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Volumn 42, Issue 4, 1999, Pages 419-426

Features of syndrome X develop in transgenic rats expressing a non- insulin responsive phosphoenolpyruvate carboxykinase gene

Author keywords

Cholesterol; Glucose; Insulin; Insulin resistance; Obesity; Phosphoenolpyruvate carboxykinase; Syndrome X; Transgenic rats; Triglycerides

Indexed keywords

CHOLESTEROL; GLUCOSE; INSULIN; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); TRIACYLGLYCEROL;

EID: 0033015491     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001250051174     Document Type: Article
Times cited : (19)

References (36)
  • 1
    • 0024160877 scopus 로고
    • Role of insulin resistance in human disease
    • Reaven G (1988) Role of insulin resistance in human disease. Diabetes 37: 1595-1607
    • (1988) Diabetes , vol.37 , pp. 1595-1607
    • Reaven, G.1
  • 2
    • 0024391834 scopus 로고
    • The deadly quartet. Upper body obesity, glucose intolerance, hypertriglyceridemia and hypertension
    • Kaplan NM (1989) The deadly quartet. Upper body obesity, glucose intolerance, hypertriglyceridemia and hypertension. Arch Intern Med 149: 1514-1520
    • (1989) Arch Intern Med , vol.149 , pp. 1514-1520
    • Kaplan, N.M.1
  • 3
    • 0030731621 scopus 로고    scopus 로고
    • NIDDM as a disease of the innate immune system: Association of acute-phase reactants and interleukin-6 with metabolic syndrome X
    • Pickup JC, Mattock MB, Chusney GD, Burt D (1997) NIDDM as a disease of the innate immune system: association of acute-phase reactants and interleukin-6 with metabolic syndrome X. Diabetologia 40: 1286-1292
    • (1997) Diabetologia , vol.40 , pp. 1286-1292
    • Pickup, J.C.1    Mattock, M.B.2    Chusney, G.D.3    Burt, D.4
  • 4
    • 0025780331 scopus 로고
    • Hyperinsulinaemia: The key feature of a cardiovascular and metabolic syndrome
    • Ferrannini E, Haffner SM, Mitchell BD, Stern MP (1991) Hyperinsulinaemia: the key feature of a cardiovascular and metabolic syndrome. Diabetologia 34: 416-422
    • (1991) Diabetologia , vol.34 , pp. 416-422
    • Ferrannini, E.1    Haffner, S.M.2    Mitchell, B.D.3    Stern, M.P.4
  • 5
    • 0023573935 scopus 로고
    • Prevalence of diabetes and impaired glucose tolerance and plasma glucose levels in U. S. population aged 20-74 years
    • Harris M, Hadden W, Knowler W, Bennett P (1987) Prevalence of diabetes and impaired glucose tolerance and plasma glucose levels in U. S. population aged 20-74 years. Diabetes 36: 523-534
    • (1987) Diabetes , vol.36 , pp. 523-534
    • Harris, M.1    Hadden, W.2    Knowler, W.3    Bennett, P.4
  • 6
    • 0027406191 scopus 로고
    • Diabetes, other risk factors and 12-yr cardiovascular mortality for men screened in the multiple risk factor intervention trial
    • Stamler J, Vaccaro O, Neaton JD, Wentworth D (1993) Diabetes, other risk factors and 12-yr cardiovascular mortality for men screened in the Multiple Risk Factor Intervention Trial. Diabetes Care 16: 434-444
    • (1993) Diabetes Care , vol.16 , pp. 434-444
    • Stamler, J.1    Vaccaro, O.2    Neaton, J.D.3    Wentworth, D.4
  • 7
    • 0030063437 scopus 로고    scopus 로고
    • Genetic and environmental influences on insulin levels and the insulin resistance syndrome: An analysis of women twins
    • Mayer EJ, Newman B, Austin MA et al. (1996) Genetic and environmental influences on insulin levels and the Insulin Resistance Syndrome: an analysis of women twins. Am J Epidemiol 143: 323-332
    • (1996) Am J Epidemiol , vol.143 , pp. 323-332
    • Mayer, E.J.1    Newman, B.2    Austin, M.A.3
  • 8
    • 0030065814 scopus 로고    scopus 로고
