-
1
-
-
0342738233
-
The Ras superfamily of small GTP binding proteins
-
Downward J. The Ras superfamily of small GTP binding proteins. Trends Biochem. Sci. 57:1990;449-477.
-
(1990)
Trends Biochem. Sci.
, vol.57
, pp. 449-477
-
-
Downward, J.1
-
2
-
-
0024406286
-
All Ras proteins are polyisoprenylated but only some are palmyitoylated
-
Hanckock J.C., Paterson H.F., Marshall C.J. All Ras proteins are polyisoprenylated but only some are palmyitoylated. Cell. 9:1989;1167-1177.
-
(1989)
Cell
, vol.9
, pp. 1167-1177
-
-
Hanckock, J.C.1
Paterson, H.F.2
Marshall, C.J.3
-
3
-
-
0025310575
-
Refined crysta, structure of the triphosphate conformation of the H-Ras p21 at 1, 35A resolution: Implication for the mechanism of GTP hydrolysis
-
Pai E.F., Krengel U., Petsko G.A., Goody R.S., Kabsch W., Wittinghofer A. Refined crysta, structure of the triphosphate conformation of the H-Ras p21 at 1, 35A resolution: implication for the mechanism of GTP hydrolysis. EMBO J. 16:1990;2351-2359.
-
(1990)
EMBO J.
, vol.16
, pp. 2351-2359
-
-
Pai, E.F.1
Krengel, U.2
Petsko, G.A.3
Goody, R.S.4
Kabsch, W.5
Wittinghofer, A.6
-
4
-
-
0025740753
-
The structure of Ras protein: A model for universal molecular switch
-
Wittinghofer A., Pai E.F. The structure of Ras protein: a model for universal molecular switch. Trends in Biochem. Sci. 21:1991;382-387.
-
(1991)
Trends in Biochem. Sci.
, vol.21
, pp. 382-387
-
-
Wittinghofer, A.1
Pai, E.F.2
-
5
-
-
0030464444
-
How Ras-related proteins talk to their effectors
-
Wittinghofer A., Nassar N. How Ras-related proteins talk to their effectors. Trends Biochem. Sci. 394:1996;488-491.
-
(1996)
Trends Biochem. Sci.
, vol.394
, pp. 488-491
-
-
Wittinghofer, A.1
Nassar, N.2
-
7
-
-
0023619575
-
A cytoplasmic protein stimulates normal H-Ras p21 GTPase but does not affect oncogenic mutants
-
Trahey M., McCormick F. A cytoplasmic protein stimulates normal H-Ras p21 GTPase but does not affect oncogenic mutants. Science. 277:1987;542-545.
-
(1987)
Science
, vol.277
, pp. 542-545
-
-
Trahey, M.1
McCormick, F.2
-
8
-
-
0030772378
-
The Ras-RasGAP complex: Structural basis for GTPase activation and its loss in oncogenic Ras mutants
-
Scheffzek K., Ahmadian M.R., Kabsch W., Wiesmüller L., Lautwein A., Schmitz F., Wittinghofer A. The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants. Science. 349:1997;333-338.
-
(1997)
Science
, vol.349
, pp. 333-338
-
-
Scheffzek, K.1
Ahmadian, M.R.2
Kabsch, W.3
Wiesmüller, L.4
Lautwein, A.5
Schmitz, F.6
Wittinghofer, A.7
-
9
-
-
0026026818
-
The GTPase superfamily: Conserved structure and molecular mechanism
-
Bourne H.R., Sanders D., Mc Cormick F. The GTPase superfamily: conserved structure and molecular mechanism. Nature. 389:1991;117-127.
-
(1991)
Nature
, vol.389
, pp. 117-127
-
-
Bourne, H.R.1
Sanders, D.2
Mc Cormick, F.3
-
10
-
-
0030722725
-
The arginine finger strikes again
-
Bourne H.R. The arginine finger strikes again. Nature. 387:1997;673-674.
-
(1997)
Nature
, vol.387
, pp. 673-674
-
-
Bourne, H.R.1
-
11
-
-
0030992838
-
Toxin-induced activation of the G-protein p21 Rho by deamidation of glutamine
-
Flatau G., Lemichez E., Gauthier M., Chardin P., Paris S., Fiorentini C., Boquet P. Toxin-induced activation of the G-protein p21 Rho by deamidation of glutamine. Nature. 387:1997;729-733.
-
(1997)
Nature
, vol.387
, pp. 729-733
-
-
Flatau, G.1
Lemichez, E.2
Gauthier, M.3
Chardin, P.4
Paris, S.5
Fiorentini, C.6
Boquet, P.7
-
12
-
-
0030610785
-
Rho gln 63 is deamidated by Escherichia coli cytotoxic necrotizing factor 1
-
Schmidt G., Sehr P., Wilm M., Selzer J., Mann M., Aktories K. Rho gln 63 is deamidated by Escherichia coli cytotoxic necrotizing factor 1. Nature. 8:1997;725-729.
-
(1997)
Nature
, vol.8
, pp. 725-729
-
-
Schmidt, G.1
Sehr, P.2
Wilm, M.3
Selzer, J.4
Mann, M.5
Aktories, K.6
-
13
-
-
0024449589
-
The mammalian G-protein RhoC is ADP-ribosylated by Clostridium botulinum exoenzyme C3 and affects actin microfilament in Vero cells
-
Chardin P., Boquet P., Madaule P., Popoff M.R., Rubin E.J., Gill D.M. The mammalian G-protein RhoC is ADP-ribosylated by Clostridium botulinum exoenzyme C3 and affects actin microfilament in Vero cells. EMBO J. 70:1989;1087-1092.
-
(1989)
EMBO J.
