-
2
-
-
0028036918
-
Autoimmune disease: A problem of defective apoptosis
-
Mountz JD, Wu J, Cheng J, Zhou T. 1994. Autoimmune disease: a problem of defective apoptosis. Arthritis Rheum. 37:1415-20
-
(1994)
Arthritis Rheum.
, vol.37
, pp. 1415-1420
-
-
Mountz, J.D.1
Wu, J.2
Cheng, J.3
Zhou, T.4
-
3
-
-
0028240526
-
Programmed cell death: Implications for neuropsychiatric disorders
-
Margolis RL, Chuang D-M, Post RM. 1994. Programmed cell death: implications for neuropsychiatric disorders. Biol. Psychiatry 35:946-56
-
(1994)
Biol. Psychiatry
, vol.35
, pp. 946-956
-
-
Margolis, R.L.1
Chuang, D.-M.2
Post, R.M.3
-
5
-
-
0028025563
-
Apoptosis in cancer therapy: Crossing the threshold
-
Fisher DE. 1994. Apoptosis in cancer therapy: crossing the threshold. Cell 78:539-42
-
(1994)
Cell
, vol.78
, pp. 539-542
-
-
Fisher, D.E.1
-
7
-
-
0022546957
-
Analysis of the structure, transcription, and protein products of bcl-2, the gene involved in human follicular lymphoma
-
Tsujimoto Y, Croce CM. 1986. Analysis of the structure, transcription, and protein products of bcl-2, the gene involved in human follicular lymphoma. Proc. Natl. Acad. Sci USA 83:5214-18
-
(1986)
Proc. Natl. Acad. Sci USA
, vol.83
, pp. 5214-5218
-
-
Tsujimoto, Y.1
Croce, C.M.2
-
8
-
-
0027282044
-
Bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death
-
Boise LH, Gonzalez-Garcia M, Postema CE, et al. 1993. Bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death. Cell 74:597-608
-
(1993)
Cell
, vol.74
, pp. 597-608
-
-
Boise, L.H.1
Gonzalez-Garcia, M.2
Postema, C.E.3
-
9
-
-
0027480450
-
MCL1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to bcl-2
-
Kozopas KM, Yang T, Buchan HL, et al. 1993. MCL1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to bcl-2. Proc. Natl. Acad. Sci. USA 90:3516-20
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 3516-3520
-
-
Kozopas, K.M.1
Yang, T.2
Buchan, H.L.3
-
10
-
-
0027326012
-
Characterization of A1, a novel hematopoietic-specific early-response gene with sequence similarity to bcl-2
-
Lin EY, Orlofsky A, Berger MS, Prystowsky MB. 1993. Characterization of A1, a novel hematopoietic-specific early-response gene with sequence similarity to bcl-2. J. Immunol. 151:1979-88
-
(1993)
J. Immunol.
, vol.151
, pp. 1979-1988
-
-
Lin, E.Y.1
Orlofsky, A.2
Berger, M.S.3
Prystowsky, M.B.4
-
11
-
-
0027166048
-
Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
-
Oltvai ZN, Milliman CL, Korsmeyer SJ. 1993. Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 74:609-19
-
(1993)
Cell
, vol.74
, pp. 609-619
-
-
Oltvai, Z.N.1
Milliman, C.L.2
Korsmeyer, S.J.3
-
12
-
-
0028809209
-
L and Bcl-2, displaces Bax and promotes cell death
-
L and Bcl-2, displaces Bax and promotes cell death. Cell 80:285-91
-
(1995)
Cell
, vol.80
, pp. 285-291
-
-
Yang, E.1
Zha, J.2
Jockel, J.3
-
13
-
-
0028946015
-
Cloning of a bcl-2 homologue by interaction with adenovirus E1B 19K
-
Farrow SN, White JHM, Martinou I, et al. 1995. Cloning of a bcl-2 homologue by interaction with adenovirus E1B 19K. Nature 374:731-33
-
(1995)
Nature
, vol.374
, pp. 731-733
-
-
Farrow, S.N.1
White, J.H.M.2
Martinou, I.3
-
14
-
-
0028986876
-
Induction of apoptosis by the Bcl-2 homologue Bak
-
Chittenden T, Harrington EA, O'Connor R, et al. 1995. Induction of apoptosis by the Bcl-2 homologue Bak. Nature 374:733-36
-
(1995)
Nature
, vol.374
, pp. 733-736
-
-
Chittenden, T.1
Harrington, E.A.2
O'Connor, R.3
-
15
-
-
0028904163
-
Modulation of apoptosis by the widely distributed Bcl-2 homologue Bak
