Cysteinyl leukotriene D4 induced vascular smooth muscle cell proliferation: A possible role in myointimal hyperplasia

Thrombosis and Haemostasis

Volumn 76, Issue 1, 1996, Pages 99-104

  Porreca, Ettore ^a,c   Di Febbo, Concetta ^a   Di Sciullo, Anna ^b   Angelucci, Domenico ^a   Nasuti, Mimmo ^b   Vitullo, Paola ^a   Reale, Marcella ^a   Conti, Pio ^a   Cuccurullo, Franco ^a   Poggi, Andreina ^b  

^a UNIVERSITY OF CHIETI   (Italy)

^b MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^c Ospedale Clinicizzato SS Annunziata   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

LEUKOTRIENE C4; LEUKOTRIENE D4; LEUKOTRIENE E4; VERLUKAST; CYSTEINYL LEUKOTRIENE RECEPTOR 2; LEUKOTRIENE D4 RECEPTOR; LEUKOTRIENE RECEPTOR; LEUKOTRIENE RECEPTOR BLOCKING AGENT; MEMBRANE PROTEIN; PROPIONIC ACID DERIVATIVE; QUINOLINE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY INJURY; ARTERY INTIMA PROLIFERATION; ARTICLE; ATHEROSCLEROSIS; CAROTID ARTERY; CELL COUNT; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA SYNTHESIS; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; VASCULAR SMOOTH MUSCLE; ANIMAL; CELL CULTURE; CELL DIVISION; DRUG EFFECT; HYPERPLASIA; INTIMA; PATHOLOGY;

ANIMALS; CELL DIVISION; CELLS, CULTURED; HYPERPLASIA; LEUKOTRIENE ANTAGONISTS; LEUKOTRIENE D4; MEMBRANE PROTEINS; MUSCLE, SMOOTH, VASCULAR; PROPIONATES; QUINOLINES; RATS; RECEPTORS, LEUKOTRIENE; TUNICA INTIMA;

EID: 0029659031     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0038-1650530     Document Type: Article

References (55)

