메뉴 건너뛰기




Volumn 28, Issue 22, 1999, Pages 1182-1187

Cyclooxygenase-2 specific inhibitors: A revolution?;Inhibiteurs specifiques de la cyclooxygenase-2: Une revolution?

Author keywords

[No Author keywords available]

Indexed keywords

CELECOXIB; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; NONSTEROID ANTIINFLAMMATORY AGENT; ROFECOXIB; UNCLASSIFIED DRUG; PROSTAGLANDIN SYNTHASE INHIBITOR;

EID: 0033583883     PISSN: 07554982     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (3)

References (59)
  • 1
    • 0015237292 scopus 로고
    • Inhibition of prostaglandin synthesis as a mechanism of action for the aspirin-like drugs
    • Vane JR. Inhibition of prostaglandin synthesis as a mechanism of action for the aspirin-like drugs. Nature 1971 ; 231:232-5.
    • (1971) Nature , vol.231 , pp. 232-235
    • Vane, J.R.1
  • 2
    • 0031770223 scopus 로고    scopus 로고
    • Cyclooxygenases and cyclooxygenase inhibitors: Is a new class of drugs in the making?
    • Berenbaum F. Cyclooxygenases and cyclooxygenase inhibitors: is a new class of drugs in the making? Rev Rhum Engl Ed 1998 ; 65:634-40.
    • (1998) Rev Rhum Engl Ed , vol.65 , pp. 634-640
    • Berenbaum, F.1
  • 4
    • 0028009093 scopus 로고
    • The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1
    • Picot D, Loll PJ, Garavito RM. The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1. Nature 1994 ; 367:243-9.
    • (1994) Nature , vol.367 , pp. 243-249
    • Picot, D.1    Loll, P.J.2    Garavito, R.M.3
  • 5
    • 0030461132 scopus 로고    scopus 로고
    • Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents
    • Kurumbail RG, Stevens AM, Gierse JK et al. Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents. Nature 1996 ; 384:644-8.
    • (1996) Nature , vol.384 , pp. 644-648
    • Kurumbail, R.G.1    Stevens, A.M.2    Gierse, J.K.3
  • 6
    • 0029899186 scopus 로고    scopus 로고
    • A single amino acid difference between cyclooxygenase-1 (COX-1) and -2 (COX-2) reverses the selectivity of COX-2 specific inhibitors
    • Gierse JK, McDonald JJ, Hauser SD, Rangwala SH, Koboldt CM, Seibert K. A single amino acid difference between cyclooxygenase-1 (COX-1) and -2 (COX-2) reverses the selectivity of COX-2 specific inhibitors. J Biol Chem 1996; 271:15810-14.
    • (1996) J Biol Chem , vol.271 , pp. 15810-15814
    • Gierse, J.K.1    McDonald, J.J.2    Hauser, S.D.3    Rangwala, S.H.4    Koboldt, C.M.5    Seibert, K.6
  • 9
    • 0023968630 scopus 로고
    • Primary structure of prostaglandin G/H synthase from sheep vesicular gland determined from the complementary DNA sequence
    • DeWitt DL, Smith WL. Primary structure of prostaglandin G/H synthase from sheep vesicular gland determined from the complementary DNA sequence. Proc Natl Acad Sci 1988 ; 85:1412-16.
    • (1988) Proc Natl Acad Sci , vol.85 , pp. 1412-1416
    • DeWitt, D.L.1    Smith, W.L.2
  • 10
    • 0023855416 scopus 로고
    • Isolation and characterization of the complementary DNA for sheep seminal vesicle prostaglandin endoperoxide synthase (cyclooxygenase)
    • Merlie JP, Fagan D, Mudd J, Needleman P. Isolation and characterization of the complementary DNA for sheep seminal vesicle prostaglandin endoperoxide synthase (cyclooxygenase). J Biol Chem 1988 ; 263:3550-3
    • (1988) J Biol Chem , vol.263 , pp. 3550-3553
    • Merlie, J.P.1    Fagan, D.2    Mudd, J.3    Needleman, P.4
  • 11
    • 0024818522 scopus 로고
    • Cloning of human gene encoding prostaglandin endoperoxide synthase and primary structure of the enzyme
    • Yokohama C, Tanabe T. Cloning of human gene encoding prostaglandin endoperoxide synthase and primary structure of the enzyme. Biochem Biophys Res Commun 1989 ; 165:888-94.
