메뉴 건너뛰기




Volumn 55, Issue 3, 2000, Pages 184-187

Design and synthesis of melatonin receptors agonists and antagonists

Author keywords

Agonists and antagonists; Design and synthesis; Melatonin receptors

Indexed keywords

MELATONIN; MELATONIN DERIVATIVE; MELATONIN RECEPTOR; MELATONIN RECEPTOR AGONIST; MELATONIN RECEPTOR ANTAGONIST; UNCLASSIFIED DRUG;

EID: 0033943333     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-827X(00)00017-3     Document Type: Article
Times cited : (6)

References (40)
  • 1
    • 0025758136 scopus 로고
    • Pineal melatonin: Cell biology of its synthesis and of its physiological interactions
    • Reiter R.J. Pineal melatonin: cell biology of its synthesis and of its physiological interactions. Endocr. Rev. 12:1991;151-180.
    • (1991) Endocr. Rev. , vol.12 , pp. 151-180
    • Reiter, R.J.1
  • 2
    • 0030983299 scopus 로고    scopus 로고
    • Treatment of circadian rhythm disorders
    • Arendt J., Deacon S. Treatment of circadian rhythm disorders. Melatonin Chronobiol. Int. 14:1997;185-204.
    • (1997) Melatonin Chronobiol. Int. , vol.14 , pp. 185-204
    • Arendt, J.1    Deacon, S.2
  • 7
    • 0030951234 scopus 로고    scopus 로고
    • Physiological melatonin inhibition of human breast cancer cell growth in vitro: Evidence for a glutathione-mediated pathway
    • Blask D.E., Wilson S.T., Zalatan F. Physiological melatonin inhibition of human breast cancer cell growth in vitro: evidence for a glutathione-mediated pathway. Cancer Res. 57:1997;1909-1914.
    • (1997) Cancer Res. , vol.57 , pp. 1909-1914
    • Blask, D.E.1    Wilson, S.T.2    Zalatan, F.3
  • 9
    • 0030880294 scopus 로고    scopus 로고
    • Melatonergic ligands: Pharmaceutical development and clinical applications
    • Takaki K.S., Mahle C.D., Watson A.J. Melatonergic ligands: pharmaceutical development and clinical applications. Curr. Pharm. Des. 3:1997;429-438.
    • (1997) Curr. Pharm. Des. , vol.3 , pp. 429-438
    • Takaki, K.S.1    Mahle, C.D.2    Watson, A.J.3
  • 11
    • 0028907243 scopus 로고
    • Melatonin receptors: Are there multiple subtypes?
    • Dubocovich M.L. Melatonin receptors: are there multiple subtypes? Trends Pharmacol. Sci. 16:1995;50-56.
    • (1995) Trends Pharmacol. Sci. , vol.16 , pp. 50-56
    • Dubocovich, M.L.1
  • 12
    • 0029972613 scopus 로고    scopus 로고
    • Melatonin receptors step into light: Cloning and classification subtypes
    • Reppert S.M., Weaver D.R., Godson C. Melatonin receptors step into light: cloning and classification subtypes. Trends Pharmacol. Sci. 17:1996;100-102.
    • (1996) Trends Pharmacol. Sci. , vol.17 , pp. 100-102
    • Reppert, S.M.1    Weaver, D.R.2    Godson, C.3
  • 13
    • 0028054749 scopus 로고
    • Melatonin receptors: Localization, molecular pharmacology and physiological significance
    • Morgan P.J., Barrett P., Howell H.E., Helliwell R. Melatonin receptors: localization, molecular pharmacology and physiological significance. Neurochem. Int. 24:1994;101-146.
    • (1994) Neurochem. Int. , vol.24 , pp. 101-146
    • Morgan, P.J.1    Barrett, P.2    Howell, H.E.3    Helliwell, R.4
  • 14
    • 0028306136 scopus 로고
    • Expression cloning of a high-affinity melatonin receptor from Xenopus dermal melanophores
    • Ebisawa T., Karne S., Lerner M.R., Reppert S.M. Expression cloning of a high-affinity melatonin receptor from Xenopus dermal melanophores. Proc. Natl. Acad. Sci. USA. 91:1994;6133-6137.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 6133-6137
    • Ebisawa, T.1    Karne, S.2    Lerner, M.R.3    Reppert, S.M.4
  • 15
    • 0028018966 scopus 로고
    • Cloning and characterization of a mammalian melatonin receptor that mediates reproductive and circadian responses
    • Reppert S.M., Weaver D.R., Ebisawa T. Cloning and characterization of a mammalian melatonin receptor that mediates reproductive and circadian responses. Neuron. 13:1994;1177-1185.
    • (1994) Neuron , vol.13 , pp. 1177-1185
    • Reppert, S.M.1    Weaver, D.R.2    Ebisawa, T.3
  • 20
    • 0027716547 scopus 로고
    • 2-Substituted 5-methoxy-N-acyltryptamines: Synthesis, binding affinity for the melatonin receptor, and evaluation of the biological activity
    • Spadoni G., Stankov B., Duranti A., Biella G., Lucini V., Salvatori A., Fraschini F. 2-Substituted 5-methoxy-N-acyltryptamines: synthesis, binding affinity for the melatonin receptor, and evaluation of the biological activity. J. Med. Chem. 36:1993;4069-4074.