1. Ross R. The pathogenesis of atherosclerosis - an update. N Engl J Med 1986; 314: 488-500.
2. Ip JH, Fuster V, Badimon L, Badimon J, Taubman MB, Chesebro JH. Syndromes of accelerated atherosclerosis: role of vascular injury and smooth muscle cell proliferation. J Am Coll Cardiol 1990; 15: 1667-87.
3. Ross R. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 1993; 362: 801-9.
4. Munro JM, Cotran RS. The pathogenesis of atherosclerosis: atherogenesis and inflammation. Lab Invest 1988; 58: 249-61.
5. Hansson GK, Jonasson L, Seifert PS, Stemme S. Immune mechanisms in atherosclerosis. Arteriosclerosis 1989; 9: 567-78.
6. Libby P, Hansson GK. Involvement of the immune system in human atherogenesis: current knowledge and unanswered questions. Lab Invest 1991; 64: 5-15.
7. Fagin JA, Forrester JS. Growth factors, cytokines, and vascular injury. Trends Cardiovasc Med 1992; 2: 90-4.
8. Hajjar DP, Pomerantz KB. Signal trasduction in atherosclerosis: integration of cytokines and the eicosanoid network. FASEB J 1992; 6: 2933-41.
9. Lewis RA, Austen KF, Soberman RJ. Leukotrienes and other products of the 5-lipoxygenase pathway. Biochemistry and relation to pathobiology in human diseases. N Engl J Med 1990; 323: 645-55.
10. Murphy RC, Fitzpatrick FA, Maclouf J. Transcellular biosynthesis of eicosanoids and inflammation. In: The Handbook of Inflammation. Mediators of the Inflammatory Process. Henson PM, Murphy RC (eds). Elsevier, Amsterdam 1989; vol 6, pp 147-54.
11. Maclouf J, Murphy RC, Henson PM. Transcellular sulfidopeptide leukotriene biosynthetic capacity of vascular cells. Blood 1989; 74: 703-7.
12. 4 transfer. Trends Pharmacol Sci 1993; 14: 351-4.
13. Leikauf GD, Claesson H-E, Doupnik CA, Hybbinette S, Grafstrom RC. Cysteinyl leukotrienes enhance growth of human airway epithelial cells. Am J Physiol 1990; 259: L255-61.
14. 4 binds to human glomerular epithelial cells and promotes their proliferation in vitro. J Clin Invest 1985; 76: 374-7.
15. Baud L, Perez J, Denis M, Ardaillou R. Modulation of fibroblast proliferation by sulfidopeptide leukotrienes: effect of indomethacin. J Immunol 1987; 138: 1190-5.
16. 4 stimulate DNA synthesis in cultured human epidermal keratinocytes. Br J Dermatol 1985; 113: 43-52.
17. 4: interactions with granulocytemacrophage colony-stimulating factor. Blood 1993; 81: 352-6.
18. Palmberg L, Claesson HE, Thyberg J. Leukotrienes stimulate initiation of DNA synthesis in cultured arterial smooth muscle cells. J Cell Sci 1987; 88: 151-9.
19. Palmberg L, Lindgren JA, Thyberg J, Claesson HE. On the mechanism of induction of DNA synthesis in cultured arterial smooth muscle cells by leukotrienes. Possible role of prostaglandin endoperoxide synthase products and platelet-derived growth factor. J Cell Sci 1991; 98: 141-9.
20. 4 receptor antagonist. Can J Physiol Pharmacol 1989; 67: 17-28.
21. Porreca E, Di Febbo C, Pandolfi A, D'Orazio A, Martelli N, Mezzetti A, Cuccurullo F, Poggi A. Differences in the glutathione system of cultured aortic smooth muscle cells from young and aged rats. Atherosclerosis 1993; 100: 141-8.
22. Porreca E, Ucchino S, Di Febbo C, Di Bartolomeo N, Angelucci D, Napolitano AM, Mezzetti A, Cuccurullo F. Antiproliferative effect of desferrioxamine on vascular smooth muscle cells in vitro and in vivo. Arterioscler Thromb 1994; 14: 299-304.
23. Hanke H, Strohschneider T, Oberhoff M, Betz E, Karsch KR. Time course of smooth muscle cell proliferation in the intima and media of arteries following experimental angioplasty. Circ Res 1990; 67: 651-9.
24. Kolpakov V, Di Sciullo A, Nasuti M, Di Nardo P, Mironov A, Poggi A. Reduced smooth muscle cell regeneration in Yoshida (YOS) spontaneously hypercholesterolemic rats. Atherosclerosis 1994; 111: 227-36.
25. London SM, Mayberg MR. Kinetics of bromodeoxyuridine uptake by smooth muscle cells after arterial injury. J Vasc Res 1994; 31: 247-55.
26. Clowes AW. Prevention and management of recurrent disease after arterial reconstruction: new prospects for pharmacological control. Thromb Haemost 1991; 66: 62-6.
27. Popma JJ, Califf RM, Topol EJ. Clinical trials of restenosis after coronary angioplasty. Circulation 1991; 84: 1426-36.
28. Herrman J-PR, Hermans WRM, Vos J, Serruys PW. Pharmacological approaches to the prevention of restenosis following angioplasty. The search for the holy grail? (part I). Drugs 1993; 46: 18-52.
29. Landau C, Lange RA, Hillis DL. Percutaneous transluminal coronary angioplasty. N Engl J Med 1994; 330: 981-93.
30. 4 on a smooth muscle cell line. J Clin Invest 1983; 72: 1516-9.
