The role of chromosomal RNAs in marking the X for dosage compensation

Current Opinion in Genetics and Development

Volumn 10, Issue 5, 2000, Pages 555-561

  Kelley, Richard L ^a   Kuroda, Mitzi I ^b  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RNA;

FLY; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETIC ANALYSIS; MAMMAL; NONHUMAN; PRIORITY JOURNAL; REVIEW; RNA ANALYSIS; X CHROMOSOME;

EID: 0033858166     PISSN: 0959437X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-437X(00)00127-1     Document Type: Review

References (55)

1. Vive la difference: Males vs. females in flies vs. worms
2. Dosage compensation in flies and worms: The ups and downs of X-chromosome regulation
3. Guilt by association: Non-coding RNAs, chromosome-specific proteins, and dosage compensation in Drosophila
4. Dosage compensation: Making 1X equal 2X
5. The Drosophila MSL complex acetylates histone H4 at lysine 16, a chromatin modification linked to dosage compensation
6. Activation of transcription through histone H4 acetylation by MOF, an acetyltransferase essential for dosage compensation in Drosophila
7. X-chromosome inactivation in mammals
8. The (epi)genetic control of mammalian X-chromosome inactivation
9. roX1 RNA paints the X chromosome of male Drosophila and is regulated by the dosage compensation system
10. Genes expressed in neurons of adult male Drosophila
11. The roX1 and roX2 RNAs are essential components of the compensasome, which mediates dosage compensation in Drosophila
12. Ordered assembly of roX RNAs into MSL complexes on the dosage compensated X chromosome in Drosophila
13. The product of the mouse Xist gene is a 15 kb inactive X-specific transcript containing no conserved ORF and located in the nucleus
14. The human XlST gene: Analysis of a 17 kb inactive X-specific RNA that contains conserved repeats and is highly localized within the nucleus
15. Conservation of position and exclusive expression of mouse Xist from the inactive X chromosome
16. Characterization of a murine gene expressed from the inactive X chromosome
17. Epigenetic spreading of the Drosophila dosage compensation complex from roX RNA genes into flanking chromatin
18. Regulation of the sex-specific binding of the maleless dosage compensation protein to the male X chromosome in Drosophila
19. Sex-specific regulation of the male-specific lethal-1 dosage compensation gene in Drosophila
20. Drosophila male-specific lethal-2 protein: Structure/function analysis and dependence on MSL-1 for chromosome association
21. Molecular characterization of the male-specific lethal-3 gene and investigation of the regulation of dosage compensation in Drosophila
22. Targeting of MOF, a putative histone acetyl transferase, to the X chromosome of Drosophila melanogaster
23. The NTPase/helicase activities of Drosophila Maleless, an essential factor in dosage compensation
24. Role of the male specific lethal (msl) genes in modifying the effects of sex chromosomal dosage in Drosophila
25. Cloning and dosage compensation of the 6-phosphogluconate dehydrogenase gene (Pgd) of Drosophila melanogaster
26. Dosage compensation of the period gene in Drosophila melanogaster
27. Dosage compensation of the Drosophila white gene requires both the X chromosome environment and multiple intragenic elements
28. A Drosophila insulator protein facilitates dosage compensation of the X chromosome mini-white gene located at autosomal insertion sites
29. Long-range cis effects of ectopic X-inactivation centres on a mouse autosome
30. Xist has properties of the X-chromosome inactivation centre
31. Genetic analysis of the mouse X inactivation center defines an 80-kb multifunction domain
32. X-chromosome inactivation: A repeat hypothesis
33. Requirement for Xist in X chromosome inactivation
34. Xist-deficient mice are defective in dosage compensation but not spermatogenesis
35. A 450 kb transgene displays properties of the mammalian X-inactivation center
36. Xist yeast artificial chromosome transgenes function as X-inactivation centers only in multicopy arrays and not as single copies
37. A shift from reversible to irreversible X inactivation is triggered during ES cell differentiation
38. The human X-inactivation centre is not required for maintenance of X-chromosome inactivation
39. Conditional deletion of Xist disrupts histone macroH2A localization but not maintenance of X inactivation
40. Promoter-specific hypoacetylation of X inactivated genes
41. Histone macroH2A1 is concentrated in the inactive X chromosome in female mammals
42. Histone macroH2A1.2 relocates to the inactive X chromosome after initiation and propagation of X-inactivation
43. Human X inactivation center induces random X chromosome inactivation in male transgenic mice
44. Human XlST yeast artificial chromosome transgenes show partial X inactivation center function in mouse embryonic stem cells
45. X chromosome inactivation is mediated by Xist RNA stabilization
46. Stabilization of Xist RNA mediates initiation of X chromosome inactivation
47. Developmentally regulated Xist promoter switch mediates initiation of X inactivation
48. Tsix, a gene antisense to Xist at the X-inactivation centre
49. Molecular cloning of antisense transcripts of the mouse Xist gene
50. 0 promoter
51. Targeted mutagenesis of Tsix leads to nonrandom X inactivation
52. Role of the region 3' to Xist exon 6 in the counting process of X-chromosome inactivation
53. A new structure for the murine Xist gene and its relationship to chromosome choice/counting during X-chromosome inactivation
54. Chromosomal basis of X chromosome inactivation: Identification of a multigene domain in Xp1 1.21-p11.22 that escapes X inactivation