-
Kiefer MC, Brauer MJ, Powers VC, et al. 1995. Modulation of apoptosis by the widely distributed Bcl-2 homologue Bak. Nature 374:736-39
-
(1995)
Nature
, vol.374
, pp. 736-739
-
-
Kiefer, M.C.1
Brauer, M.J.2
Powers, V.C.3
-
16
-
-
0028017880
-
Interactions among members of the Bcl-2 protein family analyzed with a yeast two-hybrid system
-
Sato T, Hanada M, Bodrug S, et al. 1994. Interactions among members of the Bcl-2 protein family analyzed with a yeast two-hybrid system. Proc. Natl. Acad. Sci. USA 91:9238-42
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 9238-9242
-
-
Sato, T.1
Hanada, M.2
Bodrug, S.3
-
17
-
-
0029097470
-
Multiple Bcl-2 family members demonstrate competing dimerizations with Bax
-
Sedlak TW, Oltvai ZN, Yang E, et al. 1995. Multiple Bcl-2 family members demonstrate competing dimerizations with Bax. Proc. Natl Acad. Sci. USA 92:7834-38
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 7834-7838
-
-
Sedlak, T.W.1
Oltvai, Z.N.2
Yang, E.3
-
18
-
-
0028206341
-
BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heter-dimerization with Bax
-
Yin X-M, Oltvai ZN, Korsmeyer SJ. 1994. BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heter-dimerization with Bax. Nature 369:321-23
-
(1994)
Nature
, vol.369
, pp. 321-323
-
-
Yin, X.-M.1
Oltvai, Z.N.2
Korsmeyer, S.J.3
-
19
-
-
0028832667
-
A conserved domain in Bak, distinct from BH1 and BH2, mediates cell death and protein binding functions
-
Chittenden T, Flemington C, Houghton AB, et al. 1995. A conserved domain in Bak, distinct from BH1 and BH2, mediates cell death and protein binding functions. EMBO J. 14:5589-96
-
(1995)
EMBO J.
, vol.14
, pp. 5589-5596
-
-
Chittenden, T.1
Flemington, C.2
Houghton, A.B.3
-
20
-
-
0028812606
-
Bik, a novel death-inducing protein, shares a distinct sequence motif with Bcl-2 family proteins and interacts with viral and cellular survival-promoting proteins
-
Boyd JM, Gallo GJ, Elangovan B, et al. 1995. Bik, a novel death-inducing protein, shares a distinct sequence motif with Bcl-2 family proteins and interacts with viral and cellular survival-promoting proteins. Oncogene 11:1921-28
-
(1995)
Oncogene
, vol.11
, pp. 1921-1928
-
-
Boyd, J.M.1
Gallo, G.J.2
Elangovan, B.3
-
21
-
-
0026582702
-
C. elegans gene ced-9 protects from programmed cell death
-
Hengartner MO, Ellis RE, Horvitz HR. 1992. C. elegans gene ced-9 protects from programmed cell death. Nature 356:494-99
-
(1992)
Nature
, vol.356
, pp. 494-499
-
-
Hengartner, M.O.1
Ellis, R.E.2
Horvitz, H.R.3
-
22
-
-
0028288277
-
C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2
-
Hengartner MO, Horvitz HR. 1994. C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2. Cell 76:665-76
-
(1994)
Cell
, vol.76
, pp. 665-676
-
-
Hengartner, M.O.1
Horvitz, H.R.2
-
25
-
-
0027525104
-
The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme
-
Yuan J, Shaham S, Ledoux S, et al. 1993. The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme. Cell 75: 641-52
-
(1993)
Cell
, vol.75
, pp. 641-652
-
-
Yuan, J.1
Shaham, S.2
Ledoux, S.3
-
26
-
-
0030012008
-
Developing Caenorhabditis elegans neurons may contain both cell-death protective and killer activities
-
Shaham S, Horvitz HR. 1996. Developing Caenorhabditis elegans neurons may contain both cell-death protective and killer activities. Genes Dev. 10:578-91
-
(1996)
Genes Dev.
, vol.10
, pp. 578-591
-
-
Shaham, S.1
Horvitz, H.R.2
-
27
-
-
0029664296
-
ICE family proteases: Mediators of all apoptotic cell death?
