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Volumn 6, Issue 7, 2000, Pages 2921-2930

A polyphenolic fraction from grape seeds causes irreversible growth inhibition of breast carcinoma MDA-MB468 cells by inhibiting mitogen- activated protein kinases activation and inducing G1 arrest and differentiation

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE 4; DNA FRAGMENT; MITOGEN ACTIVATED PROTEIN KINASE; PLANT EXTRACT; POLY(ADENOSINE DIPHOSPHATE RIBOSE); PROCYANIDIN;

EID: 0033941122     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (93)

References (74)
  • 2
    • 0031772908 scopus 로고    scopus 로고
    • Cancer chemoprevention. Part 1: Retinoids and carotenoids and other classic antioxidants
    • Singh, D. K., and Lippman, S. M. Cancer chemoprevention. Part 1: retinoids and carotenoids and other classic antioxidants. Oncology, 12: 1643-1659, 1998.
    • (1998) Oncology , vol.12 , pp. 1643-1659
    • Singh, D.K.1    Lippman, S.M.2
  • 3
    • 0032428948 scopus 로고    scopus 로고
    • Cancer chemoprevention. Part 2: Hormones, nonclassic antioxidant natural agents, NSAIDs, and other agents
    • Singh, D. K., and Lippman, S. M. Cancer chemoprevention. Part 2: hormones, nonclassic antioxidant natural agents, NSAIDs, and other agents. Oncology, 12: 1787-1800, 1998.
    • (1998) Oncology , vol.12 , pp. 1787-1800
    • Singh, D.K.1    Lippman, S.M.2
  • 7
    • 0027527396 scopus 로고
    • Cancer chemoprevention: Principles and prospects
    • Lond.
    • Morse, M. A., and Stoner, G. D. Cancer chemoprevention: principles and prospects. Carcinogenesis (Lond.), 14: 1737-1746, 1993.
    • (1993) Carcinogenesis , vol.14 , pp. 1737-1746
    • Morse, M.A.1    Stoner, G.D.2
  • 8
    • 0031394511 scopus 로고    scopus 로고
    • New rodent models for studies of chemopreventive agents
    • Lipkin, M. New rodent models for studies of chemopreventive agents. J. Cell. Biochem. Suppl., 28-29: 144-147, 1997.
    • (1997) J. Cell. Biochem. Suppl. , vol.28-29 , pp. 144-147
    • Lipkin, M.1
  • 10
    • 0030881274 scopus 로고    scopus 로고
    • The clinical evaluation of cancer prevention agents
    • Goodman, G. E. The clinical evaluation of cancer prevention agents. Proc. Soc. Exp. Biol. Med., 216: 253-259, 1997.
    • (1997) Proc. Soc. Exp. Biol. Med. , vol.216 , pp. 253-259
    • Goodman, G.E.1
  • 11
    • 0031321801 scopus 로고    scopus 로고
    • Properties of intraepithelial neoplasia relevant to the development of cancer chemopreventive agents
    • Boone, C. W., Bacus, J. W., Bacus, J. V., Steele, V. E., and Kelloff, G. J. Properties of intraepithelial neoplasia relevant to the development of cancer chemopreventive agents. J. Cell. Biochem. Suppl., 28-29: 1-20, 1997.
    • (1997) J. Cell. Biochem. Suppl. , vol.28-29 , pp. 1-20
    • Boone, C.W.1    Bacus, J.W.2    Bacus, J.V.3    Steele, V.E.4    Kelloff, G.J.5
  • 12
    • 0000147542 scopus 로고    scopus 로고
    • Recent advances in chemoprevention of cancer
    • Washington DC
    • Hong, W. K., and Sporn, M. B. Recent advances in chemoprevention of cancer. Science (Washington DC), 278: 1073-1077, 1997.
    • (1997) Science , vol.278 , pp. 1073-1077
    • Hong, W.K.1    Sporn, M.B.2
  • 13
    • 0030875366 scopus 로고    scopus 로고
    • An overview of chemoprevention: Current status and future prospects
    • Wattenberg, L. W. An overview of chemoprevention: current status and future prospects. Proc. Soc. Exp. Biol. Med., 216: 133-141, 1997.
    • (1997) Proc. Soc. Exp. Biol. Med. , vol.216 , pp. 133-141
    • Wattenberg, L.W.1
  • 14
    • 0024437914 scopus 로고
    • Antioxidants and multistage carcinogenesis in mouse skin
    • Perchellet, J-P., and Perchellet, E. M. Antioxidants and multistage carcinogenesis in mouse skin. Free Radic. Biol. Med., 7: 377-408, 1989.
