Increased flux through the hexosamine biosynthesis pathway inhibits glucose transport acutely by activation of protein kinase C

Biochemical Journal

Volumn 324, Issue 3, 1997, Pages 981-985

  Filippis, Anthony ^a   Clark, Stella ^b   Proietto, Joseph ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

2 [1 (3 AMIDINOTHIOPROPYL) 1H INDOL 3 YL] 3 (1 METHYL 1H INDOL 3 YL)MALEIMIDE; AZASERINE; ENZYME INHIBITOR; GLUCOSAMINE; GLUCOSE; GLUCOSE TRANSPORTER; GLUTAMINE FRUCTOSE 6 PHOSPHATE AMINOTRANSFERASE; HEXOSAMINE; INSULIN; MEMBRANE ENZYME; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR;

ADIPOCYTE; ANIMAL CELL; ARTICLE; CARBOHYDRATE SYNTHESIS; CONTROLLED STUDY; ENZYME ACTIVATION; GLUCOSE TRANSPORT; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALIA;

EID: 0030787345     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/bj3240981     Document Type: Article

References (32)

1. Garvey, W. T., Olefsky, J. M., Matthaei, S. and Marshall, S. (1987) J. Biol. Chem. 262, 189-197
2. Rossetti, L., Smith, D., Shulman, G. I., Papachristou, D. and DeFronzo, R. A. (1987) J. Clin. Invest. 79, 1510-1515
3. Marshall, S., Bacole, V. and Traxinger, R. R. (1991) J. Biol. Chem. 266, 4706-4712
4. Robinson, K. A., Sens, D. A. and Buse, M. G. (1993) Diabetes 42, 1333-1346
5. Robinson, K. A., Weinstein, M. L., Lindenmayer, G. E. and Buse, M. G. (1995) Diabetes 44, 1438-1446
6. Traxinger, R. R. and Marshall, S. (1989) J. Biol. Chem. 264, 20910-20916
7. Bollag, G. E., Roth, R. A., Beaudoin, J., Mochly-Rosen, D. and Koshland, D. E. J. (1986) Proc. Natl. Acad. Sci. U.S.A. 83, 5822-5824
8. Lee, T. S., MacGregor, L. C., Fluharty, S. and King, G. L. (1989) J. Clin. Invest. 83, 90-94
9. Craven, P. A. and DeRubertis, F. R. (1989) J. Clin. Invest. 83, 1667-1675
10. Muller, H. K., Kellerer, M., Ermel, B., Muhlhofer, A., Obermaler-Kusser, B., Vogt, B. and Haring, H. U. (1991) Diabetes 40, 1440-1448
11. Dunlop, M. E. and Larkins, R. G. (1985) Biochem. Biophys. Res. Commun. 132, 467-473
12. Takayama, S., White, M. and Kahn, C. R. (1988) J. Biol. Chem. 263, 3440-3447
13. Chin, J. E., Liu, F. and Roth, R. A. (1994) Mol. Endocrinol. 8, 51-58
14. Rodbell, M. (1964) J. Biol. Chem. 239, 375-380
15. Kelada, A. S. M., Macaulay, S. L. and Proietto, J. (1992) J. Biol. Chem. 267, 7021-7025
16. Olefsky, J. M. (1978) Biochem. J. 172, 137-145
17. Haring, H. U., Biermann, E. and Kemmler, W. (1981) Am. J. Physiol. 240, E556-E565
18. Traxinger, R. R. and Marshall, S. (1990) Biochem. Int. 22, 607-615
19. Thomas, T. P., Gopalakrishna, R. and Anderson, W. B. (1987) Methods Enzymol. 141, 399-411
20. Dunlop, M. E. and Larkins, R. G. (1935) Biochem. Biophys. Res. Commun. 132, 467-473
21. Laemmli, U. K. (1970) Nature (London) 227, 680-685
22. Towbin, H., Staehelin, T. and Gordon, J. (1979) Proc. Natl. Acad. Sci. U.S.A. 76, 4350-4354
23. Burnette, W. N. (1981) Anal. Biochem. 112, 195-203
24. Bradford, M. M. (1976) Anal. Biochem. 72, 248-254
25. Draznin, B., Leitner, J. W., Sussman, K. E. and Sherman, N. A. (1988) Biochem. Biophys. Res. Commun. 156, 570-575
26. Farese, R. V., Standaert, M. L., Arnold, T. P., Yamada, K., Musunuru, K., Hernandez, H., Mischack, H. and Cooper, D. R. (1994) J. Clin. Invest. 93, 1894-1899
27. Allard, W. J., Gibbs, E. M., Witters. L. A. and Lienhard, G. E. (1987) Biochim. Biophys. Acta 929, 288-295
28. Fisher, M. D. and Frost, S. C. (1996) J. Biol. Chem. 271, 11806-11809
29. Napoli, R., Hirshman. M. F. and Horton, E. S. (1995) J. Clin. Invest. 96, 427-437
30. Baron, A. D., Zhu, J. S., Weldon, H., Mainanu, L. and Garvey, W. T. (1995) J. Clin. Invest. 96, 2792-2801
31. Vogt, B., Mushack, J., Setter, E. and Haring, H. U. (1991) Biochem. J. 275, 597-600
32. Galante, P., Mosthaf, L., Keller M., Berti, L., Tippner, S., Bossenmaier, B., Fujiwara, T., Okuno, A., Horikoshi, H. and Haring, H. U. (1995) Diabetes 44, 646-651