-
1
-
-
0033179892
-
Immune recognition of foreign DNA: A cure for bioterrorism?
-
Klinman, D. M., Verthelyi, D., Takeshita, F. and Ishii, K. J., Immune recognition of foreign DNA: a cure for bioterrorism? Immunity 1999. 11: 123-129.
-
(1999)
Immunity
, vol.11
, pp. 123-129
-
-
Klinman, D.M.1
Verthelyi, D.2
Takeshita, F.3
Ishii, K.J.4
-
2
-
-
0028931102
-
CpG motifs in bacterial DNA trigger direct B cell activation
-
Krieg, A. M., Yi, A., Matson, S., Waldschmidt, T. J., Bishop, G. A., Teasdale, R., Koretzky, G. A. and Klinman, D. M., CpG motifs in bacterial DNA trigger direct B cell activation. Nature 1995. 374: 546-548.
-
(1995)
Nature
, vol.374
, pp. 546-548
-
-
Krieg, A.M.1
Yi, A.2
Matson, S.3
Waldschmidt, T.J.4
Bishop, G.A.5
Teasdale, R.6
Koretzky, G.A.7
Klinman, D.M.8
-
3
-
-
0029984358
-
CpG motifs expressed by bacterial DNA rapidly induce lymphocytes to secrete IL-6, IL-12 and IFNγ
-
Klinman, D. M., Yi, A., Beaucage, S. L., Conover, J. and Krieg, A. M., CpG motifs expressed by bacterial DNA rapidly induce lymphocytes to secrete IL-6, IL-12 and IFNγ. Proc. Natl. Acad. Sci. USA 1996. 93: 2879-2883.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 2879-2883
-
-
Klinman, D.M.1
Yi, A.2
Beaucage, S.L.3
Conover, J.4
Krieg, A.M.5
-
4
-
-
0030764558
-
Immunostimulatory DNA sequences function as T helper-1 promoting adjuvants
-
Roman, M., Martin-Orozco, E., Goodman, J. S., Nguyen, M., Sato, Y., Ronaghy, A., Kornbluth, R. S., Richman, D. D., Carson, D. A. and Raz, E., Immunostimulatory DNA sequences function as T helper-1 promoting adjuvants. Nature Medicine 1997. 3: 849-854.
-
(1997)
Nature Medicine
, vol.3
, pp. 849-854
-
-
Roman, M.1
Martin-Orozco, E.2
Goodman, J.S.3
Nguyen, M.4
Sato, Y.5
Ronaghy, A.6
Kornbluth, R.S.7
Richman, D.D.8
Carson, D.A.9
Raz, E.10
-
5
-
-
0030816325
-
Macrophages sense pathogens via DNA motifs: Induction of tumor necrosis factor-a-mediated shock
-
Sparwasser, T., Miethke, T., Lipford, G., Erdmann, A., Hacker, H., Heeg, K. and Wagner, H., Macrophages sense pathogens via DNA motifs: induction of tumor necrosis factor-a-mediated shock. Eur. J. Immunol. 1997. 27: 1671-1679.
-
(1997)
Eur. J. Immunol.
, vol.27
, pp. 1671-1679
-
-
Sparwasser, T.1
Miethke, T.2
Lipford, G.3
Erdmann, A.4
Hacker, H.5
Heeg, K.6
Wagner, H.7
-
6
-
-
0026464967
-
DNA from bacteria, but not vertebrates, induces interferons, activate NK cells and inhibits tumor growth
-
Yamamoto, S., Yamamoto, T., Shimada, S., Kuramoto, E., Yano, O., Kataoka, T. and Tokunaga, T., DNA from bacteria, but not vertebrates, induces interferons, activate NK cells and inhibits tumor growth. Microbiol. Immunol. 1992. 36: 983-997.
-
(1992)
Microbiol. Immunol.
, vol.36
, pp. 983-997
-
-
Yamamoto, S.1
Yamamoto, T.2
Shimada, S.3
Kuramoto, E.4
Yano, O.5
Kataoka, T.6
Tokunaga, T.7
-
7
-
-
0345120862
-
Oligodeoxynucleotides containing CpG motifs induce IL-12, IL-18 and IFN-γ production in cells from allergic individuals and inhibit IgE synthesis in vitro
-
Bohle, B., Schmid, B. J., Maurer, D., Kraft, D. and Ebner, C., Oligodeoxynucleotides containing CpG motifs induce IL-12, IL-18 and IFN-γ production in cells from allergic individuals and inhibit IgE synthesis in vitro. Eur. J. Immunol. 1999. 29: 2344-2353.
