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Volumn 31, Issue 11, 1996, Pages 1141-1149

Chronic free fatty acid infusion in rats results in insulin resistance but no alteration in insulin-responsive glucose transporter levels in skeletal muscle

Author keywords

[No Author keywords available]

Indexed keywords

FATTY ACID; GLUCOSE TRANSPORTER; INSULIN; INTRALIPID;

EID: 0029955825     PISSN: 00244201     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02524288     Document Type: Article
Times cited : (24)

References (34)
  • 1
    • 0013772629 scopus 로고
    • Regulation of Glucose Uptake by Muscle. Effects of Fatty Acids, Ketone Bodies, and Pyruvate Anbdof Alloxan-Diabetes and Starvation on the Uptake and Metabolic Fate of Glucose in Rat Heart and Diaphgram Muscles
    • Randle, P., Newsholme, E., and Garland, P. (1964) Regulation of Glucose Uptake by Muscle. Effects of Fatty Acids, Ketone Bodies, and Pyruvate Anbdof Alloxan-Diabetes and Starvation on the Uptake and Metabolic Fate of Glucose in Rat Heart and Diaphgram Muscles, Biochem. J. 93, 652-665.
    • (1964) Biochem. J. , vol.93 , pp. 652-665
    • Randle, P.1    Newsholme, E.2    Garland, P.3
  • 5
    • 0024323127 scopus 로고
    • Impairment of Glucose Disposal by Infusion of Triglycerides in Humans: Role of Glycemia
    • Feley, C., Felley, E., Van Mele, G., Frascarolo, P., Jequier, E., and Felber, J. (1989) Impairment of Glucose Disposal by Infusion of Triglycerides in Humans: Role of Glycemia, Am. J. Physiol. 256, E747-E752.
    • (1989) Am. J. Physiol. , vol.256
    • Feley, C.1    Felley, E.2    Van Mele, G.3    Frascarolo, P.4    Jequier, E.5    Felber, J.6
  • 7
    • 0023908033 scopus 로고
    • Effect of Elevated Free Fatty Acids on Glucose Oxidation in Normal Humans
    • Wolfe, B., Klein, S., Peters, E., Schmidt, B., and Wolfe, R. (1988) Effect of Elevated Free Fatty Acids on Glucose Oxidation in Normal Humans, Metab. Clin. Exp. 37, 323-329.
    • (1988) Metab. Clin. Exp. , vol.37 , pp. 323-329
    • Wolfe, B.1    Klein, S.2    Peters, E.3    Schmidt, B.4    Wolfe, R.5
  • 8
    • 0025779641 scopus 로고
    • Role of Free Fatty Acids in Hepatic Insulin Resistance during Late Pregnancy in Conscious Rabbits
    • Gilbert, M., Pere, M., Baudelin, A., and Battaglia, F. (1991) Role of Free Fatty Acids in Hepatic Insulin Resistance During Late Pregnancy in Conscious Rabbits, Am. J. Physiol. 260, E938-E945.
    • (1991) Am. J. Physiol. , vol.260
    • Gilbert, M.1    Pere, M.2    Baudelin, A.3    Battaglia, F.4
  • 9
    • 0025766692 scopus 로고
    • Palmitate Stimulates Glucose Transport in Rat Adipocytes by a Mechanism Involving Translocation of the Insulin Sensitive Glucose Transporter (GLUT4)
    • Hardy, R., Ladenson, J., Henriksen, E., Holloszy, J., and McDonald, J. (1991) Palmitate Stimulates Glucose Transport in Rat Adipocytes by a Mechanism Involving Translocation of the Insulin Sensitive Glucose Transporter (GLUT4), Biochem. Biophys. Res. Comm. 177, 343-349.
    • (1991) Biochem. Biophys. Res. Comm. , vol.177 , pp. 343-349
    • Hardy, R.1    Ladenson, J.2    Henriksen, E.3    Holloszy, J.4    McDonald, J.5
  • 10
    • 0023739445 scopus 로고
    • Effects of Nonesterified Fatty Acid Availability on Tissue-Specific Glucose Utilization in Rats in vivo
    • Jenkins, A., Storlien, L., Chisholm. D., and Kraegen, E. (1988) Effects of Nonesterified Fatty Acid Availability on Tissue-Specific Glucose Utilization in Rats in vivo, J. Clin. Invest. 82, 293-299.