    • Genetic analysis of the IRS. Pleiotrophic effects of genes influencing insulin levels on lipoprotein and obesity measures
    • Mitchell BD, Kammerer CM, Mahaney MC et al. (1996) Genetic analysis of the IRS. Pleiotrophic effects of genes influencing insulin levels on lipoprotein and obesity measures. Arterioscler Thromb Vase Biol 16: 281-288
    • (1996) Arterioscler Thromb Vase Biol , vol.16 , pp. 281-288
    • Mitchell, B.D.1    Kammerer, C.M.2    Mahaney, M.C.3
  • 9
    • 0031894423 scopus 로고    scopus 로고
    • Insulin and coronary artery disease: Is syndrome X the unifying hypothesis?
    • Baillie GM, Sherer JT, Weart CW (1998) Insulin and coronary artery disease: is syndrome X the unifying hypothesis? Ann Pharmacother 32: 233-247
    • (1998) Ann Pharmacother , vol.32 , pp. 233-247
    • Baillie, G.M.1    Sherer, J.T.2    Weart, C.W.3
  • 10
    • 0031952565 scopus 로고    scopus 로고
    • Hyperinsulinemia is associated with the incidence of hypertension and dyslipidemia in middle-aged men
    • Salonen JT, Lakka TA, Lakka HM, Valkonen VP, Everson SA, Kaplan GA (1998) Hyperinsulinemia is associated with the incidence of hypertension and dyslipidemia in middle-aged men. Diabetes 47: 270-275
    • (1998) Diabetes , vol.47 , pp. 270-275
    • Salonen, J.T.1    Lakka, T.A.2    Lakka, H.M.3    Valkonen, V.P.4    Everson, S.A.5    Kaplan, G.A.6
  • 12
    • 0025266357 scopus 로고
    • Metabolic consequences of hyperinsulinemia imposed on normal rats on glucose handling by white adipose tissue, muscles and liver
    • Cusin I, Terrettaz J, Rohner-Jeanrenaud F, Jeanrenaud B (1990) Metabolic consequences of hyperinsulinemia imposed on normal rats on glucose handling by white adipose tissue, muscles and liver. Biochem J 267: 99-103
    • (1990) Biochem J , vol.267 , pp. 99-103
    • Cusin, I.1    Terrettaz, J.2    Rohner-Jeanrenaud, F.3    Jeanrenaud, B.4
  • 14
    • 0031944104 scopus 로고    scopus 로고
    • Diet-induced insulin resistance precedes other aspects of the metabolic syndrome
    • Barnard RJ, Roberts CK, Varon SM, Berger JJ (1998) Diet-induced insulin resistance precedes other aspects of the metabolic syndrome. J Appl Physiol 84: 1311-1315
    • (1998) J Appl Physiol , vol.84 , pp. 1311-1315
    • Barnard, R.J.1    Roberts, C.K.2    Varon, S.M.3    Berger, J.J.4
  • 15
    • 0031848802 scopus 로고    scopus 로고
    • Birth weight and the future development of diabetes. A review of the evidence
    • Phillips DI (1998) Birth weight and the future development of diabetes. A review of the evidence. Diabetes Care 21 [Suppl 2]: B 150-155
    • (1998) Diabetes Care , vol.21 B , Issue.SUPPL. 2 , pp. 150-155
    • Phillips, D.I.1
  • 17
    • 0029742775 scopus 로고    scopus 로고
    • Hexosamines and insulin resistance
    • McClain DA, Crook ED (1996) Hexosamines and insulin resistance. Diabetes 45: 1003-1009
    • (1996) Diabetes , vol.45 , pp. 1003-1009
    • McClain, D.A.1    Crook, E.D.2
  • 18
    • 0024402180 scopus 로고
    • Mechanisms underlying regional differences in lipolysis in human adipose tissue
    • Wahrenberg H, Lonnqvist F, Arner P (1989) Mechanisms underlying regional differences in lipolysis in human adipose tissue. J Clin Invest 84: 458-67
    • (1989) J Clin Invest , vol.84 , pp. 458-467
    • Wahrenberg, H.1    Lonnqvist, F.2    Arner, P.3
  • 19
    • 0023739445 scopus 로고
    • Effects of nonesterified fatty acid availability on tissue-specific glucose utilization in rats in vivo
    • Jenkins AB, Storlien LH, Chisholm DJ, Kraegen EW (1988) Effects of nonesterified fatty acid availability on tissue-specific glucose utilization in rats in vivo. J Clin Invest 82: 293-299
