lamberth JD (1991): Phospholipase D activation in a cell-free System from human neutrophils by phorbol 12-myristate 13-acetate and guanosine 5′-o-(3-thiotriphosphate). J Biol Chem 266:17236-17242.
31. Plevin R, Cook SJ, Palmer S, Wakelan MJO (1991): Multiple sources of sn-1,2-diacylglycerol in platelet-derived-growth-factor-stimulated Swiss 3T3 fibroblasts. Biochem J 279: 559-565.
32. Quian Z, Drewes LR (1989): Muscarinic acetilcholine receptor regulates phosphatidylcholine phospholipase D in canine brain. J Biol Chem 264:21720-21724.
33. Reed JC, Yum S, Michael PC, Turner BC, Rapp UR (1991): Differential regulation of the p72-74 RAF-1 kinase in 3T3 fibroblasts expressing ras or src oncogenes. Cell Growth Diff 2:235-243.
34. Rodriguez-Viciana P, Warne PH, Dhand R, Vanhaesebroeck B, Gout I, Fry MJ, Waterfield MD, Downward J (1994): Phosphatidylinositol-3-OH kinase as a direct target of Ras. Nature 370:527-532.
35. Song J, Foster DA (1993): V-Src activates a unique phospholipase D activity that can be distinguished from the phospholipase D activity activated by phobol esters. Biochem J vol. 294 711-717.
36. Song J, Pfeffer LM, Foster DA(1991): v-Src increases diacylglycerol levels via a type D phospholipase-mediated hydrolysis of phosphatidylcholine. Mol Cell Biol 11:4903-4908.
37. Stokoe D, Macdonald SG, Cadwallader K, Symons M, Handcock JF (1994): Activation of Raf as result of recruitment to the plasma membrane. Science 264:1463-1466.
38. 2 lactoferrin release in adherent human neutrophils. J Biol Chem 269:8063-8068.
39. van Blitterswijk WJ, Schaap D, van der Bend RL (1994): Generation and Attenuation of lipid second mesengers in intracellular signalling. Curr Topics Membr 40:413-437.
40. van der Bend RI, de Widt J, van Corven EJ, Moolenaar WH, van Blitterswijk WJ (1992): The biologically active phospholipid, lysophosphatidic acid, induces phosphatidylcholine breakdown in fibroblasts via activation of phospholipase D. Biochem J 285:235-240.
41. van der Meulen J, Haslam RJ (1990): Phorbol ester treatment of intact rabbit platelets greatly enhances both the basal and guanosine 5′-[γ-thio]triphosphate-stimulated phospholipase D activities of isolated platelet membranes. Biochem J 271:693-700.