    • (1988) J. Clin. Invest. , vol.82 , pp. 293-299
    • Jenkins, A.1    Storlien, L.2    Chisholm, D.3    Kraegen, E.4
  • 12
    • 0019843433 scopus 로고
    • Hyperglycemia Induced by Glucose Infusion in the Unrestained Pregnant Rat during the Last Three Days of Gestation: Metabolic and Hormonal Changes in the Mother and the Fetus
    • Ktorza, A., Girard, J., Kinebanyan, M., and Picon, L. (1981) Hyperglycemia Induced by Glucose Infusion in the Unrestained Pregnant Rat During the Last Three Days of Gestation: Metabolic and Hormonal Changes in the Mother and the Fetus, Diabetologia 21, 569-574.
    • (1981) Diabetologia , vol.21 , pp. 569-574
    • Ktorza, A.1    Girard, J.2    Kinebanyan, M.3    Picon, L.4
  • 13
    • 0019510887 scopus 로고
    • Glucose Turnover during Pregnancy in Anesthetized Post Absorptive Rats
    • Leturque, A., Gilbert, M., and Girard, J. (1981) Glucose Turnover During Pregnancy in Anesthetized Post Absorptive Rats, Biochem. J. 196, 633-636.
    • (1981) Biochem. J. , vol.196 , pp. 633-636
    • Leturque, A.1    Gilbert, M.2    Girard, J.3
  • 14
    • 0021839186 scopus 로고
    • A Method to Quantify Glucose Utilization in vivo in Skeletal Muscle and White Adipose Tissue of the Anesthetized Rat
    • Ferré, P., Leturque, A., Burnol, A., and Girard, J. (1985) A Method to Quantify Glucose Utilization in vivo in Skeletal Muscle and White Adipose Tissue of the Anesthetized Rat, Biochem. J. 228, 103-110.
    • (1985) Biochem. J. , vol.228 , pp. 103-110
    • Ferré, P.1    Leturque, A.2    Burnol, A.3    Girard, J.4
  • 16
    • 0016372843 scopus 로고
    • Direct Enzymatic Procedure for the Determination of Liver Glycogen
    • Roehrig, K., and Allred, J. (1974) Direct Enzymatic Procedure for the Determination of Liver Glycogen, Anal. Biochem. 58, 414-421.
    • (1974) Anal. Biochem. , vol.58 , pp. 414-421
    • Roehrig, K.1    Allred, J.2
  • 17
    • 0025835909 scopus 로고
    • Effect of Free Fatty Acids on Glucose Uptake and Nonoxidative Glycolysis Across Human Forearm Tissues in the Basal State and during Insulin Stimulation
    • Yki-Järvinen, H., Puhakainen, I., and Koivisto, A. (1991) Effect of Free Fatty Acids on Glucose Uptake and Nonoxidative Glycolysis Across Human Forearm Tissues in the Basal State and During Insulin Stimulation, J. Clin. Endocrinol. Metab. 78, 1268-1277.
    • (1991) J. Clin. Endocrinol. Metab. , vol.78 , pp. 1268-1277
    • Yki-Järvinen, H.1    Puhakainen, I.2    Koivisto, A.3
  • 18
    • 0024392514 scopus 로고
    • Glucose and Free Fatty Acid Metabolism in Non-Insulin-Dependent Diabetes Mellitus: Evidence for Multiple Sites of Insulin Resistance
    • Groop, L., Bonadona, R., Del Prato, S., Ratheiser, K., Zyck, K., Ferranini, E., and De Fronzo, R. (1989) Glucose and Free Fatty Acid Metabolism in Non-Insulin-Dependent Diabetes Mellitus: Evidence for Multiple Sites of Insulin Resistance, J. Clin. Inves. 84, 205-213.
    • (1989) J. Clin. Inves. , vol.84 , pp. 205-213
    • Groop, L.1    Bonadona, R.2    Del Prato, S.3    Ratheiser, K.4    Zyck, K.5    Ferranini, E.6    De Fronzo, R.7
  • 19
    • 0020525584 scopus 로고
    • Stimulation of Gluconeogenesis by Palmitic Acid in Rat Hepatocytes: Evidence That This Effect Can Be Dissociated from the Provisions of Reducing Equivalents
