The role of Glu192 in the allosteric control of the S2' and S3' subsites of thrombin

Journal of Biological Chemistry

Volumn 275, Issue 2, 2000, Pages 809-816

  Marque, Pierre Emmanuel ^a   Spuntarelli, Roberta ^a   Juliano, Luiz ^b   Aiach, Martine ^a   Le Bonniec, Bernard F ^a  

^a INSERM   (France)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTAMIC ACID; HEPARIN; THROMBIN; TRYPSIN; FLUORESCENT DYE; HIRUDIN DERIVATIVE; PEPTIDE FRAGMENT; RECOMBINANT PROTEIN;

ALLOSTERISM; ARTICLE; BINDING SITE; ENZYME STRUCTURE; ENZYME SUBSTRATE; ENZYME SUBUNIT; HYDROLYSIS; PRIORITY JOURNAL; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; CHEMISTRY; COMPARATIVE STUDY; ENZYME ACTIVE SITE; KINETICS; METABOLISM; MOLECULAR GENETICS; POINT MUTATION; SITE DIRECTED MUTAGENESIS;

ALLOSTERIC REGULATION; ALLOSTERIC SITE; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; CATALYTIC DOMAIN; FLUORESCENT DYES; GLUTAMIC ACID; HEPARIN; HIRUDINS; HYDROLYSIS; KINETICS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PEPTIDE FRAGMENTS; POINT MUTATION; RECOMBINANT PROTEINS; THROMBIN; TRYPSIN;

EID: 0033621805     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.275.2.809     Document Type: Article

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