Nutrient-induced insulin resistance

Molecular and Cellular Endocrinology

Volumn 151, Issue 1-2, 1999, Pages 143-149

  Proietto, Joseph ^a   Filippis, Anthony ^a   Nakhla, Christine ^a   Clark, Stella ^b  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

Author keywords

FFA; Gluconeogenesis; Glucose toxicity; Glucose transport; Hexosamine biosynthesis; Insulin action; PKC; TNF

Indexed keywords

2 [1 (3 AMIDINOTHIOPROPYL) 1H INDOL 3 YL] 3 (1 METHYL 1H INDOL 3 YL)MALEIMIDE; FATTY ACID; GLUCOSE; HEXOSAMINE; INSULIN; STREPTOZOCIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; GENETIC ASSOCIATION; GENETIC RISK; GLUCONEOGENESIS; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; HORMONE ACTION; INSULIN METABOLISM; INSULIN RESISTANCE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; RAT; REVIEW;

DIET; DIETARY FATS; GLUCOSE; HUMANS; INSULIN RESISTANCE;

EID: 0033602936     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0303-7207(99)00050-7     Document Type: Review

References (68)

1. Allard W.J., Gibbs E.M., Witters L.A., Lienhard G.E. The glucose transporter in human fibroblasts is phosphorylated in response to phorbol ester but not in response to growth factors. Biochim. Biophys. Acta. 929:1987;288-295.
2. American Diabetes Association, 1998. Economic consequences of diabetes mellitus in the US in 1997. Diabetes Care 21, 296-309.
3. Amos A.F., McCarty D.J., Zimmet P. The rising global burden of diabetes and its complications: estimates and projections to the year 2010. Diabet. Med. 14((Suppl. 5)):1997;S1-S85.
4. Andrikopoulos S., Proietto J. The biochemical basis of increased hepatic glucose production in a mouse model of type 2 (non-insulin-dependent) diabetes mellitus. Diabetologia. 38:1995;1389-1396.
5. Baron A.D., Brechtel G., Edelman S.V. Effects of free fatty acids and ketone bodies on in vivo non-insulin mediated glucose utilization and production in man. Metabolism. 38:1989;1056-1061.
6. Baron A.D., Zhu J.S., Zhu J.H., Weldon H., Maianu L., Garvey W.T. Glucosamine induces insulin resistance in vivo by affecting GLUT 4 translocation in skeletal muscle. Implications for glucose toxicity. J. Clin. Invest. 96:1995;2792-2801.
7. Baur L.A., O'Connor J., Pan D.A., Kriketos A.D., Storlien L.H. The fatty acid composition of skeletal muscle membrane phospholipid: its relationship with the type of feeding and plasma glucose levels in young children. Metabolism. 47:1998;106-112.
8. Bevilacqua S., Bonadonna R., Buzzigoli G., Boni C., Ciociaro D., Maccari F., Giorico M.A., Ferrannini E. Acute elevation of free fatty acid levels leads to hepatic insulin resistance in obese individuals. Metabolism. 36:1987;502-506.
9. Boden G., Chen X., Ruiz J., White J.V., Rossetti L. Mechanism of fatty acid-induced inhibition of glucose uptake. J. Clin. Invest. 93:1994;2438-2446.
10. Bollag G.E., Roth R.A., Beaudoin J., Mochly-Rosen D., Koshland D.E. Jr Protein kinase C directly phosphorylates the insulin receptor in vitro and reduces its protein-tyrosine kinase activity. Proc. Natl. Acad. Sci. USA. 83:1986;5822-5824.
11. Borkman M., Storlien L.H., Pan D.A., Jenkins A.B., Chisholm D.J., Campbell L.V. The relation between insulin sensitivity and the fatty-acid composition of skeletal-muscle phospholipids. New. Engl. J. Med. 328:1993;238-244.
12. Chen H., Ing B.L., Robinson K.A., Feagin A.C., Buse M.G., Quon M.J. Effects of overexpression of glutamine:fructose-6-phosphate amidotransferase (GFAT) and glucosamine treatment on translocation of GLUT4 in rat adipose cells. Mol. Cell. Endocrinol. 135:1997;67-77.
13. Consoli A., Nurjhan N., Capani F., Gerich J. Predominant role of gluconeogenesis in increased hepatic glucose production in NIDDM. Diabetes. 38:1989;550-557.
