Ligand binding to thrombin exosite II induces dissociation of the thrombin-heparin cofactor II(L444R) complex

Biochemistry

Volumn 37, Issue 9, 1998, Pages 3203-3209

  Han, Jin Hua ^a   Tollefsen, Douglas M ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DERMATAN SULFATE; HEPARIN; HEPARIN COFACTOR II; IMMUNOGLOBULIN G; LIGAND; MUTANT PROTEIN; PROLINE; SERINE PROTEINASE INHIBITOR; THROMBIN; TRYPTOPHAN;

ALLOSTERISM; ARTICLE; BINDING AFFINITY; CONFORMATIONAL TRANSITION; ENZYME ACTIVE SITE; HUMAN; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; PROTEIN STABILITY; SWINE;

ARGININE; BINDING SITES; HEPARIN COFACTOR II; HUMANS; LIGANDS; MACROMOLECULAR SUBSTANCES; MODELS, CHEMICAL; PROLINE; PROTEIN BINDING; PROTEIN CONFORMATION; STRUCTURE-ACTIVITY RELATIONSHIP; THROMBIN; TRYPTOPHAN;

EID: 0032478169     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9722195     Document Type: Article

References (44)

1. Gettins, P. G. W., Patston, P. A., and Olson, S. T. (1996) Serpins: Structure, function and biology, R. G. Landes Co., Austin, TX.
2. Parker, K. A., and Tollefsen, D. M. (1985) J. Biol. Chem. 260, 3501-3505.
3. Church, F. C., Noyes, C. M., and Griffith, M. J. (1985) Proc. Natl. Acad. Sci. U.S.A. 82, 6431-6434.
4. Tollefsen, D. M., Pestka, C. A., and Monafo, W. J. (1983) J. Biol. Chem. 258, 6713-6716.
5. Tollefsen, D. M. (1995) Thromb. Haemostasis 74, 1209-1214.
6. Derechin, V. M., Blinder, M. A., and Tollefsen, D. M. (1990) J. Biol. Chem. 265, 5623-5628.
7. Griffith, M. J., Noyes, C. M., Tyndall, J. A., and Church, F. C. (1985) Biochemistry 24, 6777-6782.
8. Han, J.-H., Van Deerlin, V. M. D., and Tollefsen, D. M. (1997) J. Biol. Chem. 272, 8243-8249.
9. Ciaccia, A. V., Willemze, A. J., and Church, F. C. (1997) J. Biol. Chem. 272, 888-893.
10. Church, F. C., Pratt, C. W., Noyes, C. M., Kalayanamit, T., Sherrill, G. B., Tobin, R. B., and Meade, J. B. (1989) J. Biol. Chem. 264, 18419-18425.
11. Sheehan, J. P., and Sadler, J. E. (1994) Proc. Natl. Acad. Sci. U.S.A. 91, 5518-5522.
12. Gan, Z.-R., Li, Y., Chen, Z., Lewis, S. D., and Shafer, J. A. (1994) J. Biol. Chem. 269, 1301-1305.
13. Ye, J., Rezaie, A. R., and Esmon, C. T. (1994) J. Biol. Chem. 269, 17965-17970.
14. Tsiang, M., Jain, A. K., Dunn, K. E., Rojas, M. E., Leung, L. L., and Gibbs, C. S. (1995) J. Biol. Chem. 270, 16854-16863.
15. Blinder, M. A., and Tollefsen, D. M. (1990) J. Biol. Chem. 265, 286-291.
16. Ragg, H., Ulshöfer, T., and Gerewitz, J. (1990) J. Biol. Chem. 265, 5211-5218.
17. Whinna, H. C., Blinder, M. A., Szewczyk, M., Tollefsen, D. M., and Church, F. C. (1991) J. Biol. Chem. 266, 8129-8135.
