Ectopic activation of lymphoid high mobility group-box transcription factor TCF-1 and overexpression in colorectal cancer cells

International Journal of Cancer

Volumn 72, Issue 4, 1997, Pages 625-630

  Mayer, Karin ^a   Hieronymus, Thomas ^a   Castrop, Jan ^b   Clevers, Hans ^b   Ballhausen, Wolfgang G ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; HIGH MOBILITY GROUP PROTEIN; TRANSCRIPTION FACTOR;

ARTICLE; COLORECTAL CANCER; GENE EXPRESSION REGULATION; GENE TARGETING; HUMAN; HUMAN CELL; PRIORITY JOURNAL; RNA SPLICING; SIGNAL TRANSDUCTION;

ALTERNATIVE SPLICING; BLOTTING, NORTHERN; COLORECTAL NEOPLASMS; DISEASE PROGRESSION; DNA-BINDING PROTEINS; HELA CELLS; HUMANS; LYMPHOID ENHANCER-BINDING FACTOR 1; POLYMERASE CHAIN REACTION; PROMOTER REGIONS (GENETICS); RNA, NEOPLASM; T CELL TRANSCRIPTION FACTOR 1; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED;

EID: 0030831275     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19970807)72:4<625::AID-IJC13>3.0.CO;2-A     Document Type: Article

References (21)

1. BEHRENS, J., VAKAET, L., FRIIS, R., WINTERHAGER, E., VAN ROY, F., MAREEL, M. and BIRCHMEIER, W., Loss of epithelial differentiation and gain of invasiveness correlates with tyrosine phosphorylation of the E-cadherin/β-catenin complex in cells transformed with a temperature-sensitive v-SRC gene. J. Cell Biol., 120, 757-766 (1993).
2. BEHRENS, J., VON KRIES, J.P., KUHL, M., BRUHM, L., WEDLICH, D., GROSSCHEDL, P. and BIRCHMEIER, W., Functional interaction of beta-catenin with the transcription factor LEF-1. Nature (Lond.), 382, 638-642 (1996).
3. CASTROP, J., VAN WICHEN, D., KOOMANS-BITTER, M., VAN DE WETERING, M., DE WEGER, R., VAN DONGEN, J. and CLEVERS, H., The human TCF-1 gene encodes a nuclear DNA-binding protein uniquely expressed in normal and neoplastic T-lineage lymphocytes. Blood, 86, 3050-3059 (1995).
4. GIESE, K. and GROSSCHEDL, R., LEF-1 contains an activation domain that stimulates transcription only in a specific context of factor-binding sites. EMBO J., 12, 4667-4676 (1993).
5. GUMBINER, B.M., Signal transduction of beta-catenin. Curr. Opin. Cell Biol., 7, 634-640 (1995).
6. HÜLSKEN, J., BIRCHMEIER, W. and BEHRENS, J., E-cadherin and APC compete for the interaction with β-catenin and the cytoskeleton. J. Cell Biol., 127, 2061-2069 (1994).
7. KEMLER, R., From cadherins to catenins: cytoplasmic protein interactions and regulation of cell adhesion. Trends Genet., 9, 317-321 (1993).
8. KINZLER, K.W. and VOGELSTEIN, B., Lessons from hereditary colorectal cancer. Cell, 87, 159-170 (1996).
9. lck in metastatic colorectal cancer cells. Int. J. Oncol., 3, 369-373 (1993).
10. MAYER, K., WOLFF, E., CLEVERS, H. and BALLHAUSEN, W.G., The human high mobility group (HMG)-box transcription factor TCF-1: novel isoforms due to alternative splicing and usage of a new exon IXA. Biochim. biophys. Acta, 1263, 169-172 (1995).
11. MOLENAAR, M., VAN DE WETERING, M., OOSTERWEGEL, M., PETERSON-MADURO, J., GODSAVE, S., KORINEK, V., ROOSE, J., DESTREE, O. and CLEVERS, H., XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos. Cell, 86, 391-399 (1996).
12. OOSTERWEGEL, M., VAN DE WETERING, M., DOOIJES, D., KLOMP, L., WINOTO, A., GEORGOPOULOS, K., MEIJLINK, F. and CLEVERS, H., Cloning of murine TCF-1, a T cell specific transcription factor interacting with functional motifs in the CD3-ε and T cell receptor a enhancers. J. exp. Med., 173, 1133-1142 (1991).
13. RUBINFELD, B., ALBERT, I., PORFIRI, E., FIOL, C., MUNEMITSU, S. and POLAKIS, P., Binding of GSK3-beta to the APC-beta-catenin complex and regulation of complex assembly. Science, 272, 1023-1025 (1996).
14. TRAVIS, A., AMSTERDAM, A., BELANGER, C. and GROSSCHEDL, R., LEF-1, a gene encoding a lymphoid-specific protein with an HMG domain regulates T-cell receptor α enhancer function. Genes Develop., 5, 880-894 (1991).
15. VAN DE WETERING, M., CASTROP, J., KORINEK, V. and CLEVERS, H., Extensive alternative splicing and dual promoter usage generate Tcf-1 protein isoforms with differential transcription control properties. Mol. cell. Biol. 16, 745-752 (1996).
16. VAN DE WETERING, M. and CLEVERS, H., Sequence-specific interaction of the HMG box proteins TCF-1 and SRY occurs within the minor groove of a Watson-Crick double helix. EMBO J., 11, 3039-3044 (1992).
17. VAN DE WETERING, M., OOSTERWEGEL, M., DOOIJES, D. and CLEVERS, H., Identification and cloning of TCF-1, a T lymphocyte-specific transcription factor containing a sequence-specific HMG box. EMBO J., 10, 123-132 (1991).
18. VAN DE WETERING, M., OOSTERWEGEL, M., HOLSTEGE, F., DOOYES, D., SUIJKERBUIJK, R., GEURTS VAN KESSEL, A. and CLEVERS, H., The human T cell transcription factor-1 gene. J. biol. Chem., 267, 8530-8536 (1992).
19. VAN DE WETERING, M., OOSTERWEGEL, M., VAN NORREN, K. and CLEVERS, H., Sox-4, an SRY-like HMG box protein, is a transcriptional activator in lymphocytes. EMBO J., 12, 3847-3854 (1993).
20. VEILLETTE, A., FOSS, F.M., SAUSVILLE, E.A., BOLEN, J.B. and ROSEN, N., Expression of the lck tyrosine kinase gene in human colon carcinoma and other non-lymphoid human tumor cell lines. Oncogene Res., 1, 357-374 (1987).
21. WATERMAN, M.L., FISCHER, W.H. and JONES, K.A., A thymus-specific member of the HMG protein family regulates the human T cell receptor Cα enhancer. Genes Develop., 5, 656-669 (1991).