14. Craven P.A., DeRubertis F.R. Protein kinase C is activated in glomeruli from streptozotocin diabetic rats. Possible mediation by glucose. J. Clin. Invest. 83:1989;1667-1675.
15. Dunlop M.E., Larkins R.G. Pancreatic islets synthesize phospholipids de novo from glucose via acyl-dihydroxyacetone phosphate. Biochem. Biophys. Res. Commun. 132:1985;467-473.
16. Feinstein R., Kanety H., Papa M.Z., Lunenfeld B., Karasik A. Tumor necrosis factor-alpha suppresses insulin-induced tyrosine phosphorylation of insulin receptor and its substrates. J. Biol. Chem. 268:1993;26055-26058.
17. Ferrannini E., Barrett E.J., Bevilacqua S., DeFronzo R.A. Effect of fatty acids on glucose production and utilization in man. J. Clin. Invest. 72:1983;1737-1747.
18. Filippis A., Clark S., Proietto J. Increased flux through the hexosamine biosynthesis pathway inhibits glucose transport acutely by activation of PKC. Biochem. J. 324:1997;981-985.
19. Filippis A., Clark S., Proietto J. A role for gp160 in constitutive but not insulin-stimulated GLUT4 trafficking: dissociation of gp160 and GLUT4 localization. Biochem. J. 330:1998;405-411.
20. Fisher M.D., Frost S.C. Translocation of GLUT1 does not account for elevated glucose transport in glucose-deprived 3T3-L1 adipocytes. J. Biol. Chem. 271:1996;11806-11809.
21. Garvey W.T., Olefsky J.M., Matthaei S., Marshall S. Glucose and insulin co-regulate the glucose transport system in primary cultured adipocytes. A new mechanism of insulin resistance. J. Biol. Chem. 262:1987;189-197.
22. Hartz A.J., Rupley D.C. Jr, Kalkhoff R.D., Rimm A.A. Relationship of obesity to diabetes: influence of obesity level and body fat distribution. Prev. Med. 12:1983;351-357.
23. Hawkins M., Barzilai N., Liu R., Hu M., Chen W., Rossetti L. Role of the glucosamine pathway in fat-induced insulin resistance. J. Clin. Invest. 99:1997;2173-2182.
24. Hotamisligil G.S., Shargill N.S., Spiegelman B.M. Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science. 259:1993;87-91.
25. Hotamisligil G.S., Budavari A., Murray D., Spiegelman B.M. Reduced tyrosine kinase activity of the insulin receptor in obesity-diabetes. Central role of tumor necrosis factor-alpha. J. Clin. Invest. 94:1994a;1543-1549.
26. Hotamisligil G.S., Murray D.L., Choy L.N., Spiegelman B.M. Tumor necrosis factor alpha inhibits signaling from the insulin receptor. Proc. Natl. Acad. Sci. USA. 24(91):1994b;4854-4858.
27. Hotamisligil G.S., Arner P., Caro J.F., Atkinson R.L., Spiegelman B.M. Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance. J. Clin. Invest. 95:1995;2409-2415.
28. Hotamisligil G.S., Peraldi P., Budavari A., Ellis R., White M.F., Spiegelman B.M. IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance. Science. 271:1996;665-668.
29. Jenkins A.B., Storlien L.H., Chisholm D.J., Kraegen E.W. Effects of nonesterified fatty acid availability on tissue-specific glucose utilization in rats in vivo. J. Clin. Invest. 82:1988;293-299.
30. Kandror K., Pilch P.F. Identification and isolation of glycoproteins that translocate to the cell surface from GLUT4-enriched vesicles in an insulin-dependent fashion. J. Biol. Chem. 269:1994a;138-142.
31. Kandror K.V., Pilch P.F. gp160, a tissue-specific marker for insulin-activated glucose transport. Proc. Natl. Acad. Sci. USA. 91:1994b;8017-8021.
32. Kanety H., Feinstein R., Papa M.Z., Hemi R., Karasik A. Tumor necrosis factor alpha-induced phosphorylation of insulin receptor substrate-1 (IRS-1). Possible mechanism for suppression of insulin-stimulated tyrosine phosphorylation of IRS-1. J. Biol. Chem. 270:1995;23780-23784.
33. Katsuki A., Sumida Y., Murashima S., Murata K., Takarada Y., Ito K., Fujii M., Tsuchihashi K., Goto H., Nakatani K., Yano Y. Serum levels of tumor necrosis factor-alpha are increased in obese patients with noninsulin-dependent diabetes mellitus. J. Clin. Endocrinol. Metab. 83:1998;859-862.