    • (1989) Biochem Biophys Res Commun , vol.165 , pp. 888-894
    • Yokohama, C.1    Tanabe, T.2
  • 12
    • 0027293391 scopus 로고
    • Expression of mRNA for cyclooxygenase-1 and cyclooxygenase-2 in human tissues
    • O'Neill GP, Ford-Hutchinson AW. Expression of mRNA for cyclooxygenase-1 and cyclooxygenase-2 in human tissues. FEBS Lett 1993 ; 330:156-60.
    • (1993) FEBS Lett , vol.330 , pp. 156-160
    • O'Neill, G.P.1    Ford-Hutchinson, A.W.2
  • 13
    • 0027141004 scopus 로고
    • Cloning of two isoforms of rat cyclooxygenase: Differential regulation of their expression
    • Feng L, Sun W, Xia Y et al. Cloning of two isoforms of rat cyclooxygenase: differential regulation of their expression. Arch Biochem Biophys 1993 ; 307:361-8.
    • (1993) Arch Biochem Biophys , vol.307 , pp. 361-368
    • Feng, L.1    Sun, W.2    Xia, Y.3
  • 15
    • 0031689543 scopus 로고    scopus 로고
    • Cyclooxygenase in biology and disease
    • Dubois RN, Abramson SB, Crofford L et al. Cyclooxygenase in biology and disease. FASEB J 1998 ; 12:1063-73.
    • (1998) FASEB J , vol.12 , pp. 1063-1073
    • Dubois, R.N.1    Abramson, S.B.2    Crofford, L.3
  • 16
    • 0028959950 scopus 로고
    • Regulation of prostaglandin endoperoxide synthase (cyclooxygenase) isozyme expression
    • Goppelt-Struebe M. Regulation of prostaglandin endoperoxide synthase (cyclooxygenase) isozyme expression. Prostaglandins Leukot Essent Fatty Acids 1995 ; 52:213-22.
    • (1995) Prostaglandins Leukot Essent Fatty Acids , vol.52 , pp. 213-222
    • Goppelt-Struebe, M.1
  • 17
    • 0029888972 scopus 로고    scopus 로고
    • Selective inhibition of cyclooxygenase (COX)-2 reverses inflammation of COX-2 and interleukin-6 in rat adjuvant arthritis
    • Anderson GD, Hauser SD, McGarity KL, Bremer ME, Isakson PC, Gregory S. Selective inhibition of cyclooxygenase (COX)-2 reverses inflammation of COX-2 and interleukin-6 in rat adjuvant arthritis. J Clin Invest 1996 ; 97:2672-9.
    • (1996) J Clin Invest , vol.97 , pp. 2672-2679
    • Anderson, G.D.1    Hauser, S.D.2    McGarity, K.L.3    Bremer, M.E.4    Isakson, P.C.5    Gregory, S.6
  • 18
    • 0030945182 scopus 로고    scopus 로고
    • Superinduction of cyclooxygenase-2 activity in human osteoarthritis-affected cartilage. Influence of nitric oxide
    • Amin AR, Attur M, Patel RN et al. Superinduction of cyclooxygenase-2 activity in human osteoarthritis-affected cartilage. Influence of nitric oxide. J Clin Invest 1997 ; 99:1231-7.
    • (1997) J Clin Invest , vol.99 , pp. 1231-1237
    • Amin, A.R.1    Attur, M.2    Patel, R.N.3
  • 19
    • 0028173131 scopus 로고
    • IL-1-induced prostaglandin E2 biosynthesis in human synovial cells involves the activation of cytosolic phospholipase A2 and cyclooxygenase-2
    • Angel J, Berenbaum F, Le Denmat C, Nevalainen T, Masliah J, Fournier C. IL-1-induced prostaglandin E2 biosynthesis in human synovial cells involves the activation of cytosolic phospholipase A2 and cyclooxygenase-2. Eur J Biochem 1994 ; 226:125-31.
