메뉴 건너뛰기




Volumn 20, Issue 2, 2000, Pages 103-120

Tolerance and immunity in the intestinal immune system

Author keywords

Mucosal adjuvants; Oral tolerance; Regulatory T cells; T cell anergy

Indexed keywords

ADOPTIVE TRANSFER; ANTIGEN PRESENTATION; ANTIGEN SPECIFICITY; CLONAL ANERGY; HUMAN; IMMUNOLOGICAL TOLERANCE; IMMUNOSTIMULATION; INTESTINE LYMPHATIC TISSUE; MUCOSAL IMMUNITY; NONHUMAN; PRIORITY JOURNAL; REVIEW; T LYMPHOCYTE ACTIVATION;

EID: 0033932344     PISSN: 10408401     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (64)

References (89)
  • 1
    • 0027422089 scopus 로고
    • Chronic intestinal inflammation: An unexpected outcome in cytokine or T-cell receptor mutant mice
    • Strober, W. and Ehrhardt, R. O., Chronic intestinal inflammation: an unexpected outcome in cytokine or T-cell receptor mutant mice, Cell, 75, 203-205, 1993.
    • (1993) Cell , vol.75 , pp. 203-205
    • Strober, W.1    Ehrhardt, R.O.2
  • 2
    • 0000253355 scopus 로고
    • Suppression of type II collagen-induced arthritis by intragastric administration of soluble type II collagen
    • Nagler-Anderson, C., Bober, L. A., Robinson, M. E., Siskind, G. W., and Thorbecke, G. J., Suppression of type II collagen-induced arthritis by intragastric administration of soluble type II collagen, Proc. Natl. Acad. Sci. U.S.A., 83, 7443-7446, 1986.
    • (1986) Proc. Natl. Acad. Sci. U.S.A. , vol.83 , pp. 7443-7446
    • Nagler-Anderson, C.1    Bober, L.A.2    Robinson, M.E.3    Siskind, G.W.4    Thorbecke, G.J.5
  • 3
    • 0022615333 scopus 로고
    • Gastric administration of type II collagen delays the onset and severity of collagen-induced arthritis in rats
    • Thompson, H. S. G. and Staines, N. A., Gastric administration of type II collagen delays the onset and severity of collagen-induced arthritis in rats, Clin. Exp. Immunol., 64, 581-586, 1986.
    • (1986) Clin. Exp. Immunol. , vol.64 , pp. 581-586
    • Thompson, H.S.G.1    Staines, N.A.2
  • 5
    • 0030847054 scopus 로고    scopus 로고
    • Oral tolerance: Immune mechanisms and treatment of autoimmune diseases
    • Weiner, H. L., Oral tolerance: immune mechanisms and treatment of autoimmune diseases, Immunol. Today, 19, 335-339, 1997.
    • (1997) Immunol. Today , vol.19 , pp. 335-339
    • Weiner, H.L.1
  • 6
    • 0032707194 scopus 로고    scopus 로고
    • Basic mechanisms and clinical implications of oral tolerance
    • Mowat, A. M., Basic mechanisms and clinical implications of oral tolerance, Curr. Opinion in Gastro, 15, 546-556, 1999.
    • (1999) Curr. Opinion in Gastro , vol.15 , pp. 546-556
    • Mowat, A.M.1
  • 7
    • 0000689557 scopus 로고    scopus 로고
    • Oral tolerance. Physiological basis and clinical applications
    • Ogra, P. L., Mestecky, J., Lamm, M. E., Strober, W., Bienenstock, J., and McGhee, J., Eds., Academic Press, San Diego, CA
    • Mowat, A. M. and Weiner, H. L., Oral tolerance. Physiological basis and clinical applications, in Mucosal Immunology, Ogra, P. L., Mestecky, J., Lamm, M. E., Strober, W., Bienenstock, J., and McGhee, J., Eds., Academic Press, San Diego, CA, 1999, 587-618.
    • (1999) Mucosal Immunology , pp. 587-618
    • Mowat, A.M.1    Weiner, H.L.2
  • 8
    • 0029031681 scopus 로고
    • Peripheral deletion of antigen-reactive T cells in oral tolerance
    • Chen, Y., Inobe, J., Marks, R., Gonnella, P., Kuchroo, V. J., and Weiner, H. L., Peripheral deletion of antigen-reactive T cells in oral tolerance, Nature, 376, 177-180, 1994.
    • (1994) Nature , vol.376 , pp. 177-180
    • Chen, Y.1    Inobe, J.2    Marks, R.3    Gonnella, P.4    Kuchroo, V.J.5    Weiner, H.L.6
  • 9
    • 0030587132 scopus 로고    scopus 로고
    • High dose oral tolerance in ovalbumin TCR-transgenic mice. Systemic neutralization of IL-12 augments TGF-β secretion and T-cell apoptosis
    • Marth, T., Strober, W., and Kelsall, B. L., High dose oral tolerance in ovalbumin TCR-transgenic mice. Systemic neutralization of IL-12 augments TGF-β secretion and T-cell apoptosis, J. Immunol., 157, 2348-2357, 1996.