, vol.70
, pp. 1087-1092
-
-
Chardin, P.1
Boquet, P.2
Madaule, P.3
Popoff, M.R.4
Rubin, E.J.5
Gill, D.M.6
-
14
-
-
0026778133
-
The small GTP-binding protein Rho regulates the assembly of focal adhesion and actin stress fibres in response to growth factor
-
Ridley A.J., Hall A. The small GTP-binding protein Rho regulates the assembly of focal adhesion and actin stress fibres in response to growth factor. Cell. 70:1992;389-399.
-
(1992)
Cell
, vol.70
, pp. 389-399
-
-
Ridley, A.J.1
Hall, A.2
-
15
-
-
0026654125
-
The small GTP-binding protein Rac regulates growth factor-induced membrane ruffling
-
Ridley A.J., Paterson H.F., Johnston C.L., Dickmann O., Hall A. The small GTP-binding protein Rac regulates growth factor-induced membrane ruffling. Cell. 81:1992;401-410.
-
(1992)
Cell
, vol.81
, pp. 401-410
-
-
Ridley, A.J.1
Paterson, H.F.2
Johnston, C.L.3
Dickmann, O.4
Hall, A.5
-
16
-
-
0002699695
-
Rho, Rac and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers lamellipodia and filopodia
-
Nobes C.D., Hall A. Rho, Rac and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers lamellipodia and filopodia. Cell. 16:1995;1-20.
-
(1995)
Cell
, vol.16
, pp. 1-20
-
-
Nobes, C.D.1
Hall, A.2
-
17
-
-
0029779004
-
The GTPase-activating protein n-chimaerin cooperates with Rac1 and Cdc42Hs to induce the formation of lamellipodia and filopodia
-
Kozma R., Ahmed S., Best A., Lim L. The GTPase-activating protein n-chimaerin cooperates with Rac1 and Cdc42Hs to induce the formation of lamellipodia and filopodia. Mol. Cell Biol. 283:1996;5069-5080.
-
(1996)
Mol. Cell Biol.
, vol.283
, pp. 5069-5080
-
-
Kozma, R.1
Ahmed, S.2
Best, A.3
Lim, L.4
-
19
-
-
0033615966
-
Rac downregulates Rho activity: Reciprocal balance between both GTPases determines cellular morphology and migratory behaviour
-
Sander E.E., Ten Klooster J.P., Van Delft S., Van Der Kammen R.A., Collard J.G. Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behaviour. J. Cell Biol. 15:1999;1009-1021.
-
(1999)
J. Cell Biol.
, vol.15
, pp. 1009-1021
-
-
Sander, E.E.1
Ten Klooster, J.P.2
Van Delft, S.3
Van Der Kammen, R.A.4
Collard, J.G.5
-
20
-
-
9244257348
-
Rho-associated kinase, a novel serinethreonine kinase, as putative target for the small GTP-binding protein Rho
-
Matsui T., Amano M., Yamamoto T., Chihara K., Nakafuka M., Ito M., Nakano T., Okawa K., Iwamatsu A., Kaibuchi K. Rho-associated kinase, a novel serinethreonine kinase, as putative target for the small GTP-binding protein Rho. EMBO J. 15:1996;2208-2216.
-
(1996)
EMBO J.
, vol.15
, pp. 2208-2216
-
-
Matsui, T.1
Amano, M.2
Yamamoto, T.3
Chihara, K.4
Nakafuka, M.5
Ito, M.6
Nakano, T.7
Okawa, K.8
Iwamatsu, A.9
Kaibuchi, K.10
-
21
-
-
9244220646
-
The small GTP-binding protein Rho binds to and activates a 160 kDa serthr protein kinase homologous to myotonic dystrophy kinase
-
Ishizaki T., Mackawa M., Fujisawa K., Okawa K., Iwamatsu A., Fujita A., Watanabe N., Saito Y., Kakizuka Y., Morii N., Narumiya S. The small GTP-binding protein Rho binds to and activates a 160 kDa serthr protein kinase homologous to myotonic dystrophy kinase. EMBO J. 273:1996;1885-1893.
-
(1996)
EMBO J.
, vol.273
, pp. 1885-1893
-
-
Ishizaki, T.1
Mackawa, M.2
Fujisawa, K.3
Okawa, K.4
Iwamatsu, A.5
Fujita, A.6
Watanabe, N.7
Saito, Y.8
Kakizuka, Y.9
Morii, N.10
Narumiya, S.11
-
22
-
-
9444242736
-
Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)
-
Kimura K., Ito M., Amano M., Chihara K., Fukuta Y., Nakafuku M., Yamamori B., Feng J., Nakano T., Okawa K., Iwamatsu A., Kaibuchi I. Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase). Science. 6:1996;245-247.
-
(1996)
Science
, vol.6
, pp. 245-247
-
-
Kimura, K.1
Ito, M.2
Amano, M.3
Chihara, K.4
Fukuta, Y.5
Nakafuku, M.6
Yamamori, B.7
Feng, J.8
Nakano, T.9
Okawa, K.10
Iwamatsu, A.11
Kaibuchi, I.12
-
23
-
-
0029995797
-
Rho-stimulated contractility drives the formation of stress fibers and focal adhesions
-
Chrzanowska-Wodnicka M., Burridge K. Rho-stimulated contractility drives the formation of stress fibers and focal adhesions. J. Cell Biol. 393:1996;1403-1415.
-
(1996)
J. Cell Biol.
, vol.393
, pp. 1403-1415
-
-
Chrzanowska-Wodnicka, M.1
Burridge, K.2
-
24
-
-
0032565962
-
Regulation of actin dynamics through phophorylation of cofilin by Lim-kinase
-
Arber S., Barbayannis F.A., Hanser M., Schneider C., Stanyon C.A., Bernard O., Caroni P. Regulation of actin dynamics through phophorylation of cofilin by Lim-kinase. Nature. 99:1998;805-809.