    • (1989) Free Radic. Biol. Med. , vol.7 , pp. 377-408
    • Perchellet, J.-P.1    Perchellet, E.M.2
  • 15
    • 0031607310 scopus 로고    scopus 로고
    • Natural antioxidants in chemoprevention
    • Dragsted, L. O. Natural antioxidants in chemoprevention. Arch. Toxicol. Suppl., 20: 209-226, 1998.
    • (1998) Arch. Toxicol. Suppl. , vol.20 , pp. 209-226
    • Dragsted, L.O.1
  • 17
    • 0024355849 scopus 로고
    • Prevention of cancer: Vegetables and plants
    • Hocman, G. Prevention of cancer: vegetables and plants. Comp. Biochem. Physiol. B, 93: 201-212, 1989.
    • (1989) Comp. Biochem. Physiol. B , vol.93 , pp. 201-212
    • Hocman, G.1
  • 18
    • 0030867430 scopus 로고    scopus 로고
    • Polyphenols as inhibitors of carcinogenesis
    • Yang, C. S., Lee, M. J., Chen, L., and Yang, G. Y. Polyphenols as inhibitors of carcinogenesis. Environ. Health Perspect., 105 (Suppl 4): 971-976, 1997.
    • (1997) Environ. Health Perspect. , vol.105 , Issue.4 SUPPL. , pp. 971-976
    • Yang, C.S.1    Lee, M.J.2    Chen, L.3    Yang, G.Y.4
  • 19
    • 0002036740 scopus 로고
    • Tannins and the qualities of wines
    • P. E. Laks and R. W. Hemingway (eds.), New York: Plenum Press
    • Singleton, V. L. Tannins and the qualities of wines. In: P. E. Laks and R. W. Hemingway (eds.), Plant Polyphenols, pp. 859-880. New York: Plenum Press, 1992.
    • (1992) Plant Polyphenols , pp. 859-880
    • Singleton, V.L.1
  • 20
    • 0026631129 scopus 로고
    • Inhibition of skin tumor promoter-caused induction of epidermal ornithine decarboxylase in SENCAR mice by polyphenolic fraction isolated from green tea and its individual epicatechin derivatives
    • Agarwal, R., Katiyar, S. K., Zaidi, S. I. A., and Mukhtar, H. Inhibition of skin tumor promoter-caused induction of epidermal ornithine decarboxylase in SENCAR mice by polyphenolic fraction isolated from green tea and its individual epicatechin derivatives. Cancer Res., 52: 3582-3588, 1992.
    • (1992) Cancer Res. , vol.52 , pp. 3582-3588
    • Agarwal, R.1    Katiyar, S.K.2    Zaidi, S.I.A.3    Mukhtar, H.4
  • 21
  • 23
    • 0344188829 scopus 로고    scopus 로고
    • Procyanidines from Vitis vinifera seeds protect rabbit heart from ischemia/reperfusion injury: Antioxidant intervention and/or iron and copper sequestering ability
    • Maffei Facino, R., Carini, M., Aldini, G., Berti, F., Rossoni, G., Bombardelli, E., and Morazzoni, P. Procyanidines from Vitis vinifera seeds protect rabbit heart from ischemia/reperfusion injury: antioxidant intervention and/or iron and copper sequestering ability. Planta Med., 62: 495-502, 1996.
    • (1996) Planta Med. , vol.62 , pp. 495-502
    • Maffei Facino, R.1    Carini, M.2    Aldini, G.3    Berti, F.4    Rossoni, G.5    Bombardelli, E.6    Morazzoni, P.7
  • 24
    • 0345215163 scopus 로고    scopus 로고
    • Protective effects of grape seed proanthocyanidins and selected antioxidants against TPA-induced hepatic and brain lipid peroxidation and DNA fragmentation, and peritoneal macrophage activation in mice
    • Bagchi, D., Garg, A., Krohn, R. L., Bagchi, M., Bagchi, D. J., Balmoori, J., and Stohs, S. J. Protective effects of grape seed proanthocyanidins and selected antioxidants against TPA-induced hepatic and brain lipid peroxidation and DNA fragmentation, and peritoneal macrophage activation in mice. Gen. Pharmacol., 30: 771-776, 1998.