    • Blumenthal, S.A. (1983) Stimulation of Gluconeogenesis by Palmitic Acid in Rat Hepatocytes: Evidence That This Effect Can Be Dissociated from the Provisions of Reducing Equivalents, Metab. Clin. Exp. 32, 971-976.
    • (1983) Metab. Clin. Exp. , vol.32 , pp. 971-976
    • Blumenthal, S.A.1
  • 20
    • 0023913990 scopus 로고
    • Palmitate Inhibits Liver Glycolysis
    • Hue, L., Maisin, L., and Rider, M. (1988) Palmitate Inhibits Liver Glycolysis, Biochem. J. 251, 541-545.
    • (1988) Biochem. J. , vol.251 , pp. 541-545
    • Hue, L.1    Maisin, L.2    Rider, M.3
  • 21
    • 0013923479 scopus 로고
    • Mechanism for the Stimulation of Gluconeogenesis by Fatty Acids in Perfused Rat Liver
    • Williamson, J., Kreisberg, R., and Felts, P. (1966) Mechanism for the Stimulation of Gluconeogenesis by Fatty Acids in Perfused Rat Liver, Proc. Natl. Acad. Sci. USA 56, 247-254.
    • (1966) Proc. Natl. Acad. Sci. USA , vol.56 , pp. 247-254
    • Williamson, J.1    Kreisberg, R.2    Felts, P.3
  • 22
    • 0028297306 scopus 로고
    • Saturated Fatty Acid-Induced Insulin Resistance in Rat Adipocytes
    • Hunnicut, J., Hardy, R., Williford, J., and McDonald, J. (1994) Saturated Fatty Acid-Induced Insulin Resistance in Rat Adipocytes, Diabetes 43, 540-545.
    • (1994) Diabetes , vol.43 , pp. 540-545
    • Hunnicut, J.1    Hardy, R.2    Williford, J.3    McDonald, J.4
  • 23
    • 0026808333 scopus 로고
    • Effects of Oleate and Insulin on Glucose Uptake, Oxidation, and Glucose Transporter Proteins in Rat Adipocytes
    • Murer, E., Boden, G., Gyda, M., and Deluca, F. (1992) Effects of Oleate and Insulin on Glucose Uptake, Oxidation, and Glucose Transporter Proteins in Rat Adipocytes, Diabetes 41, 1063-1068.
    • (1992) Diabetes , vol.41 , pp. 1063-1068
    • Murer, E.1    Boden, G.2    Gyda, M.3    Deluca, F.4
  • 24
    • 0028342686 scopus 로고
    • Mechanisms of Fatty Acid-Induced Inhibition of Glucose Uptake
    • Boden, G., Chen, X., Ruiz, J., White, J., and Rossetti, L. (1994) Mechanisms of Fatty Acid-Induced Inhibition of Glucose Uptake, J. Clin. Invest. 93, 2438-2446.
    • (1994) J. Clin. Invest. , vol.93 , pp. 2438-2446
    • Boden, G.1    Chen, X.2    Ruiz, J.3    White, J.4    Rossetti, L.5
  • 25
    • 0029084869 scopus 로고
    • Effects of Fat on Glucose Uptake and Utilization in Patients with Noninsulin-Dependent Diabetes
    • Boden, G., and Chen, X. (1995) Effects of Fat on Glucose Uptake and Utilization in Patients with Noninsulin-Dependent Diabetes, J. Clin. Invest. 96, 1261-1268.
    • (1995) J. Clin. Invest. , vol.96 , pp. 1261-1268
    • Boden, G.1    Chen, X.2
  • 27
    • 0017776141 scopus 로고
    • Inhibition of Glucose Uptake and Glycogenolysis by Availability of Oleate in Well-Oxygenated Perfused Skeletal Muscle
    • Rennie, M., and Holloszy, J. (1977) Inhibition of Glucose Uptake and Glycogenolysis by Availability of Oleate in Well-Oxygenated Perfused Skeletal Muscle, Biochem. J. 168, 161-170.
    • (1977) Biochem. J. , vol.168 , pp. 161-170
    • Rennie, M.1    Holloszy, J.2
  • 28
    • 0025187661 scopus 로고
    • Glucose Transporter Protein Content and Glucose Transport Activity in Rat Skeletal Muscles
    • Henriksen, E., Bourey, R., Rodnick, K., Koranyi, L., Permutt, M., and Holloszy, J. (1990) Glucose Transporter Protein Content and Glucose Transport Activity in Rat Skeletal Muscles, Am. J. Physiol. 259, E593-598.