34. Kim J.K., Wi J.K., Youn J.H. Plasma free fatty acids decrease insulin-stimulated skeletal muscle glucose uptake by suppressing glycolysis in conscious rats. Diabetes. 45:1996;446-453.
35. Kissebah A.H., Vydelingum N., Murray R., Evans D.J., Hartz A.J., Kalkhoff R.K., Adams P.W. Relation of body fat distribution to metabolic complications of obesity. J. Clin. Endocrinol. Metab. 54:1982;254-258.
36. Kornfeld S., Kornfeld R., Neubeld E.F., O'Brien P.J. The feedback control of sugar nucleotide biosynthesis in the liver. Proc. Natl. Acad. Sci. USA. 52:1964;371-379.
37. Kraegen E.W., Clark P.W., Jenkins A.B., Daley E.A., Chisholm D.J., Storlien L.H. Development of muscle insulin resistance after liver insulin resistance in high-fat-fed rats. Diabetes. 40:1991;1397-1403.
38. Kruszynska Y.T., McCormack J.G., McIntyre N. Effects of non-esterified fatty acid availability on insulin stimulated glucose utilization and tissue pyruvate dehydrogenase activity in the rat. Diabetologia. 33:1990;396-402.
39. Lang C.H., Dobrescu C., Bagby G.J. Tumor necrosis factor impairs insulin action on peripheral glucose disposal and hepatic glucose output. Endocrinology. 130:1992;43-52.
40. Lee K.U., Lee H.K., Koh C.S., Min H.K. Artificial induction of intravascular lipolysis by lipid-heparin infusion leads to insulin resistance in man. Diabetologia. 31:1988;285-290.
41. Magnan C., Gilbert M., Kahn B.B. Chronic free fatty acid infusion in rats results in insulin resistance but no alteration in insulin responsive glucose transporter levels in skeletal muscle. Lipids. 31:1996;1141-1149.
42. Marshall S., Bacote V., Traxinger R.R. Discovery of a metabolic pathway mediating glucose-induced desensitization of the glucose transport system. Role of hexosamine biosynthesis in the induction of insulin resistance. J. Biol. Chem. 266:1991a;4706-4712.
43. Marshall S., Bacote V., Traxinger R.R. Complete inhibition of glucose-induced desensitization of the glucose transport system by inhibitors of mRNA synthesis. Evidence for rapid turnover of glutamine:fructose-6-phosphate amidotransferase. J. Biol. Chem. 266:1991b;10155-10161.
44. McKnight G.L., Mudri S.L., Mathewes S.L., Traxinger R.R., Marshall S., Sheppard P.O., O'Hara P.J. Molecular cloning, cDNA sequence, and bacterial expression of human glutamine:fructose-6-phosphate amidotransferase. J. Biol. Chem. 267:1992;25208-25212.
45. McClain D.A., Paterson A.J., Roos M.D., Wei X., Kudlow J.E. Glucose and glucosamine regulate growth factor gene expression in vascular smooth muscle cells. Proc. Natl. Acad. Sci. USA. 89:1992;8150-8154.
46. Muller H.K., Kellerer M., Ermel B., Muhlhofer A., Obermaier-Kusser B., Vogt B., Haring H.U. Prevention by protein kinase C inhibitors of glucose-induced insulin-receptor tyrosine kinase resistance in rat fat cells. Diabetes. 40:1991;1440-1448.
47. Napoli R., Hirshman M.F., Horton E.S. Mechanisms and time course of impaired skeletal muscle glucose transport activity in streptozocin diabetic rats. J. Clin. Invest. 96:1995;427-437.
48. Nurjhan N., Consoli A., Gerich J. Increased lipolysis and its consequences on gluconeogenesis in non-insulin-dependent diabetes mellitus. J. Clin. Invest. 89:1992;169-175.
49. Oakes N.D., Cooney G.J., Camilleri S., Chisholm D.J., Kraegen E.W. Mechanisms of liver and muscle insulin resistance induced by chronic high-fat feeding. Diabetes. 46:1997;1768-1774.
50. Pan D.A., Lillioja S., Milner M.R., Kriketos A.D., Baur L.A., Bogardus C., Storlien L.H. Skeletal muscle membrane lipid composition is related to adiposity and insulin action. J. Clin. Invest. 96:1995;2802-2808.
51. Pan D.A., Lillioja S., Kriketos A.D., Milner M.R., Baur L.A., Bogardus C., Jenkins A.B., Storlien L.H. Skeletal muscle triglyceride levels are inversely related to insulin action. Diabetes. 46:1997;983-988.