    • (1996) J. Immunol. , vol.157 , pp. 2348-2357
    • Marth, T.1    Strober, W.2    Kelsall, B.L.3
  • 10
    • 0030938148 scopus 로고    scopus 로고
    • Regulation of transforming growth factor β by interleukin-12
    • Marth, T., Strober,W., Seder, R. A., and Kelsall, B. L., Regulation of transforming growth factor β by interleukin-12, Eur. J. Immunol., 27, 1213-1217, 1997.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 1213-1217
    • Marth, T.1    Seder, R.A.2    Kelsall, B.L.3
  • 11
    • 0031758888 scopus 로고    scopus 로고
    • Mucosal immunity in relation to the development of oral tolerance/sensitization
    • Holt, P. G., Mucosal immunity in relation to the development of oral tolerance/sensitization, Allergy, 53, 16-19, 1998.
    • (1998) Allergy , vol.53 , pp. 16-19
    • Holt, P.G.1
  • 12
    • 0032524991 scopus 로고    scopus 로고
    • Transplacental priming of the human immune system to environmental allergens: Universal skewing of initial T-cell responses toward the Th2 cytokine profile
    • Prescott, S. L., Macaubus, C., Holt, B. J., Smallacombe, T. B., Loh, R., Sly, P, D., and Holt P. G., Transplacental priming of the human immune system to environmental allergens: universal skewing of initial T-cell responses toward the Th2 cytokine profile, J. Immunol., 160, 4730-4737, 1998.
    • (1998) J. Immunol. , vol.160 , pp. 4730-4737
    • Prescott, S.L.1    Macaubus, C.2    Holt, B.J.3    Smallacombe, T.B.4    Loh, R.5    Sly, P.D.6    Holt, P.G.7
  • 13
    • 0033573788 scopus 로고    scopus 로고
    • Development of allergen-specific T-cell memory in atopic and normal children
    • Prescott, S. L., Macaubus, C., Smallacombe, T., Holt, B. J., Sly, P. D., and Holt, P. G., Development of allergen-specific T-cell memory in atopic and normal children, Lancet, 353, 196-200, 1999.
    • (1999) Lancet , vol.353 , pp. 196-200
    • Prescott, S.L.1    Macaubus, C.2    Smallacombe, T.3    Holt, B.J.4    Sly, P.D.5    Holt, P.G.6
  • 14
    • 0030002891 scopus 로고    scopus 로고
    • Primary allergic sensitization to environmental antigens: Perinatal T-cell priming as a determinant of response phenotype in adulthood
    • Holt, P. G., Primary allergic sensitization to environmental antigens: perinatal T-cell priming as a determinant of response phenotype in adulthood, J. Exp. Med., 183, 1297-1301, 1996.
    • (1996) J. Exp. Med. , vol.183 , pp. 1297-1301
    • Holt, P.G.1
  • 15
    • 0031571230 scopus 로고    scopus 로고
    • The requirement of intestinal bacterial flora for the development of an ige production system fully susceptible to oral tolerance induction
    • Sudo, N., Sawamura, S.-A., Tanaka, K., Aiba, Y., Kubo, C., and Koga, Y., The requirement of intestinal bacterial flora for the development of an IgE production system fully susceptible to oral tolerance induction, J. Immunol., 159, 1739-1745, 1997.
    • (1997) J. Immunol. , vol.159 , pp. 1739-1745
    • Sudo, N.1    Sawamura, S.-A.2    Tanaka, K.3    Aiba, Y.4    Kubo, C.5    Koga, Y.6
  • 16
    • 0030820364 scopus 로고    scopus 로고
    • Interferon-γ receptor deficient mice exhibit impaired gut mucosal immune responses but intact oral tolerance
    • Kjerrulf, M., Grdic, D., Ekman, L., Schon, K., Vajdy, M., and Lycke, N. Y., Interferon-γ receptor deficient mice exhibit impaired gut mucosal immune responses but intact oral tolerance, Immunology, 92, 60-68, 1997.
    • (1997) Immunology , vol.92 , pp. 60-68
    • Kjerrulf, M.1    Grdic, D.2    Ekman, L.3    Schon, K.4    Vajdy, M.5    Lycke, N.Y.6
  • 18
    • 0344690179 scopus 로고    scopus 로고
    • Orally induced peripheral nonresponsiveness is maintained in the absence of functional Th1 or Th2 cells
    • Shi, H. N., Grusby, M. J., and Nagler-Anderson, C., Orally induced peripheral nonresponsiveness is maintained in the absence of functional Th1 or Th2 cells, J. Immunol., 162, 5143-5148, 1999.