-
Henkart PA. 1996. ICE family proteases: mediators of all apoptotic cell death? Immunity 4:195-201
-
(1996)
Immunity
, vol.4
, pp. 195-201
-
-
Henkart, P.A.1
-
28
-
-
0030044324
-
ICE-LAP3, a novel mammalian homologue of the Caenorhabditis elegans cell death protein Ced-3 is activated during Fas- and tumor necrosis factor-induced apoptosis
-
Duan H, Chinnaiyan AM, Hudson PL, et al. 1996. ICE-LAP3, a novel mammalian homologue of the Caenorhabditis elegans cell death protein Ced-3 is activated during Fas- and tumor necrosis factor-induced apoptosis. J. Biol. Chem. 271:1621-25
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 1621-1625
-
-
Duan, H.1
Chinnaiyan, A.M.2
Hudson, P.L.3
-
29
-
-
0028107827
-
Crystal structure of the cysteine protease interleukin-1 beta-converting enzyme: A (p20/p10)2 homodimer
-
Walker NP, Talanian RV, Brady KD, et al. 1995. Crystal structure of the cysteine protease interleukin-1 beta-converting enzyme: a (p20/p10)2 homodimer. Cell 78: 343-52
-
(1995)
Cell
, vol.78
, pp. 343-352
-
-
Walker, N.P.1
Talanian, R.V.2
Brady, K.D.3
-
30
-
-
0028949537
-
Cloning and expression of four novel isoforms of human interleukin-1 beta converting enzyme with different apoptotic activities
-
Alnemri ES, Fernandes-Alnemri T, Litwack G. 1995. Cloning and expression of four novel isoforms of human interleukin-1 beta converting enzyme with different apoptotic activities. J. Biol. Chem. 270: 4312-17
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 4312-4317
-
-
Alnemri, E.S.1
Fernandes-Alnemri, T.2
Litwack, G.3
-
31
-
-
0028168593
-
Ich-1, an Ice/ced-3-related gene, encodes both positive and negative regulators of programmed cell death
-
Wang L, Miura M, Bergeron L, et al. 1994. Ich-1, an Ice/ced-3-related gene, encodes both positive and negative regulators of programmed cell death. Cell 78:739-50
-
(1994)
Cell
, vol.78
, pp. 739-750
-
-
Wang, L.1
Miura, M.2
Bergeron, L.3
-
32
-
-
0029025549
-
Mch2, a new member of the apoptotic CED-3/ICE cysteine protease gene family
-
Fernandes-Alnemri T, Litwack G, Alnemri ES. 1995. Mch2, a new member of the apoptotic CED-3/ICE cysteine protease gene family. Cancer Res. 55:2737-42
-
(1995)
Cancer Res.
, vol.55
, pp. 2737-2742
-
-
Fernandes-Alnemri, T.1
Litwack, G.2
Alnemri, E.S.3
-
33
-
-
0028984948
-
Mice deficient in IL-1β-converting enzyme are defective in production of mature IL-1β and resistant to endotoxic shock
-
Li P, Allen H, Banerjee S, et al. 1995. Mice deficient in IL-1β-converting enzyme are defective in production of mature IL-1β and resistant to endotoxic shock. Cell 80: 401-11
-
(1995)
Cell
, vol.80
, pp. 401-411
-
-
Li, P.1
Allen, H.2
Banerjee, S.3
-
34
-
-
0028920863
-
Altered cytokine export and apoptosis in mice deficient in interleukin-1β converting enzyme
-
Kiuda K, Lippke JA, Ku G, et al. 1995. Altered cytokine export and apoptosis in mice deficient in interleukin-1β converting enzyme. Science 267:2000-3
-
(1995)
Science
, vol.267
, pp. 2000-2003
-
-
Kiuda, K.1
Lippke, J.A.2
Ku, G.3
-
35
-
-
0029068871
-
Identification and inhibition of the ICE/CED3 protease necessary for mammalian apoptosis
-
Nicholson DW, Ali A, Thornberry NA, et al. 1995. Identification and inhibition of the ICE/CED3 protease necessary for mammalian apoptosis. Nature 376:37-43
-
(1995)
Nature
, vol.376
, pp. 37-43
-
-
Nicholson, D.W.1
Ali, A.2
Thornberry, N.A.3
-
36
-
-
0028990125
-
Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase
-
Tewari M, Quan LT, O'Rourke K, et al. 1995. Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase. Cell 81: 801-9
-
(1995)
Cell
, vol.81
, pp. 801-809
-
-
Tewari, M.1
Quan, L.T.2
O'Rourke, K.3
-
37
-
-
0028102478
-
Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE
-
Lazebnik YA, Kaufmann SH, Disnoyers S, et al. 1994. Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE. Nature 371:346-47
-
(1994)
Nature
, vol.371
, pp. 346-347
-
-
Lazebnik, Y.A.1
Kaufmann, S.H.2
Disnoyers, S.3
-
38
-
-
0028922462
-
Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease
-
Wang Z-Q, Auer B, Stingl L, et al. 1995. Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease. Genes Dev. 9:509-20
-
(1995)
Genes Dev.