    • (1994) Eur J Biochem , vol.226 , pp. 125-131
    • Angel, J.1    Berenbaum, F.2    Le Denmat, C.3    Nevalainen, T.4    Masliah, J.5    Fournier, C.6
  • 20
    • 0028213334 scopus 로고
    • Cyclooxygenase-1 and -2 expression in rheumatoid synovial tissues. Effects of interleukin-1 beta, phorbol ester, and corticosteroids
    • Crofford LJ, Wilder RL, Ristimaki AP et al. Cyclooxygenase-1 and -2 expression in rheumatoid synovial tissues. Effects of interleukin-1 beta, phorbol ester, and corticosteroids. J Clin Invest 1994 ; 93:1095-101.
    • (1994) J Clin Invest , vol.93 , pp. 1095-1101
    • Crofford, L.J.1    Wilder, R.L.2    Ristimaki, A.P.3
  • 21
    • 0029785026 scopus 로고    scopus 로고
    • Expression of cyclooxygenase-2 in human and an animal model of rheumatoid arthritis
    • Kang RY, Freire-Moar J, Sigal E, Chu CQ. Expression of cyclooxygenase-2 in human and an animal model of rheumatoid arthritis. Br J Rheumatol 1996 ; 35:711-8.
    • (1996) Br J Rheumatol , vol.35 , pp. 711-718
    • Kang, R.Y.1    Freire-Moar, J.2    Sigal, E.3    Chu, C.Q.4
  • 22
    • 0026531534 scopus 로고
    • In vivo cyclooxygenase expression in synovial tissues of patients with rheumatoid arthritis and osteoarthritis and rats with adjuvant and streptococcal cell wall arthritis
    • Sano H, Hla T, Maier JAM et al. In vivo cyclooxygenase expression in synovial tissues of patients with rheumatoid arthritis and osteoarthritis and rats with adjuvant and streptococcal cell wall arthritis. J Clin Invest 1992 ; 89:97-108.
    • (1992) J Clin Invest , vol.89 , pp. 97-108
    • Sano, H.1    Hla, T.2    Maier, J.A.M.3
  • 23
    • 0031961901 scopus 로고    scopus 로고
    • Expression of cyclooxygenase 1 and cyclooxygenase 2 in human synovial tissue: Differential elevation of cyclooxygenase 2 in inflammatory joint diseases
    • Siegle I, Klein T, Backman JT, Saal JG, Nusing RM, Fritz P. Expression of cyclooxygenase 1 and cyclooxygenase 2 in human synovial tissue: differential elevation of cyclooxygenase 2 in inflammatory joint diseases. Arthritis Rheum 1998 ; 41:122-9.
    • (1998) Arthritis Rheum , vol.41 , pp. 122-129
    • Siegle, I.1    Klein, T.2    Backman, J.T.3    Saal, J.G.4    Nusing, R.M.5    Fritz, P.6
  • 24
    • 0028934999 scopus 로고
    • Cyclooxygenase inductible : Du nouveau sur les relations entre anti-inflammatoires non stéroidiens et inhibition de la synthèse de prostaglandines
    • Terlain B, Jouzeau JY, Gillet P, Lecomte T Netter P. Cyclooxygenase inductible : du nouveau sur les relations entre anti-inflammatoires non stéroidiens et inhibition de la synthèse de prostaglandines. Presse Med 1995 ; 24:491-6.
    • (1995) Presse Med , vol.24 , pp. 491-496
    • Terlain, B.1    Jouzeau, J.Y.2    Gillet, P.3    Lecomte, T.4    Netter, P.5
  • 25
    • 0031034254 scopus 로고    scopus 로고
    • A classification of NSAIDs according to the relative inhibition of cyclooxygenase isoenzymes
    • Frölich JC. A classification of NSAIDs according to the relative inhibition of cyclooxygenase isoenzymes. Trends Pharmocol Sci 1997 ; 18:30-4.
    • (1997) Trends Pharmocol Sci , vol.18 , pp. 30-34
    • Frölich, J.C.1
  • 26
    • 84996056535 scopus 로고
    • Are there differences among nonsteroidal antiinflammatory drugs?
    • Furst DE. Are there differences among nonsteroidal antiinflammatory drugs? Arthritis Rheum 1994 ; 37:1-9.