    • (1999) J. Immunol. , vol.162 , pp. 5143-5148
    • Shi, H.N.1    Grusby, M.J.2    Nagler-Anderson, C.3
  • 19
    • 0032737340 scopus 로고    scopus 로고
    • Normal induction of oral tolerance in the absence of a functional IL-12-dependent IFN-γ signaling pathway
    • Mowat, A. M., Steel, M., Leishman, A. J., and Garside, P., Normal induction of oral tolerance in the absence of a functional IL-12-dependent IFN-γ signaling pathway, J. Immunol., 163, 4728-4736, 1999.
    • (1999) J. Immunol. , vol.163 , pp. 4728-4736
    • Mowat, A.M.1    Steel, M.2    Leishman, A.J.3    Garside, P.4
  • 22
    • 0032473406 scopus 로고    scopus 로고
    • Monocyte chemotactic protein 1 regulates oral tolerance induction by inhibition of T helper cell 1-related cytokines
    • Karpus, W. J., Kennedy, K. J, Kunkel, S. L., and Lukacs, N. W., Monocyte chemotactic protein 1 regulates oral tolerance induction by inhibition of T helper cell 1-related cytokines, J. Exp. Med., 187, 733-741, 1998.
    • (1998) J. Exp. Med. , vol.187 , pp. 733-741
    • Karpus, W.J.1    Kennedy, K.J.2    Kunkel, S.L.3    Lukacs, N.W.4
  • 23
    • 0026042008 scopus 로고
    • Oral tolerance in experimental autoimmune encephalomyelitis. III. Evidence for clonal anergy
    • Whitacre, C. C., Gienapp, I. E., Orosz, C. G., and Bitar, D. M., Oral tolerance in experimental autoimmune encephalomyelitis. III. Evidence for clonal anergy, J. Immunol., 147, 2155-2162, 1991.
    • (1991) J. Immunol. , vol.147 , pp. 2155-2162
    • Whitacre, C.C.1    Gienapp, I.E.2    Orosz, C.G.3    Bitar, D.M.4
  • 24
    • 0028040873 scopus 로고
    • In vivo tolerization of Th1 lymphocytes following a single feeding with ovalbumin: Anergy in the absence of suppression
    • Melamed, D. and Friedman, A., In vivo tolerization of Th1 lymphocytes following a single feeding with ovalbumin: anergy in the absence of suppression, Eur. J. Immunol, 24, 1974-1979, 1994.
    • (1994) Eur. J. Immunol , vol.24 , pp. 1974-1979
    • Melamed, D.1    Friedman, A.2
  • 25
    • 0028358048 scopus 로고
    • Induction of anergy or active suppression following oral tolerance is determined by antigen dosage
    • Friedman, A. and Weiner, H. L., Induction of anergy or active suppression following oral tolerance is determined by antigen dosage, Proc. Natl. Acad. Sci. U.S.A., 91, 6688-6692, 1994.
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 6688-6692
    • Friedman, A.1    Weiner, H.L.2
  • 26
    • 0030586668 scopus 로고    scopus 로고
    • Direct measurement of anergy of antigen-specific T cells following oral tolerance induction
    • Van Houten, N. and Blake, S. F., Direct measurement of anergy of antigen-specific T cells following oral tolerance induction, J. Immunol., 157, 1336-1341, 1996.
    • (1996) J. Immunol. , vol.157 , pp. 1336-1341
    • Van Houten, N.1    Blake, S.F.2
  • 27
    • 0032100767 scopus 로고    scopus 로고
    • The induction of rapid T-cell activation and tolerance by systemic presentation of an orally administered antigen
    • Gutgemann, I., Fahrer, A. M., Altman, J. D., Davis, M. M., and Chien, Y.-H., The induction of rapid T-cell activation and tolerance by systemic presentation of an orally administered antigen, Immunity, 8, 667-673, 1998.
    • (1998) Immunity , vol.8 , pp. 667-673
    • Gutgemann, I.1    Fahrer, A.M.2    Altman, J.D.3    Davis, M.M.4    Chien, Y.-H.5
  • 28
    • 0033563273 scopus 로고    scopus 로고
    • Antigen-specific T-cell activation and proliferation during oral tolerance induction
    • Sun, J., Dirden-Kramer, B., Ito, K., Ernst, P. B., and Van Houten, N., Antigen-specific T-cell activation and proliferation during oral tolerance induction, J. Immunol., 162, 5868-5875, 1999.
    • (1999) J. Immunol. , vol.162 , pp. 5868-5875
    • Sun, J.1    Dirden-Kramer, B.2    Ito, K.3    Ernst, P.B.4    Van Houten, N.5
  • 29
    • 0032789856 scopus 로고    scopus 로고
    • Visualizing the T-cell response elicited by oral administration of soluble protein antigen
    • Williamson, E., O'Malley, J. M., and Viney, J. L., Visualizing the T-cell response elicited by oral administration of soluble protein antigen, Immunology, 97, 565-572, 1999.