-
(1999)
Eur. J. Immunol.
, vol.29
, pp. 2344-2353
-
-
Bohle, B.1
Schmid, B.J.2
Maurer, D.3
Kraft, D.4
Ebner, C.5
-
8
-
-
0030613651
-
CpG oligodeoxynucleotides act as adjuvants that switch on T helper (Th1) immunity
-
Chu, R. S., Targoni, O. S., Krieg, A. M., Lehmann, P. V. and Harding, C. V. CpG Oligodeoxynucleotides act as adjuvants that switch on T helper (Th1) immunity. J. Exp. Med. 1997. 186: 1623-1631.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 1623-1631
-
-
Chu, R.S.1
Targoni, O.S.2
Krieg, A.M.3
Lehmann, P.V.4
Harding, C.V.5
-
9
-
-
0032534602
-
Immunostimulatory DNA sequences inhibit IL-5, eosinophilic inflammation, and airway hyperresponsiveness in mice
-
Broide, D., Schwarze, J., Tighe, H., Gifford, T., Nguyen, M. D., Malek, S., Van Uden, J., Martin, E., Gelfand, E. W. and Raz, E., Immunostimulatory DNA sequences inhibit IL-5, eosinophilic inflammation, and airway hyperresponsiveness in mice. J Immunol 1998. 161: 7054-7062.
-
(1998)
J Immunol
, vol.161
, pp. 7054-7062
-
-
Broide, D.1
Schwarze, J.2
Tighe, H.3
Gifford, T.4
Nguyen, M.D.5
Malek, S.6
Van Uden, J.7
Martin, E.8
Gelfand, E.W.9
Raz, E.10
-
10
-
-
0032168355
-
CpG DNA induces sustained IL-12 expression in vivo and resistance to Listeria monocytogenes challenge
-
Krieg, A. M., Homan, L. L., Yi, A. K. and Harty, J. T., CpG DNA induces sustained IL-12 expression in vivo and resistance to Listeria monocytogenes challenge. J. Immunol. 1998. 161: 2428-2434.
-
(1998)
J. Immunol.
, vol.161
, pp. 2428-2434
-
-
Krieg, A.M.1
Homan, L.L.2
Yi, A.K.3
Harty, J.T.4
-
11
-
-
0030955249
-
Immunostimulatory oligodeoxynucleotides containing the CpG motif are effective as immune adjuvants in tumor antigen immunization
-
Weiner, G. J., Liu, H. M., Wooldridge, J. E., Dahle, C. E. and Krieg, A. M. Immunostimulatory oligodeoxynucleotides containing the CpG motif are effective as immune adjuvants in tumor antigen immunization. Proc. Natl. Acad. Sci. USA 1997. 94: 10833-10837.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 10833-10837
-
-
Weiner, G.J.1
Liu, H.M.2
Wooldridge, J.E.3
Dahle, C.E.4
Krieg, A.M.5
-
12
-
-
0032521881
-
CpG oligodeoxynucleotides trigger protective and curative Th1 responses in lethal murine Leishmaniasis
-
Zimmermann, S., Egeter, O., Hausmann, S., Lipford, G. B., Rocken, M., Wagner, H. and Heeg, K., CpG oligodeoxynucleotides trigger protective and curative Th1 responses in lethal murine Leishmaniasis. J. Immunol 1998. 160: 3627-3630.
-
(1998)
J. Immunol
, vol.160
, pp. 3627-3630
-
-
Zimmermann, S.1
Egeter, O.2
Hausmann, S.3
Lipford, G.B.4
Rocken, M.5
Wagner, H.6
Heeg, K.7
-
13
-
-
0032521274
-
Modulation of airway inflammation by CpG oligodeoxynucleotides in a murine model of asthma
-
Kline, J. N., Waldschmidt, T. J., Businga, T. R., Lemish, J. E., Weinstock, J. V., Thorne, P. S. and Krieg, A. M., Modulation of airway inflammation by CpG oligodeoxynucleotides in a murine model of asthma. J. Immunol. 1998. 160: 2555-2559.