    • (1994) Arthritis Rheum , vol.37 , pp. 1-9
    • Furst, D.E.1
  • 27
    • 0029813244 scopus 로고    scopus 로고
    • Cyclooxygenase 1 and 2 in rheumatic disease : Implications for nonsteroidal anti-inflammatory drug therapy
    • Spangler RS. Cyclooxygenase 1 and 2 in rheumatic disease : implications for nonsteroidal anti-inflammatory drug therapy. Semin Arthritis Rheum 1996 ; 26:435-46.
    • (1996) Semin Arthritis Rheum , vol.26 , pp. 435-446
    • Spangler, R.S.1
  • 28
    • 0031685519 scopus 로고    scopus 로고
    • Gastrointestinal tolerability of the COX2 inhibitor, meloxicam, in osteoarthritis patients : The meloxicam large scale international study safety assessment (MELISSA)
    • Hawkey C, Kahan A, Steinbruck K et al. Gastrointestinal tolerability of the COX2 inhibitor, meloxicam, in osteoarthritis patients : the meloxicam large scale international study safety assessment (MELISSA). Br J Rheumatol 1998 ; 37:937-45.
    • (1998) Br J Rheumatol , vol.37 , pp. 937-945
    • Hawkey, C.1    Kahan, A.2    Steinbruck, K.3
  • 29
    • 0028322893 scopus 로고
    • Selective inhibition of inducible cyclooxygenase 2 in vivo is anti-inflammatory and nonulcerogenic
    • Masferrer JL, Zweifel BS, Manning PT et al. Selective inhibition of inducible cyclooxygenase 2 in vivo is anti-inflammatory and nonulcerogenic Proc Natl Acad Sci USA 1994 ; 91:3228-32.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 3228-3232
    • Masferrer, J.L.1    Zweifel, B.S.2    Manning, P.T.3
  • 30
    • 0027944075 scopus 로고
    • Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain
    • Seibert K, Zhang Y, Leahy K et al. Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain. Proc Natl Acad Sci USA 1994 ; 91:12013-17.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 12013-12017
    • Seibert, K.1    Zhang, Y.2    Leahy, K.3
  • 31
    • 0029033219 scopus 로고
    • Pharmacology of a selective cyclooxygenase-2 inhibitor, L-745,337 : A novel nonsteroidal anti-inflammatory agent with an ulcerogenic sparing effect in rat and non human primate stomach
    • Chan CC, Boyce S, Brideau C et al. Pharmacology of a selective cyclooxygenase-2 inhibitor, L-745,337 : a novel nonsteroidal anti-inflammatory agent with an ulcerogenic sparing effect in rat and non human primate stomach. J Exp Pharmacol Ther 1995 ; 274:1531-7.
    • (1995) J Exp Pharmacol Ther , vol.274 , pp. 1531-1537
    • Chan, C.C.1    Boyce, S.2    Brideau, C.3
  • 32
    • 0033031331 scopus 로고    scopus 로고
    • COX-2 inhibitors
    • Hawkey CJ. COX-2 inhibitors. Lancet 1999 ; 353:307-14.
    • (1999) Lancet , vol.353 , pp. 307-314
    • Hawkey, C.J.1
  • 33
    • 0031680203 scopus 로고    scopus 로고
    • Preliminary study of the safety and efficacy of SC-58635, a novel cyclooxygenase 2 inhibitor: Efficacy and safety in two placebo-controlled trials in osteoarthritis and rheumatoid arthritis, and studies of gastrointestinal and platelet effects
    • Simon LS, Lanza FL, Lipsky PE et al. Preliminary study of the safety and efficacy of SC-58635, a novel cyclooxygenase 2 inhibitor: efficacy and safety in two placebo-controlled trials in osteoarthritis and rheumatoid arthritis, and studies of gastrointestinal and platelet effects. Arthritis Rheum 1998 ; 41:1591-602.
    • (1998) Arthritis Rheum , vol.41 , pp. 1591-1602
    • Simon, L.S.1    Lanza, F.L.2    Lipsky, P.E.3
  • 34
    • 0031924535 scopus 로고    scopus 로고
    • COX-2 inhibitors for colorectal cancer
    • Elder DJ, Paraskeva C. COX-2 inhibitors for colorectal cancer. Nat Med 1998 ; 4:392-3.