    • (1998) Gen. Pharmacol. , vol.30 , pp. 771-776
    • Bagchi, D.1    Garg, A.2    Krohn, R.L.3    Bagchi, M.4    Bagchi, D.J.5    Balmoori, J.6    Stohs, S.J.7
  • 25
    • 0031721688 scopus 로고    scopus 로고
    • Red-wine polyphenols and inhibition of platelet aggregation: Possible mechanisms, and potential use in health promotion and disease prevention
    • Halpern, M. J., Dahlgren, A. L., Laakso, I., Seppanen-Laakso, T., Dahlgren, J., and McAnulty, P. A. Red-wine polyphenols and inhibition of platelet aggregation: possible mechanisms, and potential use in health promotion and disease prevention. J. Int. Med. Res., 26: 171-180, 1998.
    • (1998) J. Int. Med. Res. , vol.26 , pp. 171-180
    • Halpern, M.J.1    Dahlgren, A.L.2    Laakso, I.3    Seppanen-Laakso, T.4    Dahlgren, J.5    McAnulty, P.A.6
  • 26
    • 0030760030 scopus 로고    scopus 로고
    • Wine as a biological fluid: History, production, and role in disease prevention
    • Soleas, G. J., Diamandis, E. P., and Goldberg, D. M. Wine as a biological fluid: history, production, and role in disease prevention. J. Clin. Lab. Anal., 11, 287-313, 1997.
    • (1997) J. Clin. Lab. Anal. , vol.11 , pp. 287-313
    • Soleas, G.J.1    Diamandis, E.P.2    Goldberg, D.M.3
  • 28
    • 0032991077 scopus 로고    scopus 로고
    • Inhibition of TPA-induced tumor promotion in CD-1 mouse epidermis by a polyphenolic fraction from grape seeds
    • Bomser, J. A., Singletary, K. W., Wallig, M. A., and Smith, M. A. L. Inhibition of TPA-induced tumor promotion in CD-1 mouse epidermis by a polyphenolic fraction from grape seeds. Cancer Lett., 135: 151-157, 1999.
    • (1999) Cancer Lett. , vol.135 , pp. 151-157
    • Bomser, J.A.1    Singletary, K.W.2    Wallig, M.A.3    Smith, M.A.L.4
  • 29
    • 0032821619 scopus 로고    scopus 로고
    • Anti-tumor promoting activity of a polyphenolic fraction isolated from grape seeds in mouse skin two-stage initiation-promotion protocol, and identification of procyanidin B5-3′-gallate as the most effective antioxidant constituent
    • Lond.
    • Zhao, J., Wang, J., Chen, Y., and Agarwal, R. Anti-tumor promoting activity of a polyphenolic fraction isolated from grape seeds in mouse skin two-stage initiation-promotion protocol, and identification of procyanidin B5-3′-gallate as the most effective antioxidant constituent. Carcinogenesis (Lond.), 20: 1737-1745, 1999.
    • (1999) Carcinogenesis , vol.20 , pp. 1737-1745
    • Zhao, J.1    Wang, J.2    Chen, Y.3    Agarwal, R.4
  • 30
    • 0027407231 scopus 로고
    • A case-control study of oral cancer in Beijing, People's Republic of China. Associations with nutrient intakes, foods and food groups
    • Zheng, T., Boyle, P., Willett, W. C., Hu, H., Dan, J., Evstifeeva, T. V., Niu, S., and MacMahon, B. A case-control study of oral cancer in Beijing, People's Republic of China. Associations with nutrient intakes, foods and food groups. Eur. J. Cancer B Oral Oncol., 29B: 45-55, 1993.
    • (1993) Eur. J. Cancer B Oral Oncol. , vol.29 B , pp. 45-55
    • Zheng, T.1    Boyle, P.2    Willett, W.C.3    Hu, H.4    Dan, J.5    Evstifeeva, T.V.6    Niu, S.7    MacMahon, B.8
  • 31
    • 15444344336 scopus 로고    scopus 로고
    • Intracellular coexpression of epidermal growth factor receptor, Her-2/neu, and p21ras in human breast cancers: Evidence for the existence of distinctive patterns of genetic evolution that are common to tumors from different patients
    • Shackney, S. E., Pollice, A. A., Smith, C. A., Janocko, L. E., Sweeney, L., Brown, K. A., Singh, S. G., Gu, L., Yakulis, R., and Lucke, J. F. Intracellular coexpression of epidermal growth factor receptor, Her-2/neu, and p21ras in human breast cancers: evidence for the existence of distinctive patterns of genetic evolution that are common to tumors from different patients. Clin. Cancer Res., 4: 913-928, 1998.