, vol.9
, pp. 509-520
-
-
Wang, Z.-Q.1
Auer, B.2
Stingl, L.3
-
39
-
-
0028087585
-
Tyrosine kinase activation provides an early and requisite signal for Fas-induced apoptosis
-
Eischen CM, Dick CJ, Leibson PJ. 1994. Tyrosine kinase activation provides an early and requisite signal for Fas-induced apoptosis. J. Immunol. 153:1947-54
-
(1994)
J. Immunol.
, vol.153
, pp. 1947-1954
-
-
Eischen, C.M.1
Dick, C.J.2
Leibson, P.J.3
-
40
-
-
0028268215
-
Programmed cell death and Bcl-2 protection in the absence of a nucleus
-
Jacobson MD, Burne JF, Raff MC. 1994. Programmed cell death and Bcl-2 protection in the absence of a nucleus. EMBO J. 13:1899-910
-
(1994)
EMBO J.
, vol.13
, pp. 1899-1910
-
-
Jacobson, M.D.1
Burne, J.F.2
Raff, M.C.3
-
41
-
-
0029900295
-
The tumor necrosis factor ligand and receptor families
-
Bazzoni F, Beutler B. 1996. The tumor necrosis factor ligand and receptor families. N. Engl. J. Med. 334:1717-25
-
(1996)
N. Engl. J. Med.
, vol.334
, pp. 1717-1725
-
-
Bazzoni, F.1
Beutler, B.2
-
42
-
-
0029026548
-
FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis
-
Chinnaiyan AM, O'Rourke K, Tewari M, Dixit VM. 1995. FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis. Cell 81:505-12
-
(1995)
Cell
, vol.81
, pp. 505-512
-
-
Chinnaiyan, A.M.1
O'Rourke, K.2
Tewari, M.3
Dixit, V.M.4
-
43
-
-
0029054725
-
RIP: A novel protein containing a death domain that interacts with Fas/Apo-1 (CD95) in yeast and causes cell death
-
Stanger BZ, Leder P, Lee T, et al. 1995. RIP: a novel protein containing a death domain that interacts with Fas/Apo-1 (CD95) in yeast and causes cell death. Cell 81:513-23
-
(1995)
Cell
, vol.81
, pp. 513-523
-
-
Stanger, B.Z.1
Leder, P.2
Lee, T.3
-
44
-
-
0029007855
-
The TNF receptor 1-associated protein TRADD signals cell death and NF-κB activation
-
Hsu H, Xiong J, Goeddel DV. 1995. The TNF receptor 1-associated protein TRADD signals cell death and NF-κB activation. Cell 81:495-504
-
(1995)
Cell
, vol.81
, pp. 495-504
-
-
Hsu, H.1
Xiong, J.2
Goeddel, D.V.3
-
45
-
-
0030032106
-
TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways
-
Hsu H, Shu H-B, Pan M-G, Goeddel DV. 1996. TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways. Cell 84:299-308
-
(1996)
Cell
, vol.84
, pp. 299-308
-
-
Hsu, H.1
Shu, H.-B.2
Pan, M.-G.3
Goeddel, D.V.4
-
46
-
-
0030011398
-
Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death
-
Boldin MP, Goncharov TM, Goltsev YV, Wallach D. 1996. Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death. Cell 85:803-15
-
(1996)
Cell
, vol.85
, pp. 803-815
-
-
Boldin, M.P.1
Goncharov, T.M.2
Goltsev, Y.V.3
Wallach, D.4
-
47
-
-
15844412409
-
FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/Apo-1) death-inducing signaling complex (DISC)
-
Muzio M, Chinnaiyan AM, Kischkel FC, et al. 1996. FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/Apo-1) death-inducing signaling complex (DISC). Cell 85: 817-27
-
(1996)
Cell
, vol.85
, pp. 817-827
-
-
Muzio, M.1
Chinnaiyan, A.M.2
Kischkel, F.C.3
-
48
-
-
0028964917
-
Fas-induced apoptosis is mediated via a ceramide-initiated Ras signaling pathway
-
Gulbins E, Bissonnette R, Mahboubi A, et al. 1995. Fas-induced apoptosis is mediated via a ceramide-initiated Ras signaling pathway. Immunity 2:341-51
-
(1995)
Immunity
, vol.2
, pp. 341-351
-
-
Gulbins, E.1
Bissonnette, R.2
Mahboubi, A.3
-
49
-
-
0347537940
-
Requirement for ceramide-initiated SAPK/ JNK signaling in stress-induced apoptosis
-
Nerheij M, Bose R, Lin XH, et al. 1996. Requirement for ceramide-initiated SAPK/ JNK signaling in stress-induced apoptosis. Nature 380:75-79
-
(1996)
Nature
, vol.380
, pp. 75-79
-
-
Nerheij, M.1
Bose, R.2
Lin, X.H.3
-
50
-
-
0030060075
-
Requirement of an ICE-like protease for induction of apoptosis and ceramide generation by REAPER
-
Pronk GJ, Ramer K, Amiri P, Williams LT. 1996. Requirement of an ICE-like protease for induction of apoptosis and ceramide generation by REAPER. Science 271:808-10
-
(1996)
Science
, vol.271
, pp. 808-810
-
-
Pronk, G.J.1
Ramer, K.2
Amiri, P.3
Williams, L.T.4
-
51
-
-
0028124428
-
A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor
-
