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Volumn 97, Issue 2, 1996, Pages 646-654

A controlled trial of the effect of the 5-lipoxygenase inhibitor, zileuton, on lung inflammation produced by segmental antigen challenge in human beings

Author keywords

5 lipoxygenase; bronchoalveolar lavage; cysteinyl leukotrienes; eosinophil; IgE mediated inflammation; leukotriene B4; neutrophil; SAC of the lung; zileuton

Indexed keywords

IMMUNOGLOBULIN E; LEUKOTRIENE; ZILEUTON;

EID: 0030033328     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-6749(96)70310-X     Document Type: Article
Times cited : (120)

References (31)
  • 1
    • 0026525375 scopus 로고
    • Effect of antigen dose on the recruitment of inflammatory cells to the lungs by segmental antigen challenge
    • Dupuis R, Collins DS, Koh YY, et al. Effect of antigen dose on the recruitment of inflammatory cells to the lungs by segmental antigen challenge. J ALLERGY CLIN IMMUNOL 1992;89:850-7.
    • (1992) J Allergy Clin Immunol , vol.89 , pp. 850-857
    • Dupuis, R.1    Collins, D.S.2    Koh, Y.Y.3
  • 2
  • 4
    • 0026336565 scopus 로고
    • Immediate and late airway response of allergic rhinitis patients to segmental antigen challenge: Characterization of eosinophil and mast cell mediators
    • Sedgwick JB, Calhoun WJ, Gleich GI, et al. Immediate and late airway response of allergic rhinitis patients to segmental antigen challenge: characterization of eosinophil and mast cell mediators. Am Rev Respir Dis 1991;144:1274-81.
    • (1991) Am Rev Respir Dis , vol.144 , pp. 1274-1281
    • Sedgwick, J.B.1    Calhoun, W.J.2    Gleich, G.I.3
  • 5
    • 0027419677 scopus 로고
    • Immunoglobulin E-mediated increase in vascular permeability correlates with eosinophil inflammation
    • Collins DS, Dupuis R, Gleick GJ, et al. Immunoglobulin E-mediated increase in vascular permeability correlates with eosinophil inflammation. Am Rev Respir Dis 1993; 147:677-83.
    • (1993) Am Rev Respir Dis , vol.147 , pp. 677-683
    • Collins, D.S.1    Dupuis, R.2    Gleick, G.J.3
  • 6
    • 0019311062 scopus 로고
    • Leukotriene B, a potent chemotactic and aggregatory substance released from polymorphonuclear leukocytes
    • Ford-Hutchinson AW, Bray MA, Doig MV, Shipley ME, Smith MJH. Leukotriene B, a potent chemotactic and aggregatory substance released from polymorphonuclear leukocytes. Nature 1980;286:264-5.
    • (1980) Nature , vol.286 , pp. 264-265
    • Ford-Hutchinson, A.W.1    Bray, M.A.2    Doig, M.V.3    Shipley, M.E.4    Smith, M.J.H.5
  • 8
    • 0020597565 scopus 로고
    • Leukotrienes: Mediators of immediate hypersensitiyity reactions and inflammation
    • Samuelsson B. Leukotrienes: mediators of immediate hypersensitiyity reactions and inflammation. Science 1983; 220:568-75.
    • (1983) Science , vol.220 , pp. 568-575
    • Samuelsson, B.1
  • 13
    • 0025647031 scopus 로고
    • The effects of a 5-lipoxygenase inhibitor on asthma induced by cold, dry air
    • Israel E, Dermarkarian R, Rosenberg M, et al. The effects of a 5-lipoxygenase inhibitor on asthma induced by cold, dry air. N Engl J Med 1990;323:1740-4.
    • (1990) N Engl J Med , vol.323 , pp. 1740-1744
    • Israel, E.1    Dermarkarian, R.2    Rosenberg, M.3
  • 14
    • 0025685169 scopus 로고
    • Reduced allergen-induced nasal congestion and leukotriene synthesis with an orally active 5-lipoxygenase inhibitor
    • Knapp HR. Reduced allergen-induced nasal congestion and leukotriene synthesis with an orally active 5-lipoxygenase inhibitor. N Engl J Med 1990;323:1745-8.
    • (1990) N Engl J Med , vol.323 , pp. 1745-1748
    • Knapp, H.R.1
  • 15
    • 0024805189 scopus 로고
    • Intraluminal airway inflammation in chronic bronchitis: Characterization and correlation with clinical parameters
    • Thompson AB, Daughton D, Robbins RA, Ghafouri MA, Oehlerking M, Rennard SI. Intraluminal airway inflammation in chronic bronchitis: characterization and correlation with clinical parameters. Am Rev Respir Dis 1989;140: 1527-37.
    • (1989) Am Rev Respir Dis , vol.140 , pp. 1527-1537