    • (1998) Clin. Cancer Res. , vol.4 , pp. 913-928
    • Shackney, S.E.1    Pollice, A.A.2    Smith, C.A.3    Janocko, L.E.4    Sweeney, L.5    Brown, K.A.6    Singh, S.G.7    Gu, L.8    Yakulis, R.9    Lucke, J.F.10
  • 32
    • 0029002907 scopus 로고
    • Aberrant function of the Ras signal pathway in human breast cancer
    • Clark, G. J., and Der, C. Aberrant function of the Ras signal pathway in human breast cancer. Breast Cancer Res. Treat., 35: 133-144, 1995.
    • (1995) Breast Cancer Res. Treat. , vol.35 , pp. 133-144
    • Clark, G.J.1    Der, C.2
  • 33
    • 0029928763 scopus 로고    scopus 로고
    • Signal transduction pathways induced by heregulin in MDA-MB-453 breast cancer cells
    • Sepp-Lorenzino, L., Eberhard, I., Ma, Z., Cho, C., Serve, H., Liu, F., Rosen, N., and Lupu, R. Signal transduction pathways induced by heregulin in MDA-MB-453 breast cancer cells. Oncogene, 12: 1679-1687, 1996.
    • (1996) Oncogene , vol.12 , pp. 1679-1687
    • Sepp-Lorenzino, L.1    Eberhard, I.2    Ma, Z.3    Cho, C.4    Serve, H.5    Liu, F.6    Rosen, N.7    Lupu, R.8
  • 34
    • 0025690737 scopus 로고
    • Heterodimerization of the erbB1 and erbB2 receptors in human breast carcinoma cells: A mechanism for receptor transregulation
    • Goldman, R., Levy, R. B., Peles, E., and Yarden, Y. Heterodimerization of the erbB1 and erbB2 receptors in human breast carcinoma cells: a mechanism for receptor transregulation. Biochemistry, 29: 11024-11028, 1990.
    • (1990) Biochemistry , vol.29 , pp. 11024-11028
    • Goldman, R.1    Levy, R.B.2    Peles, E.3    Yarden, Y.4
  • 35
    • 0032521210 scopus 로고    scopus 로고
    • Elevated insulin-like growth factor I receptor autophosphorylation and kinase activity in human breast cancer
    • Resnik, J. L., Reichart, D. B., Huey, K., Webster, N. J. G., and Seeley, B. L. Elevated insulin-like growth factor I receptor autophosphorylation and kinase activity in human breast cancer. Cancer Res., 58: 1159-1164, 1998.
    • (1998) Cancer Res. , vol.58 , pp. 1159-1164
    • Resnik, J.L.1    Reichart, D.B.2    Huey, K.3    Webster, N.J.G.4    Seeley, B.L.5
  • 36
    • 0029021518 scopus 로고
    • Heterodimerization and functional interaction between EGF receptor family member: A new signaling paradigm with implications for breast cancer research
    • Earp, H. S., Dawson, T. L., Li, H., and Yu, H. Heterodimerization and functional interaction between EGF receptor family member: a new signaling paradigm with implications for breast cancer research. Breast Cancer Res. Treat., 35: 115-132, 1995.
    • (1995) Breast Cancer Res. Treat. , vol.35 , pp. 115-132
    • Earp, H.S.1    Dawson, T.L.2    Li, H.3    Yu, H.4
  • 37
    • 0028968949 scopus 로고
    • Tyrosine kinase inhibition: An approach to drug development
    • Washington DC
    • Levitzki, A., and Gazit, A. Tyrosine kinase inhibition: an approach to drug development. Science (Washington DC), 267: 1782-1788, 1995.
    • (1995) Science , vol.267 , pp. 1782-1788
    • Levitzki, A.1    Gazit, A.2
  • 38
    • 0029758783 scopus 로고    scopus 로고
    • Redox modulation of tyrosine phosphorylation-dependent signal transduction pathways
    • Monteiro, H. P., and Stern, A. Redox modulation of tyrosine phosphorylation-dependent signal transduction pathways. Free Radic. Biol. Med., 21: 323-333, 1996.
    • (1996) Free Radic. Biol. Med. , vol.21 , pp. 323-333
    • Monteiro, H.P.1    Stern, A.2
  • 39
    • 0029984062 scopus 로고    scopus 로고
    • Antioxidants and redox regulation of gene transcription
    • Sen, C. K., and Packer, L. Antioxidants and redox regulation of gene transcription. FASEB J., 10: 709-720, 1996.
    • (1996) FASEB J. , vol.10 , pp. 709-720
    • Sen, C.K.1    Packer, L.2
  • 40
    • 0030597239 scopus 로고    scopus 로고
    • Three paths of stress relief
    • Canman, C. E., and Kastan, M. B. Three paths of stress relief. Nature (Lond.), 384: 213-214, 1996.