-
(1998)
Nature
, vol.99
, pp. 805-809
-
-
Arber, S.1
Barbayannis, F.A.2
Hanser, M.3
Schneider, C.4
Stanyon, C.A.5
Bernard, O.6
Caroni, P.7
-
25
-
-
0033601075
-
Phosphatidyil 4-phosphate 5-kinase α is a downstream effector of the small G protein ARF6 in membrane ruffle formation
-
Honda A., Nogami M., Yokoseki T., Yamasaki M., Nakamura H., Watanabe H., Kawamoto K., Nakayama K., Morris A.J., Frohman M.A., Kanaho Y. Phosphatidyil 4-phosphate 5-kinase α is a downstream effector of the small G protein ARF6 in membrane ruffle formation. Cell. 84:1999;521-532.
-
(1999)
Cell
, vol.84
, pp. 521-532
-
-
Honda, A.1
Nogami, M.2
Yokoseki, T.3
Yamasaki, M.4
Nakamura, H.5
Watanabe, H.6
Kawamoto, K.7
Nakayama, K.8
Morris, A.J.9
Frohman, M.A.10
Kanaho, Y.11
-
26
-
-
0030006284
-
Wiskott-Aldrich syndrome protein, a novel effector for the GTPase Cdc42Hs is implicated in actin polymerization
-
Symons M., Derry J.M., Karlak B., Jiang S., Lemahieu V., Mc Cormick F., Francke U., Abo A. Wiskott-Aldrich syndrome protein, a novel effector for the GTPase Cdc42Hs is implicated in actin polymerization. Cell. 15:1996;723-734.
-
(1996)
Cell
, vol.15
, pp. 723-734
-
-
Symons, M.1
Derry, J.M.2
Karlak, B.3
Jiang, S.4
Lemahieu, V.5
Mc Cormick, F.6
Francke, U.7
Abo, A.8
-
27
-
-
0029815611
-
N-WASP a novel actin-depolymerizing protein, regulates the cortical cytoskeleton rearrangment in a PIP2-dependent manner downstream of tyrosine kinases
-
Miki M., Miura K., Takenawa T.N., Miki M., Miura K., Takenawa T.N. N-WASP a novel actin-depolymerizing protein, regulates the cortical cytoskeleton rearrangment in a PIP2-dependent manner downstream of tyrosine kinases. EMBO J. 391:1996;5326-5335.
-
(1996)
EMBO J.
, vol.391
, pp. 5326-5335
-
-
Miki, M.1
Miura, K.2
Takenawa, T.N.3
Miki, M.4
Miura, K.5
Takenawa, T.N.6
-
28
-
-
0031952518
-
Induction of Filopodia formation by a WASP-related actin-depolymerizing factor N-WASP
-
Miki M., Sasaki T., Takai Y., Takenawa T. Induction of Filopodia formation by a WASP-related actin-depolymerizing factor N-WASP. Nature. 97:1998;93-96.
-
(1998)
Nature
, vol.97
, pp. 93-96
-
-
Miki, M.1
Sasaki, T.2
Takai, Y.3
Takenawa, T.4
-
29
-
-
0033574722
-
The interaction between N-WASP and the Arp33 complex links Cdc42-dependent signals to actin assembly
-
Rohatgi R., Le Ma Miki H., Lopez M., Kirchausen T., Takenawa T., Kirschner M. The interaction between N-WASP and the Arp33 complex links Cdc42-dependent signals to actin assembly. Cell. 87:1999;221-231.
-
(1999)
Cell
, vol.87
, pp. 221-231
-
-
Rohatgi, R.1
Le Ma Miki, H.2
Lopez, M.3
Kirchausen, T.4
Takenawa, T.5
Kirschner, M.6
-
30
-
-
0030298138
-
Rac and Cdc42 induce actin polymerization and G1 cell cycle progression independently of p65PAK and the JNKSAPK MAP kinase cascade
-
Lamarche N., Tapon N., Stower L., Burbelo P.D., Aspenström P., Bridges T., Chan J., Hall A. Rac and Cdc42 induce actin polymerization and G1 cell cycle progression independently of p65PAK and the JNKSAPK MAP kinase cascade. Cell. 81:1996;519-529.
-
(1996)
Cell
, vol.81
, pp. 519-529
-
-
Lamarche, N.1
Tapon, N.2
Stower, L.3
Burbelo, P.D.4
Aspenström, P.5
Bridges, T.6
Chan, J.7
Hall, A.8
-
31
-
-
0029070887
-
Selective activation of the JAK signalling cascade and C-Jun transcriptional activity by the small GTPase Rac and Cdc42
-
Minden A., Lin A., Claret F.X., Abo A., Karin M. Selective activation of the JAK signalling cascade and C-Jun transcriptional activity by the small GTPase Rac and Cdc42. Cell. 270:1995;1147-1157.
-
(1995)
Cell
, vol.270
, pp. 1147-1157
-
-
Minden, A.1
Lin, A.2
Claret, F.X.3
Abo, A.4
Karin, M.5
-
32
-
-
0028875683
-
Cdc42 and PAK-mediated signalling leads to Jun kinase and p38 mitogen-activated protein kinase activation
-
Bagrodia S., Derijard B., Davis J., Cerione R.A. Cdc42 and PAK-mediated signalling leads to Jun kinase and p38 mitogen-activated protein kinase activation. J. Biol. Chem. 81:1995;27995-27998.
-
(1995)
J. Biol. Chem.
, vol.81
, pp. 27995-27998
-
-
Bagrodia, S.1
Derijard, B.2
Davis, J.3
Cerione, R.A.4
-
33
-
-
0029015774
-
The Rho family GTPases RhoA, Rac1 and Cdc42Hs regulate transcriptional activation by SRF
-
Hill C.S., Wynne J., Treisman R. The Rho family GTPases RhoA, Rac1 and Cdc42Hs regulate transcriptional activation by SRF. Cell. 1:1995;1159-1170.
-
(1995)
Cell
, vol.1
, pp. 1159-1170
-
-
Hill, C.S.1
Wynne, J.2
Treisman, R.3
-
34
-
-
0031988007
-
Toxins from anaerobic bacteria: Specificity and molecular mechanisms of action
-
Boquet P., Munro P., Fiorentini C., Just I. Toxins from anaerobic bacteria: specificity and molecular mechanisms of action. Curr. Opin. Microbiol. 34:1998;66-74.