    • (1999) Immunology , vol.97 , pp. 565-572
    • Williamson, E.1    O'Malley, J.M.2    Viney, J.L.3
  • 32
    • 0029057590 scopus 로고
    • + T cells anergized by high dose feeding establish oral tolerance to antibody responses when transferred in SCID and nude mice
    • + T cells anergized by high dose feeding establish oral tolerance to antibody responses when transferred in SCID and nude mice, J. Immunol., 154, 6238-6245, 1995.
    • (1995) J. Immunol. , vol.154 , pp. 6238-6245
    • Hirahara, K.1    Hisatsune, T.2    Nishijima, K.-I.3    Kato, H.4    Shiho, O.5    Kaminogawa, S.6
  • 35
    • 0018730879 scopus 로고
    • Inhibition of specific immune responses by feeding protein antigens. IV. Evidence for tolerance and specific active suppression of cell-mediated immune responses to ovalbumin
    • Miller, S. D. and Hanson, D. G., Inhibition of specific immune responses by feeding protein antigens. IV. Evidence for tolerance and specific active suppression of cell-mediated immune responses to ovalbumin, J. Immunol., 123, 2344-2350, 1979.
    • (1979) J. Immunol. , vol.123 , pp. 2344-2350
    • Miller, S.D.1    Hanson, D.G.2
  • 37
    • 0030060229 scopus 로고    scopus 로고
    • + suppressor T cells
    • + suppressor T cells, J. Immunol., 156, 916-921, 1996.
    • (1996) J. Immunol. , vol.156 , pp. 916-921
    • Ke, Y.1    Kapp, J.A.2
  • 39
    • 0027521572 scopus 로고
    • Interleukin-10 deficient mice develop chronic enterocolitis
    • Kuhn, R., Lohler, J., Rennick, D., Rajewsky, K., and Muller, W., Interleukin-10 deficient mice develop chronic enterocolitis, Cell, 75, 263-274, 1993.
    • (1993) Cell , vol.75 , pp. 263-274
    • Kuhn, R.1    Lohler, J.2    Rennick, D.3    Rajewsky, K.4    Muller, W.5
  • 40
    • 0032425062 scopus 로고    scopus 로고
    • Helicobacter hepaticus triggers colitis in specific pathogen free interleukin-10 (IL-10) deficient mice through an IL-12 and gamma interferon dependent mechanism
    • Kullberg, M. C., Ward, J. M., Gorelick, P. L., Caspar, P., Hieny, S., Cheever, A., Jankovic, D., and Sher, A., Helicobacter hepaticus triggers colitis in specific pathogen free interleukin-10 (IL-10) deficient mice through an IL-12 and gamma interferon dependent mechanism, Infect. Immunity, 66, 5157-5166, 1998.
    • (1998) Infect. Immunity , vol.66 , pp. 5157-5166
    • Kullberg, M.C.1    Ward, J.M.2    Gorelick, P.L.3    Caspar, P.4    Hieny, S.5    Cheever, A.6    Jankovic, D.7    Sher, A.8
  • 41
    • 0032780043 scopus 로고    scopus 로고
    • Cyclooxygenase-2-dependent arachidonic acid metabolites are essential modulators of the intestinal immune response to dietary antigen
    • Newberry, R. D., Stenson, W. F., and Lorenz, R. G., Cyclooxygenase-2-dependent arachidonic acid metabolites are essential modulators of the intestinal immune response to dietary antigen, Nat. Med., 5, 900-906, 1999.
    • (1999) Nat. Med. , vol.5 , pp. 900-906
    • Newberry, R.D.1    Stenson, W.F.2    Lorenz, R.G.3
  • 42
    • 0030589298 scopus 로고    scopus 로고
    • Memory T-cell development in the absence of specific antigen priming
    • Lee, W. T., Cole-Calkins, J., and Street, N. E., Memory T-cell development in the absence of specific antigen priming, J. Immunol., 157, 5300-5307, 1996.
    • (1996) J. Immunol. , vol.157 , pp. 5300-5307
    • Lee, W.T.1    Cole-Calkins, J.2    Street, N.E.3
  • 43
    • 0030963432 scopus 로고    scopus 로고
    • Functional differentiation of T cells in the intestine of T-cell receptor transgenic mice
    • Hurst, S. D., Sitterding, S. M., Ji, S., and Barrett, T. A., Functional differentiation of T cells in the intestine of T-cell receptor transgenic mice, Proc. Natl. Acad. Sci. U.S.A., 94, 3920-3924, 1997.