Rothe M, Wong SC, Henzel WJ, Goeddel DV. 1994. A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor. Cell 78:681-92
-
(1994)
Cell
, vol.78
, pp. 681-692
-
-
Rothe, M.1
Wong, S.C.2
Henzel, W.J.3
Goeddel, D.V.4
-
52
-
-
0028878977
-
The Epstein-Barr virus transforming protein LMP1 engages signaling proteins for the tumor necrosis factor receptor family
-
Mosialos G, Birkenbach M, Yalamanchili R, et al. 1995. The Epstein-Barr virus transforming protein LMP1 engages signaling proteins for the tumor necrosis factor receptor family. Cell 80:389-99
-
(1995)
Cell
, vol.80
, pp. 389-399
-
-
Mosialos, G.1
Birkenbach, M.2
Yalamanchili, R.3
-
53
-
-
0028936733
-
Involvement of CRAF1, a relative of TRAF, in CD40 signaling
-
Chang G, Cleary AM, Ye Z, et al. 1995. Involvement of CRAF1, a relative of TRAF, in CD40 signaling. Science 267: 1494-98
-
(1995)
Science
, vol.267
, pp. 1494-1498
-
-
Chang, G.1
Cleary, A.M.2
Ye, Z.3
-
54
-
-
0027943499
-
A novel RING finger protein interacts with the cytoplasmic domain of CD40
-
Hu HM, O'Rourke K, Boguski MS, Dixit VM. 1994. A novel RING finger protein interacts with the cytoplasmic domain of CD40. J. Biol. Chem. 269:30069-72
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 30069-30072
-
-
Hu, H.M.1
O'Rourke, K.2
Boguski, M.S.3
Dixit, V.M.4
-
55
-
-
0028809176
-
A novel member of the TRAF family of putative signal transducing proteins binds to the cytoplasmic domain of CD40
-
Sato T, Irie S, Reed JC. 1995. A novel member of the TRAF family of putative signal transducing proteins binds to the cytoplasmic domain of CD40. FEBS Lett. 358:113-18
-
(1995)
FEBS Lett.
, vol.358
, pp. 113-118
-
-
Sato, T.1
Irie, S.2
Reed, J.C.3
-
56
-
-
0028856787
-
Presence of a new conserved domain in CART1, a novel member of the tumor necrosis factor receptor-associated protein family, which is expressed in breast carcinoma
-
Regnier CH, Tomasetto C, Moog-Lutz C, et al. 1995. Presence of a new conserved domain in CART1, a novel member of the tumor necrosis factor receptor-associated protein family, which is expressed in breast carcinoma. J. Biol. Chem. 270:25715-21
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 25715-25721
-
-
Regnier, C.H.1
Tomasetto, C.2
Moog-Lutz, C.3
-
57
-
-
15844369897
-
CD30 contains two binding sites with different specificities for members of the tumor necrosis factor receptor-associated factor family of signal transducing proteins
-
Gedrich RW, Gilfillan MC, Duckett CS, et al. 1996. CD30 contains two binding sites with different specificities for members of the tumor necrosis factor receptor-associated factor family of signal transducing proteins. J. Biol. Chem. 271:12852-58
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 12852-12858
-
-
Gedrich, R.W.1
Gilfillan, M.C.2
Duckett, C.S.3
-
58
-
-
0028978626
-
TRAF2-mediated activation of NFκB by TNF receptor 2 and CD40
-
Rothe M, Sarma V, Dixit VM, Goeddel DV. 1995. TRAF2-mediated activation of NFκB by TNF receptor 2 and CD40. Science 269:1424-27
-
(1995)
Science
, vol.269
, pp. 1424-1427
-
-
Rothe, M.1
Sarma, V.2
Dixit, V.M.3
Goeddel, D.V.4
-
59
-
-
0028113218
-
Adenovirus E1B 19 kDa and Bcl-2 proteins interact with a common set of cellular proteins
-
Boyd JM, Malstrom S, Subramanian T, et al. 1994. Adenovirus E1B 19 kDa and Bcl-2 proteins interact with a common set of cellular proteins. Cell 79:341-51
-
(1994)
Cell
, vol.79
, pp. 341-351
-
-
Boyd, J.M.1
Malstrom, S.2
Subramanian, T.3
-
60
-
-
0027260656
-
Epstein-Barr virus-coded BHRF1 protein, a viral homologue of Bcl-2, protects human B cells from programmed cell death
-
Henderson S, Huen D, Rowe M, et al. 1993. Epstein-Barr virus-coded BHRF1 protein, a viral homologue of Bcl-2, protects human B cells from programmed cell death. Proc. Natl. Acad. Sci. USA 90:8479-83
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 8479-8483
-
-
Henderson, S.1
Huen, D.2
Rowe, M.3
-
61
-
-
0027264124
-
An African swine fever virus gene with similarity to the proto-oncogen bcl-2 and the Epstein-Barr virus gene BHRF1
-
Nielan JG, Lu Z, Afonzo L, et al. 1993. An African swine fever virus gene with similarity to the proto-oncogen bcl-2 and the Epstein-Barr virus gene BHRF1. J. Virol. 67:4391-94
-
(1993)