-
(1998)
Curr. Opin. Microbiol.
, vol.34
, pp. 66-74
-
-
Boquet, P.1
Munro, P.2
Fiorentini, C.3
Just, I.4
-
35
-
-
0032874924
-
Towards deciphering the Helicobacter pylori cytotoxin
-
Reyrat J.M., Pelicic V., Papini E., Montecucco C., Rappuoli R., Telford J.L. Towards deciphering the Helicobacter pylori cytotoxin. Mol. Microbiol. 5:1999;197-204.
-
(1999)
Mol. Microbiol.
, vol.5
, pp. 197-204
-
-
Reyrat, J.M.1
Pelicic, V.2
Papini, E.3
Montecucco, C.4
Rappuoli, R.5
Telford, J.L.6
-
36
-
-
0030802038
-
Rho proteins: Targets for bacterial toxins
-
Aktories K. Rho proteins: targets for bacterial toxins. Trends Microbiol. 5:1997;282-288.
-
(1997)
Trends Microbiol.
, vol.5
, pp. 282-288
-
-
Aktories, K.1
-
37
-
-
0031786657
-
Bacterial toxins and the Rho GTP-binding protein: What microbes teach us about cell regulation
-
Fiorentini C., Gauthier M., Donelli G., Boquet P. Bacterial toxins and the Rho GTP-binding protein: what microbes teach us about cell regulation. Cell Death Diff. 264:1998;720-728.
-
(1998)
Cell Death Diff.
, vol.264
, pp. 720-728
-
-
Fiorentini, C.1
Gauthier, M.2
Donelli, G.3
Boquet, P.4
-
38
-
-
0024353843
-
Asparagine residue in the Rho gene product is the modification site for Botulinum ADP-ribosyltransferase
-
Sekine A., Fujiwara M., Narumyia S. Asparagine residue in the Rho gene product is the modification site for Botulinum ADP-ribosyltransferase. J. Biol. Chem. 4:1989;8602-8605.
-
(1989)
J. Biol. Chem.
, vol.4
, pp. 8602-8605
-
-
Sekine, A.1
Fujiwara, M.2
Narumyia, S.3
-
39
-
-
0031226057
-
Crystal structure of RhoAGDP and its functional implications
-
Wei Y., Zhang Y., Derewenda U., Liu X., Minor W., Nakamoto R.K., Somlyo A.V., Somlyo A.P., Derewenda Z.S. Crystal structure of RhoAGDP and its functional implications. Nature Struct. Biol. 31:1997;699-703.
-
(1997)
Nature Struct. Biol.
, vol.31
, pp. 699-703
-
-
Wei, Y.1
Zhang, Y.2
Derewenda, U.3
Liu, X.4
Minor, W.5
Nakamoto, R.K.6
Somlyo, A.V.7
Somlyo, A.P.8
Derewenda, Z.S.9
-
40
-
-
0027102910
-
Copurification of Rho protein and the Rho-GDP dissociation inhibitor from bovine neutrophil cytosol. Effect of phosphoinositides on Rho ADP-ribosylation by the C3 exoenzyme of Clostridium botulinum
-
Bourmeyster N., Stasia M.J., Garin J., Gagnon J., Boquet P., Vignais P. Copurification of Rho protein and the Rho-GDP dissociation inhibitor from bovine neutrophil cytosol. Effect of phosphoinositides on Rho ADP-ribosylation by the C3 exoenzyme of Clostridium botulinum. Biochemistry. 8:1992;12863-12869.
-
(1992)
Biochemistry
, vol.8
, pp. 12863-12869
-
-
Bourmeyster, N.1
Stasia, M.J.2
Garin, J.3
Gagnon, J.4
Boquet, P.5
Vignais, P.6
-
41
-
-
0030721443
-
Inhibition of RhoA translocation and calcium sensitization by in vivo ADP-ribosylation of Rho with the chimeric DC3B
-
Fujihara H., Walker L.A., Gong M.C., Lemichez E., Boquet P., Somlyo A.V., Somlyo A.P. Inhibition of RhoA translocation and calcium sensitization by in vivo ADP-ribosylation of Rho with the chimeric DC3B. Mol. Cell Biol. 375:1997;2437-2447.
-
(1997)
Mol. Cell Biol.
, vol.375
, pp. 2437-2447
-
-
Fujihara, H.1
Walker, L.A.2
Gong, M.C.3
Lemichez, E.4
Boquet, P.5
Somlyo, A.V.6
Somlyo, A.P.7
-
42
-
-
0029054398
-
Glucosylation of Rho proteins by Clostridium difficile toxin B
-
Just I., Selzer J., Wilm M., Von Eichel-Streiber C., Mann M., Aktories K. Glucosylation of Rho proteins by Clostridium difficile toxin B. Nature. 270:1995;500-503.
-
(1995)
Nature
, vol.270
, pp. 500-503
-
-
Just, I.1
Selzer, J.2
Wilm, M.3
Von Eichel-Streiber, C.4
Mann, M.5
Aktories, K.6
-
43
-
-
0029011449
-
The enterotoxin from Clostridium difficile (ToxA) monoglucosylates the Rho proteins
-
Just I., Wilm M., Selzer J., Rex G., Von Eichel-Streiber C., Mann M., Aktories K. The enterotoxin from Clostridium difficile (ToxA) monoglucosylates the Rho proteins. J. Biol. Chem. 271:1995;13932-13936.