    • (1988) J Clin Invest , vol.82 , pp. 293-299
    • Jenkins, A.B.1    Storlien, L.H.2    Chisholm, D.J.3    Kraegen, E.W.4
  • 20
    • 0029046673 scopus 로고
    • Effects of a 48-h fat infusion on insulin secretion and glucose utilization
    • Boden G, Chen X, Rosner J, Barton M (1995) Effects of a 48-h fat infusion on insulin secretion and glucose utilization. Diabetes 44: 1239-1242
    • (1995) Diabetes , vol.44 , pp. 1239-1242
    • Boden, G.1    Chen, X.2    Rosner, J.3    Barton, M.4
  • 21
    • 0029915937 scopus 로고    scopus 로고
    • Impaired regulation of hepatic fructose-1,6-bisphosphatase in the New Zealand Obese mouse: An acquired defect
    • Andrikopoulos S, Rosella G, Kaczmarczyk S, Zajac J, Proietto J (1996) Impaired regulation of hepatic fructose-1,6-bisphosphatase in the New Zealand Obese mouse: An acquired defect. Metabolism 45: 622-626
    • (1996) Metabolism , vol.45 , pp. 622-626
    • Andrikopoulos, S.1    Rosella, G.2    Kaczmarczyk, S.3    Zajac, J.4    Proietto, J.5
  • 22
    • 0029098648 scopus 로고
    • Impaired glucose tolerance and increased weight gain in transgenic rats overexpressing a non-insulin responsive phosphoenolpyruvate carboxykinase gene
    • Rosella G, Zajac JD, Baker L et al. (1995) Impaired glucose tolerance and increased weight gain in transgenic rats overexpressing a non-insulin responsive phosphoenolpyruvate carboxykinase gene. Mol Endocrinol 9: 1396-1404
    • (1995) Mol Endocrinol , vol.9 , pp. 1396-1404
    • Rosella, G.1    Zajac, J.D.2    Baker, L.3
  • 23
    • 25544444438 scopus 로고    scopus 로고
    • Insulin inhibits gluconeogenesis predominantly through suppression of phosphoenolpyruvate carboxykinase
    • Dickens RA, Rosella G, Zajac J, Proietto J (1997) Insulin inhibits gluconeogenesis predominantly through suppression of phosphoenolpyruvate carboxykinase. Diabetologia 40: A 24
    • (1997) Diabetologia , vol.40
    • Dickens, R.A.1    Rosella, G.2    Zajac, J.3    Proietto, J.4
  • 24
    • 0016373654 scopus 로고
    • Enzymatic determination of total serum cholesterol
    • Allain C, Poon L, Chan C, Richmond W, Fu P (1974) Enzymatic determination of total serum cholesterol. Clin Chem 20: 470-475
    • (1974) Clin Chem , vol.20 , pp. 470-475
    • Allain, C.1    Poon, L.2    Chan, C.3    Richmond, W.4    Fu, P.5
  • 25
    • 0018424273 scopus 로고
    • Manual and continuous-flow colorimetry of triacylglycerols by a fully enzymic method
    • Megraw R, Dunn D, Biggs H (1979) Manual and continuous-flow colorimetry of triacylglycerols by a fully enzymic method. Clin Chem 25: 273-278
    • (1979) Clin Chem , vol.25 , pp. 273-278
    • Megraw, R.1    Dunn, D.2    Biggs, H.3
  • 26
    • 0032523085 scopus 로고    scopus 로고
    • Hypertension, hypertriglyceridemia, and impaired endothelium-dependent vascular relaxation in mice lacking insulin receptor substrate-1
    • Abe H, Yamada N, Kamata K et al. (1998) Hypertension, hypertriglyceridemia, and impaired endothelium-dependent vascular relaxation in mice lacking insulin receptor substrate-1. J Clin Invest 101: 1784-1788
    • (1998) J Clin Invest , vol.101 , pp. 1784-1788
    • Abe, H.1    Yamada, N.2    Kamata, K.3
  • 27
    • 0030041766 scopus 로고    scopus 로고
    • Examination of the phosphoenolpyruvate carboxykinase gene promoter in patients with noninsulin-dependent diabetes mellitus
    • Ludwig DS, Vidal-Puig A, O'Brien RM et al. (1996) Examination of the phosphoenolpyruvate carboxykinase gene promoter in patients with noninsulin-dependent diabetes mellitus. J Clin Endocrinol Metab 81: 503-506
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 503-506