    • (1996) Nature (Lond.) , vol.384 , pp. 213-214
    • Canman, C.E.1    Kastan, M.B.2
  • 41
    • 0025321157 scopus 로고
    • Epidermal growth factor
    • Carpenter, G., and Cohen, S. Epidermal growth factor. J. Biol. Chem., 265: 7709-7712, 1990.
    • (1990) J. Biol. Chem. , vol.265 , pp. 7709-7712
    • Carpenter, G.1    Cohen, S.2
  • 42
    • 0029905354 scopus 로고    scopus 로고
    • Differential regulation of the MAP, SAP and RK/p38 kinases by Pyst1, a novel cytosolic dual-specificity phosphatase
    • Groom, L. A., Sneddon, A. A., Alessi, D. R., Dowd, S., and Keyse, S. M. Differential regulation of the MAP, SAP and RK/p38 kinases by Pyst1, a novel cytosolic dual-specificity phosphatase. EMBO J., 15: 3621-3632, 1996.
    • (1996) EMBO J. , vol.15 , pp. 3621-3632
    • Groom, L.A.1    Sneddon, A.A.2    Alessi, D.R.3    Dowd, S.4    Keyse, S.M.5
  • 44
    • 0030934694 scopus 로고    scopus 로고
    • Cloning of a novel mitogen-activated protein kinase kinase kinase, MEKK4, that selectively regulates the c-Jun amino terminal kinase pathway
    • Gerwins, P., Blank, J. L., and Johnson, G. L. Cloning of a novel mitogen-activated protein kinase kinase kinase, MEKK4, that selectively regulates the c-Jun amino terminal kinase pathway. J. Biol. Chem., 272: 8288-8295, 1997.
    • (1997) J. Biol. Chem. , vol.272 , pp. 8288-8295
    • Gerwins, P.1    Blank, J.L.2    Johnson, G.L.3
  • 45
    • 0032508714 scopus 로고    scopus 로고
    • A mammalian scaffold complex that selectively mediates MAP kinase activation
    • Washington DC
    • Whitmarsh, A. J., Cavanagh, J., Tournier, C., Yasuda, J., and Davis, R. J. A mammalian scaffold complex that selectively mediates MAP kinase activation. Science (Washington DC), 281: 1671-1674, 1998.
    • (1998) Science , vol.281 , pp. 1671-1674
    • Whitmarsh, A.J.1    Cavanagh, J.2    Tournier, C.3    Yasuda, J.4    Davis, R.J.5
  • 46
    • 0033548249 scopus 로고    scopus 로고
    • Different mitogen-activated protein kinase signaling pathways cooperate to regulate tumor necrosis factor a gene expression in T lymphocytes
    • Hoffmeyer, A., Grosse-Wilde, A., Flory, E., Neufeld, B., Kunz, M., Rapp, U. R., and Ludwig, S. Different mitogen-activated protein kinase signaling pathways cooperate to regulate tumor necrosis factor a gene expression in T lymphocytes. J. Biol. Chem., 274: 4319-4327, 1999.
    • (1999) J. Biol. Chem. , vol.274 , pp. 4319-4327
    • Hoffmeyer, A.1    Grosse-Wilde, A.2    Flory, E.3    Neufeld, B.4    Kunz, M.5    Rapp, U.R.6    Ludwig, S.7
  • 47
    • 0032958382 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase 7 (ERK7), a novel ERK with a C-terminal domain that regulates its activity, its cellular localization, and cell growth
    • Abe, M. K., Kuo, W-L., Hershenson, M. B., and Rosner, M. R. Extracellular signal-regulated kinase 7 (ERK7), a novel ERK with a C-terminal domain that regulates its activity, its cellular localization, and cell growth. Mol. Cell. Biol., 19: 1301-1312, 1999.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 1301-1312
    • Abe, M.K.1    Kuo, W.-L.2    Hershenson, M.B.3    Rosner, M.R.4
  • 48
    • 0024355092 scopus 로고
    • Autocrine interaction between TGFα and the EGF-receptor: Quantitative requirements for induction of the malignant phenotype
    • Di Marco, E., Pierce, J. H., Fleming, T. P., Kraus, M. H., Molloy, C. J., Aaronson, S. A., and Di Fiore, P. P. Autocrine interaction between TGFα and the EGF-receptor: quantitative requirements for induction of the malignant phenotype. Oncogene, 4: 831-838, 1989.