-
(1995)
J. Biol. Chem.
, vol.271
, pp. 13932-13936
-
-
Just, I.1
Wilm, M.2
Selzer, J.3
Rex, G.4
Von Eichel-Streiber, C.5
Mann, M.6
Aktories, K.7
-
44
-
-
0029925007
-
Inactivation of Ras by Clostridium sordelli lethal toxin-catalyzed glucosylation
-
Just I., Selzer J., Hofman F., Green G.A., Aktories K. Inactivation of Ras by Clostridium sordelli lethal toxin-catalyzed glucosylation. J. Biol. Chem. 271:1996;10149-10153.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 10149-10153
-
-
Just, I.1
Selzer, J.2
Hofman, F.3
Green, G.A.4
Aktories, K.5
-
45
-
-
15844415779
-
Ras, Rap and Rac small GTP-binding proteins are target for Clostridium sordellii lethal toxin glucosylation
-
Popoff M.R., Chaves-Olarte E., Lemichez E., Von Eichel-Streiber C., Thelestam M., Chardin P., Cussac D., Antonny B., Chavrier P., Flatau G., Boquet P. Ras, Rap and Rac small GTP-binding proteins are target for Clostridium sordellii lethal toxin glucosylation. J. Biol. Chem. 273:1996;10217-10224.
-
(1996)
J. Biol. Chem.
, vol.273
, pp. 10217-10224
-
-
Popoff, M.R.1
Chaves-Olarte, E.2
Lemichez, E.3
Von Eichel-Streiber, C.4
Thelestam, M.5
Chardin, P.6
Cussac, D.7
Antonny, B.8
Chavrier, P.9
Flatau, G.10
Boquet, P.11
-
46
-
-
0032568834
-
Functional consequences of monoglucosylation of Ha-Ras at effector domain amino acid threonine 35
-
Herrmann C., Ahmadian M.R., Hofmann F., Just I. Functional consequences of monoglucosylation of Ha-Ras at effector domain amino acid threonine 35. J. Biol. Chem. 274:1998;16134-16139.
-
(1998)
J. Biol. Chem.
, vol.274
, pp. 16134-16139
-
-
Herrmann, C.1
Ahmadian, M.R.2
Hofmann, F.3
Just, I.4
-
47
-
-
0032831781
-
Monoglucosylation of RhoA at threonine 37 blocks cytosol membrane recycling
-
Genth H., Aktories K., Just I. Monoglucosylation of RhoA at threonine 37 blocks cytosol membrane recycling. J. Biol. Chem. 272:1999;29050-29056.
-
(1999)
J. Biol. Chem.
, vol.272
, pp. 29050-29056
-
-
Genth, H.1
Aktories, K.2
Just, I.3
-
48
-
-
0030891386
-
Localization of the glucosyltransferase activity of Clostridium difficile toxin B to the N-terminal part of the holotoxin
-
Hofmann F., Busch C., Prepens U., Just I., Aktories K. Localization of the glucosyltransferase activity of Clostridium difficile toxin B to the N-terminal part of the holotoxin. J. Biol. Chem. 66:1997;11074-11078.
-
(1997)
J. Biol. Chem.
, vol.66
, pp. 11074-11078
-
-
Hofmann, F.1
Busch, C.2
Prepens, U.3
Just, I.4
Aktories, K.5
-
49
-
-
0031887901
-
Chimeric clostridial cytotoxins: Identification of the N-terminal region involved in protein substrate recognition
-
Hofmann F., Busch C., Aktories K. Chimeric clostridial cytotoxins: identification of the N-terminal region involved in protein substrate recognition. Infect. Immun. 273:1998;1076-1081.
-
(1998)
Infect. Immun.
, vol.273
, pp. 1076-1081
-
-
Hofmann, F.1
Busch, C.2
Aktories, K.3
-
50
-
-
0032584665
-
A common motif of eukaryotic glycosyltransferases is essential for the enzyme activity of large clostridial cytotoxins
-
Busch C., Hofmann F., Selzer J., Munro S., Jeckel D., Aktories K. A common motif of eukaryotic glycosyltransferases is essential for the enzyme activity of large clostridial cytotoxins. J. Biol. Chem. 94:1998;19566-19572.
-
(1998)
J. Biol. Chem.
, vol.94
, pp. 19566-19572
-
-
Busch, C.1
Hofmann, F.2
Selzer, J.3
Munro, S.4
Jeckel, D.5
Aktories, K.6
-
51
-
-
0030611230
-
Bordetella bronchiseptica dermonecrotizing toxin induces reorganization of actin stress fibers through deamidation of Gln-63 of the GTP-binding protein Rho
-
Horiguchi Y., Inoue N., Masuda M., Kashimoto M., Katahira T., Sujimoto N., Matsuda M. Bordetella bronchiseptica dermonecrotizing toxin induces reorganization of actin stress fibers through deamidation of Gln-63 of the GTP-binding protein Rho. Proc. Natl. Acad. Sci. USA. 24:1997;11623-11626.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.24
, pp. 11623-11626
-
-
Horiguchi, Y.1
Inoue, N.2
Masuda, M.3
Kashimoto, M.4
Katahira, T.5
Sujimoto, N.6
Matsuda, M.7
-
52
-
-
0001211598
-
Escherichia coli cytotoxic necrotizing factor 1 increases actin assembly via the p21 Rho GTPase
-
Fiorentini C., Giry M., Donelli G., Falzano L., Aullo P., Boquet P. Escherichia coli cytotoxic necrotizing factor 1 increases actin assembly via the p21 Rho GTPase. Zentrabl. Bakteriol. Suppl. 91:1994;404-405.
-
(1994)
Zentrabl. Bakteriol. Suppl.