    • (1993) J. Med. Chem. , vol.36 , pp. 4069-4074
    • Spadoni, G.1    Stankov, B.2    Duranti, A.3    Biella, G.4    Lucini, V.5    Salvatori, A.6    Fraschini, F.7
  • 24
    • 0028909154 scopus 로고
    • Structural requirements at the melatonin receptor
    • Sugden D., Chong N.W.S., Lewis D.F.V. Structural requirements at the melatonin receptor. Br. J. Pharmacol. 114:1995;618-623.
    • (1995) Br. J. Pharmacol. , vol.114 , pp. 618-623
    • Sugden, D.1    Chong, N.W.S.2    Lewis, D.F.V.3
  • 25
    • 0030201178 scopus 로고    scopus 로고
    • The high affinity melatonin binding site probed with conformationally restricted ligands - Part I. Pharmacophore and minireceptor models
    • Jansen J.M., Copinga S., Gruppen G., Molinari E.J., Dubocovich M.L., Grol C.J. The high affinity melatonin binding site probed with conformationally restricted ligands. - Part I. Pharmacophore and minireceptor models Bioorg. Med. Chem. 4:1996;1321-1332.
    • (1996) Bioorg. Med. Chem. , vol.4 , pp. 1321-1332
    • Jansen, J.M.1    Copinga, S.2    Gruppen, G.3    Molinari, E.J.4    Dubocovich, M.L.5    Grol, C.J.6
  • 26
    • 0030220790 scopus 로고    scopus 로고
    • The high affinity melatonin binding site probed with conformationally restricted ligands - Part II. Homology modeling of the receptor
    • Grol C.J., Jansen J.M. The high affinity melatonin binding site probed with conformationally restricted ligands. - Part II. Homology modeling of the receptor Bioorg. Med. Chem. 4:1996;1333-1339.
    • (1996) Bioorg. Med. Chem. , vol.4 , pp. 1333-1339
    • Grol, C.J.1    Jansen, J.M.2
  • 27
    • 0031052115 scopus 로고    scopus 로고
    • Three-dimensional quantitative structure-activity relationship of melatonin receptor ligands: A comparative molecular field analysis study
    • Sicsic S., Serraz I., Andrieux J., Brémont B., Mathé-Allainmat M., Poncet A., Shen S., Langlois M. Three-dimensional quantitative structure-activity relationship of melatonin receptor ligands: a comparative molecular field analysis study. J. Med. Chem. 40:1997;739-748.
    • (1997) J. Med. Chem. , vol.40 , pp. 739-748
    • Sicsic, S.1    Serraz, I.2    Andrieux, J.3    Brémont, B.4    Mathé-Allainmat, M.5    Poncet, A.6    Shen, S.7    Langlois, M.8
  • 29
    • 0021211945 scopus 로고
    • 3H]dopamine release from retina
    • 3H]dopamine release from retina. Eur. J. Pharmacol. 105:1984;193-194.
    • (1984) Eur. J. Pharmacol. , vol.105 , pp. 193-194
    • Dubocovich, M.L.1
  • 30
    • 0023783020 scopus 로고
    • Luzindole (N-0774): A novel melatonin receptor antagonist
    • Dubocovich M.L. Luzindole (N-0774): a novel melatonin receptor antagonist. J. Pharmacol. Exp. Ther. 246:1988;902-910.
    • (1988) J. Pharmacol. Exp. Ther. , vol.246 , pp. 902-910
    • Dubocovich, M.L.1
  • 31
    • 0028970287 scopus 로고
    • Mapping the melatonin receptor. Part 3. Design and synthesis of melatonin agonists and antagonists derived from 2-phenyltryptamines
    • Garratt P.J., Jones R., Tocher D.A., Sugden D. Mapping the melatonin receptor. Part 3. Design and synthesis of melatonin agonists and antagonists derived from 2-phenyltryptamines. J. Med. Chem. 38:1995;1132-1139.
    • (1995) J. Med. Chem. , vol.38 , pp. 1132-1139
    • Garratt, P.J.1    Jones, R.2    Tocher, D.A.3    Sugden, D.4
  • 33
    • 0029069336 scopus 로고
    • Melatonin analogues: From pharmacology to clinical application
    • Guardiola-Le Maitre B., Delagrange P. Melatonin analogues: from pharmacology to clinical application. Eur. J. Med. Chem. 30:1995;643s-651s.
    • (1995) Eur. J. Med. Chem. , vol.30
    • Guardiola-Le Maitre, B.1    Delagrange, P.2
  • 35
    • 0032510073 scopus 로고    scopus 로고
    • Mapping the melatonin receptor. Part 5. Melatonin agonists and antagonists derived from tetrahydrocyclopent[b]indoles, tetrahydrocarbazoles and hexahydrocyclohept[b]indoles
    • Davies D.J., Garratt P.J., Tocher D.A., Vonhoff S., Davies J., Teh M.C., Sugden D. Mapping the melatonin receptor. Part 5. Melatonin agonists and antagonists derived from tetrahydrocyclopent[b]indoles, tetrahydrocarbazoles and hexahydrocyclohept[b]indoles. J. Med. Chem. 41:1998;451-467.
    • (1998) J. Med. Chem. , vol.41 , pp. 451-467
    • Davies, D.J.1    Garratt, P.J.2    Tocher, D.A.3    Vonhoff, S.4    Davies, J.5    Teh, M.C.6    Sugden, D.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.