J. Virol.
, vol.67
, pp. 4391-4394
-
-
Nielan, J.G.1
Lu, Z.2
Afonzo, L.3
-
62
-
-
0025772343
-
Induction of Bcl-2 expression by Epstein-Barr virus latent membrane protein 1 protects infected B cells from programmed cell death
-
Henderson S, Rowe M, Gregory C, et al. 1991. Induction of Bcl-2 expression by Epstein-Barr virus latent membrane protein 1 protects infected B cells from programmed cell death. Cell 65:1107-15
-
(1991)
Cell
, vol.65
, pp. 1107-1115
-
-
Henderson, S.1
Rowe, M.2
Gregory, C.3
-
63
-
-
0026728952
-
Viral inhibition of inflammation: Cowpox virus encodes an inhibitor of the interleukin-1β converting enzyme
-
Ray CA, Black RA, Kronheim SR, et al. 1992. Viral inhibition of inflammation: cowpox virus encodes an inhibitor of the interleukin-1β converting enzyme. Cell 69: 597-604
-
(1992)
Cell
, vol.69
, pp. 597-604
-
-
Ray, C.A.1
Black, R.A.2
Kronheim, S.R.3
-
64
-
-
0028817947
-
Inhibition of ICE family proteases by baculovirus antiapoptotic protein p35
-
Bump NJ, Hackett M, Hugunin M, et al. 1995. Inhibition of ICE family proteases by baculovirus antiapoptotic protein p35. Science 269:1885-88
-
(1995)
Science
, vol.269
, pp. 1885-1888
-
-
Bump, N.J.1
Hackett, M.2
Hugunin, M.3
-
65
-
-
0028896092
-
The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy
-
Roy N, Mahadevan MS, McLean M, et al. 1995. The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy. Cell 80:167-78
-
(1995)
Cell
, vol.80
, pp. 167-178
-
-
Roy, N.1
Mahadevan, M.S.2
McLean, M.3
-
66
-
-
0029595282
-
The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins
-
Rothe M, Pan M-G, Henzel WJ, et al. 1995. The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins. Cell 83: 1243-52
-
(1995)
Cell
, vol.83
, pp. 1243-1252
-
-
Rothe, M.1
Pan, M.-G.2
Henzel, W.J.3
-
67
-
-
15844425961
-
A conserved family of cellular genes related to the baculovirus iap gene and encoding apoptosis inhibitors
-
Duckett CS, Nava VE, Gedrich RW, et al. 1996. A conserved family of cellular genes related to the baculovirus iap gene and encoding apoptosis inhibitors. EMBO J. 15: 2685-94
-
(1996)
EMBO J.
, vol.15
, pp. 2685-2694
-
-
Duckett, C.S.1
Nava, V.E.2
Gedrich, R.W.3
-
68
-
-
13344278692
-
Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes
-
Liston P, Roy N, Tamai K, et al. 1996. Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes. Nature 379:349-53
-
(1996)
Nature
, vol.379
, pp. 349-353
-
-
Liston, P.1
Roy, N.2
Tamai, K.3
-
69
-
-
0029953942
-
Cloning and expression of apoptosis inhibitory protein homologs that function to inhibit apoptosis and/or bind tumor necrosis factor receptor-associated factors
-
Uren AG, Pakusch M, Hawkins CJ, et al. 1996. Cloning and expression of apoptosis inhibitory protein homologs that function to inhibit apoptosis and/or bind tumor necrosis factor receptor-associated factors. Proc. Natl. Acad. Sci. USA 93:4974-78
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 4974-4978
-
-
Uren, A.G.1
Pakusch, M.2
Hawkins, C.J.3
-
71
-
-
0027451668
-
P53-dependent apoptosis modulates the cytotoxicity of anticancer agents
-
Lowe SW, Ruley HE, Jacks T, Housman DE. 1993. P53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell 74:957-67
-
(1993)
Cell
, vol.74
, pp. 957-967
-
-
Lowe, S.W.1
Ruley, H.E.2
Jacks, T.3
Housman, D.E.4
-
72
-
-
0028169994
-
P53-dependent apoptosis suppresses tumor growth and progression in vivo
-
Symonds H, Krall L, Remington L, et al. 1994. P53-dependent apoptosis suppresses tumor growth and progression in vivo. Cell 78:703-11
-
(1994)
Cell
, vol.78
, pp. 703-711
-
-
Symonds, H.1
Krall, L.2
Remington, L.3