, vol.91
, pp. 404-405
-
-
Fiorentini, C.1
Giry, M.2
Donelli, G.3
Falzano, L.4
Aullo, P.5
Boquet, P.6
-
53
-
-
0028231764
-
Cytotoxic necrotizing factor type 2 produced by virulent Escherichia coli modifies the small GTP-binding protein Rho involved in assembly of actin stress fibers
-
Oswald E., Sugai M., Labigne A., Wu H.C., Fiorentini C., Boquet P., O'Brien A.D. Cytotoxic necrotizing factor type 2 produced by virulent Escherichia coli modifies the small GTP-binding protein Rho involved in assembly of actin stress fibers. Proc. Natl. Acad. Sci. USA. 108:1994;3814-3818.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 3814-3818
-
-
Oswald, E.1
Sugai, M.2
Labigne, A.3
Wu, H.C.4
Fiorentini, C.5
Boquet, P.6
O'Brien, A.D.7
-
54
-
-
0029118304
-
Bordetella bronchiseptica dermonecrotizing toxin stimulates assembly of actin stress fibers and focal adhesions by modifying the small GTP-binding protein Rho
-
Horiguchi Y., Senda T., Sugimoto N., Katahira J., Matsuda M. Bordetella bronchiseptica dermonecrotizing toxin stimulates assembly of actin stress fibers and focal adhesions by modifying the small GTP-binding protein Rho. J. Cell Science. 67:1995;3243-3251.
-
(1995)
J. Cell Science
, vol.67
, pp. 3243-3251
-
-
Horiguchi, Y.1
Senda, T.2
Sugimoto, N.3
Katahira, J.4
Matsuda, M.5
-
55
-
-
0032721527
-
Cytotoxic necrotizing factor type 2 produced by pathogenic Escherichia coli deamidates a Gln residue in the conserved G-3 domain of the Rho family and preferentially inhibits the GTPase activity of RhoA and Rac1
-
Sugai M., Hatasaki K., Mogami A., Ohta H., Pérés S., Hérault F., Horiguchi Y., Masuda M., Ueno Y., Komatsusawa H., Sugiaka H., Oswald E. Cytotoxic necrotizing factor type 2 produced by pathogenic Escherichia coli deamidates a Gln residue in the conserved G-3 domain of the Rho family and preferentially inhibits the GTPase activity of RhoA and Rac1. Infect. Immun. 274:1999;6550-6557.
-
(1999)
Infect. Immun.
, vol.274
, pp. 6550-6557
-
-
Sugai, M.1
Hatasaki, K.2
Mogami, A.3
Ohta, H.4
Pérés, S.5
Hérault, F.6
Horiguchi, Y.7
Masuda, M.8
Ueno, Y.9
Komatsusawa, H.10
Sugiaka, H.11
Oswald, E.12
-
56
-
-
0033527746
-
Identification of the C-terminal part of Bordetella dermonecrotic toxin as a transglutaminase for Rho GTPases
-
Schmidt G., Goehring U.M., Schrimer J., Lerm M., Aktories K. Identification of the C-terminal part of Bordetella dermonecrotic toxin as a transglutaminase for Rho GTPases. J. Biol. Chem. 389:1999;31875-31881.
-
(1999)
J. Biol. Chem.
, vol.389
, pp. 31875-31881
-
-
Schmidt, G.1
Goehring, U.M.2
Schrimer, J.3
Lerm, M.4
Aktories, K.5
-
57
-
-
0030716497
-
Structure at 1, 65 A of RhoA and its GTPase-activating protein in complex with a transition state analogue
-
Rittinger K., Walker P.A., Eccleston J.F., Smerdon S.J., Gamblin S.J. Structure at 1, 65 A of RhoA and its GTPase-activating protein in complex with a transition state analogue. Nature. 274:1997;753-762.
-
(1997)
Nature
, vol.274
, pp. 753-762
-
-
Rittinger, K.1
Walker, P.A.2
Eccleston, J.F.3
Smerdon, S.J.4
Gamblin, S.J.5
-
58
-
-
0032867338
-
Identification of the region of Rho involved in substrate recognition by Escherichia coli cytotoxic necrotizing factor 1 (CNF1)
-
Lerm M., Schmidt G., Goehring U.M., Schrimer J., Aktories K., Meyer D.K. Identification of the region of Rho involved in substrate recognition by Escherichia coli cytotoxic necrotizing factor 1 (CNF1). J. Biol. Chem. 267:1999;28999-29004.
-
(1999)
J. Biol. Chem.
, vol.267
, pp. 28999-29004
-
-
Lerm, M.1
Schmidt, G.2
Goehring, U.M.3
Schrimer, J.4
Aktories, K.5
Meyer, D.K.6
-
59
-
-
0034685024
-
Deamidation of RhoA glutamine 63 by the Escherichia coli CNF1 requires a short sequence of the GTPase switch 2 domain
-
Flatau G., Landraud L., Boquet P., Bruzzone Munro P. Deamidation of RhoA glutamine 63 by the Escherichia coli CNF1 requires a short sequence of the GTPase switch 2 domain. Biochem. Biophys. Res. Commun. 274:2000;588-592.
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.274
, pp. 588-592
-
-
Flatau, G.1
Landraud, L.2
Boquet, P.3
Bruzzone Munro, P.4
-
60
-
-
0033600856
-
A coli cytotoxic necrotizing factor 1 (CNF1) reverse cytopathic effects of ADP-ribosylated Rho
-
Barth H., Olenik C., Sehr P., Schmidt G., Aktories K. A coli cytotoxic necrotizing factor 1 (CNF1) reverse cytopathic effects of ADP-ribosylated Rho. J. Biol. Chem. 24:1999;27407-27414.
-
(1999)
J. Biol. Chem.
, vol.24
, pp. 27407-27414
-
-
Barth, H.1
Olenik, C.2
Sehr, P.3
Schmidt, G.4
Aktories, K.5
-
61
-
-
0030742773
-
Molecular localization of the Escherichia coli cytotoxic necrotizing factor 1 cell binding and catalytic domains
-
Lemichez E., Flatau G., Bruzzone M., Boquet P., Gauthier M. Molecular localization of the Escherichia coli cytotoxic necrotizing factor 1 cell binding and catalytic domains. Mol. Microbiol. 273:1997;1061-1070.
-
(1997)
Mol. Microbiol.