    • (1998) Nat Med , vol.4 , pp. 392-393
    • Elder, D.J.1    Paraskeva, C.2
  • 35
    • 0030606299 scopus 로고    scopus 로고
    • Suppression of intestinal polyposis in ApcD716 knockout mice by inhibition of cyclooxygenase 2 (COX-2)
    • Oshima M, Dinchuk JE, Kargman SL et al. Suppression of intestinal polyposis in ApcD716 knockout mice by inhibition of cyclooxygenase 2 (COX-2). Cell 1996 ; 87:803-9.
    • (1996) Cell , vol.87 , pp. 803-809
    • Oshima, M.1    Dinchuk, J.E.2    Kargman, S.L.3
  • 36
    • 0032190264 scopus 로고    scopus 로고
    • Cyclooxygenase and inflammation in Alzheimer's disease: Experimental approaches and clinical interventions
    • Pasinetti GM. Cyclooxygenase and inflammation in Alzheimer's disease: experimental approaches and clinical interventions. J Neurosci Res 1998 ; 54:1-6.
    • (1998) J Neurosci Res , vol.54 , pp. 1-6
    • Pasinetti, G.M.1
  • 37
    • 0030799478 scopus 로고    scopus 로고
    • Role of intestinal epithelial cells in the host secretory response to infection by invasive bacteria: Bacterial entry induces epithelial prostaglandin H synthase-2 expression and prostaglandin E2 and F2a production
    • Eckmann L, Stenson WF, Savidge TC et al. Role of intestinal epithelial cells in the host secretory response to infection by invasive bacteria: bacterial entry induces epithelial prostaglandin H synthase-2 expression and prostaglandin E2 and F2a production. J Clin Invest 1997 ; 100:296-309.
    • (1997) J Clin Invest , vol.100 , pp. 296-309
    • Eckmann, L.1    Stenson, W.F.2    Savidge, T.C.3
  • 38
    • 0032160712 scopus 로고    scopus 로고
    • Role of cyclooxygenase-2 in the healing of gastric ulcers in rats
    • Shigeta J, Takahashi S, Okabe S. Role of cyclooxygenase-2 in the healing of gastric ulcers in rats. J Pharmacol Exp Ther 1998 ; 286:1383-90.
    • (1998) J Pharmacol Exp Ther , vol.286 , pp. 1383-1390
    • Shigeta, J.1    Takahashi, S.2    Okabe, S.3
  • 39
    • 0031052116 scopus 로고    scopus 로고
    • Induction of cyclooxygenase 2 in gastric mucosal lesions and its inhibition by the specific antagonist delays healing in mice
    • Mizuno H, Sakamoto C, Matsuda K et al. Induction of cyclooxygenase 2 in gastric mucosal lesions and its inhibition by the specific antagonist delays healing in mice. Gastroenterology 1997 ; 112:387-97.
    • (1997) Gastroenterology , vol.112 , pp. 387-397
    • Mizuno, H.1    Sakamoto, C.2    Matsuda, K.3
  • 40
    • 15644382984 scopus 로고    scopus 로고
    • Helicobacter pylon up-regulates cyclooxygenase-2 mRMA expression and prostaglandin E2 synthesis in MKN 28 gastric mucosal cells in vitro
    • Romano M, Ricci V, Memoli A et al. Helicobacter pylon up-regulates cyclooxygenase-2 mRMA expression and prostaglandin E2 synthesis in MKN 28 gastric mucosal cells in vitro. J Biol Chem 1998 ; 273:28560-3.
    • (1998) J Biol Chem , vol.273 , pp. 28560-28563
    • Romano, M.1    Ricci, V.2    Memoli, A.3
  • 41
    • 0032418119 scopus 로고    scopus 로고
    • Helicobacter pylori infection induces cyclooxygenase-2 expression in human gastric mucosa
    • Sawaoka H, Kawano S, Tsuji S et al. Helicobacter pylori infection induces cyclooxygenase-2 expression in human gastric mucosa. Prostaglandins Leukot Essent Fatty Acids 1998 ; 59:313-6.