    • Thompson, A.B.1    Daughton, D.2    Robbins, R.A.3    Ghafouri, M.A.4    Oehlerking, M.5    Rennard, S.I.6
  • 17
    • 72949127206 scopus 로고
    • A rapid and precise method for the determination of urea
    • Fawcett JK, Scott JE. A rapid and precise method for the determination of urea. J Clin Pathol 1960;13:156-9.
    • (1960) J Clin Pathol , vol.13 , pp. 156-159
    • Fawcett, J.K.1    Scott, J.E.2
  • 18
    • 33646400526 scopus 로고
    • Modified reagents for the estimation of ammonia in plasma
    • Chancy AL, Marback EP. Modified reagents for the estimation of ammonia in plasma. Clin Chem 1962;8:130-2.
    • (1962) Clin Chem , vol.8 , pp. 130-132
    • Chancy, A.L.1    Marback, E.P.2
  • 19
    • 0023687360 scopus 로고
    • Assessment of the sources of protein in methacholine-induced nasal secretions
    • Raphael GD, Druce HM, Baraniuk JN, Kaliner MA. Assessment of the sources of protein in methacholine-induced nasal secretions. Am Rev Respir Dis 1988;138:413-20.
    • (1988) Am Rev Respir Dis , vol.138 , pp. 413-420
    • Raphael, G.D.1    Druce, H.M.2    Baraniuk, J.N.3    Kaliner, M.A.4
  • 20
    • 0026332275 scopus 로고
    • Pharmacokinetics, safety, and ability to diminish leukotriene synthesis by zileuton, an inhibitor of 5-lipoxygenase
    • Basel: Birkhäuser Verlag
    • Rubin P, Dubé L, Braeckman R, et al. Pharmacokinetics, safety, and ability to diminish leukotriene synthesis by zileuton, an inhibitor of 5-lipoxygenase. In: Progress in inflammation research and therapy. Basel: Birkhäuser Verlag, 1991:103-16.
    • (1991) Progress in Inflammation Research and Therapy , pp. 103-116
    • Rubin, P.1    Dubé, L.2    Braeckman, R.3
  • 21
    • 0024522507 scopus 로고
    • Measurement of human urinary leukotrienes by reversed-phase liquid chromatography and radioimmunoassay
    • Tagari P, Ethier D, Carry M, et al. Measurement of human urinary leukotrienes by reversed-phase liquid chromatography and radioimmunoassay. Clin Chem 1989;35:388-91.
    • (1989) Clin Chem , vol.35 , pp. 388-391
    • Tagari, P.1    Ethier, D.2    Carry, M.3
  • 22
    • 0024548854 scopus 로고
    • Spectrum of prostanoid release after bronchoalveolar allergen challenge in atopic asthmatics and in control groups. an alteration in the ratio of bronchoconstrictive to bronchoprotective mediators
    • Wenzel SE, Westcott JY, Smith HR, Larsen GL. Spectrum of prostanoid release after bronchoalveolar allergen challenge in atopic asthmatics and in control groups. An alteration in the ratio of bronchoconstrictive to bronchoprotective mediators. Am Rev Respir Dis 1989;139:450-7.
    • (1989) Am Rev Respir Dis , vol.139 , pp. 450-457
    • Wenzel, S.E.1    Westcott, J.Y.2    Smith, H.R.3    Larsen, G.L.4
  • 24
    • 85030196644 scopus 로고    scopus 로고
    • Pulmonary inflammation after segmental ragweed challenge in allergic asthmatics and nonasthmatics
    • in press
    • Shaver JR, O'Connor JJ, Pollice M, et al. Pulmonary inflammation after segmental ragweed challenge in allergic asthmatics and nonasthmatics. Am J Respir Crit Care Med (in press).
    • Am J Respir Crit Care Med
    • Shaver, J.R.1    O'Connor, J.J.2    Pollice, M.3
  • 30
    • 33646965438 scopus 로고
    • Effects of prednisone on the airway inflammation following allergen challenge in subjects with allergic asthma
    • Liu MC, Proud D, Lichtenstein LM, et al. Effects of prednisone on the airway inflammation following allergen challenge in subjects with allergic asthma [Abstract]. Am Rev Respir Dis 1993;147:A521.
    • (1993) Am Rev Respir Dis , vol.147
    • Liu, M.C.1    Proud, D.2    Lichtenstein, L.M.3
  • 31
    • 0027369276 scopus 로고
    • The effect of inhibition of 5-lipoxygenase by zileuton in mild-to-moderate asthma
    • Israel E, Rubin P, Kemp JP, et al. The effect of inhibition of 5-lipoxygenase by zileuton in mild-to-moderate asthma. Ann Intern Med 1993;119:10595-1066.
    • (1993) Ann Intern Med , vol.119 , pp. 10595-11066
    • Israel, E.1    Rubin, P.2    Kemp, J.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.