, vol.273
, pp. 1061-1070
-
-
Lemichez, E.1
Flatau, G.2
Bruzzone, M.3
Boquet, P.4
Gauthier, M.5
-
62
-
-
0032577588
-
The Rho-deamidating cytotoxic necrotizing factor 1 from Escherichia coli possesses transglutaminase activity
-
Schmidt G., Selzer J., Lerm M., Aktories K. The Rho-deamidating cytotoxic necrotizing factor 1 from Escherichia coli possesses transglutaminase activity. J. Biol. Chem. 67:1998;13669-13674.
-
(1998)
J. Biol. Chem.
, vol.67
, pp. 13669-13674
-
-
Schmidt, G.1
Selzer, J.2
Lerm, M.3
Aktories, K.4
-
63
-
-
0032790756
-
Identification of functional domains of Bordetella dermonecrotizing toxin
-
Kashimoto T., Katahira J., Cornejo W.R., Masuda M., Fukuoh A., Matsuzawa T., Ohnishi T., Horiguchi Y. Identification of functional domains of Bordetella dermonecrotizing toxin. Infect. Immun. 56:1999;3727-3732.
-
(1999)
Infect. Immun.
, vol.56
, pp. 3727-3732
-
-
Kashimoto, T.1
Katahira, J.2
Cornejo, W.R.3
Masuda, M.4
Fukuoh, A.5
Matsuzawa, T.6
Ohnishi, T.7
Horiguchi, Y.8
-
64
-
-
0006014534
-
Clostridium difficile toxin A perturbs cytoskeletal structures and tight junction permeability of cultured human intestinal epithelial cells
-
Hecht G., Pothoulakis C., Lamont J.T., Madara J.L. Clostridium difficile toxin A perturbs cytoskeletal structures and tight junction permeability of cultured human intestinal epithelial cells. J. Clin. Invest. 102:1988;1053-1061.
-
(1988)
J. Clin. Invest.
, vol.102
, pp. 1053-1061
-
-
Hecht, G.1
Pothoulakis, C.2
Lamont, J.T.3
Madara, J.L.4
-
65
-
-
0026577118
-
Clostridium difficile toxin B disrupts the barrier function of T84 monolayers
-
Hecht G., Koutsouris A., Pothoulakis C., Lamont T.J., Madara J.L. Clostridium difficile toxin B disrupts the barrier function of T84 monolayers. Gastroenterology. 92:1992;416-423.
-
(1992)
Gastroenterology
, vol.92
, pp. 416-423
-
-
Hecht, G.1
Koutsouris, A.2
Pothoulakis, C.3
Lamont, T.J.4
Madara, J.L.5
-
66
-
-
0028786658
-
Rho protein regulates tight junction and perijunctional actin organization in polarized epithelia
-
Nusrat A., Giry M., Turner J.R., Colgan S.P., Parkos S.A., Carnes D., Lemichez E., Boquet P., Madara J.L. Rho protein regulates tight junction and perijunctional actin organization in polarized epithelia. Proc. Natl. Acad. Sci. USA. 53:1995;10629-10633.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.53
, pp. 10629-10633
-
-
Nusrat, A.1
Giry, M.2
Turner, J.R.3
Colgan, S.P.4
Parkos, S.A.5
Carnes, D.6
Lemichez, E.7
Boquet, P.8
Madara, J.L.9
-
67
-
-
0024292731
-
Tight junction dynamics: Is the parcellular transport regulated?
-
Madara J.L. Tight junction dynamics: is the parcellular transport regulated? Cell. 17:1988;497-498.
-
(1988)
Cell
, vol.17
, pp. 497-498
-
-
Madara, J.L.1
-
68
-
-
0032476593
-
Completion of FcR-mediated phagocytosis requires the sequential function of Cdc42 and Rac1 and depends on protein phosphatase activity
-
Massol P., Montcourrier P., Guillemot J.C., Chavrier P. Completion of FcR-mediated phagocytosis requires the sequential function of Cdc42 and Rac1 and depends on protein phosphatase activity. EMBO J. 282:1998;6219-6229.
-
(1998)
EMBO J.
, vol.282
, pp. 6219-6229
-
-
Massol, P.1
Montcourrier, P.2
Guillemot, J.C.3
Chavrier, P.4
-
69
-
-
0032573378
-
Identification of two distinct mechanisms of phagocytosis controlled by different Rho GTPases
-
Caron E., Hall A. Identification of two distinct mechanisms of phagocytosis controlled by different Rho GTPases. Science. 9:1998;1717-1721.
-
(1998)
Science
, vol.9
, pp. 1717-1721
-
-
Caron, E.1
Hall, A.2
-
70
-
-
0027363074
-
Induction of phagocytic behaviour in human epithelial cells by Escherichia coli cytotoxic necrotizing factor 1
-
Falzano L., Fiorentini C., Donelli G., Michel E., Kocks C., Cossart P., Cabanié L., Oswald E., Boquet P. Induction of phagocytic behaviour in human epithelial cells by Escherichia coli cytotoxic necrotizing factor 1. Mol. Microbiol. 241:1993;1247-1254.
-
(1993)
Mol. Microbiol.
, vol.241
, pp. 1247-1254
-
-
Falzano, L.1
Fiorentini, C.2
Donelli, G.3
Michel, E.4
Kocks, C.5
Cossart, P.6
Cabanié, L.7
Oswald, E.8
Boquet, P.9
-
71
-
-
0031577747
-
Hindrance of apoptosis and phagocytic behaviour: Induced by Eschericha coli necrotizing factor (CNF1): Two related activities in epithelial cells
-
Fiorentini C., Fabbri A., Matarrese P., Falzano L., Boquet P., Malorni W. Hindrance of apoptosis and phagocytic behaviour: induced by Eschericha coli necrotizing factor (CNF1): two related activities in epithelial cells. Biochem. Biophys. Res. Comm. 15:1997;341-346.
-
(1997)
Biochem. Biophys. Res. Comm.
