Conformationally restrained melatonin analogues: Synthesis, binding affinity for the melatonin receptor, evaluation of the biological activity, and molecular modeling study

Journal of Medicinal Chemistry

Volumn 40, Issue 13, 1997, Pages 1990-2002

  Spadoni, Gilberto ^a   Balsamini, Cesarino ^a   Diamantini, Giuseppe ^a   Di Giacomo, Barbara ^a   Tarzia, Giorgio ^a   Mor, Marco ^b   Plazzi, Pier Vincenzo ^b   Rivara, Silvia ^b   Lucini, Valeria ^c   Nonno, Romolo ^c   Pannacci, Marilou ^c   Fraschini, Franco ^c   Stankov, Bojidar Michaylov ^c  

^a UNIVERSITY OF URBINO   (Italy)

^b UNIVERSITY OF PARMA   (Italy)

^c UNIVERSITY OF MILAN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

FORSKOLIN; INDOLE; MELATONIN DERIVATIVE;

ARTICLE; BINDING AFFINITY; BINDING SITE; CIRCADIAN RHYTHM; DRUG POTENCY; HORMONE ACTION; IMMUNOSTIMULATION; PROTEIN CONFORMATION; RECEPTOR BINDING;

ANIMALS; BINDING, COMPETITIVE; CHICKENS; CYCLIC AMP; DRUG DESIGN; FORSKOLIN; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); MELATONIN; MODELS, MOLECULAR; QUAIL; RECEPTORS, CELL SURFACE; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, MELATONIN; SUPERIOR COLLICULUS;

EID: 7844223548     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm960651z     Document Type: Article

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