Increased transcription of the astrocyte gene GFAP during middle-age is attenuated by food restriction: Implications for the role of oxidative stress

Free Radical Biology and Medicine

Volumn 23, Issue 3, 1997, Pages 524-528

  Morgan, Todd E ^a   Rozovsky, Irina ^a   Goldsmith, Sarah K ^a   Stone, David J ^a   Yoshida, Toru ^a   Finch, Caleb E ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Aging; Cysteamine; Food restriction; GFAP transcription; Hydrogen peroxide; Microglia; Oxidative stress

Indexed keywords

GLIAL FIBRILLARY ACIDIC PROTEIN; HYDROGEN PEROXIDE; MERCAPTAMINE; MESSENGER RNA;

ADOLESCENT; AGED; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN INJURY; CONTROLLED STUDY; DIET RESTRICTION; GENE EXPRESSION; GENETIC TRANSCRIPTION; HIPPOCAMPUS; IN SITU HYBRIDIZATION; INTERMEDIATE FILAMENT; LIFESPAN; MICROGLIA; NEWBORN; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

AGING; ANIMALS; ASTROCYTES; CELLS, CULTURED; CYSTEAMINE; DIET; GENE EXPRESSION REGULATION; GLIAL FIBRILLARY ACIDIC PROTEIN; HIPPOCAMPUS; HYDROGEN PEROXIDE; IMMUNOHISTOCHEMISTRY; LIPOPOLYSACCHARIDES; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; OXIDATIVE STRESS; RATS; RATS, INBRED STRAINS; RNA, MESSENGER; TRANSCRIPTION, GENETIC;

ANIMALIA; GILA;

EID: 0030995379     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(97)00120-2     Document Type: Article

References (29)

1. Weindruch R., Walford R. The retardation of aging and disease by dietary restriction. 1988;C.C. Thomas, Springfield, IL.
2. Yu B. P. Modulation of aging processes by dietary restriction. 1994;CRC Press, Boca Raton, FL.
3. Heydari A. R., Wu B., Takahashi R., Strong R., Richardson A. Expression of heat shock protein 70 is altered by age and diet at the level of transcription. Mol. Cell. Biol. 13:1993;2909-2918.
4. Warner H. R., Fernandes G., Wang E. A unifying hypothesis to explain the retardation of aging and tumorigenesis by caloric restriction. J. Gerontol. 50A:1995;B107-B109.
5. Choi J.-H., Yu B. P. Brain synaptosomal aging: free radicals and membrane fluidity. Free Radic. Biol. Med. 18:1995;133-139.
6. Tacconi M. T., Lligona L., Salmona M., Pitsikas N., Algeri S. Aging and food restriction: Effect on lipids of cerebral cortex. Neurobiol. Aging. 12:1991;55-59.
7. Coleman P. D., Flood D. G. Neuron numbers and dendritic extent in normal aging and Alzheimer's disease. Neurobiol. Aging. 8:1987;521-545.
8. Laping N. J., Teter B., Nichols N. R., Rozovsky I., Finch C. E. Glial fibrillary acidic protein: regulation by hormones, cytokines, and growth factors. Brain Pathol. 4:1994;259-274.
9. Nichols N. R., Day J. R., Laping N. J., Johnson S. A., Finch C. E. GFAP mRNA increases with age in rat and human brain. Neurobiol. Aging. 14:1993;421-429.
10. Major, D. E.; Kesslak, J. P.; Cotman, C. W.; Finch, C. E.; Day, J. R. Life-long dietary restriction attenuates age-related increases in glial fibrillary acidic protein (GFAP) mRNA in the rat hippocampus. Brain Res., in press; 1997.
11. Yoshida T., Goldsmith S., Morgan T. E., Stone D., Finch C. E. Transcription supports age-related increases of GFAP expression in the male rat brain. Neurosci. Lett. 215:1996;107-110.
12. Pitsikas N., Algeri S. Deterioration of spatial and nonspatial reference and working memory in aged rats: protective effect of life-long calorie restriction. J. Gerontol. 13:1992;369-373.
13. Hori N., Hirotsu I., Davis P. J., Carpenter D. O. Long-term potentiation is lost in aged rats, but preserved by calorie restriction. NeuroReport. 3:1992;1085-1088.
14. Finch C. E. Neuron atrophy during aging: programmed or sporadic? Trends Neurosci. 16:1993;104-110.
15. Finch C. E. Corrigenda: aged dogs, space, and scissors. Trends Neurosci. 16:1993;352.
16. West M. J. Regionally specific loss of neurons in the aging human hippocampus. Neurobiol. Aging. 14:1993;287-293.
17. Gallagher M., Landfield P. W., McEwen B., Meaney M. J., Rapp P. R., Sapolsky R. M., West M. J. Hippocampal neurodegeneration in aging. Science. 274:1996;484-485.
18. Wenzel J., Lammert G., Meyer U., Krug M. The influence of long-term potentiation on the spatial relationship between astrocyte processes and potentiated synapses in the dentate gyrus neuropil of rat brain. Brain Res. 560:1991;122-131.
19. Sprott R. L., Austad S. N. Animal models for aging research. Schneider E. L., Rowe J. W. Handbook of the biology of aging. 4th edition:1996;3-23 Academic Press, San Diego, CA.
20. Rozovsky I., Laping N. J., O'Callaghan J. P., Finch C. E. Transcriptional regulation of GFAP expression by corticosterone in vitro is influenced by the duration of time in culture and by neuron-astrocyte interactions. Endocrinology. 136:1995;2066-2073.
21. Morgan T. E., Laping N. J., Rozovsky I., Oda T., Hogan H., Finch C. E., Pasinetti G. M. Clusterin expression in astrocytes is influenced by TGF- β1 and heterotypic cell interactions. J. Neuroimmunol. 58:1995;101-110.
22. Perry V., Matyszak M., Fearn S. Altered antigen expression of microglia in aged rodent CNS. GLIA. 7:1993;60-67.
23. Yan S.-D., Chen X., Schmidt A.-M., Brett J., Godman G., Zou Y.-S., Scott C. W., Caputo C., Frappier T., Smith M. A., Perry G., Yen S.-H., Stern D. Glycated tau protein in Alzheimer disease: A mechanism for induction of oxidant stress. Proc. Natl. Acad. Sci. USA. 91:1994;7787-7795.
24. Meda L., Cassatella M. A., Szendrei G. I., Villalba M., Ferrari D., Rossi F. Activation of microglial cells by β -amyloid protein and interferon- γ Nature. 374:1995;647-650.
25. Munday R. Toxicity of thiols and disulphides: involvement of free-radical species. Free Radic. Biol. Med. 7:1989;659-673.
26. Schipper H. Astrocytes, brain aging, neurodegeneration. Neurobiol. Aging. 17:1996;467-480.
27. Smith M. A., Sayre L. M., Monnier V. M., Perry G. Radical AGEing in Alzheimer's disease. TiNS. 18:1995;172-177.
28. Maher P., Davis J. B. The role of monoamine metabolism in oxidative glutamate toxicity. J. Neurosci. 16:1996;6394-6401.
29. Klebanov S., Diais S., Stavinoha W. B., Suh Y., Nelson J. F. Hyperadrenocorticism, attenuated inflammation, and the life-prolonging action of food restriction in mice. J. Gerontol. Biol. Sci. 50A:1995;B78-B82.