52. Peraldi P., Hotamisligil G.S., Buurman W.A., White M.F., Spiegelman B.M. Tumor necrosis factor (TNF)-alpha inhibits insulin signaling through stimulation of the p55 TNF receptor and activation of sphingomyelinase. J. Biol. Chem. 271:1996;13018-13022.
53. Puhakainen I., Koivisto V.A., Yki-Jarvinen H. Lipolysis and gluconeogenesis from glycerol are increased in patients with noninsulin-dependent diabetes mellitus. J. Clin. Endocrinol. Metab. 75:1992;789-794.
54. Randle, P.J., Garland, P.B., Hales, C.N., Newsholme, E.A., 1963. The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus. Lancet I, 785-789.
55. Robinson K.A., Sens D.A., Buse M.G. Pre-exposure to glucosamine induces insulin resistance of glucose transport and glycogen synthesis in isolated rat skeletal muscles. Study of mechanisms in muscle and in rat-1 fibroblasts overexpressing the humaninsulin receptor. Diabetes. 42:1993;1333-1346.
56. Rosella G., Zajac J.D., Baker L., Kaczmarcyk S.J., Andrikopoulos S., Adams T.E., Proietto J. Impaired glucose tolerance and increased weight gain in transgenic rats overexpressing a non-insulin-responsive phosphoenolpyruvate carboxykinase gene. Mol. Endocrinol. 9:1995;1396-1404.
57. Rossetti L., Smith D., Shulman G.I., Papachristou D., DeFronzo R.A. Correction of hyperglycemia with phlorizin normalizes tissue sensitivity to insulin in diabetic rats. J. Clin. Invest. 79:1987;1510-1515.
58. Rossetti L., Hawkins M., Chen W., Gindi J., Barzilai N. In vivo glucosamine infusion induces insulin resistance in normoglycemic but not in hyperglycemic conscious rats. J. Clin. Invest. 96:1995;132-140.
59. Schreyer S.A., Chua S.C. Jr, LeBoeuf R.C. Obesity and diabetes in TNF-alpha receptor-deficient mice. J. Clin. Invest. 102:1998;402-411.
60. Storlien L.H., James D.E., Burleigh K.M., Chisholm D.J., Kraegen E.W. Fat feeding causes widespread in vivo insulin resistance, decreased energy expenditure, and obesity in rats. Am. J. Physiol. 251:1986;E576-E583.
61. Storlien L.H., Kraegen E.W., Chisholm D.J., Ford G.L., Bruce D.G., Pascoe W.S. Fish oil prevents insulin resistance induced by high-fat feeding in rats. Science. 237:1987;885-888.
62. Storlien L.H., Jenkins A.b., Chisholm D.J., Pacoe W.S., Khouri S., Kraegen E.W. Influence of dietary fat composition on development of insulin resistance in rats. Relationship to muscle triglyceride and -3 fatty acids in muscle phospholipid. Diabetes. 40:1991;280-289.
63. Thorburn A.W., Baldwin M.E., Rosella G., Zajac D., Fabris S., Song S., Proietto J. Features of syndrome X develop in transgenic rats expressing a non-insulin responsive phosphoenolpyruvate carboxykinase gene. Diabetologia. 42:1999;419-426.
64. Unger R.H., Grundy S. Hyperglycaemia as an inducer as well as a consequence of impaired islet cell function and insulin resistance: implications for the management of diabetes. Diabetologia. 28:1985;119-121.
65. Uysal K.T., Wiesbrock S.M., Marino M.W., Hotamisligil G.S. Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function. Nature. 389:1997;610-614.
66. Ventre J., Doebber T., Wu M., MacNaul K., Stevens K., Pasparakis M., Kollias G., Moller D.E. Targeted disruption of the tumor necrosis factor-alpha gene: metabolic consequences in obese and non-obese mice. Diabetes. 46:1997;1526-1531.
67. Virkamaki A., Daniels M.C., Hamalainen S., Utriainen T., McClain D., Yki-Jarvinen H. Activation of the hexosamine pathway by glucosamine in vivo induces insulin resistance in multiple insulin sensitive tissues. Endocrinology. 138:1997;2501-2507.
68. Walker M., Fulcher G.R., Catalano C., Petranyi G., Orskov H., Alberti K.G.M.M. Physiological levels of plasma non-esterified fatty acids impair forearm glucose uptake in normal man. Clinical. science. 79:1990;167-174.