    • (1990) Am. J. Physiol. , vol.259
    • Henriksen, E.1    Bourey, R.2    Rodnick, K.3    Koranyi, L.4    Permutt, M.5    Holloszy, J.6
  • 29
    • 0026634984 scopus 로고
    • Peripheral Glucose Uptake and Skeletal Muscle GLUT4 Content in Man: Effect of Insulin and Free Fatty Acids
    • Handberg, A., Vaag, A., Beck-Nielsen, H., and Vinten, J. (1992) Peripheral Glucose Uptake and Skeletal Muscle GLUT4 Content in Man: Effect of Insulin and Free Fatty Acids, Diabetes Med. 9, 605-610.
    • (1992) Diabetes Med. , vol.9 , pp. 605-610
    • Handberg, A.1    Vaag, A.2    Beck-Nielsen, H.3    Vinten, J.4
  • 30
    • 0025266357 scopus 로고
    • Metabolic Conseqences of Hyperinsulinemia Imposed on Normal Rats on Glucose Handling by Adipose Tissue, Muscles and Liver
    • Cusin, I., Terretaz, J., Rohner-Jeanrenaud, F., and Jeanrenaud, B. (1990a) Metabolic Conseqences of Hyperinsulinemia Imposed on Normal Rats on Glucose Handling by Adipose Tissue, Muscles and Liver, Biochem. J. 267, 99-103.
    • (1990) Biochem. J. , vol.267 , pp. 99-103
    • Cusin, I.1    Terretaz, J.2    Rohner-Jeanrenaud, F.3    Jeanrenaud, B.4
  • 31
    • 0025685421 scopus 로고
    • Hyperinsulinemia Increases the Amount of GLUT4 mRNA in White Adipose Tissue and Decreases That of Muscles: A Clue for Increased Fat Depot and Insulin Resistance
    • Cusin, I., Terretaz, J., Rohner-Jeanrenaud, F., Zarjevsky, N., Assimacompoulos-Jeannet, F., and Jeanrenaud, B. (1990b) Hyperinsulinemia Increases the Amount of GLUT4 mRNA in White Adipose Tissue and Decreases That of Muscles: A Clue for Increased Fat Depot and Insulin Resistance, Endocrinology 127, 3246-3248.
    • (1990) Endocrinology , vol.127 , pp. 3246-3248
    • Cusin, I.1    Terretaz, J.2    Rohner-Jeanrenaud, F.3    Zarjevsky, N.4    Assimacompoulos-Jeannet, F.5    Jeanrenaud, B.6
  • 32
    • 0026317768 scopus 로고
    • Divergence between GLUT4 mRNA and Protein Abundance in Skeletal Muscle of Insulin-Resistant Rats
    • Hager, S., Pastorek, D., Jochen, A., and Meier, D. (1991) Divergence Between GLUT4 mRNA and Protein Abundance in Skeletal Muscle of Insulin-Resistant Rats, Biochem. Biophys. Res. Comm. 181, 240-245.
    • (1991) Biochem. Biophys. Res. Comm. , vol.181 , pp. 240-245
    • Hager, S.1    Pastorek, D.2    Jochen, A.3    Meier, D.4
  • 33
    • 0025147293 scopus 로고
    • Expression of Insulin Regulatable Glucose Transporters in Skeletal Muscle from Type 2 (noninsulin-dependent) Diabetic Patients
    • Handberg, A., Vaag, A., Damsbo, P., Beck-Nielsen, H., and Vinten, J. (1990) Expression of Insulin Regulatable Glucose Transporters in Skeletal Muscle from Type 2 (noninsulin-dependent) Diabetic Patients, Diabetologia 33, 625-627.
    • (1990) Diabetologia , vol.33 , pp. 625-627
    • Handberg, A.1    Vaag, A.2    Damsbo, P.3    Beck-Nielsen, H.4    Vinten, J.5
  • 34
    • 0025302915 scopus 로고
    • Evidence Against Altered Expresion of GLUT1 or GLUT4 in Skeletal Muscle of Patients with Obesity of NIDDM
    • Pedersen, O., Bak, J., Andersen, P., Lund, S., Moller, D., Flier, J., and Kahn, B. (1990) Evidence Against Altered Expresion of GLUT1 or GLUT4 in Skeletal Muscle of Patients with Obesity of NIDDM, Diabetes 39, 865-870.
    • (1990) Diabetes , vol.39 , pp. 865-870
    • Pedersen, O.1    Bak, J.2    Andersen, P.3    Lund, S.4    Moller, D.5    Flier, J.6    Kahn, B.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.