    • (1997) Proc. Natl. Acad. Sci. U.S.A. , vol.94 , pp. 3920-3924
    • Hurst, S.D.1    Sitterding, S.M.2    Ji, S.3    Barrett, T.A.4
  • 45
    • 0030966217 scopus 로고    scopus 로고
    • Induction of peripheral T-cell tolerance in vivo requires CTLA-4 engagement
    • Perez, V. L., van Parijs, L., Biuckians, A., Zheng, X. X., Strom, T. B., and Abbas, A. K., Induction of peripheral T-cell tolerance in vivo requires CTLA-4 engagement, Immunity, 6, 411-417, 1997.
    • (1997) Immunity , vol.6 , pp. 411-417
    • Perez, V.L.1    Van Parijs, L.2    Biuckians, A.3    Zheng, X.X.4    Strom, T.B.5    Abbas, A.K.6
  • 46
    • 0032522488 scopus 로고    scopus 로고
    • CTLA-4 regulates tolerance induction and T-cell differentiation in vivo
    • Walunas, T. L. and Bluestone, J. A., CTLA-4 regulates tolerance induction and T-cell differentiation in vivo, J. Immunol., 160, 3855-3860, 1998.
    • (1998) J. Immunol. , vol.160 , pp. 3855-3860
    • Walunas, T.L.1    Bluestone, J.A.2
  • 48
    • 0033557712 scopus 로고    scopus 로고
    • Mucosally induced systemic T-cell unresponsiveness to ovalbumin requires CD40 ligand-CD40 interactions
    • Kweon, M.-N., Fujihashi, K., Wakatsuki, Y., Koga, T., Yamamoto, M., McGhee, J. R., and Kiyono, H., Mucosally induced systemic T-cell unresponsiveness to ovalbumin requires CD40 ligand-CD40 interactions, J. Immunol., 162, 1904-1909, 1999.
    • (1999) J. Immunol. , vol.162 , pp. 1904-1909
    • Kweon, M.-N.1    Fujihashi, K.2    Wakatsuki, Y.3    Koga, T.4    Yamamoto, M.5    McGhee, J.R.6    Kiyono, H.7
  • 50
    • 0032528838 scopus 로고    scopus 로고
    • Highly polarized HLA class II antigen processing and presentation by human intestinal epithelial cells
    • Hershberg, R. M., Cho, D. H., Youakim, A., Bradley, M. B., Lee, J. S., Framson, P. E., and Nepom, G. T., Highly polarized HLA Class II antigen processing and presentation by human intestinal epithelial cells, J. Clin. Invest., 102, 792-803, 1998.
    • (1998) J. Clin. Invest. , vol.102 , pp. 792-803
    • Hershberg, R.M.1    Cho, D.H.2    Youakim, A.3    Bradley, M.B.4    Lee, J.S.5    Framson, P.E.6    Nepom, G.T.7
  • 51
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • Banchereau, J. and Steinman, R. M., Dendritic cells and the control of immunity, Nature, 392, 245-252, 1998.
    • (1998) Nature , vol.392 , pp. 245-252
    • Banchereau, J.1    Steinman, R.M.2
  • 52
    • 0028032963 scopus 로고
    • The tissue distribution of the B7-2 costimulator in mice: Abundant expression on dendritic cells in situ and during maturation in vitro
    • Inaba, K., Witmer-Pack, M., Inaba, M., Hathcock, K. S., Sakuta, H., Azuma, M., Yagita, H., Okumura, K., Linsley, P. S., and Ikehara, S., The tissue distribution of the B7-2 costimulator in mice: abundant expression on dendritic cells in situ and during maturation in vitro, J. Exp. Med., 180, 1849-1860, 1994.
    • (1994) J. Exp. Med. , vol.180 , pp. 1849-1860
    • Inaba, K.1    Witmer-Pack, M.2    Inaba, M.3    Hathcock, K.S.4    Sakuta, H.5    Azuma, M.6    Yagita, H.7    Okumura, K.8    Linsley, P.S.9    Ikehara, S.10
  • 53
    • 0030067796 scopus 로고    scopus 로고
    • Distinct populations of dendritic cells are present in the subepithelial dome and T-cell regions of the murine Peyer's patch
    • Kelsall, B. L. and Strober, W., Distinct populations of dendritic cells are present in the subepithelial dome and T-cell regions of the murine Peyer's patch, J. Exp. Med., 183, 237-247, 1996.
    • (1996) J. Exp. Med. , vol.183 , pp. 237-247
    • Kelsall, B.L.1    Strober, W.2
  • 56
    • 0033074360 scopus 로고    scopus 로고
    • + dendritic cells generate an immune response after subcutaneous injection without homing to the draining lymph node
    • + dendritic cells generate an immune response after subcutaneous injection without homing to the draining lymph node, J. Exp. Med., 189, 593-598, 1999.
    • (1999) J. Exp. Med. , vol.189 , pp. 593-598
    • Smith, A.L.1    Fazekas De St Groth, B.2
  • 57
    • 0032189552 scopus 로고    scopus 로고
    • The evolution of self-tolerance: A new cell arises to meet the challenge of self-reactivity
    • Fazekas de St. Groth, B., The evolution of self-tolerance: a new cell arises to meet the challenge of self-reactivity, Immunol. Today, 19, 448-454, 1998.