-
74
-
-
0026760426
-
Requirement for a functional Rb-1 gene in murine development
-
Clarke A, Maandag E, van Roon M, et al. 1992. Requirement for a functional Rb-1 gene in murine development. Nature 359: 328-30
-
(1992)
Nature
, vol.359
, pp. 328-330
-
-
Clarke, A.1
Maandag, E.2
Van Roon, M.3
-
75
-
-
0026744563
-
Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis
-
Lee EY-HP, Chang C-Y, Hu N, et al. 1992. Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis. Nature 359:288-94
-
(1992)
Nature
, vol.359
, pp. 288-294
-
-
Lee, E.Y.-H.P.1
Chang, C.-Y.2
Hu, N.3
-
76
-
-
0026702996
-
Effects of an Rb mutation in the mouse
-
Jacks T, Fazeli A, Schmitt E, et al. 1992. Effects of an Rb mutation in the mouse. Nature 359:295-300
-
(1992)
Nature
, vol.359
, pp. 295-300
-
-
Jacks, T.1
Fazeli, A.2
Schmitt, E.3
-
77
-
-
0029888359
-
Tumor induction and tissue atrophy in mice lacking E2F-1
-
Yamasaki L, Jacks T, Bronson R, et al. 1996. Tumor induction and tissue atrophy in mice lacking E2F-1. Cell 85:537-48
-
(1996)
Cell
, vol.85
, pp. 537-548
-
-
Yamasaki, L.1
Jacks, T.2
Bronson, R.3
-
78
-
-
0029949784
-
E2F-1 functions in mice to promote apoptosis and suppress proliferation
-
Field SJ, Tsai F-Y, Kuo F, et al. 1996. E2F-1 functions in mice to promote apoptosis and suppress proliferation. Cell 85:549-61
-
(1996)
Cell
, vol.85
, pp. 549-561
-
-
Field, S.J.1
Tsai, F.-Y.2
Kuo, F.3
-
79
-
-
0027489384
-
Clinical implications of the p53 tumor-suppressor gene
-
Harris CC, Hollstein M. 1993. Clinical implications of the p53 tumor-suppressor gene. N. Engl. J. Med. 329:1318-27
-
(1993)
N. Engl. J. Med.
, vol.329
, pp. 1318-1327
-
-
Harris, C.C.1
Hollstein, M.2
-
80
-
-
0027944206
-
P53 status and the efficacy of cancer therapy in vivo
-
Lowe SW, Bodis S, McClatchey A, et al. 1994. P53 status and the efficacy of cancer therapy in vivo. Science 266:807-10
-
(1994)
Science
, vol.266
, pp. 807-810
-
-
Lowe, S.W.1
Bodis, S.2
McClatchey, A.3
-
81
-
-
0026781986
-
Bcl-2 gene transfer increases relative resistance of S49.1 and WEHI7.2 lymphoid cells to cell death and DNA fragmentation induced by glucocorticoids and multiple chemotherapeutic drugs
-
Miyashita T, Reed JC. 1992. Bcl-2 gene transfer increases relative resistance of S49.1 and WEHI7.2 lymphoid cells to cell death and DNA fragmentation induced by glucocorticoids and multiple chemotherapeutic drugs. Cancer Res. 52:5407-11
-
(1992)
Cancer Res.
, vol.52
, pp. 5407-5411
-
-
Miyashita, T.1
Reed, J.C.2
-
82
-
-
0027389763
-
Bcl-2 oncoprotein blocks chemotherapy-induced apoptosis in a human leukemia cell line
-
Miyashita T, Reed JC. 1993. Bcl-2 oncoprotein blocks chemotherapy-induced apoptosis in a human leukemia cell line. Blood 81:151-57
-
(1993)
Blood
, vol.81
, pp. 151-157
-
-
Miyashita, T.1
Reed, J.C.2
-
83
-
-
0027196091
-
Constitutive expression of human bcl-2 modulates nitrogen mustard and camptothecin induced apoptosis
-
Walton MI, Whysong D, O'Connor PM, et al. 1993. Constitutive expression of human bcl-2 modulates nitrogen mustard and camptothecin induced apoptosis. Cancer Res. 53:1853-61
-
(1993)
Cancer Res.
, vol.53
, pp. 1853-1861
-
-
Walton, M.I.1
Whysong, D.2
O'Connor, P.M.3
-
84
-
-
0027279128
-
Bcl-2 modulation of apoptosis induced by anticancer drugs: Resistance to thymidylate stress is independent of classical resistance pathways
-
Fisher TC, Milner AE, Gregory CD, et al. 1993. Bcl-2 modulation of apoptosis induced by anticancer drugs: resistance to thymidylate stress is independent of classical resistance pathways. Cancer Res. 53: 3321-26
-
(1993)
Cancer Res.