    • Ludwig, D.S.1    Vidal-Puig, A.2    O'Brien, R.M.3
  • 28
    • 0030804019 scopus 로고    scopus 로고
    • Insulin receptor substrate-1 gene polymorphism and cardiovascular risk in non-insulin dependent diabetes mellitus and patients undergoing coronary angiography
    • Ossei-Gerning N, Mansfield MW, Stickland MH, Grant PJ (1997) Insulin receptor substrate-1 gene polymorphism and cardiovascular risk in non-insulin dependent diabetes mellitus and patients undergoing coronary angiography. Clin Lab Haematol 19: 123-128
    • (1997) Clin Lab Haematol , vol.19 , pp. 123-128
    • Ossei-Gerning, N.1    Mansfield, M.W.2    Stickland, M.H.3    Grant, P.J.4
  • 29
    • 0030059853 scopus 로고    scopus 로고
    • The pathogenesis of type II diabetes mellitus - A polygenic disease
    • Sacks D, McDonald J (1996) The pathogenesis of Type II diabetes mellitus - a polygenic disease. Am J Clin Pathol 105: 149-156
    • (1996) Am J Clin Pathol , vol.105 , pp. 149-156
    • Sacks, D.1    McDonald, J.2
  • 30
    • 0027092522 scopus 로고
    • Abdominal obesity and the metabolic syndrome
    • Bjorntorp P (1994) Abdominal obesity and the metabolic syndrome. Ann Med 24: 465-468
    • (1994) Ann Med , vol.24 , pp. 465-468
    • Bjorntorp, P.1
  • 31
    • 0027496056 scopus 로고
    • Abdominal obesity as an important component of insulin-resistance syndrome
    • Despres JP (1993) Abdominal obesity as an important component of insulin-resistance syndrome. Nutrition 9: 452-459
    • (1993) Nutrition , vol.9 , pp. 452-459
    • Despres, J.P.1
  • 32
    • 0028695552 scopus 로고
    • Hyperinsulinemia and hypertriglyceridaemia
    • Steiner G (1994) Hyperinsulinemia and hypertriglyceridaemia. J Intern Med 236 [Suppl 736]: 23-26
    • (1994) J Intern Med , vol.236 , Issue.SUPPL. 736 , pp. 23-26
    • Steiner, G.1
  • 33
    • 0030835994 scopus 로고    scopus 로고
    • Relationship between insulin-mediated glucose disposal and regulation of plasma and adipose tissue lipoprotein lipase
    • Maheux P, Azhar S, Kern PA, Chen YD, Reaven GM (1997) Relationship between insulin-mediated glucose disposal and regulation of plasma and adipose tissue lipoprotein lipase. Diabetologia 40: 850-858
    • (1997) Diabetologia , vol.40 , pp. 850-858
    • Maheux, P.1    Azhar, S.2    Kern, P.A.3    Chen, Y.D.4    Reaven, G.M.5
  • 34
    • 0026021161 scopus 로고
    • Insulin resistance - A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease
    • DeFronzo R, Ferrannini E (1991) Insulin resistance - a multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease. Diabetes Care 14: 173-194
    • (1991) Diabetes Care , vol.14 , pp. 173-194
    • DeFronzo, R.1    Ferrannini, E.2
  • 35
    • 0030657907 scopus 로고    scopus 로고
    • Reduced insulin receptor signalling in the obese spontaneously hypertensive Koletsky rat
    • Friedman JE, Ishizuka T, Liu S et al. (1997) Reduced insulin receptor signalling in the obese spontaneously hypertensive Koletsky rat. Am J Physiol 273: E1014-E1023
    • (1997) Am J Physiol , vol.273
    • Friedman, J.E.1    Ishizuka, T.2    Liu, S.3
  • 36
    • 0031957393 scopus 로고    scopus 로고
    • Obesity induced by neonatal monosodium glutamate treatment in spontaneously hypertensive rats: An animal model of multiple risk factors
    • Iwase M, Yamamoto M, Iino K et al. (1998) Obesity induced by neonatal monosodium glutamate treatment in spontaneously hypertensive rats: an animal model of multiple risk factors. Hypertens Res 21: 1-6
    • (1998) Hypertens Res , vol.21 , pp. 1-6
    • Iwase, M.1    Yamamoto, M.2    Iino, K.3


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