-
(1998)
J. Immunol.
, vol.160
, pp. 2555-2559
-
-
Kline, J.N.1
Waldschmidt, T.J.2
Businga, T.R.3
Lemish, J.E.4
Weinstock, J.V.5
Thorne, P.S.6
Krieg, A.M.7
-
14
-
-
0033536013
-
Immunostimulatory oligodeoxynucleotides promote protective immunity and provide systemic therapy for leishmaniasis via IL-12 and IFNg dependent mechanisms
-
Walker, P. S., Scharton-Kersten, T., Krieg, A. M., Love-Homan, L., Rowton, E. D., Udey, M. C. and Vogel, J. C., Immunostimulatory oligodeoxynucleotides promote protective immunity and provide systemic therapy for leishmaniasis via IL-12 and IFNg dependent mechanisms. Proc. Natl. Acad. Sci. U. S. A. 1999. 96: 6970-6975.
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 6970-6975
-
-
Walker, P.S.1
Scharton-Kersten, T.2
Krieg, A.M.3
Love-Homan, L.4
Rowton, E.D.5
Udey, M.C.6
Vogel, J.C.7
-
15
-
-
0030239828
-
Induction of NK activity in murine and human cells by CpG motifs in oligodeoxynucleotides and bacterial DNA
-
Ballas, Z. D., Rasmussen, W. L. and Krieg, A. M., Induction of NK activity in murine and human cells by CpG motifs in oligodeoxynucleotides and bacterial DNA. J. Immunol. 1996. 157: 1840-1847.
-
(1996)
J. Immunol.
, vol.157
, pp. 1840-1847
-
-
Ballas, Z.D.1
Rasmussen, W.L.2
Krieg, A.M.3
-
16
-
-
0028970060
-
Interleukin-12: A proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity
-
Trinchieri, G., Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity. Annu. Rev. Immunol. 1995. 13: 251-276.
-
(1995)
Annu. Rev. Immunol.
, vol.13
, pp. 251-276
-
-
Trinchieri, G.1
-
17
-
-
0029143632
-
Regulation of interleukin 12 p40 expression through an NF-κB half-site
-
Murphy, T. L., Cleveland, M. G., Kulesza, P., Magram, J. and Murphy, K. M., Regulation of interleukin 12 p40 expression through an NF-κB half-site. Mol. Cell Biol 1995. 15: 5258-5267.
-
(1995)
Mol. Cell Biol
, vol.15
, pp. 5258-5267
-
-
Murphy, T.L.1
Cleveland, M.G.2
Kulesza, P.3
Magram, J.4
Murphy, K.M.5
-
18
-
-
0030872393
-
Multiple control elements mediate activation of the murine and human interleukin 12 p40 promoters: Evidence of functional synergy between C/EBP and Rel proteins
-
Plevy, S. E., Gemberling, J. H. M., Hsu, S., Dorner, A. J. and Smale, S. T., Multiple control elements mediate activation of the murine and human interleukin 12 p40 promoters: evidence of functional synergy between C/EBP and Rel proteins. Mol. Cell. Biol. 1997. 17: 4572-4588.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 4572-4588
-
-
Plevy, S.E.1
Gemberling, J.H.M.2
Hsu, S.3
Dorner, A.J.4
Smale, S.T.5
-
19
-
-
0032513227
-
Synergistic regulation of the human interleukin-12 p40 promoter by NF-κB and Ets transcription factors in Epstein-Barr virus-transformed B cells and macrophages
-
Gri, G., Savio, D., Trinchieri, G. and Ma, X., Synergistic regulation of the human interleukin-12 p40 promoter by NF-κB and Ets transcription factors in Epstein-Barr virus-transformed B cells and macrophages. Journal of Biological Chemistry 1998. 273: 6431-6438.
-
(1998)
Journal of Biological Chemistry
, vol.273
, pp. 6431-6438
-
-
Gri, G.1
Savio, D.2
Trinchieri, G.3
Ma, X.4
-
20
-
-
0032867015
-
Mechanism and therapeutic applications of immune stimulatory CpG DNA
-
Krieg, A. M., Hartmann, G. and Yi, A., Mechanism and therapeutic applications of immune stimulatory CpG DNA. Pharmacol. Ther. 1999. 84: 113-120.
-
(1999)
Pharmacol. Ther.
, vol.84
, pp. 113-120
-
-
Krieg, A.M.1
Hartmann, G.2
Yi, A.3
-
21
-
-
0030064148
-
The interleukin 12 p40 gene promoter is primed by interferon γ in monocytic cells
-
Ma, X., Chow, J. M., Gri, G., Carra, G., Gerosa, F., Wolf, S. F., Dzialo, R. and Trinchieri, G., The interleukin 12 p40 gene promoter is primed by interferon γ in monocytic cells. J. Exp. Med. 1996. 183: 147-157.
