Increased generation of alternatively cleaved β-amyloid peptides in cells expressing mutants of the amyloid precursor protein defective in endocytosis

Journal of Neurochemistry

Volumn 74, Issue 3, 2000, Pages 1131-1139

  Cescato, Renzo ^a   Dumermuth, Eric ^b   Spiess, Martin ^b   Paganetti, Paolo A ^a,c  

^a UNIVERSITY OF BASEL   (Switzerland)

^b UNIVERSITY OF BASEL   (Switzerland)

^c NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Endocytosis; HEK 293 cells; Protein processing; Proteolysis; Amyloid precursor protein; Secretase

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; TYROSINE;

AMINO TERMINAL SEQUENCE; ARTICLE; CELL MEMBRANE; ENDOCYTOSIS; ENZYME ACTIVITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN PROCESSING;

EID: 0033953961     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2000.741131.x     Document Type: Article

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