    • (1989) Oncogene , vol.4 , pp. 831-838
    • Di Marco, E.1    Pierce, J.H.2    Fleming, T.P.3    Kraus, M.H.4    Molloy, C.J.5    Aaronson, S.A.6    Di Fiore, P.P.7
  • 49
    • 0030946366 scopus 로고    scopus 로고
    • Hyperexpression of mitogen-activated protein kinase in human breast cancer
    • Sivaraman, V. S., Wang, H., Nuovo, G. J., and Malbon, C. C. Hyperexpression of mitogen-activated protein kinase in human breast cancer. J. Clin. Invest., 99: 1478-1483, 1997.
    • (1997) J. Clin. Invest. , vol.99 , pp. 1478-1483
    • Sivaraman, V.S.1    Wang, H.2    Nuovo, G.J.3    Malbon, C.C.4
  • 50
    • 0032553304 scopus 로고    scopus 로고
    • Convergence of progesterone and epidermal growth factor signaling in breast cancer. Potentiation of mitogen-activated protein kinase pathways
    • Lange, C. A., Richer, J. K., Shen, T., and Horwitz, K. B. Convergence of progesterone and epidermal growth factor signaling in breast cancer. Potentiation of mitogen-activated protein kinase pathways. J. Biol. Chem., 273: 31308-31316, 1998.
    • (1998) J. Biol. Chem. , vol.273 , pp. 31308-31316
    • Lange, C.A.1    Richer, J.K.2    Shen, T.3    Horwitz, K.B.4
  • 51
    • 0032530222 scopus 로고    scopus 로고
    • Elevated mitogen-activated protein kinase activity in estrogen-nonresponsive human breast cancer cells
    • Coutts, A. S., and Murphy, L. C. Elevated mitogen-activated protein kinase activity in estrogen-nonresponsive human breast cancer cells. Cancer Res., 58: 4071-4074, 1998.
    • (1998) Cancer Res. , vol.58 , pp. 4071-4074
    • Coutts, A.S.1    Murphy, L.C.2
  • 53
    • 0031921546 scopus 로고    scopus 로고
    • 1 arrest through an increase in Cip1/p21 concomitant with a decrease in kinase activity of CDKs and associated cyclins
    • 1 arrest through an increase in Cip1/p21 concomitant with a decrease in kinase activity of CDKs and associated cyclins. Clin. Cancer Res., 4: 1055-1064, 1998.
    • (1998) Clin. Cancer Res. , vol.4 , pp. 1055-1064
    • Zi, X.1    Feyes, D.K.2    Agarwal, R.3
  • 54
    • 0033600782 scopus 로고    scopus 로고
    • Modulation of mitogen-activated protein kinase activation and cell cycle regulators by the potent skin cancer preventive agent silymarin
    • Zi, X., and Agarwal, R. Modulation of mitogen-activated protein kinase activation and cell cycle regulators by the potent skin cancer preventive agent silymarin. Biochem. Biophys. Res. Commun., 263: 528-536, 1999.
    • (1999) Biochem. Biophys. Res. Commun. , vol.263 , pp. 528-536
    • Zi, X.1    Agarwal, R.2
  • 55
    • 0029043582 scopus 로고
    • How MAP kinases are regulated
    • Cobb, M. H., and Goldsmith, E. J. How MAP kinases are regulated. J. Biol. Chem., 270: 14843-14846, 1995.
    • (1995) J. Biol. Chem. , vol.270 , pp. 14843-14846
    • Cobb, M.H.1    Goldsmith, E.J.2
  • 56
    • 0029753773 scopus 로고    scopus 로고
    • The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and γ radiation. Duration of JNK activation may determine cell death and proliferation
    • Chen, Y. R., Wang, X., Templeton, D., Davis, R. J., and Tan, T. H. The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and γ radiation. Duration of JNK activation may determine cell death and proliferation. J. Biol. Chem., 277: 31929-31936, 1996.
    • (1996) J. Biol. Chem. , vol.277 , pp. 31929-31936
    • Chen, Y.R.1    Wang, X.2    Templeton, D.3    Davis, R.J.4    Tan, T.H.5
  • 57
    • 0029011218 scopus 로고
    • The MAPK signaling cascade
    • Seger, R., and Krebs, E. G. The MAPK signaling cascade. FASEB J., 9: 726-735, 1995.
    • (1995) FASEB J. , vol.9 , pp. 726-735
    • Seger, R.1    Krebs, E.G.2
  • 58
    • 0029973389 scopus 로고    scopus 로고
    • Cell-cycle control and its watchman
    • Jacks, T., and Weinberg, R. A. Cell-cycle control and its watchman. Nature (Lond.), 381: 643-644, 1996.