-
(1996)
J. Exp. Med.
, vol.183
, pp. 147-157
-
-
Ma, X.1
Chow, J.M.2
Gri, G.3
Carra, G.4
Gerosa, F.5
Wolf, S.F.6
Dzialo, R.7
Trinchieri, G.8
-
22
-
-
0032525023
-
CpG motifs in bacterial DNA activate leukocytes through the pH-dependent generation of reactive oxygen species
-
Yi, A., Tuetken, R., Redford, T., Waldschmidt, M., Kirsch, J. and Krieg, A. M., CpG motifs in bacterial DNA activate leukocytes through the pH-dependent generation of reactive oxygen species. J. Immunol 1998. 160: 4755-4761.
-
(1998)
J. Immunol
, vol.160
, pp. 4755-4761
-
-
Yi, A.1
Tuetken, R.2
Redford, T.3
Waldschmidt, M.4
Kirsch, J.5
Krieg, A.M.6
-
23
-
-
0032476602
-
CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation
-
Hacker, H., Mischak, H., Miethke, T., Liptay, S., Schmid, R., Sparwasser, T., Heeg, K., Lipford, G. B. and Wagner, H., CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation. EMBO 1998. 17: 6230-6540.
-
(1998)
EMBO
, vol.17
, pp. 6230-6540
-
-
Hacker, H.1
Mischak, H.2
Miethke, T.3
Liptay, S.4
Schmid, R.5
Sparwasser, T.6
Heeg, K.7
Lipford, G.B.8
Wagner, H.9
-
24
-
-
0033151919
-
Differential regulation of the IL-12 p40 promoter and of p40 secretion by CpG DNA and lipopolysaccharide
-
Cowdery, J. S., Boerth, N. J., Norian, L. A., Myung, P. S. and Koretzky, G. A., Differential regulation of the IL-12 p40 promoter and of p40 secretion by CpG DNA and lipopolysaccharide. J. Immunol. 1999. 162: 6770-6775.
-
(1999)
J. Immunol.
, vol.162
, pp. 6770-6775
-
-
Cowdery, J.S.1
Boerth, N.J.2
Norian, L.A.3
Myung, P.S.4
Koretzky, G.A.5
-
25
-
-
0026708394
-
Independent modes of transcriptional activation by the p50 and p65 subunits of NF-kB
-
Fujita, T., Nolan, G. P., Ghosh, S. and Baltimore, D., Independent modes of transcriptional activation by the p50 and p65 subunits of NF-kB. Genes and Dev. 1992. 6: 775-787.
-
(1992)
Genes and Dev.
, vol.6
, pp. 775-787
-
-
Fujita, T.1
Nolan, G.P.2
Ghosh, S.3
Baltimore, D.4
-
26
-
-
0033989756
-
Positive and negative regulatory elements contribute to CpG ODN-mediated regulation of human IL-6 gene expression
-
Takesnita, F., Ishii, K. J., Ueda, A., Ishigatsubo, Y. and Klinman, D. M., Positive and negative regulatory elements contribute to CpG ODN-mediated regulation of human IL-6 gene expression. Eur. J. Immunol. 2000. 30: 108-116.
-
(2000)
Eur. J. Immunol.
, vol.30
, pp. 108-116
-
-
Takesnita, F.1
Ishii, K.J.2
Ueda, A.3
Ishigatsubo, Y.4
Klinman, D.M.5
-
27
-
-
0032563121
-
Positive regulation of the human macrophage stimulating protein gene transcription
-
Ueda, A., Takeshita, F., Yamashiro, S. and Yoshimura, T. Positive regulation of the human macrophage stimulating protein gene transcription. J. Biol. Chem. 1998. 273: 19339-19347.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 19339-19347
-
-
Ueda, A.1
Takeshita, F.2
Yamashiro, S.3
Yoshimura, T.4
-
28
-
-
0030707615
-
Transcriptional regulation of the human monocyte chemoattractant protein-1 gene
-
Ueda, A., Ishigatsubo, Y., Okubo, T. and Yoshimura, T., Transcriptional regulation of the human monocyte chemoattractant protein-1 gene. J. Biol. Chem. 1997. 272: 31092-31099.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 31092-31099
-
-
Ueda, A.1
Ishigatsubo, Y.2
Okubo, T.3
Yoshimura, T.4
|