    • (1998) Prostaglandins Leukot Essent Fatty Acids , vol.59 , pp. 313-316
    • Sawaoka, H.1    Kawano, S.2    Tsuji, S.3
  • 42
    • 0030875018 scopus 로고    scopus 로고
    • Expression of cyclooxygenase-2 mRNA in active inflammatory bowel disease
    • Hendel J, Nielsen OH Expression of cyclooxygenase-2 mRNA in active inflammatory bowel disease. Am J Gastroenterol 1997 ; 92:1170-3
    • (1997) Am J Gastroenterol , vol.92 , pp. 1170-1173
    • Hendel, J.1    Nielsen, O.H.2
  • 43
    • 0029907525 scopus 로고    scopus 로고
    • Exacerbation of inflammation-associated colonic injury in rat through inhibition of cyclooxygenase-2
    • Reuter BK, Asfaha S, Buret A, Sharkey KA, Wallace JL. Exacerbation of inflammation-associated colonic injury in rat through inhibition of cyclooxygenase-2. J Clin Invest 1996 ; 98:2076-85.
    • (1996) J Clin Invest , vol.98 , pp. 2076-2085
    • Reuter, B.K.1    Asfaha, S.2    Buret, A.3    Sharkey, K.A.4    Wallace, J.L.5
  • 44
    • 0032076219 scopus 로고    scopus 로고
    • Cyclooxygenase-1 and cyclooxygenase-2 selectivity of widely used non-steroidal antiinflammatory drugs
    • Cryer B, Feldman M. Cyclooxygenase-1 and cyclooxygenase-2 selectivity of widely used non-steroidal antiinflammatory drugs. Am J Med 1998 ; 104:413-21.
    • (1998) Am J Med , vol.104 , pp. 413-421
    • Cryer, B.1    Feldman, M.2
  • 45
    • 0028807498 scopus 로고
    • Prostaglandin synthase 2 gene disruption causes several renal pathology in the mouse
    • Morham SG, Langenbach R, Loftin CD et al. Prostaglandin synthase 2 gene disruption causes several renal pathology in the mouse. Cell 1995 ; 83:473-82.
    • (1995) Cell , vol.83 , pp. 473-482
    • Morham, S.G.1    Langenbach, R.2    Loftin, C.D.3
  • 46
    • 0028818913 scopus 로고
    • Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase-11
    • Dinchuk JE, Car BD, Focht RJ et al. Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase-11. Nature 1995 ; 378:406-9.
    • (1995) Nature , vol.378 , pp. 406-409
    • Dinchuk, J.E.1    Car, B.D.2    Focht, R.J.3
  • 47
    • 0031679914 scopus 로고    scopus 로고
    • Interspecies differences in renal localization of cyclooxygenase isoforms: Implications in nonsteroidal antiinflammatory drug-related nephrotoxicity
    • Khan KN, Venturini CM, Bunch RT et al. Interspecies differences in renal localization of cyclooxygenase isoforms: implications in nonsteroidal antiinflammatory drug-related nephrotoxicity. Toxicol Pathol 1998 ; 26:612-20.
    • (1998) Toxicol Pathol , vol.26 , pp. 612-620
    • Khan, K.N.1    Venturini, C.M.2    Bunch, R.T.3
  • 48
    • 0029589755 scopus 로고
    • The role of prostaglandins in labor and delivery
    • O'Brien WF. The role of prostaglandins in labor and delivery. Clin Perinatol 1995 ; 22:973-84.
    • (1995) Clin Perinatol , vol.22 , pp. 973-984
    • O'Brien, W.F.1
  • 49
    • 0032896654 scopus 로고    scopus 로고
    • Cyclooxygenase-2 plays a significant role in regulating the tone of the fetal lamb ductus artenosus
    • Clyman RI, Hardy P, Waleh N et al. Cyclooxygenase-2 plays a significant role in regulating the tone of the fetal lamb ductus artenosus. Am J Physiol 1999 ; 276:R913-21
    • (1999) Am J Physiol , vol.276
    • Clyman, R.I.1    Hardy, P.2    Waleh, N.3
  • 50
    • 0029949756 scopus 로고    scopus 로고
    • Developmental expression of the cyclo-oxygenase-1 and cyclo-oxygenase-2 genes in the peri-implantation mouse uterus and their differential regulation by the blastocyst and ovarian steroids
    • Chakraborty I, Das SK, Wang J, Dey SK. Developmental expression of the cyclo-oxygenase-1 and cyclo-oxygenase-2 genes in the peri-implantation mouse uterus and their differential regulation by the blastocyst and ovarian steroids. J Mol Endocrinol 1996 ; 16:107-22.