    • (1996) Nature (Lond.) , vol.381 , pp. 643-644
    • Jacks, T.1    Weinberg, R.A.2
  • 59
    • 0027938209 scopus 로고
    • Cyclins and cancer II: Cyclin D and CDK inhibitors come of age
    • Hunter, T., and Pines, J. Cyclins and cancer II: cyclin D and CDK inhibitors come of age. Cell, 79: 573-582, 1994.
    • (1994) Cell , vol.79 , pp. 573-582
    • Hunter, T.1    Pines, J.2
  • 60
    • 0028931265 scopus 로고
    • Principles of CDK regulation
    • Morgan, D. O. Principles of CDK regulation. Nature (Lond.), 374: 131-134, 1995.
    • (1995) Nature (Lond.) , vol.374 , pp. 131-134
    • Morgan, D.O.1
  • 61
    • 0030337951 scopus 로고    scopus 로고
    • Relevance of cyclin D1 and other molecular markers to cancer chemoprevention
    • Weinstein, I. B. Relevance of cyclin D1 and other molecular markers to cancer chemoprevention. J. Cell. Biochem., 25S: 23-28, 1996.
    • (1996) J. Cell. Biochem. , vol.25 S , pp. 23-28
    • Weinstein, I.B.1
  • 62
    • 0029119740 scopus 로고
    • Cell cycle control in mammalian cells: Role of cyclins, cyclin dependent kinases (CDKs), growth suppressor genes and cyclin-dependent kinase inhibitors (CDKIs)
    • Grana, X., and Reddy, P. Cell cycle control in mammalian cells: role of cyclins, cyclin dependent kinases (CDKs), growth suppressor genes and cyclin-dependent kinase inhibitors (CDKIs). Oncogene, 11: 211-219, 1995.
    • (1995) Oncogene , vol.11 , pp. 211-219
    • Grana, X.1    Reddy, P.2
  • 63
    • 0029664395 scopus 로고    scopus 로고
    • Regulation of p21WAF1/CIP1 expression through mitogen-activated protein kinase signaling pathway
    • Liu, Y., Martindale, J. L., Gorospe, M., and Holbrook, N. J. Regulation of p21WAF1/CIP1 expression through mitogen-activated protein kinase signaling pathway. Cancer Res., 56: 31-35, 1996.
    • (1996) Cancer Res. , vol.56 , pp. 31-35
    • Liu, Y.1    Martindale, J.L.2    Gorospe, M.3    Holbrook, N.J.4
  • 64
    • 0029925537 scopus 로고    scopus 로고
    • Up-regulation of cytokeratins 8 and 18 in human breast cancer T47D cells is retinoid-specific and retinoic acid receptor-dependent
    • Jing, Y., Zhang, J., Waxman, S., and Mira-y-Lopez, R. Up-regulation of cytokeratins 8 and 18 in human breast cancer T47D cells is retinoid-specific and retinoic acid receptor-dependent. Differentiation, 60: 109-117, 1996.
    • (1996) Differentiation , vol.60 , pp. 109-117
    • Jing, Y.1    Zhang, J.2    Waxman, S.3    Mira-y-Lopez, R.4
  • 65
    • 0030835893 scopus 로고    scopus 로고
    • Specific activation of a c-Jun NH2-terminul kinase isoform and induction of neunte outgrowth in PC-12 cells by staurosporine
    • Yao, R., Yoshihara, M., and Osada, H. Specific activation of a c-Jun NH2-terminul kinase isoform and induction of neunte outgrowth in PC-12 cells by staurosporine. J. Biol. Chem., 272; 18261-18266, 1997.
    • (1997) J. Biol. Chem. , vol.272 , pp. 18261-18266
    • Yao, R.1    Yoshihara, M.2    Osada, H.3
  • 66
    • 0032575591 scopus 로고    scopus 로고
    • Tumor necrosis factor signaling to stress-activated protein kinases (SAPK)/Jun HH2-terminal kinase (JNK) and p38
    • Yuasa, T., Ohno, S., Kehrl, J. H., and Kyriakis, J. M. Tumor necrosis factor signaling to stress-activated protein kinases (SAPK)/Jun HH2-terminal kinase (JNK) and p38. J. Biol. Chem., 273: 22681-22692, 1998.
    • (1998) J. Biol. Chem. , vol.273 , pp. 22681-22692
    • Yuasa, T.1    Ohno, S.2    Kehrl, J.H.3    Kyriakis, J.M.4
  • 67
    • 0033613857 scopus 로고    scopus 로고
    • Identification of an extracellular signal-regulated kinase (ERK) docking site in ribosomal S6 kinase, a sequence critical for activation by ERK in vivo
    • Smith, J. A., Poteet-Smith, C. E., Malarkey, K., and Sturgill, T. W. Identification of an extracellular signal-regulated kinase (ERK) docking site in ribosomal S6 kinase, a sequence critical for activation by ERK in vivo. J. Biol. Chem., 274: 2893-2898, 1999.