, vol.15
, pp. 341-346
-
-
Fiorentini, C.1
Fabbri, A.2
Matarrese, P.3
Falzano, L.4
Boquet, P.5
Malorni, W.6
-
72
-
-
0030015626
-
Rho dependent membrane folding causes Shigella entry into epithelial cells
-
Adam T., Giry M., Boquet P., Sansonetti P. Rho dependent membrane folding causes Shigella entry into epithelial cells. EMBO J. 185:1996;3315-3321.
-
(1996)
EMBO J.
, vol.185
, pp. 3315-3321
-
-
Adam, T.1
Giry, M.2
Boquet, P.3
Sansonetti, P.4
-
73
-
-
0031052018
-
Rho, a small GTP-binding protein, is essential for Shigella invasion of epithelial cells
-
Watarai M., Kamata Y., Kosaki S., Sasakawa C. Rho, a small GTP-binding protein, is essential for Shigella invasion of epithelial cells. J. Exp. M. 274:1997;281-292.
-
(1997)
J. Exp. M
, vol.274
, pp. 281-292
-
-
Watarai, M.1
Kamata, Y.2
Kosaki, S.3
Sasakawa, C.4
-
74
-
-
0030448437
-
Requirement for Cdc42 for Salmonella-induced cytoskeletal and nuclear responses
-
Chen L.M., Hobbie S., Galan J.E. Requirement for Cdc42 for Salmonella-induced cytoskeletal and nuclear responses. Science. 112:1996;2115-2118.
-
(1996)
Science
, vol.112
, pp. 2115-2118
-
-
Chen, L.M.1
Hobbie, S.2
Galan, J.E.3
-
75
-
-
0032839369
-
Rho family GTPases control entry of Shigella flexneri into epithelial cells but not intracellular mobility
-
Mounier J., Laurent V., Hall A., Fort P., Carlier M.F., Sansonetti P.J., Egile C. Rho family GTPases control entry of Shigella flexneri into epithelial cells but not intracellular mobility. J. Cell Sci. 18:1999;2069-2080.
-
(1999)
J. Cell Sci.
, vol.18
, pp. 2069-2080
-
-
Mounier, J.1
Laurent, V.2
Hall, A.3
Fort, P.4
Carlier, M.F.5
Sansonetti, P.J.6
Egile, C.7
-
76
-
-
0345593392
-
IpaC induces actin polymerization and filopodia formation during Shigella entry into epithelial cells
-
Tran van Nhieu G., Caron E., Hall A., Sansonetti P.J. IpaC induces actin polymerization and filopodia formation during Shigella entry into epithelial cells. EMBO J. 62:1999;3249-3262.
-
(1999)
EMBO J.
, vol.62
, pp. 3249-3262
-
-
Tran Van Nhieu, G.1
Caron, E.2
Hall, A.3
Sansonetti, P.J.4
-
77
-
-
0031864184
-
Type III secretion systems in bacterial pathogens of animals and plants
-
Hueck C.J. Type III secretion systems in bacterial pathogens of animals and plants. Microbiol. Mol. Biol. Rev. 93:1998;379-433.
-
(1998)
Microbiol. Mol. Biol. Rev.
, vol.93
, pp. 379-433
-
-
Hueck, C.J.1
-
78
-
-
0032577563
-
S. typhimurium encodes an activator of Rho GTPases that induces membrane ruffling and nuclear response in host cells
-
Hardt W.D., Chen L.H., Schuebel K.E., Bustelo X.R., Galan J.E. S. typhimurium encodes an activator of Rho GTPases that induces membrane ruffling and nuclear response in host cells. Cell. 276:1998;815-826.
-
(1998)
Cell
, vol.276
, pp. 815-826
-
-
Hardt, W.D.1
Chen, L.H.2
Schuebel, K.E.3
Bustelo, X.R.4
Galan, J.E.5
-
79
-
-
0030964241
-
Exploitation of the mammalian host cell functions by bacterial pathogens
-
Finlay B., Cossart P. Exploitation of the mammalian host cell functions by bacterial pathogens. Science. 401:1997;718-725.
-
(1997)
Science
, vol.401
, pp. 718-725
-
-
Finlay, B.1
Cossart, P.2
-
80
-
-
0033575956
-
A Salmonella protein antagonizes Rac-1 and Cdc42 to mediate host-cell recovery after bacterial invasion
-
Fu Y., Galàn J.E. A Salmonella protein antagonizes Rac-1 and Cdc42 to mediate host-cell recovery after bacterial invasion. Nature. 274:1999;293-297.
-
(1999)
Nature
, vol.274
, pp. 293-297
-
-
Fu, Y.1
Galàn, J.E.2
-
81
-
-
0033579479
-
The N-terminal domain of Pseudomonas aeruginosa exoenzyme S is a GTPase-activating protein for Rho GTPases
-
Goehring U.M., Schmidt G., Pederson K.J., Aktories K., Barbieri J.T. The N-terminal domain of Pseudomonas aeruginosa exoenzyme S is a GTPase-activating protein for Rho GTPases. J. Biol. Chem. 32:1999;36369-36372.
-
(1999)
J. Biol. Chem.
, vol.32
, pp. 36369-36372
-
-
Goehring, U.M.1
Schmidt, G.2
Pederson, K.J.3
Aktories, K.4
Barbieri, J.T.5
-
82
-
-
0032931551
-
The amino-terminal domain of Pseudomonas aeruginosa ExoS disrupts actin filaments via small-molecular-weight GTP binding proteins
-
Pederson K.J., Vallis A.J., Aktories K., Franck D.W., Barbieri J.T. The amino-terminal domain of Pseudomonas aeruginosa ExoS disrupts actin filaments via small-molecular-weight GTP binding proteins. Mol. Microbiol. 1999;393-401.
-
(1999)
Mol. Microbiol.
, pp. 393-401
-
-
Pederson, K.J.1
Vallis, A.J.2
Aktories, K.3
Franck, D.W.4
Barbieri, J.T.5
|