    • (1996) J Mol Endocrinol , vol.16 , pp. 107-122
    • Chakraborty, I.1    Das, S.K.2    Wang, J.3    Dey, S.K.4
  • 51
    • 0030993393 scopus 로고    scopus 로고
    • Expression of cyclooxygenase-1 and -2 in ovine endometrium during the estrous cycle and early pregnancy
    • Charpigny C, Reinaud P, Tamby JP et al. Expression of cyclooxygenase-1 and -2 in ovine endometrium during the estrous cycle and early pregnancy. Endocrinology 1997 ; 138:2163-71.
    • (1997) Endocrinology , vol.138 , pp. 2163-2171
    • Charpigny, C.1    Reinaud, P.2    Tamby, J.P.3
  • 52
    • 0030702122 scopus 로고    scopus 로고
    • Multiple female reproductive failures in cyclooxygenase 2-deficient mice
    • Lim H, Paria BC, Das SK et al. Multiple female reproductive failures in cyclooxygenase 2-deficient mice. Cell 1997; 91:197-208.
    • (1997) Cell , vol.91 , pp. 197-208
    • Lim, H.1    Paria, B.C.2    Das, S.K.3
  • 53
    • 0344566622 scopus 로고    scopus 로고
    • Prescription d'un AINS en rhumatologie
    • (Elsevier, Paris), Akos Encyclopédie, Pratique de Médecine, 7-0905, 4 p.
    • Berenbaum F. Prescription d'un AINS en rhumatologie. Encycl Méd Chir (Elsevier, Paris), Akos Encyclopédie, Pratique de Médecine, 7-0905, 1998, 4 p.
    • (1998) Encycl Méd Chir
    • Berenbaum, F.1
  • 54
    • 0029862157 scopus 로고    scopus 로고
    • The mechanisms of action of NSAIDs in analgesia
    • Cashman JN. The mechanisms of action of NSAIDs in analgesia. Drugs 1996 ; 52:13-23.
    • (1996) Drugs , vol.52 , pp. 13-23
    • Cashman, J.N.1
  • 55
    • 0029980957 scopus 로고    scopus 로고
    • New pharmacological strategies for pain relief
    • Dray A, Urban L. New pharmacological strategies for pain relief. Annu Rev Pharmacol Toxicol 1996 ; 16:253-80.
    • (1996) Annu Rev Pharmacol Toxicol , vol.16 , pp. 253-280
    • Dray, A.1    Urban, L.2
  • 56
    • 0028843881 scopus 로고
    • Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration
    • Langenbach R., Morham SG., Tiano HF et al. Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration. Cell 1995 ; 83:483-92.
    • (1995) Cell , vol.83 , pp. 483-492
    • Langenbach, R.1    Morham, S.G.2    Tiano, H.F.3
  • 57
    • 13144260638 scopus 로고    scopus 로고
    • Pharmacological analysis of cyclooxygenase-1 in inflammation
    • Smith CJ, Zhang Y, Koboldt CM et al. Pharmacological analysis of cyclooxygenase-1 in inflammation. Proc Natl Acad Sci USA 1998 ; 95:13313-18.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 13313-13318
    • Smith, C.J.1    Zhang, Y.2    Koboldt, C.M.3
  • 58
    • 0028322893 scopus 로고
    • Selective inhibition of inducible cyclooxygenase 2 in vivo is antiinflammatory and nonulcerogenic
    • Seibert JL, Zweifel BS, Manning PT et al. Selective inhibition of inducible cyclooxygenase 2 in vivo is antiinflammatory and nonulcerogenic. Proc Natl Acad Sci USA 1994 ; 91:3228-32.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 3228-3232
    • Seibert, J.L.1    Zweifel, B.S.2    Manning, P.T.3
  • 59
    • 0032439786 scopus 로고    scopus 로고
    • Expression of cyclooxygenase isoforms in the rat spinal cord and their regulation during adjuvant-induced arthritis
    • Beiche F, Brune K, Geisslinger G, Goppelt-Struebe M. Expression of cyclooxygenase isoforms in the rat spinal cord and their regulation during adjuvant-induced arthritis. Inflamm Res 1998 ; 47:482-7.
    • (1998) Inflamm Res , vol.47 , pp. 482-487
    • Beiche, F.1    Brune, K.2    Geisslinger, G.3    Goppelt-Struebe, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.