31. 4 binding sites in the rat central nervous system. Eur J Pharmacol 1986; 122: 251-7.
32. Gardiner PJ, Abram TS, Tudhope SR, Cuthbert NJ, Norman P, Brink C. Leukotriene receptors and their selective antagonists. Adv Prostaglandin Thromboxane Leukot Res 1994; 22: 49-61.
33. 4-induced signal transduction. Ann NY Acad Sci 1994; 744: 155-60.
34. Allen SP, Chester AH, Dashwood MR, Tadjkarimi S, Piper PJ, Yacoub MH. Preferential vasoconstriction by cysteinyl leukotrienes in the human saphenous vein compared with the internal mammary artery. Implications for graft performance. Circulation 1994; 90: 515-24.
35. Datta YH, Romano M, Jacobson BC, Golan DE, Serhan CN, Ewenstein BM. Peptido-leukotrienes are potent agonists of von Willebrand factor secretion and P-selectin surface expression in human umbilical vein endothelial cells. Circulation 1995; 92: 3304-11.
36. Jawien A, Bowen-Pope DF, Lindner V, Schwartz SM, Clowes AW. Platelet-derived growth factor promotes smooth muscle migration and intima thickening in a rat model of balloon angioplasty. J Clin Invest 1992; 89: 507-11.
37. Lindner V, Olson NE, Clowes AW, Reidy MA. Inhibition of smooth muscle cell proliferation in injured rat arteries. Interaction of heparin with basic fibroblast growth factor. J Clin Invest 1992; 90: 2044-9.
38. Clowes AW, Clowes MM. Kinetics of cellular proliferation after arterial injury: IV. Heparin inhibits rat smooth muscle mitogenesis and migration. Circ Res 1986; 58: 839-45.
39. Lindner V, Reidy MA. Proliferation of smooth muscle cells after vascular injury is inhibited by an antibody against basic fibroblast growth factor. Proc Natl Acad Sci USA 1991; 88: 3739-43.
40. Lundergan C, Foegh ML, Vargas R, Eufemio M, Bormes GW, Kot PA, Ramwell PW. Inhibition of myointimal proliferation of the rat carotid artery by the peptides angiopeptin and BIM 23034. Atherosclerosis 1989; 80: 49-55.
41. Ishizaka N, Kurokawa K, Taguchi J, Miki K, Ohno M. Inhibitory effect of a single local probucol administration on neointimal formation in balloon-injured rat carotid artery. Atherosclerosis 1995; 118: 53-6.
42. Seki J, Nishio M, Kato Y, Motoyama Y, Yoshida K. FK409, a new nitric-oxide donor, suppresses smooth muscle proliferation in rat model of balloon angioplasty. Atherosclerosis 1995; 117: 97-106.
43. 4. Impact of aspirin therapy. Circulation 1992; 86: 56-63.
44. Carry M, Korley V, Willerson JT, Weigelt L, Ford-Hutchinson AW, Tagari P. Increased urinary leukotriene excretion in patients with cardiac ischemia. In vivo evidence for 5-lipoxygenase activation. Circulation 1992; 85: 230-6.
45. Allen SP, Sampson AP, Piper PJ, Chester AH, Ohri SK, Yacoub MH. Enhanced excretion of urinary leukotriene E4 in coronary artery disease and after coronary artery bypass surgery. Coronary Artery Dis 1993; 4: 899-904.
46. Frölich JC, Fauler J, Tsikas D. Assessment of cysteinyl leukotriene synthesis in man. J Lipid Mediat Cell Signal 1994; 9: 75-8.
47. Hagihara H, Nomoto A, Mutoh S, Yamaguchi I, Ono T. Role of inflammatory responses in initiation of atherosclerosis: effects of anti-inflammatory drugs on cuff-induced leukocyte accumulation and intimal thickening of rabbit carotid artery. Atherosclerosis 1991; 91: 107-16.
48. Barnes PJ, Adcock I. Anti-inflammatory actions of steroids: molecular mechanisms. Trends Pharmacol Sci 1993; 14: 436-41.
49. Sebaldt RJ, Sheller JR, Oates JA, Roberts II LJ, FitzGerald GA. Inhibition of eicosanoid biosynthesis by glucocorticoids in humans. Proc Natl Acad Sci USA 1990; 87: 6974-8.
50. Berk BC, Gordon JB, Alexander RW. Pharmacologic roles of heparin and glucocorticoids to prevent restenosis after coronary angioplasty. J Am Coll Cardiol 1991; 17: 111B-7B.
51. Noveral JP, Grunstein MM. Role and mechanism of thromboxane-induced proliferation of cultured airway smooth muscle cells. Am J Physiol 1992; 263: L555-61.
52. Ip JH, Fuster V, Israel D, Badimon L, Badimon J, Chesebro JH. The role of platelets, thrombin and hyperplasia in restenosis after coronary angioplasty. J Am Coll Cardiol 1991; 17: 77B-88B.
53. Dethlefsen SM, Shepro D, D'Amore PA. Arachidonic acid metabolites in bFGF-, PDGF-, and serum-stimulated vascular cell growth. Exp Cell Res 1994; 212: 262-73.
54. Roth DM, Lefer AM. Studies on the mechanism of leukotriene induced coronary artery constriction. Prostaglandins 1983; 26: 573-81.
55. Muldoon LL, Dinerstein RJ, Villereal ML. Intracellular pH in human fibro-blasts: effect of mitogens, A23187, and phospholipase activation. Am J Physiol 1985; 249: C140-8.