Tryptase inhibitors in the treatment of pulmonary diseases

Current Opinion in Investigational Drugs

Volumn 1, Issue 1, 2000, Pages 79-85

  Gangloff, A R ^a  

^a Axys Pharmaceuticals Inc   (United States)

Author keywords

Asthma; Inflammation; Inflammatory disease; Mast cell; Tryptase; Tryptase inhibitor

Indexed keywords

1,5 BIS [4 [(3 CARBAMIMIDOYL BENZENESULFONYLAMINO)METHYL]PHENOXY] PENTANE; 1,5 BIS[4 (5 AMIDINOBENZOFURAN 2 YLCARBONYL)PIPERAZINYLCARBONYLMETHOXY]CYCLOOCTANE; APC 2059; APROTININ; BAY 35 8535; BAY 44 3428; BENZIMIDAZOLE DERIVATIVE; BENZOFURAN DERIVATIVE; BENZOIC ACID ESTER DERIVATIVE; BETA LACTAM DERIVATIVE; CHELATING AGENT; ISOTHIAZOLE DERIVATIVE; MOL 2668; MYELOPEROXIDASE; N (1 HYDROXY 2 NAPHTHOYL)ARGINYLPROLINAMIDE; PYRROLE DERIVATIVE; SERINE PROTEINASE INHIBITOR; TRYPTASE; UNCLASSIFIED DRUG;

BRONCHOSPASM; CLINICAL TRIAL; DOSE RESPONSE; DRUG ACTIVITY; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG HALF LIFE; DRUG SAFETY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; EXPERIMENTAL MODEL; HUMAN; INFLAMMATION; LUNG DISEASE; MAST CELL DEGRANULATION; NONHUMAN; REVIEW; STRUCTURE ANALYSIS;

ANIMALS; CHELATING AGENTS; HUMANS; LUNG DISEASES; SERINE ENDOPEPTIDASES; SERINE PROTEINASE INHIBITORS; TRYPTASES;

EID: 0033760732     PISSN: 09678298     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

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