Positive and negative regulatory elements contribute to CpG oligonucleotide-mediated regulation of human IL-6 gene expression

European Journal of Immunology

Volumn 30, Issue 1, 2000, Pages 108-116

  Takeshita, Fumihiko ^a   Ishii, Ken J ^a   Ueda, Atsuhisa ^b   Ishigatsubo, Yoshiaki ^b   Klinman, Dennis M ^a,c  

^a CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

^b YOKOHAMA CITY UNIVERSITY   (Japan)

^c CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

CpG oligodeoxynucleotide; IL 6; Regulation

Indexed keywords

BINDING PROTEIN; INTERLEUKIN 6; OLIGONUCLEOTIDE; REPRESSOR PROTEIN;

ANIMAL CELL; ARTICLE; BINDING SITE; CONTROLLED STUDY; CPG ISLAND; EPSTEIN BARR VIRUS; GENE EXPRESSION REGULATION; GENE INDUCTION; MOUSE; MYELOMA CELL; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; REGULATOR GENE; SITE DIRECTED MUTAGENESIS; TUMOR SUPPRESSOR GENE;

CCAAT-ENHANCER-BINDING PROTEINS; DINUCLEOSIDE PHOSPHATES; DNA; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKIN-6; NF-KAPPA B; NUCLEAR PROTEINS; OLIGONUCLEOTIDES; PROMOTER REGIONS (GENETICS); TUMOR CELLS, CULTURED;

EID: 0033989756     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200001)30:1<108::AID-IMMU108>3.0.CO;2-4     Document Type: Article

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