18. Bode, W., Mayr, I., Baumann, U., Huber, R., Stone, S. R., and Hofsteenge, J. (1989) EMBO J. 8, 3467-3475.
19. Le Bonniec, B. F., Guinto, E. R., MacGillivray, R. T. A., Stone, S. R., and Esmon, C. T. (1993) J. Biol. Chem. 268, 19055-19061.
20. Colwell, N. S., Tollefsen, D. M., and Blinder, M. A. (1997) Br. J. Haematol. 97, 219-226.
21. Maimone, M. M., and Tollefsen, D. M. (1988) Biochem. Biophys. Res. Commun. 152, 1056-1061.
22. Bitter, T., and Muir, H. (1962) Anal. Biochem. 4, 340-344.
23. Sanger, F., Nicklen, S., and Coulson, A. R. (1977) Proc. Natl. Acad. Sci. U.S.A. 74, 5463-5467.
24. Tollefsen, D. M., Majerus, D. W., and Blank, M. K. (1982) J. Biol. Chem. 257, 2162-2169.
25. Matheson, N. R., van Halbeek, H., and Travis, J. (1991) J. Biol. Chem. 266, 13489-13491.
26. Lawrence, D. A., Ginsburg, D., Day, D. E., Berkenpas, M. B., Verhamme, I. M., Kvassman, J.-O., and Shore, J. D. (1995) J. Biol. Chem. 270, 25309-25312.
27. Jesty, J. (1979) J. Biol. Chem. 254, 10044-10050.
28. Danielsson, Å., and Björk, I. (1983) Biochem. J. 213, 345-353.
29. Cooperman, B. S., Stavridi, E., Nickbarg, E., Rescorla, E., Schechter, N. M., and Rubin, H. (1993) J. Biol. Chem. 268, 23616-23625.
30. Danielsson, Å., Raub, E., Lindahl, U., and Björk, I. (1986) J. Biol. Chem. 261, 15467-15473.
31. Olson, S. T., Halvorson, H. R., and Björk, I. (1991) J. Biol. Chem. 266, 6342-6352.
32. Sheehan, J. P., Tollefsen, D. M., and Sadler, J. E. (1994) J. Biol. Chem. 269, 32747-32751.
33. Wells, C. M., and DiCera, E. (1992) Biochemistry 31, 11721-11730.
34. Di Cera, E., Guinto, E. R., Vindigni, A., Dang, Q. D., Ayala, Y. M., Wuyi, M., and Tulinsky, A. (1995) J. Biol. Chem. 270, 22089-22092.
35. Ye, J., Esmon, N. L., Esmon, C. T., and Johnson, A. E. (1991) J. Biol. Chem. 266, 23016-23021.
36. Parry, M. A. A., Stone, S. R., Hofsteenge, J., and Jackman, P. (1993) Biochem. J. 290, 665-670.
37. De Christofaro, R., De Candia, E., Picozzi, M., and Landolfi, R. (1995) J. Mol. Biol. 245, 447-458.
38. Arni, R. K., Padmanabhan, K., Padmanabhan, K. P., Wu, T.-P., and Tulinsky, A. (1993) Biochemistry 32, 4727-4737.
39. Bock, P. E. (1992) J. Biol. Chem. 267, 14974-14981.
40. Le Bonniec, B. F., Guinto, E. R., and Esmon, C. T. (1992) J. Biol. Chem. 267, 19341-19348.
41. Le Bonniec, B. F., Guinto, E. R., and Stone, S. R. (1995) Biochemistry 34, 12241-12248.
42. Rezaie, A. R. (1996) Biochemistry 35, 1918-1924.
43. Malkowski, M. G., Martin, P. D., Guzik, J. C., and Edwards, B. F. P. (1997) Protein Sci. 6, 1438-1448.
44. van de Locht, A., Bode, W., Huber, R., Le Bonniec, B. F., Stone, S. R., Esmon, C. T., and Stubbs, M. T. (1997) EMBO J. 16, 2977-2984.