    • (1998) Immunol. Today , vol.19 , pp. 448-454
    • Fazekas De St Groth, B.1
  • 58
    • 0031179646 scopus 로고    scopus 로고
    • IL-12 deficient dendritic cells, generated in the presence of prostaglandin E2, promote type 2 cytokine production in maturing human naive T helper cells
    • Kalinski, P., Hilkens, C. M., Snijders, A., Snijdewint, F. G., and Kapsenberg, M. L., IL-12 deficient dendritic cells, generated in the presence of prostaglandin E2, promote type 2 cytokine production in maturing human naive T helper cells, J. Immunol., 159, 28-35, 1997.
    • (1997) J. Immunol. , vol.159 , pp. 28-35
    • Kalinski, P.1    Hilkens, C.M.2    Snijders, A.3    Snijdewint, F.G.4    Kapsenberg, M.L.5
  • 60
    • 0033584234 scopus 로고    scopus 로고
    • Freshly isolated Peyer's patch, but not spleen, dendritic cells produce interleukin-10 and induce the differentiation of T helper type 2 cells
    • Iwasaki, A. and Kelsall, B. L., Freshly isolated Peyer's patch, but not spleen, dendritic cells produce interleukin-10 and induce the differentiation of T helper type 2 cells, J. Exp. Med., 190, 229-239, 1999.
    • (1999) J. Exp. Med. , vol.190 , pp. 229-239
    • Iwasaki, A.1    Kelsall, B.L.2
  • 62
    • 0002287970 scopus 로고    scopus 로고
    • Ontogeny of the intestinal flora
    • Sanderson, I. R. and Walker, W. A., Eds., B.C. Decker, Inc., London, U.K.
    • Adlerberth, I., Hanson, L. A., and Wold, A. E., Ontogeny of the intestinal flora, in Development of the Gastrointestinal Tract, Sanderson, I. R. and Walker, W. A., Eds., B.C. Decker, Inc., London, U.K., 2000, 279-292.
    • (2000) Development of the Gastrointestinal Tract , pp. 279-292
    • Adlerberth, I.1    Hanson, L.A.2    Wold, A.E.3
  • 66
    • 0033598846 scopus 로고    scopus 로고
    • Ligation of intestinal epithelial CD1d induces bioactive IL-10: Critical role of the cytoplasmic tail in autocrine signaling
    • Colgan, S. P., Hershberg, R. M., Furuta, G. T., and Blumberg, R. S., Ligation of intestinal epithelial CD1d induces bioactive IL-10: critical role of the cytoplasmic tail in autocrine signaling, Proc. Natl. Acad. Sci. U.S.A., 96, 13938-13943, 1999.
    • (1999) Proc. Natl. Acad. Sci. U.S.A. , vol.96 , pp. 13938-13943
    • Colgan, S.P.1    Hershberg, R.M.2    Furuta, G.T.3    Blumberg, R.S.4
  • 68
    • 0030858138 scopus 로고    scopus 로고
    • Inflammatory stimuli induce accumulation of MHC class II complexes on dendritic cells
    • Cella, M., Engering, A., Pinet, V., Pieters, J., and Lanzavecchia, A., Inflammatory stimuli induce accumulation of MHC class II complexes on dendritic cells, Nature, 388, 782-787, 1997.
    • (1997) Nature , vol.388 , pp. 782-787
    • Cella, M.1    Engering, A.2    Pinet, V.3    Pieters, J.4    Lanzavecchia, A.5
  • 70
    • 0028179886 scopus 로고
    • Regulation of immunostimulatory function and costimulatory molecule (B7-1 and B7-2) expression on murine dendritic cells
    • Larsen, C. P., Ritchie, S. C., Hendrix, R., Linsley, P. S., Hathcock, K. S., Hodes, R. J., Lowry, R. P., and Pearson, T. C., Regulation of immunostimulatory function and costimulatory molecule (B7-1 and B7-2) expression on murine dendritic cells, J. Immunol., 152, 5208-5219, 1994.
    • (1994) J. Immunol. , vol.152 , pp. 5208-5219
    • Larsen, C.P.1    Ritchie, S.C.2    Hendrix, R.3    Linsley, P.S.4    Hathcock, K.S.5    Hodes, R.J.6    Lowry, R.P.7    Pearson, T.C.8
  • 71
    • 0031008078 scopus 로고    scopus 로고
    • Maturation of Peyer's patch dendritic cells in vitro upon stimulation via cytokines or CD40 triggering
    • Ruedl, C. and Hubele, S., Maturation of Peyer's patch dendritic cells in vitro upon stimulation via cytokines or CD40 triggering, Eur. J. Immunol., 27, 1325-1330, 1997.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 1325-1330
    • Ruedl, C.1    Hubele, S.2
  • 72
    • 0000060327 scopus 로고    scopus 로고
    • In vivo microbial stimulation induces rapid CD40 ligand-independent production of interleukin-12 by dendritic cells and their redistribution to T-cell areas
    • Reis e Sousa, C., Hieny, S., Scharton-Kersten, T., Jankovic, D., Charest, H., Germain, R. N., and Sher, A., In vivo microbial stimulation induces rapid CD40 ligand-independent production of interleukin-12 by dendritic cells and their redistribution to T-cell areas, J. Exp. Med., 186, 1819-1829, 1997.