    • (1999) J. Biol. Chem. , vol.274 , pp. 2893-2898
    • Smith, J.A.1    Poteet-Smith, C.E.2    Malarkey, K.3    Sturgill, T.W.4
  • 68
    • 0031034574 scopus 로고    scopus 로고
    • Antiapoptotic signalling by insulin-like growth factor-1 receptor, phosphatidylinositol 3-kinase, and Akt
    • Kulik, G., Klippel, A., and Weber, M. J. Antiapoptotic signalling by insulin-like growth factor-1 receptor, phosphatidylinositol 3-kinase, and Akt. Mol. Cell. Biol., 17: 1595-1606, 1997.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 1595-1606
    • Kulik, G.1    Klippel, A.2    Weber, M.J.3
  • 69
    • 0030575526 scopus 로고    scopus 로고
    • Why are there so many CDK inhibitors
    • Xiaong, Y. Why are there so many CDK inhibitors. Biochim. Biophys. Acta, 1288: 1-5, 1996.
    • (1996) Biochim. Biophys. Acta , vol.1288 , pp. 1-5
    • Xiaong, Y.1
  • 70
    • 0029034451 scopus 로고
    • MyoD-induced expression of p21 inhibits cyclin-dependent kinase activity upon myocyte terminal differentiation
    • Guo, K., Wang, J., Andres, V., Smith, R. C., and Walsh, K. MyoD-induced expression of p21 inhibits cyclin-dependent kinase activity upon myocyte terminal differentiation. Mol. Cell. Biol., 15: 3823-3829, 1995.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 3823-3829
    • Guo, K.1    Wang, J.2    Andres, V.3    Smith, R.C.4    Walsh, K.5
  • 71
    • 0029020945 scopus 로고
    • Involvement of the cell-cycle inhibitor Cip1/WAF1 and the E1A-associated p300 protein in terminal differentiation
    • Missero, C., Calautti, E., Eckner, R., Chin, J., Tsai, L. H., Livingston, D. M., and Dotto G. P. Involvement of the cell-cycle inhibitor Cip1/WAF1 and the E1A-associated p300 protein in terminal differentiation. Proc. Natl. Acad. Sci. USA, 92: 5451-5455, 1995.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 5451-5455
    • Missero, C.1    Calautti, E.2    Eckner, R.3    Chin, J.4    Tsai, L.H.5    Livingston, D.M.6    Dotto, G.P.7
  • 72
    • 0029031949 scopus 로고
    • The melanoma differentiation-associated gene mda-6, which encodes the cyclin-dependent kinase inhibitor p21, is differentially expressed during growth, differentiation and progression in human melanoma cells
    • Jiang, H., Lin, J., Su, Z., Herlyn, M., Kerbel, R. S., Weissman, B. E., Welch, D. R., and Fisher, P. B. The melanoma differentiation-associated gene mda-6, which encodes the cyclin-dependent kinase inhibitor p21, is differentially expressed during growth, differentiation and progression in human melanoma cells. Oncogene, 10: 1855-1864, 1995.
    • (1995) Oncogene , vol.10 , pp. 1855-1864
    • Jiang, H.1    Lin, J.2    Su, Z.3    Herlyn, M.4    Kerbel, R.S.5    Weissman, B.E.6    Welch, D.R.7    Fisher, P.B.8
  • 73
    • 0029670477 scopus 로고    scopus 로고
    • Kip1 accumulation during the cell cycle
    • Washington DC
    • Kip1 accumulation during the cell cycle. Science (Washington DC), 271: 1861-1864, 1996.
    • (1996) Science , vol.271 , pp. 1861-1864
    • Hengst, L.1    Reed, S.I.2
  • 74
    • 0033178914 scopus 로고    scopus 로고
    • Acquisition of neuroendocrine characteristics by prostate tumor cells is reversible: Implications for prostate cancer progression
    • Cox, M. E., Deeble, P. D., Lakhani, S., and Parsons, S. J. Acquisition of neuroendocrine characteristics by prostate tumor cells is reversible: implications for prostate cancer progression. Cancer Res., 59: 3821-3830, 1999.
    • (1999) Cancer Res. , vol.59 , pp. 3821-3830
    • Cox, M.E.1    Deeble, P.D.2    Lakhani, S.3    Parsons, S.J.4


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