Inhibition of TPA-induced tumor promotion in CD-1 mouse epidermis by a polyphenolic fraction from grape seeds

Cancer Letters

Volumn 135, Issue 2, 1999, Pages 151-157

  Bomser, J A ^a   Singletary, K W ^a   Wallig, M A ^a   Smith, M A L ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

Grape seed; Polyphenolic; Proanthocyanidin; Skin tumor

Indexed keywords

BIOCHEMICAL MARKER; DIMETHYLBENZ[A]ANTHRACENE; MYELOPEROXIDASE; ORNITHINE DECARBOXYLASE; PHORBOL 13 ACETATE 12 MYRISTATE; PLANT EXTRACT; POLYPHENOL; TRACONOL; UNCLASSIFIED DRUG;

ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; ENZYME ACTIVITY; EPIDERMIS; FEMALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SKIN TUMOR; TOPICAL DRUG ADMINISTRATION; TUMOR PROMOTION;

9,10-DIMETHYL-1,2-BENZANTHRACENE; ANIMALS; ANTHOCYANINS; CARCINOGENS; DRUG SCREENING ASSAYS, ANTITUMOR; EFLORNITHINE; ENZYME INHIBITORS; FEMALE; FLAVONOIDS; MICE; NEOPLASMS, EXPERIMENTAL; ORNITHINE DECARBOXYLASE; PEROXIDASE; PHENOLS; POLYMERS; PROANTHOCYANIDINS; ROSALES; SEEDS; SKIN NEOPLASMS; TETRADECANOYLPHORBOL ACETATE;

EID: 0032991077     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(98)00289-4     Document Type: Article

References (23)

1. Block G., Patterson B., Subar A. Fruit, vegetables and cancer prevention: a review of the epidemiological evidence. Nutr. Cancer. 17:1992;1-29.
2. Wattenberg L.W. Inhibition of tumorigenesis in animals. Stewart B.W., McGregor D., Kleihues P. Principles of Chemoprevention. 1996;151 International Agency for Research on Cancer, Lyon.
3. Stoner G.D., Mukhtar H. Polyphenols as cancer chemopreventive agents. J. Cell. Biochem. 22:1995;169-180.
4. Escribano-Bailon M.T., Gutierrez-Fernandez Y., Rivas-Gonzalo J.C., Santos-Buelga C. Characterization of procyanidins of Vitis vinifera variety Tinta del Pais grape seeds. J. Agric. Food Chem. 40:1992;1794-1799.
5. Mukhtar H., Katiyar S.K., Agarwal R. Green tea and skin-anticarcinogenic effects. J. Invest Dermatol. 102:1994;3-7.
6. Castonguay A., Gali H.U., Perchellet E.M., Gao X.M., Boukharta M., Jalbert G., Okuda T., Yoshida T., Hatano T., Perchellet J.-P. Antitumorigenic and antipromoting activities of ellagic acid, ellagitannins and oligomeric anthocyanin and procyanidin. Int. J. Oncol. 10:1997;367-373.
7. Fuleki T., Ricardo da Silva J.M. J. Agric. Food Chem. 45:1997;1156-1160.
8. Gendimenico G.J., Capetola R.J., Rosenthale M.E., McGuire J.L., Mezick J.A. Retinoid modulation of phorbol ester effects in skin. Methods Enzymol. 190:1990;346-352.
9. Wei H., Frenkel K. Suppression of tumor promoter-induced oxidative events and DNA damage in vivo by sarcophytol A: a possible mechanism of anti-promotion. Cancer Res. 52:1992;2298-2303.
10. Gao X.M., Perchellet E.M., Gali H.U., Rodriquez L., Hemingway R.W., Perchellet J.P. Int. J. Oncol. 5:1994;285-292.
11. Katiyar S.K., Agarwal R., Wood G.S., Mukhtar H. Inhibition of 12-O-tetradecanoylphorbol-13-acetate-caused tumor promotion in 7,12-dimethylbenz{a}anthracene-initiated SENCAR mouse skin by a polyphenolic fraction isolated from green tea. Cancer Res. 52:1992;6890-6897.
12. Clifford A.J., Ebeler S.E., Ebeler J.D., Bills N.D., Hinrichs S.H., Teisseder P.-L., Waterhouse A.L. Delayed tumor onset in transgenic mice fed an amino acid-based diet supplemented with red wine solids. Am. J. Clin. Nutr. 64:1996;748-756.
13. Auvinen M. Cell transformation, invasion, and angiogenesis: a regulatory role for ornithine decarboxylase and polyamines? J. Natl. Cancer Inst. 89:1997;533-537.
14. O'Brien T.G., Megosh L.C., Gilliard G., Soler A.P. Ornithine decarboxylase overexpression is a sufficient condition for tumor promotion in mouse skin. Cancer Res. 57:1997;2630-2637.
15. Kubota S., Kiyosawa H., Nomura Y., Yamada T., Seyama Y. Ornithine decarboxylase overexpression in mouse 10T1/2 fibroblasts: cellular transformation and invasion. J. Natl. Cancer Inst. 89:1997;567-571.
16. Agarwal R., Katiyar S.K., Zaidi S., Mukhtar H. Inhibition of skin tumor promoter-caused induction of epidermal ornithine decarboxylase in SENCAR mice by polyphenolic fraction isolated from green tea and its individual epicatechin derivatives. Cancer Res. 52:1992;3582-3588.
17. Gali H.U., Perchellet E.M., Gao X.M., Karchesy J.J., Perchellet J.P. Comparison of the inhibitory effects of monomeric, dimeric and trimeric procyanidins on the biochemical markers of skin tumor promotion in mouse epidermis in vivo. Planta Medica. 60:1994;235-239.
18. Pegg A.E., Shantz L.M., Coleman C.S. Ornithine decarboxylase as a target for chemoprevention. J. Cell. Biochem. 22:1995;132-138.
19. Weitzman S.A., Gordon L.I. Inflammation and cancer: role of phagocyte-generated oxidants in carcinogenesis. Blood. 76:1990;655-663.
20. Bagchi D., Garg A., Krohn R.L., Bagchi M., Tran M.X., Stohs S.J. Oxygen free radical scavenging abilities of vitamin C and E, and a grape seed proanthocyanidin extract in vitro. Res. Commun. Mol. Pathol. Pharm. 95:1997;179-188.
21. Tebib K., Rouanet J.M., Besancon P. Antioxidant effects of dietary polymeric grape seed tannins in tissues of rats fed a high cholesterol-vitamin E-deficient diet. Food Chem. 59:1997;135-141.
22. Prieur C., Rigaud J., Cheynier V., Moutounet M. Oligomeric and polymeric procyanidins from grape seeds. Phytochemistry. 36:1994;781-784.
23. Fuleki T., Ricardo da Silva J.M. J. Agric. Food Chem. 45:1997;1156-1160.