    • (1997) J. Exp. Med. , vol.186 , pp. 1819-1829
    • Reis E Sousa, C.1    Hieny, S.2    Scharton-Kersten, T.3    Jankovic, D.4    Charest, H.5    Germain, R.N.6    Sher, A.7
  • 73
    • 0030586611 scopus 로고    scopus 로고
    • Dendritic cells can present antigen in vivo in a tolerogenic or immunogenic fashion
    • Finkelman, F. D., Lees, A., Birnbaum, R., Cause, W. C., and Morris, S. C., Dendritic cells can present antigen in vivo in a tolerogenic or immunogenic fashion, J. Immunol., 157, 1406-1414, 1996.
    • (1996) J. Immunol. , vol.157 , pp. 1406-1414
    • Finkelman, F.D.1    Lees, A.2    Birnbaum, R.3    Cause, W.C.4    Morris, S.C.5
  • 74
    • 0032526346 scopus 로고    scopus 로고
    • Expanding dendritic cells in vivo enhances the induction of oral tolerance
    • Viney, J. L., Mowat, A. M., O'Malley, J. M., Williamson, E., and Fanger, N., Expanding dendritic cells in vivo enhances the induction of oral tolerance, J. Immunol., 160, 5815-5825, 1998.
    • (1998) J. Immunol. , vol.160 , pp. 5815-5825
    • Viney, J.L.1    Mowat, A.M.2    O'Malley, J.M.3    Williamson, E.4    Fanger, N.5
  • 75
    • 0033213958 scopus 로고    scopus 로고
    • Modulating dendritic cells to optimize mucosal immunization protocols
    • Williamson, E., Westrich, G. M., and Viney, J. L., Modulating dendritic cells to optimize mucosal immunization protocols, J. Immunol., 163, 3558-3675, 1999.
    • (1999) J. Immunol. , vol.163 , pp. 3558-3675
    • Williamson, E.1    Westrich, G.M.2    Viney, J.L.3
  • 77
    • 0033562987 scopus 로고    scopus 로고
    • IL-1 is an effective adjuvant for mucosal and systemic immune responses when coadministered with protein immunogens
    • Staats, H. F. and Ennis, Jr., F. A., IL-1 is an effective adjuvant for mucosal and systemic immune responses when coadministered with protein immunogens, J. Immunol., 162, 6141-6147, 1999.
    • (1999) J. Immunol. , vol.162 , pp. 6141-6147
    • Staats, H.F.1    Ennis F.A., Jr.2
  • 78
    • 0009487243 scopus 로고    scopus 로고
    • A helminth-induced mucosal Th2 response alters nonresponsiveness to oral administration of a soluble antigen
    • Shi, H. N., Ingui, C. J., Dodge, I., and Nagler-Anderson, C., A helminth-induced mucosal Th2 response alters nonresponsiveness to oral administration of a soluble antigen, J. Immunol., 160, 2449-2455, 1998.
    • (1998) J. Immunol. , vol.160 , pp. 2449-2455
    • Shi, H.N.1    Ingui, C.J.2    Dodge, I.3    Nagler-Anderson, C.4
  • 79
    • 0021400365 scopus 로고
    • The site selected by the larvae of heligmosomoides polygyrus
    • Sukhdeo, M. V. K., O'Grady, R. T., and Hsu, S. C., The site selected by the larvae of Heligmosomoides polygyrus, J. Helminthol., 58, 19-23, 1984.
    • (1984) J. Helminthol. , vol.58 , pp. 19-23
    • Sukhdeo, M.V.K.1    O'Grady, R.T.2    Hsu, S.C.3
  • 81
    • 0033523689 scopus 로고    scopus 로고
    • Tumor necrosis factor a is a critical component of interleukin-13-mediated protective T helper cell type 2 responses during helminth infection
    • Artis, D., Humphreys, N. E., Bancroft, A. J., Rothwell, N. J., Potten, C. S., and Grencis, R. K., Tumor necrosis factor a is a critical component of interleukin-13-mediated protective T helper cell type 2 responses during helminth infection, J. Exp. Med., 190, 953-962, 1999.