, vol.53
, pp. 3321-3326
-
-
Fisher, T.C.1
Milner, A.E.2
Gregory, C.D.3
-
85
-
-
0028322065
-
Bcl-2 inhibits chemotherapy-induced apoptosis in neuroblastoma
-
Dole M, Nunez G, Merchant AK, et al. 1994. Bcl-2 inhibits chemotherapy-induced apoptosis in neuroblastoma. Cancer Res. 54:3253-59
-
(1994)
Cancer Res.
, vol.54
, pp. 3253-3259
-
-
Dole, M.1
Nunez, G.2
Merchant, A.K.3
-
86
-
-
0028987830
-
L by cytotoxic drug exposure confers resistance to ionizing radiation-induced internucleosomal DNA fragmentation
-
L by cytotoxic drug exposure confers resistance to ionizing radiation-induced internucleosomal DNA fragmentation. Cell Growth Differ. 6:363-70
-
(1995)
Cell Growth Differ.
, vol.6
, pp. 363-370
-
-
Datta, R.1
Manome, Y.2
Taneja, N.3
-
88
-
-
0027164144
-
High expression of Bcl-2 protein in acute myeloid leukemia cells is associated with poor response to chemotherapy
-
Campos L, Rouault JP, Sabido O, et al. 1993. High expression of Bcl-2 protein in acute myeloid leukemia cells is associated with poor response to chemotherapy. Blood 81:3091-96
-
(1993)
Blood
, vol.81
, pp. 3091-3096
-
-
Campos, L.1
Rouault, J.P.2
Sabido, O.3
-
89
-
-
8044251593
-
Expression of the bcl-x gene in primary human breast cancer: Association with high tumor grade and nodal metastases
-
Abstr.
-
Olopade OI, Adeyanju MO, Safa AR, et al. 1996. Expression of the bcl-x gene in primary human breast cancer: association with high tumor grade and nodal metastases. ASCO Proc. 15:162 (Abstr.)
-
(1996)
ASCO Proc.
, vol.15
, pp. 162
-
-
Olopade, O.I.1
Adeyanju, M.O.2
Safa, A.R.3
-
90
-
-
0345483911
-
Phase 1 bcl-2 antisense trial: Preliminary results
-
Abstr.
-
Webb A, Cunningham D, Cotter F, et al. 1996. Phase 1 bcl-2 antisense trial: preliminary results. Ann. Oncol. 7(3):32 (Abstr.)
-
(1996)
Ann. Oncol.
, vol.7
, Issue.3
, pp. 32
-
-
Webb, A.1
Cunningham, D.2
Cotter, F.3
-
91
-
-
0028215537
-
T cell deletion in high antigen dose therapy of autoimmune encephalomyelitis
-
Critchfield JM, Racke MK, Zuniga-Pflucker JC, et al. 1994. T cell deletion in high antigen dose therapy of autoimmune encephalomyelitis. Science 263:1139-43
-
(1994)
Science
, vol.263
, pp. 1139-1143
-
-
Critchfield, J.M.1
Racke, M.K.2
Zuniga-Pflucker, J.C.3
-
92
-
-
0023759046
-
Lymphocyte activation by HIV-1 envelope glycoprotein
-
Kornfield H, Cruikshank WW, Pyle SW, et al. 1988. Lymphocyte activation by HIV-1 envelope glycoprotein. Nature 335:445-48
-
(1988)
Nature
, vol.335
, pp. 445-448
-
-
Kornfield, H.1
Cruikshank, W.W.2
Pyle, S.W.3
-
93
-
-
0026784923
-
Crosslinking CD4 by human immunodeficiency virus gp 120 primes T cells for activation-induced apoptosis
-
Banda NK, Bernier J, Kurahara DK, et al. 1992. Crosslinking CD4 by human immunodeficiency virus gp 120 primes T cells for activation-induced apoptosis. J. Exp. Med. 176:1099-106
-
(1992)
J. Exp. Med.
, vol.176
, pp. 1099-1106
-
-
Banda, N.K.1
Bernier, J.2
Kurahara, D.K.3
-
94
-
-
0029062573
-
Induction of apoptosis in uninfected lymphocytes by HIV-1 Tat protein
-
Li CJ, Friedman DJ, Wang C, et al. 1995. Induction of apoptosis in uninfected lymphocytes by HIV-1 Tat protein. Science 268:429-31
-
(1995)
Science
, vol.268
, pp. 429-431
-
-
Li, C.J.1
Friedman, D.J.2
Wang, C.3
|