Bovine thrombin complexed with an uncleavable analog of residues 7-19 of fibrinogen Aα: Geometry of the catalytic triad and interactions of the P1', P2', and P3' substrate residues

Biochemistry

Volumn 35, Issue 40, 1996, Pages 13030-13039

  Martin, Philip D ^a   Malkowski, Michael G ^a   DiMaio, John ^b   Konishi, Yasuo ^b   Ni, Feng ^b   Edwards, Brian F P ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL RESEARCH COUNCIL CANADA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

FIBRINOGEN; THROMBIN;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CATTLE; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME SUBSTRATE COMPLEX; MICHAELIS CONSTANT; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; SEQUENCE ANALYSIS;

ANIMALS; BINDING SITES; CATTLE; CRYSTALLOGRAPHY, X-RAY; FIBRINOGEN; HIRUDINS; HYDROGEN BONDING; MODELS, MOLECULAR; PEPTIDE FRAGMENTS; PROTEIN CONFORMATION; THROMBIN;

BOS TAURUS; BOVINAE;

EID: 0029819059     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi960656y     Document Type: Article

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