    • (1999) J. Exp. Med. , vol.190 , pp. 953-962
    • Artis, D.1    Humphreys, N.E.2    Bancroft, A.J.3    Rothwell, N.J.4    Potten, C.S.5    Grencis, R.K.6
  • 82
    • 0031965469 scopus 로고    scopus 로고
    • A natural immunological adjuvant enhances T-cell clonal expansion through a CD28-dependent, interleukin (IL)-2-independent mechanism
    • Khoruts, A., Mondino, A., Pape, K. A., Reiner, S. L., and Jenkins, M. K., A natural immunological adjuvant enhances T-cell clonal expansion through a CD28-dependent, interleukin (IL)-2-independent mechanism, J. Exp. Med., 187, 225-236, 1998.
    • (1998) J. Exp. Med. , vol.187 , pp. 225-236
    • Khoruts, A.1    Mondino, A.2    Pape, K.A.3    Reiner, S.L.4    Jenkins, M.K.5
  • 83
    • 0030666222 scopus 로고    scopus 로고
    • Innate immunity: The virtues of a nonclonal system of recognition
    • Medzhitov, R. and Janeway, Jr., C. A., Innate immunity: the virtues of a nonclonal system of recognition, Cell, 91, 295-298, 1997.
    • (1997) Cell , vol.91 , pp. 295-298
    • Medzhitov, R.1    Janeway C.A., Jr.2
  • 84
    • 0032209286 scopus 로고    scopus 로고
    • CpG DNA is a potent enhancer of systemic and mucosal immune responses against hepatitis B surface antigen with intranasal administration to mice
    • McCluskie, M. J. and Davies, H. L., CpG DNA is a potent enhancer of systemic and mucosal immune responses against hepatitis B surface antigen with intranasal administration to mice, J. Immunol., 161, 4463-4466, 1998.
    • (1998) J. Immunol. , vol.161 , pp. 4463-4466
    • McCluskie, M.J.1    Davies, H.L.2
  • 85
    • 0033592748 scopus 로고    scopus 로고
    • The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens
    • Underbill, D. M., Ozinsky, A., Hajjar, A. H., Stevens, A., Wilson, C. B., Bassetti, M., and Aderem, A., The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens, Nature, 401, 811-815, 1999.
    • (1999) Nature , vol.401 , pp. 811-815
    • Underbill, D.M.1    Ozinsky, A.2    Hajjar, A.H.3    Stevens, A.4    Wilson, C.B.5    Bassetti, M.6    Aderem, A.7
  • 86
    • 0030734860 scopus 로고    scopus 로고
    • Role of lipopolysaccharide in signaling to subepithelial polymorphonuclear leukocytes
    • Beatty, W. L. and Sansonetti, P. J., Role of lipopolysaccharide in signaling to subepithelial polymorphonuclear leukocytes, Infect. Immunity, 65, 4395-4404, 1997.
    • (1997) Infect. Immunity , vol.65 , pp. 4395-4404
    • Beatty, W.L.1    Sansonetti, P.J.2
  • 87
    • 0034650930 scopus 로고    scopus 로고
    • Lipopolysaccharide activates distinct signaling pathways in intestinal epithelial cell lines expressing Toll-like receptors
    • Cario, E., Rosenberg, I. M., Brandwein, S. L., Beck, P. L., Reinecker, H.-C., and Podolsky, D. K., Lipopolysaccharide activates distinct signaling pathways in intestinal epithelial cell lines expressing Toll-like receptors, J. Immunol., 164, 966-972, 2000.
    • (2000) J. Immunol. , vol.164 , pp. 966-972
    • Cario, E.1    Rosenberg, I.M.2    Brandwein, S.L.3    Beck, P.L.4    Reinecker, H.-C.5    Podolsky, D.K.6
  • 88
    • 0031954425 scopus 로고    scopus 로고
    • Alteration of gene expression by intestinal epithelial cells precedes colitis in interleukin-2 deficient mice
    • Meijssen, M. A., Brandwein, S. L., Reinecker, H. C., Bhan, A. K., and Podolsky, D. K., Alteration of gene expression by intestinal epithelial cells precedes colitis in interleukin-2 deficient mice, Am. J. Physiol., 274, G472-G478, 1998.
    • (1998) Am. J. Physiol. , vol.274
    • Meijssen, M.A.1    Brandwein, S.L.2    Reinecker, H.C.3    Bhan, A.K.4    Podolsky, D.K.5
  • 89
    • 0013646799 scopus 로고    scopus 로고
    • The role of endogenous luminal bacteria and bacterial products in the pathogenesis of experimental enterocolitis and systemic inflammation
    • Academic Press, San Diego, CA
    • Sartor, R. B., The role of endogenous luminal bacteria and bacterial products in the pathogenesis of experimental enterocolitis and systemic inflammation, in Essentials of Mucosal Immunology, Academic Press, San Diego, CA, 1996, 307-320.
    • (1996) Essentials of Mucosal Immunology , pp. 307-320
    • Sartor, R.B.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.